Recent news on Capecitabine

GlaxoSmithKline Reports Further Progress of Oncology Portfolio  -  25 May 2007
PR Newswire (press release),GSK will make 30 data presentations at ASCO including 18 for TYKERB(R)/TYVERB(TM) (lapatinib), which is approved in the US in combination with capecitabine

Swiss give Glaxo cancer pill first Europe approval  -  May 23, 2007
ReutersThe once-a-day pill is designed for patients with advanced breast cancer in combination with Roche's oral chemotherapy drug, Xeloda, or capecitabine.

Cytokinetics Announces Clinical Trials Data to Be Presented at the ...  -  May 18, 2007
Genetic Engineering News (press release),The clinical trial evaluating ispinesib in combination with capecitabine is ongoing. Final data from this trial are expected in 2007.

Curing Cancer: Running on Vapor  -  May 1, 2007
Genetic Engineering News (press release),The latest treatment with Herceptin followed by lapatinib and capecitabine only increased the median time to progression from 4.4 to 8.4 months.

Roche updates on flu manufacturing; expands US unit  -  Apr 26, 2007
OutSourcing-Pharma.com,It has contributed to the development of manufacturing protocols for a number of Roche's leading brands, including cancer drug Xeloda (capecitabine),

Antisense—down, but not out  -  Apr 30, 2007
Nature.com (subscription),...is combined with the oral chemotherapy drug Xeloda (capecitabine; Roche Laboratories, Nutley, NJ, USA) in phase 2 trials for kidney cancer.

Roche updates on flu manufacturing; expands US unit  -  26 Apr 2007
In-PharmaTechnologist.com,It has contributed to the development of manufacturing protocols for a number of Roche's leading brands, including cancer drug Xeloda (capecitabine),

ADVENTRX announces positive data from multidrug therapy with cofactor  -  Apr 22, 2007
News-Medical.net,An abstract entitled "Antitumor activity and safety of a hybrid treatment regimen of 5,10-methylenetetrahydrofolate, 5-fluorouracil, and capecitabine in a

ADVENTRX Announces Positive Data From Multidrug Therapy With CoFactor  -  Apr 18, 2007
PR-Inside.com (Pressemitteilung),...groups containing leucovorin or capecitabine alone in a colorectal tumor model. An abstract entitled "Antitumor activity and safety of a hybrid treatment

ADVENTRX Announces Positive Data From Multidrug Therapy With CoFactor  -  Apr 18, 2007
Earthtimes.orgTumor-bearing mice treated with CoFactor, 5-FU and capecitabine had the greatest inhibition of tumor growth compared to the other drug regimens tested in

Market Report -- In Play (ANX)  -  Apr 18, 2007
MSN MoneyTreatment with a regimen including CoFactor with 5-fluorouracil and capecitabine (Xeloda), an oral prodrug of 5-FU, demonstrated superior inhibition of

The High Cost of New Cancer Therapies Has Made Them Targets for ...  -  Apr 20, 2007
PharmaLive.com (press release),...or metastatic breast cancer in combination with Xeloda (capecitabine) in women who have received prior therapy, including Herceptin (trastuzumab).

Research and Markets: Ixabepilone is Predicted to Reach the Market ...  -  Apr 18, 2007
PharmaLive.com (press release),...to reach the market in late 2007 for the second-line treatment of patients with metastatic breast cancer in combination with Xeloda (capecitabine).

GSK gets FDA nod for cancer drug  -  Apr 4, 2007
Express Pharma,GlaxoSmithKline received an approval for Tykerb (lapatinib), in combination with Xeloda (capecitabine), for the treatment of patients with advanced or

Roche applies for drug license extensions  -  Apr 17, 2007
newratings.comThe application is for allowing the use of Xeloda (capecitabine) and Xelox (oxaliplatin), with or without Avastin (bevacizumab), for the treatment of

'Well, I'm finally a size eight ... '  -  Mar 28, 2007
Guardian Unlimited,When Omnitarg stopped working, within a matter of months, the doctors switched me on to capecitabine, a standard chemotherapy drug, but one which they hoped

GSK seeks approval for lapatinib for breast cancer patients in Japan  -  Apr 2, 2007
SpiritIndia,The indication for which the company seeks approval is for both monotherapy and for combination treatment with capecitabine for patients with advanced or

Xeloda approved in Europe for the treatment of advanced stomach cancer  -  Apr 2, 2007
WebWire (press release),..."Not only is capecitabine as effective and safe as intravenous treatment but it also reduces the time patients need to spend in hospital by 80%,

‘This drug changed my life’  -  Apr 1, 2007
Times-West Virginian,...which, when combined with the chemotherapy drug Capecitabine, attacks a protein on the cancer cell that makes the disease very aggressive for 25 percent

Glaxo seeks Japan marketing OK for breast cancer pill Tykerb  -  Apr 2, 2007
Forbes,The company is seeking approval as both monotherapy and combination treatment with chemotherapy agent capecitabine for patients with advanced or metastatic

Cytokinetics Announces Non-Clinical Trial Data Presented at 2007 ...  -  Apr 19, 2007
PipelineReview.com (press release),The clinical trial evaluating ispinesib in combination with capecitabine is ongoing. The NCI has sponsored six additional Phase II clinical trials,

AACR: Cetuximab Shows Survival Edge as Third-Line Colorectal ...  -  Apr 17, 2007
MedPage Today,Among patients who failed 5-FU or capecitabine therapy as well as irinotecan and oxaliplatin (Eloxatin), cetuximab on top of best supportive care was

ADVENTRX to Present CoFactor Multiagent Therapy Data at AACR ...  -  Apr 5, 2007
Drug Newswire (press release),The abstract entitled "Antitumor activity and safety of a hybrid treatment regimen of 5,10-methylenetetrahydrofolate, 5-fluorouracil, and capecitabine in a

Roche Submits Application to the FDA for use of XELOX (Xeloda(R ...  -  Apr 5, 2007
Drug Newswire (press release),XELOX is an abbreviation for a type of combination chemotherapy used to treat colorectal cancer; it contains XELODA (capecitabine) plus oxaliplatin.

VioQuest Pharmaceuticals Adds Two New Products to Its Pipeline  -  Mar 30, 2007
PharmaLive.com (press release),Incidence of HFS can be as high as 50% in patients receiving initial chemotherapy with higher dose regimens of capecitabine. The risk of developing HFS

Xeloda Approved in Europe for the Treatment of Advanced Stomach Cancer  -  Mar 29, 2007
Juraforum.de,..."Not only is capecitabine as effective and safe as intravenoustreatment but it also reduces the time patients need to spend inhospital by 80%,

Adherex Announces Two Presentations of ADH-1 Data at 2007 American ...  -  Apr 17, 2007
PharmaLive.com (press release),...began in October 2006, is exploring ADH-1 in combination with three different anti-cancer chemotherapies (docetaxel, carboplatin and capecitabine).

Amgen reschedules plans for Ireland but commitment is still strong  -  Apr 5, 2007
Pharma Times (subscription),...which has just been approved by the US Food and Drug Administration for advanced breast cancer, in combination with Roche's Xeloda (capecitabine).

GSK files in Japan for Tykerb and in Europe for Globorix  -  Apr 2, 2007
Pharma Times (subscription),The drugmaker is seeking the green light for Tykerb (lapatinib) as a monotherapy and in combination with Roche's chemotherapy agent Xeloda (capecitabine),

sNDA Submitted for Xelox  -  Mar 30, 2007
Cancer Consultants (press release),...of Xelox (Xeloda® (capecitabine) plus Eloxatin® (oxaliplatin)) with or without Avastin® (bevacizumab) for the treatment of metastatic colorectal cancer.

Roche's Xeloda approved in EU for advanced stomach cancer  -  Mar 30, 2007
Pharma Times (subscription),The Basel-based firm said that the European Commission has approved Xeloda (capecitabine) treatment in combination with platinum-based chemotherapy,

GlaxoSmithKline to create 150 jobs in Cork over next five years  -  Mar 29, 2007
FinFacts Ireland,...in combination with Xeloda (capecitabine), for the treatment of patients with advanced or metastatic breast cancer whose tumours overexpress HER2 and

OTN's Specialty Pharmacy, ivpcare, Selected to Dispense Newly ...  -  Mar 29, 2007
Drug Newswire (press release),...approved Tykerb on March 13, 2007, for the treatment of advanced or metastatic breast cancer in combination with Xeloda(R) (capecitabine).

ADVENTRX to Present CoFactor Multiagent Therapy Data at AACR ...  -  Mar 29, 2007
Earthtimes.org...announced today that results from preclinical studies of ANX-510 (CoFactor(R)) in combination with intravenous 5-fluorouracil (5-FU) and capecitabine

Avastin approved for metastatic breast cancer in EU  -  Mar 29, 2007
Pharma Times (subscription),...in the first-line treatment of the disease in combination with docetaxel and other commonly used chemotherapies including its own Xeloda (capecitabine).

Update on Tony Snow's Recurrent Colon Cancer  -  Mar 28, 2007
ScienceBlogs...and release of bevacizumab, capecitabine, and oxaliplatin - just to name a few of the advances coming from Big Pharma, bless their capitalist souls.

Vinflunine/Capecitabine Combo Shows Favorable Results in ...  -  Feb 8, 2007
DG NewsPARIS, FRANCE -- February 8, 2007 -- Concurrent use of vinflunine and capecitabine as second-line treatment in patients with metastatic breast cancer is

Solo Capecitabine Shows Good Results in Advanced Breast Cancer ...  -  Feb 6, 2007
DG NewsCapecitabine is an attractive monotherapy in this setting and offers high activity, good tolerability with no alopecia and little myelosuppression,

Oral Cancer Drug Xeloda Receives Positive Opinion from the ...  -  Feb 23, 2007
PharmaLive.com (press release),23, 2007-Roche announced today that its innovative oral cancer drug Xeloda (capecitabine), in combination with platinum-based chemotherapy, has received a

EU panel backs Novartis' mock-up pandemic flu vaccine  -  Feb 23, 2007
MarketWatchXeloda (capecitabine), from Roche Registration Ltd, to extend the indication to include first-line treatment of patients with advanced gastric cancer in

Cytokinetics, Incorporated Reports Fourth Quarter and Year End ...  -  Jan 31, 2007
PR Newswire (press release),The data from this ongoing clinical trial demonstrated that the combination of ispinesib and capecitabine may have an acceptable tolerability profile.

X-rays? Next left, then take the M1  -  Feb 19, 2007
Guardian Unlimited,...plastic bag filled with Herceptin - the drug I am still taking in combination with the huge pink tablets I swallow daily, called capecitabine.

New work programme for NICE announced  -  Feb 8, 2007
Media Newswire (press release),To appraise the clinical and cost effectiveness of lapatinib plus capecitabine within its licensed indications for advanced, metastatic or recurrent breast

Made to feel special  -  Feb 8, 2007
Advertiser 24,With this particular drug (capecitabine), it's fairly unlikely. Don't worry, there is still an impressive list of common side-effects - nausea, vomiting,

SMS Pharma IPO subscribed 1.32 times  -  Feb 8, 2007
Moneycontrol.com,It has started producing ACE Inhibitors like Perindopril Erubamine and Imidapril and anti- cancer drug Capecitabine and Bicalutamide. As per Metro Vision,

New work programme for NICE announced  -  Feb 7, 2007
netPR.pl (komunikaty prasowe),Lapatinib for advanced or metastatic breast cancer To appraise the clinical and cost effectiveness of lapatinib plus capecitabine within its licensed

Roche Posts Outstanding Results for 2006  -  Feb 7, 2007
PharmaLive.com (press release),Xeloda (capecitabine) is an effective oral anticancer therapy that greatly simplifies treatment and also saves costs by reducing the need for hospital

NCCN Updates Colon Cancer Guidelines  -  Jan 29, 2007
PharmaLive.com (press release),The combination regimen CapeOX, which is capecitabine (Xeloda, Roche) and oxaliplatin (Eloxatin, sanofi-aventis), was added as an alternate option to the

Sanofi-aventis 2006: In a Difficult Environment, Another Year of ...  -  Feb 12, 2007
Yahoo! News (press release)...breast cancer progressing after anthracycline/taxane, but did not reach superiority in a phase III study versus capecitabine in the same population.

Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer  -  Dec 27, 2006
New England Journal of Medicine (subscription),Conclusions Lapatinib plus capecitabine is superior to capecitabine alone in women with HER2-positive advanced breast cancer that has progressed after

Adding Lapatinib to Capecitabine Cuts Progression of Advanced ...  -  Dec 28, 2006
Cancerpage.com,NEW YORK DEC 27, 2006 (Reuters Health) - Adding lapatinib to chemotherapy with capecitabine reduces the risk of disease progression in women with

Adding lapatinib to capecitabine cuts progression of advanced ...  -  Dec 27, 2006
Therapeutics Daily (subscription) (press release),NEW YORK (Reuters Health) - Adding lapatinib to chemotherapy with capecitabine reduces the risk of disease progression in women with HER2-positive advanced

Capecitabine Plus Bevacizumab Combination May Produce Clinical ...  -  Dec 20, 2006
DG News...for HER2-Negative Metastatic Breast Cancer) trial suggested that first-line therapy with oral Xeloda(R) (capecitabine) in combination with Avastin(R)

Landmark Tykerb(R) (Lapatinib) Data Published in the New England ...  -  Dec 28, 2006
PR Newswire (press release),Lapatinib combined with capecitabine has demonstrated superior efficacy over capecitabine alone in this group of patients and we look forward to it being

Addition of Tykerb® Improves Progression-Free Survival in Advanced ...  -  Jan 5, 2007
Cancer Consultants (press release),Lapatinib plus Capecitabine Shows Superior Efficacy Compared to Capecitabine Alone in Patients with ErbB2 Positive Advanced or Metastatic Breast Cancer-

Breast Cancer Treatment Drug Tykerb Slows Tumor Growth  -  Dec 28, 2006
eMaxHealth.com,Phase III data reporting that Tykerb plus Xelod is superior to capecitabine alone in women with HER2 (ErbB2) positive advanced breast cancer who had

Adjuvant Therapy for Pancreatic Cancer  -  Jan 16, 2007
Journal of American Medical Association (subscription),Phase III randomised comparison of gemcitabine (GEM) versus gemcitabine plus capecitabine (GEM-CAP) in patients with advanced pancreatic cancer. EJC Suppl.

Addition of Tykerb® Improves Outcomes in Advanced Breast Cancer  -  Jan 3, 2007
Cancer Consultants (press release),According to the results of a study published in the New England Journal of Medicine, the addition of Tykerb® (lapatinib) to Xeloda® (capecitabine) delays

Erbitux® Combinations Evaluated in Rectal and Esophageal Cancer  -  Jan 2, 2007
Cancer Consultants (press release),Cetuximab in combination with capecitabine, oxaliplatin and concomitant radiotherapy (Cet-Capox-RT) as preoperative therapy for rectal cancer.

AUDIO SUMMARY  -  Dec 27, 2006
New England Journal of Medicine (subscription),Featured are articles on decreasing catheter-related bloodstream infections in the ICU, lapatinib plus capecitabine for HER2-positive advanced breast cancer

Cytokinetics Announces Initiation Of Phase II Clinical Trial In ...  -  Dec 24, 2006
Haber Sağlık,The clinical trial evaluating ispinesib in combination with capecitabine is ongoing. The NCI has sponsored five additional Phase II clinical trials

Drug Reformulation: It’s Not Just About Patent Protection  -  Jan 15, 2007
Drug Discovery & Development,..."I was dying to put her on oral chemotherapy with capecitabine, but she couldn't swallow the pills, and there wasn't another formula, so she's now on an IV

Abraxane in Combination with Xeloda Effective Against Metastatic ...  -  Jan 3, 2007
Cancer Consultants (press release),Phase II trial of nanoparticle albumin-bound paclitaxel (ABX) + capecitabine (XEL) in first line treatment of metastatic breast cancer (MBC): interim

Safe Practice Guidelines for Oral Chemotherapy Found Gravely Lacking  -  Jan 12, 2007
MedPage Today,The drugs included Xeloda (capecitabine), Cytoxan (cyclophosphamide), Iressa (gefitinib), Gleevec (imatinib), oral Rheumatrex (oral methotrexate),

Cetuximab (Erbitux®) Combinations Evaluated in Rectal and ...  -  Jan 2, 2007
Cancer Consultants (press release),Researchers from Germany presented data on a phase I/II study of cetuximab, Xeloda® (capecitabine) and Eloxatin® (oxaliplatin) and concomitant radiotherapy

Abraxane® in Combinaton with Xeloda® Effective Against Metastatic ...  -  Jan 2, 2007
Cancer Consultants (press release),Phase II trial of nanoparticle albumin-bound paclitaxel (ABX) + capecitabine (XEL) in first-line treatment of metastatic breast cancer (MBC): interim

Tykerb Plus Chemotherapy Slows Advance of Metastatic Breast Cancer  -  Dec 28, 2006
MedPage Today,...advanced-stage breast cancer, the time to disease progression may be doubled by adding Tykerb (lapatinib) to Xeloda (capecitabine) chemotherapy,

Xeloda(R) Combination Meets Primary Endpoint In International ...  -  Dec 24, 2006
Medical News Today (press release),XELOX is an abbreviation for a type of combination chemotherapy used to treat colorectal cancer; it contains Xeloda (capecitabine) plus oxaliplatin.

Cytokinetics Announces Non-Clinical Poster Presentation Regarding ...  -  26 Dec 2006
PR Newswire (press release),...anti-cancer therapeutic, one in combination with carboplatin, the second in combination with capecitabine, and the third in combination with docetaxel.

Capecitabine Plus Bevacizumab Combination May Produce Clinical ...  -  Dec 20, 2006
DG News...for HER2-Negative Metastatic Breast Cancer) trial suggested that first-line therapy with oral Xeloda(R) (capecitabine) in combination with Avastin(R)

Older Women With Breast Cancer Respond to Treatment With ...  -  Dec 18, 2006
DG NewsThe researchers treated these women with capecitabine 1000 mg/m 2 daily on days 1 through 14, in addition to vinorelbine 25 mg/m 2 on days 1 and 8,

Lapatinib Added to Capecitabine Improves Progression-Free Survival ...  -  Dec 15, 2006
DG NewsPatients are randomized to receive lapatinib 1250 mg once daily with capecitabine, 2000 mg/m 2 /day on days 1-14, every 21 days or monotherapy with

Cytokinetics Announces Initiation Of Phase II Clinical Trial In ...  -  Dec 24, 2006
Haber Sağlık,The clinical trial evaluating ispinesib in combination with capecitabine is ongoing. The NCI has sponsored five additional Phase II clinical trials

Sonogram Results Can Help Direct Additional Treatment in Women ...  -  Dec 19, 2006
DG NewsThe 627 low chemosensitive women went on to receive an additional 4 cycles of TAC or 4 cycles of vinorelbine/capecitabine while the 1390 highly

Another bitter pill  -  Dec 14, 2006
Guardian Unlimited,Hence the Capecitabine, not a trial drug at all, but an older, rougher form of chemotherapy. Capecitabine is a tablet, though, rather than a plastic bag

Cytokinetics and GlaxoSmithKline Amend Collaboration and License ...  -  Nov 27, 2006
Earthtimes.orgDose limiting toxicities observed included Grade 2 rash that did not allow 75% of the capecitabine doses to be delivered and prolonged Grade 4 neutropenia.

Clinical Trials Update: Dec. 15, 2006  -  Dec 15, 2006
Austin American-Statesman (subscription),This clinical study will compare the effectiveness of an investigational product versus capecitabine in people with advanced or metastatic pancreatic cancer

New research from Yale University, US, described.  -  Dec 7, 2006
Therapeutics Daily (subscription) (press release),According to recent research from the United States, "Peripheral neuropathy secondary to 5-flourouracil and capecitabine (Xeloda) has been reported.

Cytokinetics Amends Deal With GlaxoSmithKline; Trims FY06 Revenue ...  -  Nov 27, 2006
Trading Markets,The company is also mulling over the combination treatment approach of Ispinesib with Capecitabine in treating breast cancer.

Xeloda(R) Combination Meets Primary Endpoint In International ...  -  Dec 24, 2006
Medical News Today (press release),XELOX is an abbreviation for a type of combination chemotherapy used to treat colorectal cancer; it contains Xeloda (capecitabine) plus oxaliplatin.

SABCS: Abraxane Combination Therapy Effective for Metastatic ...  -  Dec 18, 2006
MedPage Today,...the nanoparticle albumin-bound form of paclitaxel, appears effective against metastatic breast cancer in combination with Xeloda (capecitabine),

Lapatinib (Tykerb (Reg)) To Be Evaluated In Early Stage Disease In ...  -  Dec 16, 2006
Medical News Today (press release),In a phase III study of Tykerb in combination with capecitabine in patients who have progressed on Herceptin treatment was stopped early by an Independent

Xeloda(R) Plus Avastin(R) Combination May Produce Clinical Benefit ...  -  Dec 15, 2006
Yahoo! News (press release)First-Line Treatment for HER2-Negative Metastatic Breast Cancer) trial suggested that first-line therapy with oral Xeloda® (capecitabine) in combination

Xeloda meets primary endpoint in multinational Phase III advanced ...  -  Dec 12, 2006
PipelineReview.com (press release),An abbreviation for a type of combination chemotherapy used to treat colorectal cancer; it contains Xeloda (capecitabine) plus oxaliplatin.

Abraxis BioScience to present data from six studies at San Antonio ...  -  Dec 11, 2006
CNW Telbec (Communiqués de presse),5:00 pm-7:00 pm Phase II trial of nanoparticle albumin-bound paclitaxel (ABX) + capecitabine (Xel) as first line treatment of metastatic breast cancer

Xeloda Meets Primary Endpoint in Multinational Phase III Advanced ...  -  Dec 10, 2006
Earthtimes.orgAn abbreviation for a type of combination chemotherapy used to treatcolorectal cancer; it contains Xeloda (capecitabine) plus oxaliplatin.

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