Recent news on Actos

Years Ago, Agency Was Warned of a Drug’s Risks  -  25 May 2007
Wilmington Morning Star,He was also an investigator in a study comparing Avandia with Actos, sponsored by Eli Lilly, that showed Actos had better effects on cholesterol than

The Rosiglitazone Aftermath: Legitimate Concerns or Hype?  -  25 May 2007
Medscape (subscription)And what effect will all this have on the other thiazolidinedione (TZD)--pioglitazone (Actos, Takeda)? Opinions on this also seem to vary.

The rosiglitazone aftermath: Legitimate concerns or hype?  -  25 May 2007
TheHeart.Org,And what effect will all this have on the other thiazolidinedione (TZD)—pioglitazone (Actos, Takeda)? Opinions on this also seem to vary.

Concerns about diabetes drug Avandia aren't new  -  May 23, 2007
Los Angeles Times,Zawisza, the FDA spokeswoman, said the prescribing literature for Avandia and Actos has been updated repeatedly to include warnings about the risks of heart

Doctors warn over Avandia scare  -  May 23, 2007
WFAA (subscription),He says there is an alternative called Actos but changing over to this medication may cause interim problems for diabetics. "A big mess. A phone call mess,

Which Medications for Type 2 Diabetes are Safe?  -  May 23, 2007
About - News & Issues,Avandia and Actos are in the class of thiazolidinediones, but there are several drug classes still available which do not cause cardiac side effects.

Actos drives growth at Takeda but Januvia threat is hovering  -  May 11, 2007
Pharma Times (subscription),Strong sales of the diabetes treatment Actos has helped Takeda Pharmaceutical Co, Japan's largest drugmaker, post a 7.2% increase in net income for the year

Takeda Full-Year Net Rises 7.2% on Sales of Actos Diabetes Drug  -  May 9, 2007
BloombergJapan's largest drugmaker, reported a 7.2 percent increase in full-year profit, spurred by higher US sales of its Actos diabetes pill.

Analysis Associates Avandia With Greater Risk of Heart Attack  -  May 21, 2007
Diabetes Health (press release),Earlier this year, the Cochrane Library published a meta-analysis of Actos (pioglitazone), a thiazolidinedione similar to Avandia, which implicated it in

Lilly stands to gain from GlaxoSmithKline's woes  -  May 22, 2007
Indianapolis Business Journal,Lilly and a Japanese partner have developed Actos, which is similar to Avandia. However, unlike GlaxoSmithKline’s drug, Actos doesn’t make a big difference

Nikkei rises on Sony and Takeda, banks surge  -  May 21, 2007
ReutersT: Quote, NEWS , Research) climbed 2.7 percent to 7960 yen on speculation that sales of its main earnings driver Actos will rise after a US study said a

Takeda Says Sales Growth May Slow on Drug Competition (Update2)  -  May 10, 2007
Bloomberg...s Januvia, will cut Actos's sales growth this year to about half the pace of 2007. Actos, first sold in 1999 for type 2 diabetes, accounted for a quarter of

Japan's Takeda Pharmaceuticals posts record group net profit  -  May 10, 2007
MarketWatchThursday reported a record group net profit for the second straight fiscal year with strong sales of its diabetes drug Actos and benefits from a weaker yen

Helps Takeda Post Record Earnings  -  May 10, 2007
Wall Street Journal (subscription),TOKYO -- Takeda Pharmaceutical Co. reported record group net profit for the second straight fiscal year, with strong sales of its diabetes drug Actos and

Diabetes Pill Tied to Heart Risks  -  May 22, 2007
Newsday,Only one other drug like it -- pioglitazone, sold as Actos and Actoplus Met by Takeda Pharmaceuticals -- is sold in the United States.

Rosiglitazone May Lower Risk of Lung Cancer and Boost ...  -  May 15, 2007
About - News & Issues,The diabetes drugs, rosiglitazone (Avandia) and pioglitazone (Actos) have been shown to reduce the incidence of lung cancer in a study that appeared in the

Diabetes pill linked to heart attacks  -  May 22, 2007
Portsmouth Herald News,Only one other drug like it — pioglitazone, sold as Actos and Actoplus Met by Takeda Pharmaceuticals — is sold in the United States.

Takeda profit up, sees bigger growth this year  -  May 9, 2007
ReutersActos sales have boomed in the United States, helped by Medicare system reforms that extended care for the elderly. Takeda, Japan's eighth-biggest company

Diabetes pill raises risk of heart attacks, study suggests, and ...  -  May 21, 2007
San Diego Union Tribune,Only one other drug like it – pioglitazone, sold as Actos and Actoplus Met by Takeda Pharmaceuticals – is sold in the United States.

Glaxo's Drug Disaster?  -  May 21, 2007
Forbes,Nissen is doing a study of Actos for Takeda and consults for most major pharmaceutical firms, but he gives all the fees drug makers send him to charity.

FDA Issues Safety Alert for Diabetes Drug Avandia  -  May 21, 2007
MyFox WGHP,Only one other drug like it -- pioglitazone, sold as Actos and Actoplus Met by Takeda pharmaceuticals -- is sold in the United States.

Diabetes Pill Tied to Heart Risks  -  May 21, 2007
phillyBurbs.com,Only one other drug like it , pioglitazone, sold as Actos and Actoplus Met by Takeda Pharmaceuticals , is sold in the United States.

ALERT: Diabetes Pill Tied to Heart Risks  -  May 21, 2007
WXYZ,Only one other drug like it—pioglitazone, sold as Actos and Actoplus Met by Takeda Pharmaceuticals—is sold in the United States.

Escondido concert to benefit military art installation  -  26 Apr 2007
North County Times,Moonlight Stage Productions has canceled "Actos," the free play reading it was scheduled to present through its WordsWork program on Monday at Vista's Avo

Application for an Additional Indication of Combination Therapy of ...  -  Apr 23, 2007
PipelineReview.com (press release),Actos suppresses the production of the glucose in the liver while improving the sensitivity to insulin in the peripheral tissues.

People with type 2 diabetes to have improved access to Actos  -  Mar 29, 2007
Antara (press release),A key improvement is that general practitioners can now write the initial prescription for Actos, under Special Authority. Previously only specialists (of

Diabetes Drugs Tied to Fractures in Women  -  Apr 17, 2007
Journal of American Medical Association (subscription),A warning from the US Food and Drug Administration (FDA) has linked pioglitazone (Actos), a thiazolidinedione prescribed for the treatment of type 2

Takeda says not in talks now with Abbott over TAP  -  Apr 11, 2007
Reuters.uk,Hasegawa said he saw US sales for Actos, a treatment for diabetes and the company's main earnings driver, climbing between 10 and 20 percent, albeit at the

Cost vs. compliance: Physicians encouraged to discuss prescriptions  -  Apr 15, 2007
American Medical News (subscription)He decided to add pioglitazone, a thiazolidinedione marketed as Actos, to the patient's armamentarium. The woman's blood sugar levels did not drop after

Drug Helps Lower Blood Sugar  -  Apr 2, 2007
WebMDWhen the study started, the patients were already taking the diabetes drugs Actos or Avandia. Some were also taking the diabetes drug metformin.

Byetta Approved for Use with TZDs  -  Apr 13, 2007
Diabetes Health (press release),Over 3.5 million type 2s are currently using oral TZDs, including Actos and Avandia, which control blood sugar by making muscle cells more sensitive to

Merck & Co's Janumet approved by the FDA  -  Apr 2, 2007
Pharma Times (subscription),...of oral diabetes medications, metformin or thiazolidinediones such as GlaxoSmithKline's Avandia (rosiglitazone) and Takeda/Lilly's Actos (pioglitazone).

Further step in battle with Type 2 diabetes  -  Mar 29, 2007
Scoop.co.nz,PHARMAC is giving more people the chance to access the Type 2 diabetes medicine pioglitazone (Actos). The medicine funding decision is PHARMAC’s latest

Lilly Reports Strong First-Quarter Results; Raises Full-Year Sales ...  -  Apr 16, 2007
Genetic Engineering News (press release),Excluding US Actos(R) revenue in both periods due to the expiration of Lilly's US marketing rights, worldwide sales for the quarter increased 17 percent.

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,Duetact is a mixture of Actos and glimepiride, marketed by Takeda since 2006. These pills are available with different doses of each component.

Japan drug industry indulges yen for biotech  -  Apr 19, 2007
International Herald Tribune,Takeda's Actos, the world's No. 2 diabetes medicine, will have generic challengers within four years. "There is limited growth in Japan itself,

Pharma Sector: Few Newsmakers Of The Week - Pfizer, Merck, Glaxo ...  -  Apr 6, 2007
Trading Markets,The current leading market players in the treatment of type-2 diabetes are Takeda, which produces Actos, and GlaxoSmithKline, the maker of Avandia.

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,Rosiglitazone (sold as Avandia by Glaxo Smith Kline), and Pioglitazone (sold in the name of Actos by Lilly/Takeda) are the two drugs available in this class

Art vs. global warming /A rose for every book  -  Apr 13, 2007
ABS CBN News,...will share with listeners reflections on news information and television experiences on Thursday, April 19, 7 pm at IC’s Salon de Actos.

Analysis: Merck surges on revised forecast  -  Apr 13, 2007
United Press InternationalHe noted Januvia at 24 weeks post-launch "is tracking at 141 percent of the (Takeda's) Actos ramp and Gardasil generated $114 million in US sales in January

Colombian Contrasts: Bush, Spanish Royalty, literature, kidnapping ...  -  Apr 12, 2007
Global Voices Online,...amigo su victoria cotidiana y personal y la manera en que sacan fuerza para seguir viviendo a pesar de las situaciones adversas o los actos violentos.

Most promising drugs in development for metabolic syndrome  -  Apr 12, 2007
News-Medical.net,...side effects that have limited the market potential of currently available drugs in this class, such as Takeda's Actos and GlaxoSmithKline's Avandia.

Most Promising Emerging Agents for Metabolic Syndrome are from ...  -  Apr 10, 2007
PR-Inside.com (Pressemitteilung),...potential of currently available drugs in this class, such as Takeda's Actos and GlaxoSmithKline's Avandia. Emerging drugs that modulate the incretin

Merck Up on FDA Janumet OK  -  Apr 2, 2007
Forbes,Twenty-three weeks after being on the market, Januvia had about 20600 new prescriptions, 55 percent higher than Takeda Chemical Industries Ltd.'s Actos,

Merck's Janumet, Pill for Diabetes, Approved by US (Update2)  -  Apr 1, 2007
Bloomberg...which is made by more than a dozen generic drugmakers; Eli Lilly & Co.'s Byetta; Takeda Pharmaceutical Co.'s Actos; and GlaxoSmithKline Plc's Avandia.

Attorney's Fees Reimbursement granted in Takeda's Patent case on Actos  -  26 Mar 2007
PharmaLive.com (press release),Mylan Pharmaceuticals 1 and Alphapharm Pty 2 , defending against a challenge to Takeda's patent on ACTOS® (pioglitazone hydrochloride).

Takeda's Actos linked to increased risk of fracture for women  -  Mar 12, 2007
Pharma Times (subscription),The warning comes after an analysis of the drugmaker's clinical trial database for Actos (pioglitazone) which showed more reports of fractures in female

Takeda Warns of Broken Bones in Women Taking Actos for Diabetes  -  Mar 9, 2007
BloombergTakeda decided to study Actos, the world's second-biggest diabetes drug, to see whether there were similar risks, said Jocelyn Gerst, a company spokeswoman.

Pioglitazone (Actos) Increases Limb Fractures in Women  -  Mar 9, 2007
MedPage Today,...informed physicians today of an increased occurrence rate of arm, hand, and foot fractured among women taking pioglitazone (Actos) for type 2 diabetes.

Actos (Pioglitazone) Tablets - Evaluation of Safety Data Showed ...  -  Mar 9, 2007
DG NewsBETHESDA, MD -- March 9, 2007 -- Takeda and FDA notified healthcare professionals of recent safety data concerning pioglitazone-containing products.

Judge Orders Generics to Pay Takeda Legal Fees  -  Mar 21, 2007
Reuters.uk,In February 2006, US District Judge Denise Cote ruled that Takeda's patent on its Actos diabetes drug was valid, a blow to Mylan and Alphapharm,

Mylan, another generic firm ordered to pay Takeda  -  Mar 23, 2007
San Antonio Business Journal,In February 2006, Cote ruled that Takeda's patent on its Actos diabetes drug was valid, but both companies challenged the ruling.

Eisai Pays $325 Million for Morphotek Biotech Company (Update3)  -  Mar 22, 2007
BloombergJapanese drugmakers, which gave the world blockbuster medicines such as Actos for diabetes and the Mevalotin cholesterol reducer, are trying to catch up to

Diabetes drug may pose bone break risk  -  Mar 19, 2007
Sydney Morning Herald,Pharmaceutical company Eli Lilly is writing to doctors in Australia to alert them to new findings for its medication, Actos.

Health Matters: Going out on a limb, exercise can't hurt  -  Mar 14, 2007
Terre Haute Tribune Star,Now comes the news that its sister drug, pioglitazone (Actos), also an insulin sensitizer, carries an increased risk of … arm, hand and foot fractures in

Prevention vs. drugs. The real Conversation on Health  -  Mar 1, 2007
Common Ground.ca,The end of Rezulin became the best kind of marketing opportunity for the drugs that replaced it: Avandia and Actos. The glitazones, as these drugs are

More Fractures in Women on Takeda Diabetes Drug-FDA  -  Mar 11, 2007
Reuters.uk,Pioglitazone is an active ingredient in Actos, Actoplus met and duetact, all sold to treat diabetes. "Healthcare professionals should consider the risk of

Fracture Risk in Pioglitazone-Treated Women  -  Mar 12, 2007
Facts and Comparisons,...advised to consider increased fracture risk when initiating or treating female type 2 diabetes patients with pioglitazone (Actos)-containing products.

Pioglitazone linked to fracture risk in women  -  Mar 9, 2007
TheHeart.Org,Rockville, MD - Pioglitazone (Actos, Takeda Pharmaceuticals North America, Inc) therapy may be linked to an increased risk for fracture in women,

Dr. White Answers Your Medication Questions  -  Mar 24, 2007
Diabetes Interview,These drugs include sulfonylureas, metformin, Actos, Avandia, Byetta, Prandin, Starlix, Precose, Glyset, Januvia, and Galvus. All of these are prescribed to

lIFESTYLE & cULTURE  -  Mar 24, 2007
What's On & Expat,At the Salon de Actos of Instituto Cervantes (855 TM Kalaw Street, 1000 Ermita, Manila), 6 pm. Call (02) 526-1482 to 85.

Cuban Street Dancing Festival in April  -  Mar 23, 2007
Prensa Latina,Workshops by foreign specialists like the Argentina company Actos Alusivos about children´s creation, conferences, exhibitions and master classes are also

Ranbaxy targets $2b US sales from generic brands  -  Mar 14, 2007
Times of India,The block-buster molecules including atorvastatin (lipitor), pioglitazone (actos), valacyclovir (valtrex) and tamsulosin (flomax), are expected to be

Japan Stocks Advance After Yen Weakens, GDP Growth Accelerates  -  Mar 11, 2007
Bloomberg1 drugmaker warned that US doctors found an increased risk of broken bones in women taking its Actos diabetes medicine. Takeda and US regulators urged

Japanese Stocks May Advance After Yen Weakens, Honda May Rise  -  Mar 11, 2007
Bloomberg1 drugmarker warned that US doctors found an increased risk of broken bones in women taking its Actos diabetes medicine. Takeda and US regulators urged

Asian Markets End Positive, As A Fall In US Jobless Data Helps ...  -  Mar 12, 2007
Trading Markets,Takeda Pharmaceutical fell 0.8%, after the company warned that women with type 2 diabetes consuming the company's Actos diabetes medicine are prone to

Pioglitazone Linked to Fracture Risk in Women  -  Mar 9, 2007
Medscape (subscription)Pioglitazone HCl is currently marketed as a single drug (Actos) and in combination with metformin HCl (Actoplus met) or glimepiride (duetact,

For Merck, A New Worry Amid Success  -  Feb 28, 2007
Forbes,In the past several months, studies of Actos and Avandia, from Takeda Pharmaceutical and GlaxoSmithKline (nyse: GSK - news - people ), have failed to

Novartis Says FDA Wants New Galvus Study; Shares Drop (Update9)  -  Feb 26, 2007
BloombergThe delay is positive for competitor Merck as well as GlaxoSmithKline Plc and Takeda Pharmaceutical Co., whose drugs Avandia and Actos will now face less

Pharma Sector: Few Newsmakers Of The Week - Lilly, Novartis ...  -  Mar 5, 2007
Trading Markets,The current leading market players in the treatment of type-2 diabetes are Takeda, which produces Actos, and GlaxoSmithKline, the maker of Avandia.

Takeda Profit Jumps 7.2% on US Sales of Actos (Update1)  -  Jan 30, 2007
BloombergActos, which accounts for a quarter of Takeda's sales, faces competition from newer drugs, including Merck & Co.'s Januvia.

Takeda 9-mth profit climbs 13.6 pct on Actos sales  -  Jan 30, 2007
ReutersT: Quote, Profile, Research), Japan's largest drug maker, posted a strong 13.6 percent rise in nine-month profit on robust sales of its Actos diabetes drug.

Takeda Announces Submission Of Application For Additional ...  -  Jan 28, 2007
Medical News Today (press release),Takeda Pharmaceutical Company Limited announced that today it submitted an application for an additional indication of ACTOS(R) (pioglitazone HCl) with

Lilly Announces 2006 Adjusted EPS of $3.18 Excluding Charges and ...  -  Jan 31, 2007
Drug Newswire (press release),Excluding the impact of lower Actos(R) revenue due to the expiration of Lilly's US marketing rights, worldwide sales for the quarter increased 12 percent.

UPDATE 3-Takeda 9-mth profit up, Daiichi lifts outlook  -  Jan 31, 2007
ReutersT: Quote, NEWS , Research) posted a 14 percent rise in nine-month profit on robust sales of its Actos drug for diabetes, while Daiichi Sankyo Co.

Sales strong for Takeda but pressure to expand is on  -  Feb 1, 2007
Pharma Times (subscription),Strong sales of the diabetes treatment Actos has helped Takeda Pharmaceutical Co, Japan's largest drugmaker, post a 7.3% increase in sales for the nine

Lectures about Local Taxes in Spain  -  Feb 3, 2007
Rundtownnews.co.uk,Salón de Actos. C/.San Antonio 21. 30th Mar. - H. FRAILES - 11am - Centro Social Polivalente. Avda Blasco Ibáñez 10A. 10th Apr. - PINOSO - 6pm - Universidad

Takeda 9-mth profit up, keeps forecasts  -  Jan 30, 2007
Boston Globe,T>, Japan's largest drug maker, posted a strong 13.6 percent rise in nine-month profit on robust sales of its Actos diabetes drug and kept its full-year

Profit Falls at Japan Drug Makers  -  Jan 31, 2007
Wall Street Journal (subscription),Among key products, sales of the diabetes drug Actos, one of Takeda's best-selling drugs, jumped 43% from a year earlier to 253.6 billion yen.

Harvard Fish Study Leads Novartis to Diabetes Drugs (Update5)  -  Feb 6, 2007
BloombergThe older drugs include metformin, sold in generic form by several companies, and Actos, from Lilly and Takeda Pharmaceutical Co. of Osaka, Japan.

FDA Accepts Merck's 2 Supplemental New Drug Applications For Januvia  -  Feb 15, 2007
Trading Markets,The current leading market players in the treatment of type-2 diabetes are Takeda, which produces Actos, and GlaxoSmithKline, the maker of Avandia.

Prague - absolutely fabulous  -  Feb 9, 2007
Sur,On Tuesday, 13th February, at 10.30 am in the Salon de Actos, Mijas Town Hall, there will be an illustrated talk by Mr. John Davies, BA, Dip. Tech.

GlaxoSmithKline Q4 Profit Rises 5.3%; Sees FY07 EPS Growth Of 8% - 10%  -  Feb 8, 2007
Trading Markets,Japan-based Takeda, which produces Actos, is also a leading market player in type-2 diabetes. Merck's Januvia, a DPP-4 inhibitor was approved for the

Moonlight plans summer of classics  -  Feb 7, 2007
North County Times,..."Actos," "La Carpe" and "Los Vendidos," three short plays by Mexican-American playwright Luis Valdez, will be presented by Teatro Mascara Magica,

McGuinty Government Strengthening Diabetes Care  -  Feb 6, 2007
CNW Telbec (Communiqués de presse),...the new drug, Actos, to the province's list of medicines covered by the Ontario Drug Benefit Program under Bill 102's new conditional listing mechanism.

Latino theater coming to Fallbrook  -  Feb 1, 2007
Village News Network,For students, he will offer three performance/workshops on three plays by Luis Valdez (“Actos,� “La Carpe� and “Los Vendidos�) at 10 am, 11 am and 1 pm All

Lilly profit slumps, hurt by Zyprexa charge  -  Jan 31, 2007
KPLC-TV,Diabetes drug Actos had sales of $90 million, a 42 percent decline, due to Lilly' loss in September of US marketing rights to the drug.

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