Recent news on Clozaril

APA: Research Sheds Light on Actions of Atypical Antipsychotics  -  May 22, 2007
MedPage Today,He gave the example of clozapine (Clozaril), a highly efficacious drug for schizophrenia. The drug actually has a low affinity for the dopamine receptor,

APA: Dosing Schedule Doesn't Matter for Antipsychotic Drug Adherence  -  May 21, 2007
Psychiatric Times,...during fiscal year 2005, had been on haloperidol or an atypical antipsychotic, excluding clozapine (Clozaril), with no change in dosing schedule.

Teen Use Of Diabetes Drug Triples In 5 Years  -  May 17, 2007
TheDenverChannel.com,Widely used antipsychotic drugs - including Risperdal, Zyprexa, Seroquel and Clozaril - are approved for treating schizophrenia and bipolar disorder in

Study: Diabetes Drug Use Spikes in Girls  -  May 17, 2007
Wyoming News,Widely used antipsychotic drugs _ including Risperdal, Zyprexa, Seroquel and Clozaril _ are approved for treating schizophrenia and bipolar disorder in

Study: Diabetes Drug Use Spikes in Girls  -  May 16, 2007
Philadelphia Daily News,Widely used antipsychotic drugs , including Risperdal, Zyprexa, Seroquel and Clozaril , are approved for treating schizophrenia and bipolar disorder in

Study: Diabetes drug use spikes in girls  -  May 16, 2007
USA TodayWidely used anti-psychotic drugs — including Risperdal, Zyprexa, Seroquel and Clozaril — are approved for treating schizophrenia and bipolar disorder in

Study: Diabetes Drug Use Spikes In Girls  -  May 16, 2007
Today's THV,Widely used antipsychotic drugs, including Risperdal, Zyprexa, Seroquel and Clozaril, are approved for treating schizophrenia and bipolar disorder in adults

Diabetes Drug Use Spikes in Girls  -  May 16, 2007
Sci-Tech TodayWidely used antipsychotic drugs -- including Risperdal, Zyprexa, Seroquel and Clozaril -- are approved for treating schizophrenia and bipolar disorder in

Study: Diabetes drug use spikes in girls  -  May 16, 2007
Denver Post,Widely used antipsychotic drugs—including Risperdal, Zyprexa, Seroquel and Clozaril—are approved for treating schizophrenia and bipolar disorder in adults,

Amarin Reports First Quarter 2007 Results  -  May 10, 2007
PharmaLive.com (press release),At Alamo, he created a fully integrated commercial pharmaceutical company to market Fazaclo, a reformulation of Novartis' anti-psychotic drug, Clozaril.

Drug Safety Proposals and the Intrusion Of Federal Regulation into ...  -  May 11, 2007
American Enterprise Institute,...in the clinical program and can be mitigated through monitoring and timely intervention (discontinuation) (examples: Trovan, Lotrenox, and Clozaril).[6]

Further research different phases local health kits.  -  Apr 26, 2007
Journal lycéen,Review of reports that Maxzide virus detection antibody tests wave. Neurons are used according K-Dur has no made it Clozaril doubled.

USPSYCH: New Definitions on Tap for Mixed Manias  -  Apr 26, 2007
Psychiatric Times,...risperidone (Risperdal) or ziprasidone (Geodon) as initial treatment with olanzapine (Zyprexa) and clozapine (Clozaril) as alternate choices.

US PSYCH: Vigilance Still Necessary for Atypical Antipsychotics  -  Apr 26, 2007
Psychiatric Times,Clozapine (Clozaril) and olanzapine (Zyprexa) have the highest receptor affinity with quetiapine (Seroquel) and risperidone (Risperdal) in the middle and

Medication Access and Continuity: The Experiences of Dual-Eligible ...  -  May 2, 2007
Am J Psychiatry (subscription)Kluznik JC, Walbek NH, Farnsworth MG, Melstrom K: Clinical effects of a randomized switch of patients from Clozaril to generic clozapine.

USPSYCH: New Definitions on Tap for Mixed Manias  -  26 Apr 2007
Psychiatric Times,...risperidone (Risperdal) or ziprasidone (Geodon) as initial treatment with olanzapine (Zyprexa) and clozapine (Clozaril) as alternate choices.

US PSYCH: Vigilance Still Necessary for Atypical Antipsychotics  -  26 Apr 2007
Psychiatric Times,Clozapine (Clozaril) and olanzapine (Zyprexa) have the highest receptor affinity with quetiapine (Seroquel) and risperidone (Risperdal) in the middle and

Lawsuits filed over fatal overdose  -  Apr 16, 2007
Fresno Bee (subscription),13 and 14 Gremminger was given 300 milligrams of Clozaril. Spitz wrote that the combination of both drugs was dangerous. The doses were given despite a note

Amarin Appoints Paul F. Duffy to New Position of President - US ...  -  Apr 5, 2007
Drug Newswire (press release),At Alamo, he created a fully integrated commercial pharmaceutical company to market Fazaclo, a reformulation of Novartis' anti-psychotic drug, Clozaril.

US researchers link Clozaril, Risperdal, and Zypexa to weight gain ...  -  Mar 8, 2007
iTWire,Clozapine (Clozaril), olanzapine (Zyprexa), and risperidone (Risperdal) are atypical antipsychotic drugs used to control psychotic behavior in humans.

Clozapine Case Series  -  Feb 28, 2007
Psychosomatics (subscription)A 64-year-old woman who carried the diagnosis of schizophrenia had been maintained on clozapine (Clozaril) 125 mg bid, which had been effective in treating

Drugs not enough for mentally ill, study finds  -  Mar 1, 2007
News & Observer,She said her daughter, Kristen, started and stopped about five medicines before finding Clozaril about 10 years ago. It was one of the first "next

Antipsychotic drugs pose risk for elderly dementia patients  -  Feb 26, 2007
Globe and Mail,A fourth in this class, clozapine (Clozaril), was not studied. But because it is in the same family, Health Canada included it in its warning about the

Drug Effects: Do Test Results Correlate With Clinical Gains?  -  Feb 26, 2007
Psychiatric Times,In a separate study with olanzapine (Zyprexa) and clozapine (Clozaril), researchers in Germany sought to determine whether changes in executive function are

They worked my son to death, claims grieving dad  -  Feb 20, 2007
Sunshine Coast Daily,His devastated father, John, believes the death is linked to Clozaril, one of the medications Jon was taking to control his schizophrenia.

Hopkins scientists uncover cause of antipsychotic drug weight gain  -  Feb 13, 2007
Pharmaceutical Business ReviewSuspecting that antipsychotic drugs might spike AMPK in the brain to overact, the Johns Hopkins team injected mice with Clozaril, which, with Zyprexa and

Antipsychotic Drug Causes Weight Gain  -  Feb 14, 2007
WFIE-TV,Clozapine (Clozaril), a common treatment for schizophrenia and bipolar disorder, can cause massive weight gain in patients.

FDA handling of Lilly drug needs probe: scientist  -  Feb 13, 2007
ABC NewsAntipsychotics include Bristol-Myers Squibb's Abilify, Novartis AG's Clozaril, Lilly's Symbyax, AstraZeneca Plc's Seroquel, Johnson & Johnson's Risperdal

Link Found Between Antipsychotic Drugs and Weight Gain  -  Feb 13, 2007
Newsinferno.com,Scientists now claim that powerful drugs such as Zyprexa (olanzapine), Clozaril (clozapine), and Risperdal (risperidone) may affect production of an enzyme

Research Reveals How Antipsychotic Drugs Cause Weight Gain  -  Feb 12, 2007
Atlanta Journal Constitution (subscription),To test this theory, the researchers injected mice with clozapine (Clozaril), a drug commonly prescribed to treat schizophrenia and bipolar disorders in

Researchers discover why antipsychotic drugs cause weight gain  -  Feb 13, 2007
News-Medical.net,The discovery was made in tests carried out in mice who were injected mice with clozapine (Clozaril), a drug commonly prescribed to treat schizophrenia and

Agitation in the Elderly  -  Feb 16, 2007
Psychiatric Times,The newer atypical antipsychotic agents, such as risperidone (Risperdal), clozapine (Clozaril), olanzapine (Zyprexa) and quetiapine (Seroquel) offer the

Researchers discover why antipsychotics cause weight gain  -  Feb 15, 2007
Pharma Times (subscription),Therefore, suspecting that antipsychotic drugs might spike AMPK in the brain to overact, the Johns Hopkins team injected mice with Novartis' Clozaril

Hopkins scientists uncover cause of antipsychotic drug weight gain  -  Feb 12, 2007
EurekAlert (press release),Suspecting that antipsychotic drugs might spike AMPK in the brain to overact, the Johns Hopkins team injected mice with clozapine (Clozaril), which,

Could he have been saved?  -  Dec 16, 2006
Milwaukee Journal Sentinel (subscription),In the days leading up to his death, Murray's psychiatrist took him off Clozaril, an anti-psychotic medication that was starting to cause him liver problems

Report: Zyprexa maker minimized possible risks  -  Dec 17, 2006
USA TodayThe drugs, which also are the most widely used medications for aggressive, disruptive children, also include Risperdal, Seroquel, Clozaril, Geodon and

Latest Round of CATIE Data Sparks Many Questions  -  Dec 1, 2006
Psychiatric News,The team analyzed data comparing six antipsychotic medications—the FGA perphenazine versus the SGAs clozapine (Clozaril), olanzapine (Zyprexa),

California investigates anti-psychotics  Nov 3, 2006
Seroquel, and J&J's Risperdal. Clozapine is sold under the brand Clozaril by Novartis AG of Switzerland. In another government-funded ... -Life Style Extra, Addressing Psychiatric Comorbidities in Patients With Epilepsy  Oct 26, 2006
Chlorpromazine (Thorazine) at dosages exceeding 1000 mg/d and clozapine (Clozaril) at dosages exceeding 600 mg/d are the worst offenders, said Kanner. ... -Psychiatric Times, 21 physicians disciplined by Texas Medical Board  Oct 10, 2006
...risk management. The action was based on allegations that Fabre inadequately supervised a clinical trial for the drug Clozaril. A ... -Houston Chronicle, Florida has no list of foster kids on psychiatric drugs  24 Sep 2006
Among the drugs: Ritalin and Adderall for attention deficit hyperactivity disorder; antipsychotic drugs such as Risperdal, Clozaril and Geodon; Lithium for ... -Bradenton Herald

Louisiana Man Files Lawsuit Against Eli Lilly Alleging Zyprexa ...  Sep 19, 2006
Other popular atypical ant-psychotics include Risperdal, Seroquel, Clozaril and Geodon. Risperdal, Seroquel and Clozaril have all ... -Newsinferno.com

Eli Lilly and Suven enter CNS research deal  Aug 31, 2006
...including Coreg for congestive heart failure, Cozaar for high blood pressure, Zoladex for breast cancer, Buspar for anxiety and Clozaril for schizophrenia, as ... -OutSourcing-Pharma.com

Analysing Brain Changes In Schizophrenia & Bipolar Disorder  Aug 31, 2006
...month administration of two antipsychotic drugs used commonly in the treatment of schizophrenia and bipolar disorder - clozapine (Clozaril®) and haloperidol ... -Medical News Today

Latest Round of CATIE Data Sparks Many Questions  -  Dec 1, 2006
Psychiatric News,The team analyzed data comparing six antipsychotic medications—the FGA perphenazine versus the SGAs clozapine (Clozaril), olanzapine (Zyprexa),

USPSYCH: Diagnosing And Treating Bipolar Disorder  -  Nov 21, 2006
Psychiatric Times,Among the second-generation antipsychotics, Risperdal (risperidone) was associated with the least amount of weight gain (about 2 kg) while Clozaril

Generic clozapine: outcomes after switching formulations  Jul 31, 2006
The bioequivalence of these products compared with Clozaril® has not been unequivocally demonstrated. ... Generic clozapine is not inferior to Clozaril®. ... -British Journal of Psychiatry (subscription)

Generic clozapine: outcomes after switching formulations  Jul 31, 2006
The bioequivalence of these products compared with Clozaril® has not been unequivocally demonstrated. ... Generic clozapine is not inferior to Clozaril®. -British Journal of Psychiatry (subscription)

TeenScreen - Normal Kids Labeled Mentally Ill  Aug 23, 2006
SSRIs), like Paxil, Prozac, Zoloft, and Effexor, and atypical antipsychotics, such as Zyprexa, Risperdal, Geodon, Seroquel, Clozaril, and Abilify, and ADHD ... -Newstarget.com

Multiple Medication Use in General Practice and Psychiatry: So ...  Aug 23, 2006
Smoking can induce the metabolism of drugs such as clozapine (Clozaril), which are normally cleared by smoking-induced CYP1A2 (Hasegawa et al., 1993). ... -Psychiatric Times

Bush’s Mental Illness Screening Squad On the Move  Aug 11, 2006
SSRIs), like Paxil, Prozac, Zoloft, and Effexor, and the atypical antipsychotics, that include Zyprexa, Risperdal, Geodon, Seroquel, Clozaril, and Abilify. ... -Best Syndication

TeenScreen - Prescription Drug Pusher In Schools  22 Jul 2006
SSRIs), like Paxil, Prozac, Zoloft, and Effexor, and atypical antipsychotics, such as Zyprexa, Risperdal, Geodon, Seroquel, Clozaril, and Abilify. ... -OpEdNews

Novartis' Clozaril has serious health consequences, researchers ...  Jul 3, 2006
More than half the studied patients taking clozapine (marketed as Clozaril by Novartis) had metabolic syndrome, while only about 20% of those in a comparison ... -Pharmaceutical Business Review

Metabolic Syndrome Risk Doubles With Schizophrenia Drug  Jul 11, 2006
ROCHESTER, NY, July 11 -- Patients taking the antipsychotic Clozaril (clozapine) for schizophrenia need to be monitored for signs of metabolic syndrome ... -MedPage Today

Metabolic Syndrome Risk Doubles With Schizophrenia Drug  Jul 11, 2006
Monitor patients who are taking Clozaril (clozapine) for body mass index, lipid levels, fasting blood glucose levels, and blood pressure. ... -Psychiatric Times

Lawsuits: Only Weapon Against Big Pharma ToxicMeds  Jul 12, 2006
SSRIs), like Paxil, Prozac, Zoloft, and Effexor, and the atypical antipsychotics, that include Zyprexa, Risperdal, Geodon, Seroquel, Clozaril, and Abilify. ... -Conspiracy Planet

Medication Use and Older Adults  Jul 17, 2006
...antipsychotic drugs: Abilify (aripiprazole), Risperdal (risperidone), Zyprexa (olanzapine), Geodon (ziprasidone), Seroquel (quetiapine), and Clozaril (clozapine ... -FDA.gov

Drug Companies Still Peddling Risperdal and Zyprexa For Off-Label ...  Jun 21, 2006
None of the 6 drugs including Clozaril, Risperdal, Zyprexa, Seroquel, Abilify and Geodon are approved for the treatment of any other disorder in children or ... -SierraTimes.com

Antipsychotic Drug May Be Linked to Pituitary Tumors  Jul 13, 2006
Company/Otsuka America Pharmaceuticals, manufacturers of aripiprazole (Abilify); Novartis Pharmaceuticals, manufacturer of clozapine (Clozaril); Eli Lilly and ... -Newstarget.com

Cannabis is a First-Line Treatment for Childhood Mental Disorders  Jul 8, 2006
Prozac, Paxil, Maxalt, Immitrex, Depacote, Phenergan, Inderal, Thorazine, Amitriptaline, Buspar, Vicodin, Seroquel, Risperdal, Zyprexa, Clozaril, Norco, and ... -CounterPunch

Treatment-Resistant Schizophrenia: Making the Determination  Jul 11, 2006
...as an inadequate response from one adequate trial of a typical antipsychotic medication and two of the atypical antipsychotics, excluding clozapine (Clozaril). ... -Psychiatric Times



A generalised fit more beneficial to drug design  16 May 2006
...including Coreg for congestive heart failure, Cozaar for high blood pressure, Zoladex for breast cancer, Buspar for anxiety and Clozaril for schizophrenia, as ... - In-PharmaTechnologist.com

A rush to overprescribe?  May 1, 2006
Although the six drugs — Clozaril, Risperdal, Zyprexa, Seroquel, Abilify and Geodon — can be helpful in treating children with mental illness, critics say ... - USA Today

New anti-psychotic drugs carry risks for children  May 1, 2006
None of the six drugs — Clozaril, Risperdal, Zyprexa, Seroquel, Abilify and Geodon — is approved for kids, but doctors can prescribe them as "off-label ... - USA Today

Adult anti-psychotics can worsen troubles  May 1, 2006
These six new anti-psychotic drugs — Clozaril, Risperdal, Zyprexa, Seroquel, Abilify and Geodon — are not approved for children, but doctors can prescribe ... - USA Today

Behavioral and Pharmacologic Treatment of Aggression in Children ...  May 10, 2006
Clozapine (Clozaril), quetiapine (Seroquel), olanzapine (Zyprexa) and ziprasidone (Geodon) have been evaluated in small or uncontrolled studies and case ... - Psychiatric Times

Novartis Q1 net beats expectations on underlying growth ...  Apr 23, 2006
...pct in local currencies with strong performances from Diovan, Glivec, Femara, Comtan/Stalevo and Exelon offsetting weaker sales of Lamisil, Clozaril and Foradil ... - Forbes

(PZ) Novartis Delivers Strong Start to 2006 in First Quarter with ...  Apr 24, 2006
...currencies as strong performances from Diovan/Co-Diovan, Gleevec/Glivec, Femara, Comtan/Stalevo and Exelon offset lower sales of Lamisil, Clozaril and Foradil ... - Houston Chronicle

Recent Developments in Antipsychotic Use in Adults  Apr 20, 2006
Also reviewed is information about a new intramuscular (IM) formulation of olanzapine (Zyprexa) and an indication for clozapine (Clozaril) recently approved by ... - Psychiatric Times

Dealing with schizophrenia  Apr 18, 2006
...quite there.’’. Collins now takes eight medications daily and says they — particularly Clozaril — work far better. In 1996 ... - Lake Sun Leader (subscription)

Treatment Challenges in Schizophrenia: A Multifaceted Approach to ...  Apr 17, 2006
12 In 2002, clozapine (Clozaril) was approved by the FDA for reducing the risk of suicide in schizophrenic and schizoaffective patients. ... - Psychiatric Times





Clozaril drug shows promise  Apr 1, 2006
When patients in that situation were randomly assigned a second drug in the new study, Clozaril emerged as more effective than Risperdal, Seroquel and Zyprexa ... - Monterey County Herald

As methods of treatment change, patient population drops  Apr 10, 2006
...the process.". A new and improved generation of drugs, ones like clozaril, risperdal and zypreza, followed in the early 1990s. They ... - Palladium-Item

Study Could Alter Drug Treatments  Mar 31, 2006
...in white blood cells. Clozapine, sold by Novartis AG as Clozaril, is also made in generic form. Schizophrenia, a mental illness ... - Wall Street Journal (subscription)

Defying her mental illness, a Wichita woman rebuilds her life  Apr 1, 2006
...not quite there.". Collins now takes eight medications daily and says they -- particularly Clozaril--work far better. In 1996--with ... - Kansas.com

Managing Compliance  Apr 2, 2006
...antipsychotics is unknown, but estimates for specific agents vary from 25% for haloperidol (Haldol) to almost none with clozapine (Clozaril) (Segraves, 1999a). ... - Psychiatric Times

Comorbid Tobacco Dependence and Psychiatric Disorders  Mar 26, 2006
Patients treated with atypical antipsychotic agents, especially clozapine (Clozaril), smoke less (George et al., 1995; McEvoy et al., 1999, 1995) and have an ... - Psychiatric Times

FDA-Approved Office Lithium Test Expected To Enhance Clinical Care  Mar 24, 2006
...an office-based system for detecting suppressed white blood cell and absolute neutrophil cell levels for use in patients being treated with clozapine (Clozaril ... - Psychiatric Times

Clozaril-Risperdal Duo Lacks Efficacy Against Schizophrenia  Feb 1, 2006
1 - When severe schizophrenia is refractory to Clozaril (clozapine), adding Risperdal (risperidone) to the mix appears to make little difference, a study here ... - MedPage Today,

Monoaminergic Treatment of Schizophrenia  Feb 27, 2006
Since recent data demonstrate that atypical antipsychotics, such as clozapine (Clozaril), have D 1 antagonist activity (Cussac et al., 2004), several ongoing ... - Psychiatric Times,

Multiple drugs may not help schizophrenics: Study  Feb 3, 2006
The study, published in the New England Journal of Medicine, tested 68 patients who responded poorly to clozapine, the generic version of Novartis AG's Clozaril ... - Zee News,

Advocates for mentally ill fear Medicare plan is problematic  Feb 22, 2006
He had been on Medicaid but now belongs to a United Healthcare plan. Mr. Shannon takes Clozaril to treat his schizophrenia. Because ... - WFAA (subscription),

State agency consider Lyon's release  Feb 12, 2006
Joan Lyon got a call about a year ago from her son's caseworker who said Christopher was responding well to the powerful anti-psychotic drug, Clozaril. ... - Myrtle Beach Sun News,

Exploring Treatment Options for Patients with Autism  Feb 6, 2006
While antipsychotic medications such as clozapine (Clozaril®), risperidone (Risperdal®), olanzapine (Zyprexa®), and quetiapine (Seroquel®) may decrease ... - DailyIndia.com,

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