Recent news on Cyclophosphamide

Exclusive Sisters stun docs by battling back from illness hell  -  25 May 2007
Glasgow Daily Record,Three months ago, Kayla was given the chemotherapy drug Cyclophosphamide - normally used to treat a number of cancers - to prevent further damage to her

La Jolla Pharmaceutical Company Reports Riquent(R) Well Tolerated ...  -  25 May 2007
Medical News Today (press release),...primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide.

Adding rituximab improves response in cyclophosphamide-resistant lupus  -  May 1, 2007
Therapeutics Daily (subscription) (press release),NEW YORK (Reuters Health) - Patients with cyclophosphamide-resistant proliferative lupus nephritis show a clinical and histological response when rituximab

Course Directors: Robert S. Mocharnuk, MD  -  May 3, 2007
Clinical Care Options (subscription),Phase III randomized trial of doxorubicin and docetaxel versus doxorubicin and cyclophosphamide as primary medical therapy in women with breast cancer: an

Making Science Personal: Lilly Oncology to Unveil 76 Studies at ...  -  May 23, 2007
campus med,2:00 pm -- Neoadjuvant chemotherapy with a dose-dense sequential combination of epirubicin and cyclophosphamide followed by paclitaxel and gemcitabine

US FDA Approves VELCADE(R) + DOXIL(R) Combination for Treatment of ...  -  May 21, 2007
PR Newswire (press release),...occur at lower cumulative doses (400 mg/m2) in patients with prior mediastinal irradiation or who are receiving concurrent cyclophosphamide therapy.

Methods for treating lupus nephritis  -  May 20, 2007
News-Medical.net,Grootscholten treated two groups of patients for two years with either drips containing cyclophosphamide (treatment 1) or a combination of drips containing

Neoadjuvant Taxotere®, Navelbine®, and Herceptin® Active for ...  -  May 3, 2007
Cancer Consultants (press release),All patients received neoadjuvant therapy, followed by surgery and additional chemotherapy with doxorubicin and cyclophosphamide.

Rituxan Phase II Data in Patients with Relapsing-Remitting ...  -  May 2, 2007
PipelineReview.com (press release),Rituxan received FDA approval in February 2006 for the treatment of diffuse large B-cell lymphoma (DLBCL) in combination with CHOP (cyclophosphamide,

Lupus nephritis treatment has pros, cons  -  May 15, 2007
Earthtimes.org...with lupus nephritis -- inflammation of the kidney caused by lupus -- for two years with either drips containing cyclophosphamide, treatment No.

Deadly Cancers Dealt A Knockout Punch  -  May 14, 2007
Medical News Today (press release),Another presentation at the Arizona conference reported on the use of Reolysin plus the cancer drug cyclophosphamide in an animal model of melanoma.

And courage  -  May 13, 2007
Wilkes Barre Times-Leader,Lydia will get two different chemotherapy treatments, cyclophosphamide and doxorubicin during her stay in Baltimore, along with the vaccine itself – four

YM BioSciences reports third quarter 2007 operational and ...  -  May 11, 2007
CNW Telbec (Communiqués de presse),...with epirubicin and cyclophosphamide for the treatment of rapidly progressing metastatic breast cancer completed the third planned interim analysis.

Full Text  -  May 3, 2007
Science Magazine (subscription)For example, when the researchers treated mice that had Lewis lung carcinoma with thymosin 1 , interferon, and cyclophosphamide, they found that "this

Biogen Idec Reports First Quarter 2007 Results  -  May 2, 2007
PharmaLive.com (press release),The LUCID trial will compare treatment with lumiliximab in combination with fludarabine, cyclophosphamide, and RITUXAN (FCR), an emerging standard of care,

Fullerenes To Cure Leukemia  -  Apr 27, 2007
Russia-InfoCenter,Researchers showed that combination of nitroxide methanofullerenes with cyclophosphamide cures leukemia R-338; however, individual introduction of same

Exercise May Reduce Fatigue, Nausea Associated With Adjuvant ...  -  Apr 26, 2007
Medscape (subscription)Most of the women (79%) received standard AC chemotherapy, consisting of doxorubicin and cyclophosphamide on a 21-day cycle.

La Jolla Pharmaceutical Receives Riquent(R) Composition of Matter ...  -  26 Apr 2007
PR Newswire (press release),...primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide.

Spectrum Pharmaceuticals Announces Data From Three Oncology ...  -  Apr 19, 2007
PR Newswire (press release),The present study was conducted to evaluate the effect of SPI (IRL)-1620 on the efficacy of cyclophosphamide and cisplatin in ovarian tumor bearing athymic

Market Report -- In Play (ZIOP)  -  Apr 16, 2007
MSN MoneyData presented demonstrated oral availability of ZIO-201 and activity in a variety of cancer models, including those with ifosfamide and cyclophosphamide

Current Treatment of Malignant Pheochromocytoma  -  Apr 4, 2007
Journal of Clinical Endocrinology and Metabolism,Similar to cytotoxic chemotherapy with cyclophosphamide, vincristine, and dacarbazine, MIBG can induce remission for a limited period in a significant

Taxane Use And Dose-Dense Scheduling May Benefit Patients With ...  -  Apr 14, 2007
Medical News Today (press release),Paclitaxel after doxorubicin plus cyclophosphamide as adjuvant chemotherapy for node-positive breast cancer: results from NSABP B-28.

Smokers, cancer survivors at heart risk  -  Apr 23, 2007
The Brunei Times,..."Patients who underwent radiotherapy plus adjuvant chemotherapy (cyclophosphamide, methotrexate, and fluorouracil) after 1979 had a higher risk of

Stem Cells Tame Type 1 Diabetes in Pilot Study  -  Apr 10, 2007
MedPage Today,The patients were first treated with cyclophosphamide (Cytoxan) 2.0 g/m 2 ) and G-CSF (10 μg/kg per day) to mobilized the stem cells, which were then

Autologous Nonmyeloablative Hematopoietic Stem Cell ...  -  Apr 10, 2007
Journal of American Medical Association (subscription),Hematopoietic stem cells were mobilized with cyclophosphamide (2.0 g/m 2 ) and granulocyte colony-stimulating factor (10 µg/kg per day) and then collected

Total Lymphoid Irradiation and Stem Cell Transplantion Very ...  -  Apr 5, 2007
Cancer Consultants (press release),The current study evaluated a regimen of TLI followed by high-dose etoposide, cyclophosphamide and carboplatin in 32 patients and high-dose chemotherapy

Mixing Adjuvant Therapies Prolongs Early Breast Cancer Survival  -  Apr 4, 2007
Psychiatric Times,In most cases, chemotherapy consisted of cyclophosphamide (Cytoxan), methotrexate, and 5-fluorouracil (87%) or anthracycline-based regimens (11%),

Neoadjuvant Taxotere®, Navelbine® and Herceptin® Active for ...  -  Apr 4, 2007
Cancer Consultants (press release),All patients underwent surgery followed by adjuvant doxorubicin and cyclophosphamide. These authors reported that 94% of patients had a clinical response

Spectrum Pharmaceuticals (SPPI) Announces Data From Three Oncology ...  -  Apr 19, 2007
StreetInsider.com (subscription),Also, the company announces SPI (IRL)-1620 enhances efficacy of radiation, cisplatin and cyclophosphamide in eexperimental models.

Stem Cell Transplants not Superior to Intensive Adjuvant Therapy ...  -  Apr 17, 2007
Cancer Consultants (press release),...with CTCb (cyclophosphamide, thiotepa, carboplatin) or 9 cycles of tailored FEC with granulocyte colony-stimulating factor (Neupogen®) support.

ZIOPHARM Presents Data on Orally Active ZIO-201 at AACR  -  Apr 16, 2007
PharmaLive.com (press release),...oral availability of ZIO-201 and activity in a variety of cancer models, including those with ifosfamide (IFOS) and cyclophosphamide resistant tumors.

Studies Evaluate Combined Adjuvant Therapy for Early Breast Cancer  -  Apr 16, 2007
Cancer Consultants (press release),The first trial evaluated the effect of adding combination chemotherapy (most commonly consisting of cyclophosphamide, methotrexate, and 5-fluourouracil) to

GSK Initiates Repeat Dosing Study Of Its Novel Oral Platelet ...  -  Apr 16, 2007
Medical News Today (press release),...in patients previously treated for chronic ITP, examples of which includesplenectomy, corticosteroids, immunoglobulins, cyclophosphamide and rituximab.

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic ...  -  Apr 15, 2007
News-Medical.net,...in patients previously treated for chronic ITP, examples of which include splenectomy, corticosteroids, immunoglobulins, cyclophosphamide or rituximab.

Spectrum Pharmaceuticals Announces Three Presentations at 2007 ...  -  Apr 12, 2007
PR-Inside.com (Pressemitteilung),Number: 4058 Presentation Title: ETB Receptor Agonist, IRL-1620, Enhances The Efficacy Of Cyclophosphamide And Cisplatin In Ovarian Tumor Bearing Mice.

Genta Appeals FDA Decision on Genasense(R) in CLL  -  Apr 5, 2007
Drug Newswire (press release),In the pivotal Phase 3 trial, patients with relapsed or refractory CLL were randomly assigned to receive fludarabine plus cyclophosphamide (Flu/Cy)

Genta Appeals FDA Decision On Genasense In CLL - Update  -  Apr 4, 2007
Trading Markets,...relapsed or refractory CLL, who were randomly assigned to receive fludarabine plus cyclophosphamide (Flu/Cy) chemotherapy with or without Genasense.

Genta Appeals FDA Decision on Genasense(R) in CLL  -  Apr 4, 2007
PR Newswire (press release),Genasense in CLL In the pivotal Phase 3 trial, patients with relapsed or refractory CLL were randomly assigned to receive fludarabine plus cyclophosphamide

La Jolla Pharmaceutical Provides Update on Interim Antibody ...  -  Mar 28, 2007
Drug Newswire (press release),...primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide.

John still treating Malawi sick!  -  Mar 28, 2007
Fermanagh Herald (subscription),Today, the drug cyclophosphamide does the trick and, in fact, some £1850 of Dr Phillips £2000 prizemoney for his 'Lancet' article was sent off to Lilongwe

Coping and hoping: Telling cancer's tales  -  Apr 5, 2007
Philadelphia Inquirer,...followed by a combination chemotherapy regimen called CMF, for the cancer-killing drugs cyclophosphamide, methotrexate and 5-fluorouracil.

Health Alert: Lung drug  -  Feb 21, 2007
WIS,Now researchers at UCLA say cyclophosphamide, a drug typically used to treat cancer, may help slow down lung damage. Dr. Clements says, "Our trial was

YM BioSciences announces termination of the tesmilifene Phase III ...  -  Feb 1, 2007
Drug Newswire (press release),The pivotal Phase III trial compared the survival of patients treated with tesmilifene combined with epirubicin/cyclophosphamide to

Biogen starts leukemia trial  -  Feb 7, 2007
Boston Globe,Biogen Idec said its trial will compare treatment with lumiliximab in combination with fludaribine, cyclophosphamide, and rituximab, an emerging standard of

YM BioSciences Halts Breast Cancer Trial  -  Jan 30, 2007
Forbes,...spreading and/or recurrent breast cancer treated with either tesmilifene combined with epirubicin/cyclophosphamide or epirubicin/cyclophosphamide alone.

YM BioSciences shares plummet 55% after breast cancer drug trial ...  -  Jan 31, 2007
CBC News,The trial compares the survival of patients treated with tesmilifene combined with epirubicin-cyclophosphamide to epirubicin-cyclophosphamide alone in women

Paraplatin®/Cytoxan® a Possible Alternative for Ovarian Cancer  -  Feb 20, 2007
Cancer Consultants (press release),Carboplatin/cyclophosphamide or carboplatin/paclitaxel in elderly patients with advanced ovarian cancer? Analysis of two consecutive trials from the group

Genasense® Combination Therapy Effective for CLL  -  Feb 20, 2007
Cancer Consultants (press release),Randomized phase III trial of fludarabine plus cyclophosphamide with or without oblimersen sodium (Bcl-2 antisense) in patients with relapsed or refractory

Improving Outcomes in Lymphoma  -  Feb 5, 2007
Medscape (subscription)Rituximab has been incorporated into different approaches and regimens for indolent lymphoma, including CVP (cyclophosphamide, vincristine, and prednisone),

First Antisense Drug Provides Benefit To Subset Of Chronic ...  -  Feb 20, 2007
Medical News Today (press release),It enrolled 241 patients at cancer centers worldwide who were randomized to receive fludarabine combined with cyclophosphamide chemotherapy or the same

Investigational Drug May Prevent or Reverse Chemotherapy ...  -  Feb 7, 2007
Cancer Consultants (press release),All women received chemotherapy consisting of cyclophosphamide, doxorubicin, and fluorouracil. Half the women also received dofequidar.

Genta Announces the Company Will Appeal FDA Action on New Drug ...  -  Feb 7, 2007
PipelineReview.com (press release),In the pivotal Phase 3 trial, patients with relapsed or refractory CLL were randomly assigned to receive fludarabine plus cyclophosphamide (Flu/Cy)

Poor-Prognosis Germ Cell Tumors: We Have Not Yet Crossed The ...  -  Feb 19, 2007
Medical News Today (press release),...cycles of BEP followed by 2 cycles of high dose chemotherapy with carboplatin, etoposide, and cyclophosphamide and autologous stem cell rescue on day 5.

Genta publishes encouraging results on cancer therapy  -  Feb 14, 2007
Pharmaceutical Business ReviewIn the trial patients with relapsed or refractory chronic lymphocytic leukemia (CLL) received fludarabine plus cyclophosphamide chemotherapy with or without

Camptosar® Evaluated in Children with Relapsed or Refractory ...  -  Feb 14, 2007
Cancer Consultants (press release),Active agents for the treatment of recurrent or refractory rhabdomyosarcoma include Cytoxan® (cyclophosphamide), Ifex® (ifosfamide),

Biogen Idec Reports Full Year and Fourth Quarter 2006 Results  -  Feb 15, 2007
WebWire (press release),...may be synergistic with fludarabine, cyclophosphamide and rituximab (FCR), an emerging standard of care for chronic lymphocytic leukemia (CLL) patients.

Genmab Announces Year End 2006 Financial Results  -  Feb 13, 2007
PR Newswire (press release),HuMax-CD20 in combination with fludarabine and cyclophosphamide for CLL Advanced pre-clinical pipeline - HuMax-CD38(TM) shown to be first antibody known

When they said I had cancer I thought 'I'm going to die'  -  Feb 13, 2007
Daily Mail,Chemotherapy started immediately using CHOP (the drugs Cyclophosphamide, Doxorubicin, Vincristine and Prednisolone) every fortnight for 12 weeks.

The obvious is easy to miss  -  Feb 12, 2007
Los Angeles Times,It is also crucial to obtain special blood tests, and a tissue sample to confirm vasculitis before considering a toxic chemotherapy like cyclophosphamide,

Combination of Irinotecan and Vincristine Active Against ...  -  Feb 12, 2007
Cancer Consultants (press release),...treatment with irinotecan and vincristine alternating with the commonly used VAC chemotherapy regimen (vincristine, dactinomycin, and cyclophosphamide).

Biogen Idec Initiates Randomized, Registrational Trial Of ...  -  Feb 12, 2007
Medical News Today (press release),The trial will compare treatment with lumiliximab in combination with fludaribine, cyclophosphamide and rituximab (FCR), an emerging standard of care,

YM Biosciences Reports Second Quarter 2007 Operational and ...  -  Feb 9, 2007
CNW Telbec (Communiqués de presse),...with epirubicin and cyclophosphamide for the treatment of rapidly progressing metastatic breast cancer completed the third planned interim analysis.

Lumiliximab Granted Orphan Drug Status and Fast Track Status  -  Feb 9, 2007
Cancer Consultants (press release),Biogen Idec has initiated a clinical trial comparing lumiliximab in combination with FCR (fludarabine, cyclophosphamide and rituximab) to FCR alone in

La Jolla Pharmaceutical Company to Present at BIO CEO & Investor ...  -  Feb 8, 2007
PR Newswire (press release),...primary endpoint, time to renal flare, or with respect to its secondary endpoint, time to treatment with high-dose corticosteroids or cyclophosphamide.

Immunomedics Announces Second Quarter Fiscal 2007 Results  -  Feb 8, 2007
PR Newswire (press release),...showing that adding epratuzumab to rituximab and combined cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy to treat patients with

Biogen gets fast track, orphan status for leukemia drug  -  Feb 8, 2007
Milwaukee Business Journal,The trial will compare treatment with lumiliximab in combination with fludaribine, cyclophosphamide and rituximab (FCR) to FCR alone in patients with CLL

Biotech Stocks Day-in-Review: IPOs Heat Up  -  Feb 8, 2007
Seeking Alpha,Lumiliximab will be administered together with fludaribine, cyclophosphamide and rituximab (FCR), and compared to FCR alone. At the same time,

Signs of lung cancer  -  Feb 6, 2007
Malaysia Star,In SCLC, dose-intensive combinations of cisplatin, vincristine, doxorubicin and etoposide are used, as are the standard doses of cyclophosphamide,

Market Report -- In Play (BIIB)  -  Feb 7, 2007
MSN MoneyThe trial will compare treatment with lumiliximab in combination with fludaribine, cyclophosphamide and rituximab, to FCR alone in patients with CLL that

Concurrent Chemotherapy and Radiation Therapy Reduces Locoregional ...  -  Feb 6, 2007
Cancer Consultants (press release),The chemotherapy regimen that was given to both groups of patients consisted of mitoxantrone, fluorouracil, and cyclophosphamide.

Solo Capecitabine Shows Good Results in Advanced Breast Cancer ...  -  Feb 6, 2007
DG NewsA phase 3 trial in this setting reported in December 2006 demonstrated a significant survival benefit with capecitabine versus conventional cyclophosphamide

Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial ...  -  Feb 6, 2007
PharmaLive.com (press release),...sensitive small cell lung cancer are a variety of single agent and combination regimens including topotecan, cyclophosphamide, doxorubicin, vincristine,

Genta Announces the Company Will Appeal FDA Action on New Drug ...  -  Feb 6, 2007
PR Newswire (press release),Genasense in CLL In the pivotal Phase 3 trial, patients with relapsed or refractory CLL were randomly assigned to receive fludarabine plus cyclophosphamide

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