Recent news on Clodronate

Clodronate Does Not Improve Survival For Prostate Cancer Patients  -  May 19, 2007
Medical News Today (press release),Treatment with the drug clodronate does not improve overall survival for men with localized prostate cancer or delay the disease's progression to metastatic

Bisphosphonate-associated necrosis of the jaws  -  Mar 28, 2007
Woman Dentist Journal,Bisphosphonates that are administered by IV include pamidronate (Aredia), clodronate (Bonefos), and zolendronic acid (Zometa).

Lower Dosing Regimens Of Bisphosphonates Show Antitumor Effects In ...  -  25 Feb 2007
Medical News Today (press release),...tested two types of bisphosphonates - clodronate and zoledronic acid - for their effectiveness at preventing and treating skeletal tumors in mice.

Lower Dosing Regimens Of Bisphosphonates Show Antitumor Effects In ...  -  Feb 22, 2007
Science Daily (press release)...and her colleagues tested two types of bisphosphonates—clodronate and zoledronic acid—for their effectiveness at preventing and treating skeletal tumors

Macrophage Depletion Impairs Wound Healing and Increases Left ...  -  Feb 23, 2007
Am J Pathology (subscription)Infiltrating macrophages were depleted during the 1st week after cryoinjury by serial intravenous injections of clodronate-containing liposomes.

Alendronate Improves Screw Fixation in Osteoporotic Bone  -  Jan 2, 2007
Journal of Bone and Joint Surgery (subscription)Koivukangas A, Tuukkanen J, Kippo K, Jamsa T, Hannuniemi R, Pasanen I, Vaananen K, Jalovaara P. Long-term administration of clodronate does not prevent

In CD4 + T-Cell-Induced Diabetes, Macrophages Are the Final ...  -  Dec 5, 2006
Am J Pathology (subscription)In contrast, in vivo depletion of phagocytic cells by injection of liposomes containing clodronate abolished diabetes, although inflammation remained

Oral Ibandronate Offers Palliative Befits to Patients Who Progress ...  -  Dec 19, 2006
DG NewsDr. Clemons said that in Canada, the most commonly used bisphosphonates are oral clodronate and intravenous pamidronate, with therapy typically maintained

Patients with Breast Cancer Bone Metastasis Failing Bonefos® or ...  Oct 31, 2006
...control in patients with breast cancer who have worsening of bone metastases during bisphosphonate therapy with Aredia® (pamidronate) or Bonefos® (clodronate ... -Cancer Consultants (press release), Second-line Treatment with Zometa® Improves Symptoms in Patients ...  Oct 26, 2006
...cancer patients who experience a worsening of bone metastases during bisphosphonate therapy with Aredia® (pamidronate) or Bonefos® (clodronate), switching to ... -Cancer Consultants (press release), In CD4 + T-Cell-Induced Diabetes, Macrophages Are the Final ...  -  12 Dec 2006
Am J Pathology (subscription)In contrast, in vivo depletion of phagocytic cells by injection of liposomes containing clodronate abolished diabetes, although inflammation remained

Nanoparticle-Drug Combo Stops Tumor-Associated Angiogenesis  Aug 12, 2006
Reto Schwendener, Ph.D., and colleagues developed a liposomal formulation of the drug clodronate to target tumor-associated macrophages, immune system cells ... -Nanotechwire.com

COMBINING BISPHOSPHONATES WITH RALOXIFENE TO TREAT OSTEOPOROSIS: A ...  Aug 21, 2006
...reviewed. Two trials evaluated alendronate or clodronate plus raloxifene for the treatment of osteoporosis in postmenopausal women. ... -The Journal of Pharmacy Technology

Berlex Bonefos For Breast Cancer Bone Metastases Set For Cmte. ...  Jun 30, 2006
The Bonefos (clodronate) NDA (21-776) is receiving a priority review as an adjuvant oral treatment for the reduction of occurrence of bone metastases in Stage ... -Cancer Consultants



Update in Environmental and Occupational Medicine 2005  May 2, 2006
Either the selective depletion of lung macrophages (by intratracheal administration of clodronate liposomes) or the depletion of circulating monocytes and ... - AJRCCM (subscription)





Clodronate® in Early Breast Cancer May Reduce Risk of Developing ...  Mar 21, 2006
Bisphosphonates, such as Clodronate, have been beneficial in patients with cancer that has already spread to the bone and have effectively reduced fractures ... - Cancer Consultants

New Study Shows Reduction in Bone Metastases for Patients Taking ...  Mar 26, 2006
According to recent trial findings, Bonefos(R) (oral clodronate) plus standard adjuvant therapy in primary breast cancer is associated with both reduced bone ... - PR Newswire UK

(PRN) - Innovative Technologies to Promote Enhanced Productivity ...  Mar 26, 2006
China ... [+. PRN) - New Study Shows Reduction in Bone Metastases for Patients Taking Oral Clodronate (BONEFOS(R)) ... PRN ... - Bolsamania.com

Hypoxia-Induced Pulmonary Vascular Remodeling Requires Recruitment ...  Feb 14, 2006
Selective depletion of this monocytic cell population, using either clodronate-liposomes or gadolinium chloride, prevented pulmonary adventitial remodeling (ie ... - Am J Pathology (subscription)

This site is for informational purposes only--it does not offer medical advice or sell health products. If you need assistance, contact your physician or healthcare professional