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Alzheimer's Treatments and Medications  -  May 19, 2007
HealthCentral.com,The three most commonly prescribed cholinesterase inhibitors are donepezil (approved in 1996), rivastigmine (approved in 2000), and galantamine (approved in

Alzheimer's drug may restore speech in stroke sufferers  -  May 14, 2007
NewKerala.com,London, May 14 : Spanish researchers have found that Alzheimer's drug Donepezil may help people who have had a stroke speak again.

Alzheimer's Drug may Help to Restore Speech in Stroke Patients  -  May 14, 2007
MedIndia,Spanish researchers have found that Alzheimer’s drug Donepezil may help people who have had a stroke speak again. Marcelo Berthier of the M dico-Sanitarias

Smart drugs for straight As  -  May 13, 2007
Times Online,A drug prescribed for Alzheimer’s disease – donepezil – has been shown to delay loss of mental ability in patients and, more recently, to boost performance

New Claims For Banned Alzheimer's Drugs  -  May 15, 2007
Sky News,Their research showed that patients prescribed donepezil, rivastagmine and galantamine had 70% fewer of the proteins linked to brain plaques associated with

Alzheimer's drug's impact hailed  -  May 14, 2007
BBC News,Post-mortem examinations were done on 12 patients who took part in UK trials of the drugs - donepezil, rivastigmine, tacrine and galantamine.

Drugs 'have Alzheimer's benefits'  -  May 14, 2007
Channel 4 News,Patients prescribed donepezil, rivastagmine and galantamine were found to have 70% fewer of the proteins linked to brain plaques associated with Alzheimer's

Eisai Limited: Time is of the essence  -  May 15, 2007
InTheNews.co.uk,The cholinesterase drugs donepezil (made by Eisai and sold under the name Aricept), rivastagmine and galantamine work by protecting the communication

Alzheimer's Society: "Unethical" for drugs to be denied  -  May 15, 2007
InTheNews.co.uk,The cholinesterase drugs donepezil, rivastagmine and galantamine work by protecting the communication process between brain cells from plaques and tangles

Date set for court challenge to NICE on Alzheimer's  -  May 9, 2007
Pharma Times (subscription),Alzheimer's should have access to the only effective drugs to treat the debilitating illness on the NHS, such as Eisai and Pfizer's Aricept (donepezil).

Alzheimer's Drug Moving Ahead Positively, Boosting Elan's Stock  -  May 21, 2007
BioWorld Online,Drugs currently indicated for Alzheimer's include Aricept (donepezil, from Pfizer Inc.), Exelon (rivastigmine, from Novartis AG), Cognex (tacrine,

Japan's Eisai soars on back of healthy sales and patent win  -  May 16, 2007
Pharma Times (subscription),The rises were driven once again by Aricept (donepezil) for Alzheimer's disease which had sales of 252.9 billion yen, a leap of 28.7%.

EPIX Announces 2007 First Quarter Financial Results  -  May 8, 2007
PharmaLive.com (press release),A Phase 2a study of PRX-03140 alone and in combination with donepezil (Aricept(R)) is currently underway, with data expected at the end of 2007.

From the analyst's couch: Therapies for Alzheimer's disease  -  May 4, 2007
Nature.com (subscription),The five drugs currently on the market — the cholinesterase inhibitors donepezil (Aricept; Eisai/Pfizer), rivastigmine (Exelon; Novartis),

Invited commentary on ... Cardiovascular monitoring with ...  -  Apr 30, 2007
Adv Psychiatric Treat (subscription)...comprehensive and properly evidence-based review on cardiovascular screening when using the three licensed acetylcholinesterase inhibitors (donepezil,

Psychiatric Sequelae of Traumatic Brain Injury: A Case Report  -  May 2, 2007
Am J Psychiatry (subscription)Agents found to enhance specific types of cognitive functioning include methylphenidate for attention and speed of cognitive processing, donepezil to

Eisai pulls European application for Aricept new use  -  Apr 16, 2007
Pharma Times (subscription),The Tokyo-based company was asked by the European Medicines Agency to provide additional data showing that Aricept (donepezil) led to improvements in daily

NICE faces legal challenge  -  Mar 27, 2007
Healthcare Equipment and Supplies,The decision involves three drugs: donepezil; rivastigmine; and galantamine. NICE had proposed to restrict their use since March 2005 but it wasn’t until

Canadian Study Shows Treatment For Alzheimer's Disease Can ...  -  Apr 16, 2007
Medical News Today (press release),Verbal repetition in patients with Alzheimer's disease who receive donepezil. Int J Geriatr Psychiatry. 2006;21:426-431. 4 - Bourgeois M, Burgio L,

Posttraumatic Stress Disorder-Like Symptoms After Treatment With ...  -  Feb 16, 2007
Journal of Neuropsychiatry (subscription)The patient was started on a regimen of donepezil, 5mg/day. One month later, when no significant changes were seen, the dose of donepezil was increased to

Treatment of Apathy With Methylphenidate  -  Feb 16, 2007
Journal of Neuropsychiatry (subscription)He was being treated with a regimen of donepezil, 10mg/day, and bupropion, 75mg bid At initial intake, he was disheveled, lacked interest,

Campaigners back court challenge on Alzheimer's drug  -  Feb 7, 2007
Norwich Evening News,The watchdog ruled in 2005 that drugs including Aricept (donepezil), Exelon (rivastigmine) and Reminyl (galantamine) should not be prescribed for patients

Plane Crash Kills Renowned Alzheimer's Researcher  -  Feb 6, 2007
Associated Content,Those drugs are Tacrine (Cognex), donepezil (Aricept), rivastigmine (Exelon), galantamine (Razadyne), and memantine (Namenda).

Alzheimer's disease: physicians do not always practice what NICE ...  -  Feb 5, 2007
Pharmaceutical Business Review...and fall into two categories: acetycholinesterase inhibitors (AChEIs) including Aricept (donepezil), Exelon (rivastigmine) and Razadyne (galantamine),

Neurochem: excitement builds as Alzhemed phase III trial is completed  -  Feb 2, 2007
Pharmaceutical Business ReviewAlzhemed's positioning as a potentially disease-modifying treatment would be a clear advantage over Aricept (donepezil, Eisai/Pfizer), the current market

Eisai Announces Inovelon(R) Receives Marketing Authorization ...  -  Jan 28, 2007
Medical News Today (press release),Eisai is currently enhancing its neurology franchise which includes Aricept(R) (donepezil) for treatment of Alzheimer's disease and anti-epilepsy agent

In Vivo Evaluation of P-Glycoprotein Modulation of 8 PET ...  -  Jan 4, 2007
Journal of Nuclear Medicine (subscription)Results: In assay 1, CsA treatment increased both the uptake and the brain-to-blood ratio of 11 C-TMSX, 11 C-MPDX, 11 C-flumazenil, and 11 C-donepezil among

Battle for Alzheimer's drugs goes to court  -  Jan 9, 2007
Telegraph.co.uk,In November, Nice ruled that three Alzheimer's drugs — donepezil (Aricept), galantamine (Reminyl) and rivastigimine (Exelon) — should not be used for new

New Drug Said To Be Effective In Helping Blacks With Alzheimer's ...  -  Dec 28, 2006
Atlanta Daily World,The study, led by Dr. Patrick Griffith of Meharry Medical College in Nashville, revealed that a drug called donepezil-more commonly known as the brand name

Eisai takes NICE to High Court over Alzheimer's review  -  Jan 8, 2007
Pharma Times (subscription),Eisai and Pfizer, its co-promotion partner for Aricept (donepezil), noted that the former firm has formally applied to the High Court for permission to

Few Alzheimer's treatments now and no cure ... yet  -  Dec 29, 2006
Daily Home Online,The most commonly prescribed is donepezil, which is more commonly known as Aricept. The FDA approved the drug in 1996. More than 3.8 million people have

Cup of tea may help boost memory  -  Dec 25, 2006
Kazinform,However, many of the drugs currently available, such as donepezil, have unpleasant side effects and the medical profession is keen to find alternatives.

EPIX Pharmaceuticals Initiates Phase 2a Clinical Trial in Patients ...  -  Dec 5, 2006
PharmaLive.com (press release),Acetylcholinesterase (AChE) inhibitors, a class of drugs approved for the treatment of Alzheimer's disease that includes donepezil, are active in patients

Treatment of Intractable Hiccups With Olanzapine Following Recent ...  -  Nov 29, 2006
Journal of Neuropsychiatry (subscription)Persistent encephalopathy and functional impairments were then treated with a regimen of donepezil, 5 mg daily; this treatment improved these problems

Cup of tea may help boost memory  -  Dec 25, 2006
Kazinform,However, many of the drugs currently available, such as donepezil, have unpleasant side effects and the medical profession is keen to find alternatives.

NICE SCIE guideline to improve care of people with dementia  -  Dec 7, 2006
Xagena.it,It recommends that Donepezil, Galantamine and Rivastigmine may be offered to a small number of patients with dementia with Lewy bodies if these symptoms are

Epix launches midstage trial for Alzheimer's treatment  -  Dec 5, 2006
Bizjournals.com,...on Tuesday that it had launched the trial to test PRX-03140 on its own and in combination with the drug donepezil to treat mild Alzheimer's disease.

Behavior-Based Interventions to Enhance Cognitive Functioning and ...  -  Dec 19, 2006
Journal of American Medical Association (subscription),Vitamin E and donepezil for the treatment of mild cognitive impairment. N Engl J Med. 2005;352:2379-2388. FREE FULL TEXT. 10. Shumaker SA, Legault C,

Federal scientist faces prison over conflict of interest charge  -  Dec 6, 2006
OutSourcing-Pharma.com,Pfizer market Alzheimer's drug Aricept (donepezil HCl). The drug is thought to work by reducing the breakdown of the acetylcholine (Ach), a neurotransmitter

Market Report -- In Play (WIRES)  -  Dec 5, 2006
MSN Money...of a Phase 2a clinical trial to further evaluate PRX-03140 as monotherapy and in combination with donepezil for the treatment of Alzheimer's disease.

We're dopes not to OK marijuana  -  Dec 1, 2006
Seattle Post Intelligencer,...primary marker for Alzheimer's disease -- in a manner "considerably superior" to government-approved Alzheimer's drugs such as donepezil and tacrine.

APNS Partners With Lilly For Early Stage Alzheimer's Work  -  Nov 28, 2006
BioWorld Online,Most of the existing drugs - including top-selling Aricept (donepezil, from Eisai Co. Ltd. and Pfizer Inc.), which recorded worldwide sales of $1.7 billion

Donepezil Improves Cognition in Severe Alzheimer's Disease ...  Sep 7, 2006
GLASGOW, UK -- September 6, 2006 -- The selective acetylcholine esterase inhibitor donepezil provides greater improvements in cognition and global function ... -DG News

Memantine Can Provide Behavioural Mood and Psychosis Benefits in ...  Sep 22, 2006
...to evaluate the effects on NPI seen in a previously reported 24-week study of patients with moderate to severe AD taking concomitant donepezil treatment and ... -DG News

Pfizer and TransTech enter deal that’s all the RAGE  Sep 21, 2006
Treatments include the Cholinesterase inhibitors including donepezil (Aricept), galantamine (Reminyl) and rivastigmine (Exelon) and NMDA receptor antagonists ... -LabTechnologist.com

Are All Dementias Alzheimer's?  Sep 18, 2006
These acetylcholisterase inhibitors, namely galantamine, rivastigmine, and donepezil, are aimed at improving the cholinergic functioning in the brain by ... -American Chronicle

Ligand Sells More Products: $205M For Cancer Portfolio  Sep 8, 2006
...she said. Eisai's flagship product is Aricept (donepezil), the world's leading therapy for Alzheimer's disease. An acetylcholinesterase ... -BioWorld Online

Big Pharma holds drug and advocacy groups hostage  Sep 1, 2006
...on the sheet handed out by the pharmacist: how to take the drug, expected side effects and so on for drugs such as Aricept (donepezil), Exelon (rivastigmine ... -Common Ground.ca

I Love Coffee, I Love Tea  Sep 4, 2006
However, many of the drugs currently available, such as donepezil, have unpleasant side effects and the medical profession is keen to find alternatives. ... -50 Connect

Alzheimer's disease: THC inhibits the enzyme acetylcholinesterase  Aug 25, 2006
Propidium, we also found that THC was considerably more effective than two of the approved drugs for Alzheimer's disease treatment, Donepezil ( Aricept ) and ... -Xagena.it

Your health  Aug 24, 2006
...patients: 1. Cholinesterase inhibitors including donepezil (Aricept), galantamine (Reminyl) and rivastigmine (Exelon). 3. Neuroleptics ... -Sur

EPIX Pharmaceuticals Initiates Phase 2a Clinical Trial in Patients ...  -  Dec 5, 2006
PharmaLive.com (press release),Acetylcholinesterase (AChE) inhibitors, a class of drugs approved for the treatment of Alzheimer's disease that includes donepezil, are active in patients

NICE SCIE guideline to improve care of people with dementia  -  Dec 7, 2006
Xagena.it,It recommends that Donepezil, Galantamine and Rivastigmine may be offered to a small number of patients with dementia with Lewy bodies if these symptoms are

Treatment of Intractable Hiccups With Olanzapine Following Recent ...  -  Nov 29, 2006
Journal of Neuropsychiatry (subscription)Persistent encephalopathy and functional impairments were then treated with a regimen of donepezil, 5 mg daily; this treatment improved these problems

Epix launches midstage trial for Alzheimer's treatment  -  Dec 6, 2006
Charlotte Business Journal,...on Tuesday that it had launched the trial to test PRX-03140 on its own and in combination with the drug donepezil to treat mild Alzheimer's disease.

Drugs watchdog faces legal review  -  Nov 16, 2006
BBC News,NICE ruled NHS patients with newly diagnosed, mild Alzheimer's disease should not be prescribed donepezil, rivastigmine and galantamine.

NICE to allow scrips for mild Alzheimer's  -  Nov 23, 2006
Therapeutics Daily (subscription) (press release),The clinical guideline on dementia says that donepezil, galantamine and rivastigmine can be given to patients with mild Alzheimer's if symptoms cause

Will science or money control dementia drugs?  -  Nov 19, 2006
Scotsman,These drugs - Aricept (donepezil), Exelon (rivastigmine) and Reminyl (galantamine)... The full article contains 952 words and appears in The Scotsman

Challenge to dementia drug ruling  -  Nov 16, 2006
ic SouthLondon.co.uk,...sufferers with early or late-stage Alzheimer's disease should not have access to Aricept (donepezil), Reminyl (galantamine) or Exelon (rivastigmine).

Drugs watchdog in legal wrangle  -  Nov 17, 2006
Politics.co.uk,...for Clinical Excellent (Nice) ruling that patients with mild Alzheimer's should not be prescribed donepezil (or aricept), reminyl and exelon on the NHS.

'Disgraceful' ruling sparks angry protest  -  Nov 17, 2006
ic CheshireOnline,The Alzheimer's Society last month failed to overturn NICE proposals on dementia drugs donepezil, reminyl, memantine and exelon.

Alzheimer's drug decision challenge  -  Nov 17, 2006
Healthcare Today,NICE has ruled NHS patients with newly diagnosed, mild Alzheimer's disease should not be prescribed the drugs, which include donepezil, rivastigmine and

Challenge to dementia drug ruling  -  Nov 16, 2006
Bradford Telegraph,...that sufferers with early or late-stage Alzheimer's disease should not have access to Aricept (donepezil), Reminyl (galantamine) or Exelon (rivastigmine).

Experts Support The Continual Prescribing Of Ebixa (memantine) For ...  -  Nov 22, 2006
Medical News Today (press release),Implementation of the NICE guidance on donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease: Position statement by

NICE SCIE Guideline to Improve Care of People with Dementia  -  Nov 22, 2006
PharmaLive.com (press release),The guideline incorporates the Institute's recommendation that donepezil, galantamine and rivastigmine should only be prescribed for people with moderate

Federal scientist faces prison over conflict of interest charge  -  Dec 6, 2006
OutSourcing-Pharma.com,Pfizer market Alzheimer's drug Aricept (donepezil HCl). The drug is thought to work by reducing the breakdown of the acetylcholine (Ach), a neurotransmitter

Market Report -- In Play (WIRES)  -  Dec 5, 2006
MSN Money...of a Phase 2a clinical trial to further evaluate PRX-03140 as monotherapy and in combination with donepezil for the treatment of Alzheimer's disease.

We're dopes not to OK marijuana  -  Dec 1, 2006
Seattle Post Intelligencer,...primary marker for Alzheimer's disease -- in a manner "considerably superior" to government-approved Alzheimer's drugs such as donepezil and tacrine.

APNS Partners With Lilly For Early Stage Alzheimer's Work  -  Nov 28, 2006
BioWorld Online,Most of the existing drugs - including top-selling Aricept (donepezil, from Eisai Co. Ltd. and Pfizer Inc.), which recorded worldwide sales of $1.7 billion

Eisai Inc. Breaks Ground for New Oncology Facility in Research ...  -  Nov 24, 2006
Expansion Management,The new facility will complement the existing 190000 square foot structure, which is devoted to manufacturing Aricept (donepezil hydrochloride tablets) and

Eisai Recieves Positive Opinion For Inovelon(R) Marketing ...  -  Nov 23, 2006
Medical News Today (press release),Eisai is currently enhancing its neurology franchise which includes Aricept(R)(donepezil) for treatment of Alzheimer's disease and anti-epilepsy agent

Dementia care should be improved  -  Nov 22, 2006
Healthcare Today,...over its decision to deny people with early or late-stage Alzheimer's disease access to donepezil (Aricept), galantamine (Reminyl) and rivastigmine.

Call for improved dementia care  -  Nov 21, 2006
BBC News,The watchdog is facing a legal challenge over its decision to deny people with early or late-stage Alzheimer's disease access to donepezil (Aricept),

Campaign attacks health watchdog  -  Nov 21, 2006
Yorkshire Post Today,But the watchdog is facing a legal challenge over its decision to deny early or late-stage Alzheimer's disease patients Aricept (donepezil),

Eisai Recieves Positive Opinion for Inovelon® Marketing ...  -  Nov 21, 2006
PipelineReview.com (press release),Eisai is currently enhancing its neurology franchise which includes Aricept® (donepezil) for treatment of Alzheimer's disease and anti-epilepsy agent

Furore over who gets Alzheimer's drug in the UK  -  Nov 20, 2006
News-Medical.net,The issue involves four drugs, the most popular of which is being Aricept, (donepezil), which is made by Eisai and Pfizer. Though the drugs do not represent

Secrecy over NHS drug rationing faces court challenge  -  Nov 17, 2006
Times Online,NICE’s rejection of three Alzheimer’s drugs — donepezil (Aricept), galantamine (Reminyl) and rivastigmine (Excelon) — provoked widespread anger among

Alzheimer's Drug Restriction To Be Challenged In Court  -  Nov 18, 2006
Medical News Today,After the National Institute for Clinical Excellence (NICE), UK, recommended restricting the use of Alzheimer's drug, Aricept (donepezil), Eisai and Pfizer,

Secrecy over NHS drug rationing faces court challenge  -  Nov 16, 2006
Times Online,NICE’s rejection of three Alzheimer’s drugs, donepezil (Aricept), galantamine (Reminyl) and rivastigmine (Excelon) provoked widespread anger among patients,

NICE Subject to Potential Judicial Review Following Unfair and ...  -  Nov 17, 2006
PharmaLive.com (press release),17, 2006-Eisai Limited, the licence holder of Aricept® (donepezil hydrochloride) and Pfizer Limited, its co-promotion partner, announced today that Eisai

New hope in the Alzheimer's drugs battle  -  Nov 17, 2006
Norwich Evening News,Alzheimer's should not have access to Aricept (donepezil), Reminyl (galantamine) or Exelon (rivastigmine) - prompting today's protest in the city.

Eisai Inc. Breaks Ground for New Oncology Facility in Research ...  -  Nov 13, 2006
Drug Newswire (press release),The new facility will complement the existing 190000 square foot structure, which is devoted to manufacturing Aricept(R) (donepezil hydrochloride tablets)

Eisai Inc. Breaks Ground for New Oncology Facility in Research ...  -  Nov 13, 2006
Pharmaceutical Processing,The new facility will complement the existing 190000 square foot structure, which is devoted to manufacturing Aricept® (donepezil hydrochloride tablets) and

Envisioning Better Approaches for Dementia Care  -  Nov 20, 2006
Annals of Internal MedicineCourtney C, Farrell D, Gray R, Hills R, Lynch L, Sellwood E. Long-term donepezil treatment in 565 patients with Alzheimer's disease (AD2000): randomised

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