Recent news on Cisplatin

AUA 2007 Plenary Session: SIU Lecture “What is New in the ...  -  25 May 2007
UroToday,Gemcitabine with cisplatin is less toxic with a similar response rate to MVAC. Paclitaxel with carboplatin for regionally advanced disease showed 5 year

Cisplatin-Sensitive Breast Tumors My Be Identified By Molecular ...  -  Apr 25, 2007
Medical News Today (press release),They also have discovered the molecular basis of this sensitivity, which may help identify patients most likely to benefit from cisplatin treatment.

A Fatal Chemotherapy Error in Canada  -  May 9, 2007
ScienceBlogsBased on the results of an American clinical trial the standard treatment in North America is to give concurrent radiation therapy and cisplatin

NCCN Updates Esophageal and Gastric Cancer Guidelines  -  May 22, 2007
Business Wire (press release),...found that Capecitabine may replace 5-FU and Oxaliplatin may replace Cisplatin in triplet regimens used for the treatment of advanced esophageal and

Post-Op Regimen Ineffective For Advanced Gastric Cancer  -  May 1, 2007
Cancerpage.com,Considering these results, continued Dr. Cascinu, along with data from a trial of preoperative treatment with epidoxorubicin, cisplatin and 5-fluorouracil

Asbestos sufferers denied drugs to ease pain  -  May 10, 2007
Portsmouth News,Alimta is combined with chemotherapy drug Cisplatin to treat the asbestos-related cancer mesothelioma, common among former Portsmouth dockyard workers,

Nano-Pharmaceuticals – Future Cure-All  -  May 3, 2007
Russia-InfoCenter,Two anti-tumor agents Cisplatin and Pluorouracil are in clinical trials, as well as three more drugs with anti-hemorrhagic, wound-healing and

Deadly Cancers Dealt A Knockout Punch  -  May 14, 2007
Medical News Today (press release),In one study, investigators examined the tumor-killing ability of reovirus plus cisplatin, a standard chemotherapy agent, in a mouse melanoma model that

Oncolytics Biotech Inc. Announces 2007 First Quarter Results  -  Apr 27, 2007
Earthtimes.orgThe results of the preclinical study showed that the combination of reovirus and cisplatin was significantly more effective than cisplatin or reovirus alone

AUA 2007 - SUO Session: Transitional Cell Carcinoma I, Optimizing ...  -  May 20, 2007
UroToday,He was concerned that neoadjuvant trials used MVAC and presently gemcitobine/cisplatin is being used. He pointed out that 22 patients would need to get it

Navarra spin-out signs drug deal to develop Hepatitis C treatment  -  May 4, 2007
Science Business (subscription),...oxaliplatin, paclitaxel, cisplatin, and bevacizumab (Avastin®). Results show that DAVANAT® exhibits a broad spectrum of activity with tested drugs.

Point Therapeutics Announces Interim Analysis to be Performed on ...  -  May 15, 2007
PharmaLive.com (press release),In addition, Point has studied talabostat in several Phase 2 trials, including as a single-agent in metastatic melanoma, in combination with cisplatin in

Potency Of Platinum Chemotherapy Dramatically Boosted By Diabetes Drug  -  May 11, 2007
Medical News Today (press release),...combining each of them with cisplatin, carboplatin and oxalyplatin -- all commonly used chemotherapy drugs that destroy cancer cells by damaging their

Point Therapeutics Reports First Quarter 2007 Financial Results  -  May 10, 2007
Genetic Engineering News (press release),...metastatic melanoma, in combination with cisplatin in metastatic melanoma, and in combination with rituximab in advanced chronic lymphocytic leukemia.

Human error led to cancer patient's death  -  May 9, 2007
Globe and Mail,...a drug used to treat tumours, over four hours instead of the prescribed four days, along with another chemotherapy drug, cisplatin.

Human Error And Fatal Chemo Doses  -  May 9, 2007
Medical News Today,She was given an electronic pump containing a four day dose of two chemotherapy drugs, 5-fluorouracil and cisplatin, to administer to herself at home.

Human Error Kills Cancer Patient  -  May 9, 2007
Dog Flu Diet and Diseases,The drugs that were administered to Melanson were fluorouracil which is a drug used to treat tumors, and cisplatin which is a chemotherapy drug.

At least seven cancer patients have died of accidental overdoses ...  -  May 8, 2007
Vancouver Sun (subscription),The report says that in an eighth incident, the patient didn't receive a complete dose of a drug called cisplatin and survived.

Patients Given Monoclonal Antibodies Experience Magnesium Loss  -  May 4, 2007
Medical News Today (press release),...will also be important in those patients receiving combination treatments with nephrotoxic and potential magnesium-wasting agents, such as cisplatin."

Student scientist earns Fulbright Scholarship  -  May 3, 2007
Jewish Review,STS (sodium thiosulfate) to protect against the high frequency hearing loss that usually occurs in children treated with the anti-cancer drug cisplatin.

Coley Pharmaceutical Group Reports First Quarter Financial Results  -  May 3, 2007
PR Newswire (press release),...safety and efficacy of PF-3512676 administered in combination with standard-of-care chemotherapy, gemcitabine/cisplatin, compared to chemotherapy alone,

Magnesium Loss In Patients Given Monoclonal Antibodies  -  May 2, 2007
innovations report,...will also be important in those patients receiving combination treatments with nephrotoxic and potential magnesium-wasting agents, such as cisplatin.�

EGFR-Targeted Therapies for Colorectal Cancer Linked to Lower ...  -  May 1, 2007
MedPage Today,Patients who receive combination treatments that are nephrotoxic and potentially magnesium-wasting, such as cisplatin, require special attention,

Pro-Pharmaceuticals And Digna Biotech Sign Agreement To Apply  -  May 1, 2007
Chemical Online.com (press release),...derivatives of marketed chemotherapeutics and biologics, including doxorubicin, irinotecan, oxaliplatin, cisplatin, paclitaxel, and bevacizumab.

Nanoparticle Treatment Being Tested on Stage 4 Lung Cancer Patients  -  Apr 25, 2007
AZoNano.com,All patients on the trial had been treated with front line cisplatin combination chemotherapy, which failed to halt their disease.

OSI Pharmaceuticals Announces Pivotal Phase III Tarceva Study ...  -  Apr 25, 2007
PharmaLive.com (press release),...with doublet platinum-based chemotherapy (carboplatin and paclitaxel or gemcitabine and cisplatin) and its use is not recommended in that setting.

Cisplatin-Sensitive Breast Tumors My Be Identified By Molecular ...  -  26 Apr 2007
Medical News Today (press release),They also have discovered the molecular basis of this sensitivity, which may help identify patients most likely to benefit from cisplatin treatment.

SciClone Acquires Clinical-Stage Pancreatic Cancer Compound  -  26 Apr 2007
WM Experts (press release),In a separate phase 1 study published in the Journal of Clinical Oncology, patients treated with RP101, gemcitabine and cisplatin had a median survival of

Nanoparticle Treatment Being Tested on Stage 4 Lung Cancer Patients  -  26 Apr 2007
AZoNano.com,All patients on the trial had been treated with front line cisplatin combination chemotherapy, which failed to halt their disease.

OSI Pharmaceuticals Announces Pivotal Phase III Tarceva(R) Study ...  -  26 Apr 2007
Business Wire (press release),...with doublet platinum-based chemotherapy (carboplatin and paclitaxel or gemcitabine and cisplatin) and its use is not recommended in that setting.

Molecular Signature May Identify Cisplatin-sensitive Breast Tumors  -  Apr 22, 2007
Medical News Today (press release),They also have discovered the molecular basis of this sensitivity, which may help identify patients most likely to benefit from cisplatin treatment.

Researchers Have Identified Subgroup Sensitive to the Drug Cisplatin  -  Apr 22, 2007
MedIndia,Researchers have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast

Why cisplatin kills breast cancer cells when other drugs fail  -  Apr 21, 2007
SpiritIndia,Importantly, the chemotherapeutic drug cisplatin, but not other commonly used chemotherapeutic drugs, was found to release TAp73 from delta-Np63,

Viventia Biotech announces results of Proxinium antibody in ...  -  Apr 22, 2007
News-Medical.net,The combination of Proxinium with cisplatin, carboplatin, paclitaxel, 5-fluorouracil, and docetaxel resulted in a significant additive cytotoxic effect (p

Spectrum Pharmaceuticals Announces Data From Three Oncology ...  -  Apr 20, 2007
Medical News Today (press release),In preclinical studies, satraplatin was active in a number of various tumor models and in cells resistant to cisplatin, carboplatin and oxaliplatin.

Spectrum Pharmaceuticals Announces Data From Three Oncology ...  -  Apr 19, 2007
PR Newswire (press release),The present study was conducted to evaluate the effect of SPI (IRL)-1620 on the efficacy of cyclophosphamide and cisplatin in ovarian tumor bearing athymic

Combination Nedaplatin/Radiation Therapy Shown Safe and Effective ...  -  Apr 20, 2007
DG NewsLOS ANGELES, CA -- April 20, 2007 -- A small study has confirmed the efficacy of using nedaplatin, a cisplatin analogue, together with radiotherapy in women

ChemGenex Reports Preclinical Data at American Association of ...  -  Apr 16, 2007
Genetic Engineering News (press release),This data further support the potential for CXS299 as a therapeutic agent for patients who have inherent resistance or who develop resistance to cisplatin.

Clinical Trials Update: April 19, 2007  -  Apr 19, 2007
Atlanta Journal Constitution (subscription),...an investigational drug, vinflunine, in combination with gemcitabine in patients with transitional cell carcinoma who cannot be treated with cisplatin.

Xeloda Approved in Europe for the Treatment of Advanced Stomach Cancer  -  Mar 29, 2007
campus med,The study compared the efficacy and safety of Xeloda and cisplatin (XP) with intravenous (iv) 5-FU and cisplatin (FP): FP is a standard treatment of stomach

Xeloda Approved in Europe for the Treatment of Advanced Stomach Cancer  -  Mar 29, 2007
Juraforum.de,The study compared the efficacy and safety of Xeloda andcisplatin (XP) with intravenous (iv) 5-FU and cisplatin (FP): FP isa standard treatment of stomach

More Chemotherapy Not Beneficial in Gastric Cancer  -  Apr 23, 2007
Cancer Consultants (press release),Results from a previous study indicated that the weekly chemotherapy regimen consisting of the chemotherapy agents 5-fluorouracil, epidoxorubicin, cisplatin

Occult Testicular Teratoma Presenting With Solid Mesenteric Metastasis  -  Apr 25, 2007
Journal of Ultrasound in Medicine (subscription)The patient received adjuvant chemotherapy including bleomycin, etoposide, and cisplatin. On follow-up, he was free of recurrence or distant metastasis for

Sequential Chemotherapy Helpful in Advanced Lung Cancer  -  Mar 29, 2007
Cancerpage.com,NEW YORK MAR 29, 2007 (Reuters Health) - In the absence of new therapies, sequential cisplatin-based treatment appears to be a useful option in patients

Erbitux Increases Overall Survival For Head And Neck Cancer Patients  -  Apr 7, 2007
Medical News Today,Half were given Erbitux in combination with cisplatin plus 5-fluorouracil (5-FU) or carboplatin plus 5-FU, while the other half were treated with cisplatin

ImClone, Bristol-Myers Say Erbitux Meets Endpoint  -  Apr 4, 2007
Reuters.uk,The randomized, multi-center study, known as Extreme, studied more than 400 patients treated with Erbitux in combination either with cisplatin plus

Study of Erbitux for Advanced Head and Neck Cancer  -  Apr 4, 2007
SpiritIndia,The randomized, multi-center study, known as EXTREME, studied more than 400 patients treated with ERBITUX in combination either with cisplatin plus

Erbitux hits primary endpoint in head and neck cancer trial  -  Apr 4, 2007
Pharma Times (subscription),The randomised, multi-centre study, called Extreme, analysed more than 400 patients treated in Europe with Erbitux in combination either with cisplatin plus

Viventia biotech reports synergistic effect of its Proxinium(TM ...  -  Apr 18, 2007
CNW Telbec (Communiqués de presse),The combination of Proxinium(TM) with cisplatin, carboplatin, paclitaxel, 5-fluorouracil, and docetaxel resulted in a significant additive cytotoxic effect

Roche's Xeloda Approved in Europe for Stomach Cancer  -  Mar 30, 2007
Reuters.uk,One trial showed that patients given a combination of Xeloda and another chemotherapy, cisplatin, lived at least as long without cancer progressing as those

APS: Xeloda Approved in Europe for the Treatment of Advanced .....  -  Mar 29, 2007
ANP Pers Support,...longer than the reference 5-FU arm (ECF - epirubicin, cisplatin and 5-FU). colorectal cancer that has spread and post-surgery colon cancer.

Randomized Phase III Trial Showed ERBITUX Significantly Improved ...  -  Apr 17, 2007
PipelineReview.com (press release),The safety of ERBITUX in combination with radiation therapy and cisplatin has not been established. Death and serious cardiotoxicity were observed in a

Lilly Oncology Focused on Pharmacogenomics at AACR Annual Meeting  -  Apr 17, 2007
Drug Newswire (press release),The most common adverse events (grades 3/4) with ALIMTA in combination with cisplatin for the treatment of patients with MPM were neutropenia (24%);

Access Pharmaceuticals Announces Poster Presentations on ProLindac ...  -  Apr 16, 2007
PharmaLive.com (press release),The first poster is entitled "Antiproliferative effects of ProLindac, a novel DACH-platinum linked polymer-compound, compared to oxaliplatin and cisplatin

Lilly Oncology focused on pharmacogenomic at AACR meeting  -  Apr 15, 2007
Antara (press release),The most common adverse events (grades 3/4) with ALIMTA in combination with cisplatin for the treatment of patients with MPM were neutropenia (24 per cent);

Merck KGaA: Erbitux Meets Primary Endpoint in First-Line Phase III ...  -  Apr 4, 2007
PipelineReview.com (press release),...cisplatin plus 5-fluorouracil (5-FU) or carboplatin plus 5-FU compared with patients treated with cisplatin plus 5-FU or carboplatin plus 5-FU alone.

Intense Chemotherapy Fails for Gastric Cancer  -  Apr 20, 2007
MedPage Today,About half the patients received eight weekly administrations of cisplatin (40 mg/m 2 ), leucovorin (250 mg/m 2 ), epidoxoorubicin (35 mg/m 2 )

Spectrum Pharmaceuticals (SPPI) Announces Data From Three Oncology ...  -  Apr 19, 2007
StreetInsider.com (subscription),Also, the company announces SPI (IRL)-1620 enhances efficacy of radiation, cisplatin and cyclophosphamide in eexperimental models.

New gene therapy for Stage 4 lung cancer  -  Apr 18, 2007
United Press International...a nanoparticle-based therapy to successfully treat 13 patients whose lung cancer had progressed through first-line cisplatin combination chemotherapy.

Pharmacyclics Identifies Functional Biomarkers for its Novel HDAC ...  -  Apr 18, 2007
PharmaLive.com (press release),...such as gamma- irradiation, cisplatin, and oxaliplatin, and show the usefulness of using RAD51, an enzyme, as a biomarker to predict clinical efficacy.

Intravenous nanoparticle gene therapy shows activity in stage IV ...  -  Apr 18, 2007
Cancer Focus,All patients on the trial had been treated with front line cisplatin combination chemotherapyterm, which failed to halt their disease.

Pro-Pharmaceuticals Issues Corporate Update  -  Apr 17, 2007
PharmaLive.com (press release),...oxaliplatin, paclitaxel, cisplatin, and bevacizumab (Avastin(R)). Results show that DAVANAT(R) exhibits a broad spectrum of activity with tested drugs.

Pro-Pharmaceuticals Issues Corporate Update  -  Apr 17, 2007
Business Wire (press release),...oxaliplatin, paclitaxel, cisplatin, and bevacizumab (Avastin ® ). Results show that DAVANAT ® exhibits a broad spectrum of activity with tested drugs.

Point Therapeutics Announces Preclinical Data Presentations at ...  -  Apr 13, 2007
PharmaLive.com (press release),Point has also studied talabostat in several Phase 2 trials, including as a single-agent in metastatic melanoma, in combination with cisplatin in metastatic

Nicotine supplements can protect cancer cells  -  Apr 13, 2007
Baku Sun,...the effects of nicotine on lung cancer cells that were treated with three commonly used drugs in cancer therapy - gemcitabine, cisplatin and taxol.

Spectrum Pharmaceuticals Announces Three Presentations at 2007 ...  -  Apr 12, 2007
PR-Inside.com (Pressemitteilung),Number: 4058 Presentation Title: ETB Receptor Agonist, IRL-1620, Enhances The Efficacy Of Cyclophosphamide And Cisplatin In Ovarian Tumor Bearing Mice.

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