Recent news on Crixivan

International panel issues new HIV/HCV co-infection guidelines  -  May 24, 2007
Aidsmap,Although atazanavir (Reyataz) and indinavir (Crixivan) can cause elevated bilirubin levels, this does not reflect liver damage.

Merck & Co Statement on Brazilian Government's Decision to Issue ...  -  May 5, 2007
ag-IP-news Agency,In fact, Merck's global HIV pricing policy offers Brazil access to both STOCRIN and CRIXIVAN at the lowest price of any country with a comparable wealth and

No major metabolic differences between PI-based and NNRTI-based ...  -  Apr 29, 2007
Aidsmap,...during that period: nelfinavir (Viracept) was the most commonly used PI (61%), followed by ritonavir-boosted PIs (24%) and indinavir (Crixivan) (12%).

Some HIV Drugs May Up Heart Risk  -  Apr 25, 2007
WebMDExamples of some protease inhibitors are Crixivan, Norvir, Viracept, Agenerase, and Kaletra. Other HIV drugs called nonnucleoside reverse-transcriptase

Some HIV Drugs May Up Heart Risk  -  26 Apr 2007
WebMDExamples of some protease inhibitors are Crixivan, Norvir, Viracept, Agenerase, and Kaletra. Other HIV drugs called nonnucleoside reverse-transcriptase

European Inventor of the Year Awards honour pioneering research  -  Apr 19, 2007
Cordis News,It was their invention of Crixivan, a protease inhibitor that has revolutionised HIV treatment, which attracted the attention of the panel of judges.

The Limits of a Promising Drug  -  Apr 22, 2007
Barron's (subscription)Kolbert is that better HCV drugs will arrive and supplant the Vertex product -- as happened to the pioneering antivirals for HIV like Merck's Crixivan.

Inventors of the year awards 2007: Biodegradable plastics, airbags ...  -  Apr 20, 2007
EurofundingMag,Non-European countries: Dr Joseph P. Vacca and team (Merck Research Laboratories, West Point, PA/USA) for inventing Crixivan, a protease inhibitor which has

Top Euro award for British inventor  -  Apr 18, 2007
Channel 4 News,...plastics obtained from starch, and US scientist Dr Joseph Vacca for inventing Crixivan, a protease inhibitor which has revolutionised HIV treatment.

Broadway Actress/HIV Advocate, Sheryl Lee Ralph, Unveils Winning ...  -  Apr 16, 2007
Drug Newswire (press release),Propulsid(R) (cisapride), Camptosar(R) (irinotecan hydrochloride), Crixivan(R) (indinavir sulfate), Mevacor(R) (lovastatin), Zocor(R) (simvastatin),

Merck Reports Strong Financial Results for First-Quarter 2007  -  Apr 19, 2007
Business Wire (press release),Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ, JANUVIA, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN,

Not so happy feet  -  Mar 21, 2007
NAPWA,...taken d4T in the past, increasing age (as getting older causes nerve damage anyway) and possibly the use of the protease inhibitor indinavir (Crixivan).

House Committee Considers Holding Hearings To Investigate Pricing ...  -  Mar 15, 2007
Kaiser network.org,Norvir is used primarily as a booster for other protease inhibitors, such as Bristol-Myers Squibb's Reyataz and Merck's Crixivan.

MSD provides relief for Kenya's PLWA  -  Feb 16, 2007
Africa Science News Service,Merck first announced that it was reducing the prices of STOCRIN and CRIXIVAN in developing countries to prices at which the Company makes no profit on

Merck, Pfizer HIV Drugs May Spark a Second Revolution (Update1)  -  Feb 15, 2007
BloombergMerck, the Whitehouse Station, New Jersey-based maker of Crixivan for HIV, used a different strategy with MK-0518, preventing the virus from integrating its

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,Next came HIV protease inhibitors such as Roche's Invirase/Fortovase (saquinavir), Abbott Laboratories Norvir (ritonavir), Merck & Co's Crixivan (indinavir)

Zacks Analyst Blog Highlights: Vertex Pharmaceuticals ...  -  Feb 6, 2007
Business Wire (press release),...has a convenient dosing and favorable metabolic profile relative to first-generation protease inhibitors such as Agenerase, Crixivan, and Viracept.

Be careful if using fosamprenavir/ritonavir for PEP, and did HCV ...  -  Jan 31, 2007
Aidsmap,In December 2003, a 24 year-old gay man was prescribed PEP consisting of Combivir and indinavir (Crixivan) for four weeks following receptive unprotected

Merck Announces 2006 Financial Results that Demonstrate Solid ...  -  Jan 30, 2007
Business Wire (press release),COSOPT, CRIXIVAN, EMEND, INVANZ, JANUVIA, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC/TIMOPTIC XE, TRUSOPT, VASOTEC/VASERETIC and ZOLINZA.

Wall Street Journal Examines Reason Abbott Increased Price of ...  -  Jan 3, 2007
Kaiser network.org,Norvir is used primarily as a booster for other protease inhibitors, such as Bristol-Myers Squibb's Reyataz and Merck's Crixivan ( Kaiser Daily HIV/AIDS

The ones HIV left in limbo  -  Jan 2, 2007
Los Angeles Times,Fuzeon (two injections a day to help prevent the virus from fusing with normal cells); Crixivan (two pills a day; a protease inhibitor that interferes

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

Merck Remains Confident in Future Growth as it Executes on New ...  -  Dec 12, 2006
Genetic Engineering News (press release),Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN,

Merck Gets Punk'd by Thailand  -  Dec 16, 2006
Motley FoolIn 2004, global combined sales of Crixivan (indinavir)/Stocrin (Efavirenz) reached $256 million. Thailand's Health Ministry has argued that it cannot afford

my private weblog  Oct 31, 2006
These include quinidine, procainamide, amiodarone 2006 inurl levitra march p sotalol.ritonavir (Norvir®) or indinavir sulfate (Crixivan®)ketoconazole or ... -Digital Divide Network, New risk factors for severe liver toxicity identified in largest ...  Nov 3, 2006
...reverse transcriptase inhibitor (NNRTI), either nevirapine or delavirdine; or two NRTIs and a single, unboosted, protease inhibitor, indinavir (Crixivan). ... -Aidsmap, Merck & Co: broadening the anti-infective portfolio  Nov 2, 2006
The company has a broad anti-infective portfolio covering HIV drugs (protease inhibitor Crixivan), antibiotics (Invanz and Primaxin) and antifungals (Cancidas ... -Pharmaceutical Business Review Bristol could get PR boost from AIDS drug  Oct 9, 2006
Truvada sales totaled $548 million, Sustiva totaled $368 million and sales of Stocrin - used in combination with Merck's AIDS drug Crixivan - totaled $156 ... -CNNMoney.com FDA Approves REYATAZ(R) (atazanavir sulfate) 300 mg Single Capsule ...  Oct 24, 2006
REYATAZ should not be taken with the following medicines: ergot medicines, Versed(R), Halcion(R), Orap(R), Propulsid(R), Camptosar(R), Crixivan(R), Mevacor(R ... -Drug Newswire (press release), Aptivus®(tipranavir) Demonstrates Durable Response Through Nearly ...  Oct 15, 2006
...comparator protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r (Crixivan®). ... -Medical News Today (press release), Business news in brief  Oct 13, 2006
...treatments. Merck already makes Crixivan and Stocrin, and it says it is testing two other products, including an HIV vaccine. The ... -Philadelphia Inquirer, FDA Approves REYATAZ® (atazanavir Sulfate) 300 Mg Single Capsule ...  Oct 23, 2006
REYATAZ should not be taken with the following medicines: ergot medicines, Versed®, Halcion®, Orap®, Propulsid®, Camptosar®, Crixivan®, Mevacor®, Zocor ... -Medical News Today (press release), Merck Announces Strong Financial Results for the Third Quarter ...  Oct 20, 2006
Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC ... -Business Wire (press release), Merck Remains Confident in Future Growth as it Executes on New ...  -  12 Dec 2006
Genetic Engineering News (press release),Sales forecasts for those products for 2006 are as follows: * Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ ...

Long-Term Data Show Aptivus(R) (tipranavir) Continues to ...  -  Nov 15, 2006
Juraforum.de,...comparator protease inhibitors that include lopinavir/r (Kaletra(R)), amprenavir/r (Agenerase(R)), saquinavir/r (Invirase(R)) and indinavir/r (Crixivan(R)).(1 ...

HIV :: 24-week results from Aptivus, tipranavir  -  Nov 20, 2006
SpiritIndia,...boosted comparator protease inhibitors that include lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®), and indinavir/r (Crixivan ...

Large analysis shows benefits of starting treatment with efavirenz  Aug 22, 2006
...boosted protease inhibitors included were amprenavir (Agenerase), lopinavir (Kaletra), saquinavir (Invirase / Fortovase) and indinavir (Crixivan): newer drugs ... -Aidsmap

NRTI-sparing combination of ritonavir-boosted indinavir and ...  Aug 9, 2006
...show modest improvements in fat loss from under the skin after switching to a combination of ritonavir (Norvir)-boosted indinavir (Crixivan) and efavirenz ... -Aidsmap

Cause of ALS yet unknown; cure is far off  Aug 20, 2006
...in treating ALS, including the antibiotic minocycline (Minocin), the breast-cancer drug tamoxifen (Nolvadex), the HIV/AIDS drug indinavir (Crixivan), the COX-2 ... -Fort Wayne Journal Gazette

AIDS drug works as first treatment in study  Aug 12, 2006
The two others are reverse transcriptase, which is targeted by drugs including Viread, and protease, attacked by Merck's Crixivan and other medicines. ... -Deseret News

The Lancet Publishes 48-week Results From Tipranavir RESIST ...  Aug 8, 2006
...protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r (Crixivan®), through 48 ... -DG News

Lowered AZT dose for low weight patients 'effective and reduces ...  Aug 9, 2006
...line potent antiretroviral therapy regimen that consisted of zidovudine 200mg, lamivudine (3TC) 150mg, and ritonavir-boosted indinavir (Crixivan) 600mg/100mg ... -Aidsmap

Nevirapine-based triple-drug combinations safe for use in pregnant ...  Jul 10, 2006
Only ten of the 46 women with severe toxicity needed to change treatment, replacing nevirapine with either nelfinavir (Viracept) or indinavir (Crixivan). ... -Aidsmap

Blunder at Merck's biggest production site pollutes creek  Jul 7, 2006
It also produces drugs such as Crixivan for AIDS, Fosamax for osteoporosis and Zocor for high cholesterol, and even contract manufactures for the likes of ... -BiopharmaReporter.com

Clinical Pharmacology of Antiretroviral Therapy -- New Data for ...  Jun 22, 2006
Indeed, indinavir (Crixivan, Merck), and to a lesser extent lopinavir, clearance was influenced by orosomucoid concentration and phenotype. ... -Medscape (subscription)



Merck Announces Strong Financial Results for the First Quarter ...  Apr 20, 2006
...to $2.6 billion Other reported products* $6.3 to $6.6 billion * Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ ... - Business Wire





Study finds no link between brain-penetrating antiretroviral drugs ...  Mar 21, 2006
...zidovudine, Retrovir), d4T (stavudine, Zerit), 3TC (lamivudine, Epivir), abacavir (Ziagen), nevirapine (Viramune), efavirenz (Sustiva) and indinavir (Crixivan ... - Aidsmap

Merck Sharp and Dohme (MSD) Again Reduces Price of STOCRIN ...  Mar 16, 2006
...countries were being treated with antiretroviral regimens containing either of MSD's two current HIV/AIDS medicines, STOCRIN and CRIXIVAN (indinavir sulfate). ... - AllAfrica.com

USM Alumna speaks on drug development  Mar 13, 2006
...development, and another part in which she illustrated the development process with a drug she helped develop, the protease inhibitor Crixivan, a pioneering ... - The Student Printz

Merck cuts Aids drug price  Mar 9, 2006
...manufacturing process made the lower prices possible. A second Merck drug, Crixivan, is also sold at a lower price in the developing world. - News24

Drug maker Merck & Co. has announced that it is lowering the price ...  Mar 7, 2006
...process made the lower prices possible. A second Merck drug, Crixivan, is also sold at a lower price in the developing world. (AP). - NDTV.com

Researchers Disprove Fat Redistribution Syndrome Among Men Taking ...  Mar 21, 2006
...and limbs. The syndrome is known among AIDS patients and care providers as "Crix belly," after the HIV drug Crixivan. "Changes in ... - eMaxHealth.com

US firm cuts price of Aids drug  Mar 13, 2006
...year, nearly 500,000 patients in 76 developing countries were on antiretroviral regimens containing either of MSD’s two current HIV drugs Stocrin and Crixivan ... - Standard

Aids: Stocrin price cut to lead to more reductions  Mar 21, 2006
At the end of 2005, nearly 500,000 patients in 76 developing countries were being treated with regimens containing either Stocrin or Crixivan, two of MSD’s ... - East African

Chemist Wins National Award for Contributions in Medicinal ...  Mar 21, 2006
This research resulted in the development of the HIV protease inhibitor Crixivan® and the HIV reverse transcriptase inhibitor Sustiva®. ... - Newswise

US firm reduces price of ARVs  Mar 7, 2006
...were being treated with antiretroviral regimens containing either of MSDís two current HIV and AIDS medicines, STOCRIN and CRIXIVAN (indinavir sulfate). ... - The Swazi Observer

Bristol-Myers Squibb Seeks To Expand Access To Its Most Recently ...  Feb 19, 2006
Reyataz should not be taken with the following medicines: ergot medicines, Versed®, Halcion®, Orap®, Propulsid®, Camptosar®, Crixivan®, Mevacor®, Zocor ... - Medical News Today,

New 48 Week Clinical Trial Data Reported Comparing REYATAZ(R) ...  Feb 9, 2006
REYATAZ should not be taken with the following medicines: ergot medicines, Versed(R), Halcion(R), Orap(R), Propulsid(R), Camptosar(R), Crixivan(R), Mevacor(R ... - Finanzen.net,

New 48 Week Clinical Trial Data Reported Comparing REYATAZ(R) ...  09 Feb 2006
REYATAZ should not be taken with the following medicines: ergot medicines, Versed®, Halcion®, Orap®, Propulsid®, Camptosar®, Crixivan®, Mevacor®, Zocor ... - Yahoo! News

AIDS drugs don't work for all  Feb 4, 2006
...a week to boost his white blood cell count); Fuzeon (two injections a day to help prevent the virus from fusing with normal cells); Crixivan (two pills a day ... - Pittsburgh Post Gazette

Merck Announces Strong Full-Year and Fourth-Quarter 2005 Earnings ...  Jan 31, 2006
Other reported products comprise: AGGRASTAT, ARCOXIA, CANCIDAS, COSOPT, CRIXIVAN, EMEND, INVANZ, MAXALT, PRIMAXIN, PROPECIA, PROSCAR, STOCRIN, TIMOPTIC ... - TMCnet

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