Recent news on Etanercept

'Mini-antibodies' in first-ever clinical trials  -  May 23, 2007
DrugResearcher.com,Finally, Amgen and Wyeth's Enbrel (etanercept) approved for use against arthritis, spondylitis and psoriasis. Together, these drugs had combined global

Thalidomide Provides a Durable Response and Survival Benefit ...  -  May 22, 2007
DG NewsThe best survival rates occurred in patients who received thalidomide and etanercept, but these patients may have had lower-risk disease,

Alternative Financings Provide Biotechs With More Options  -  May 18, 2007
BioWorld Online,Earlier this month, Drug Royalty bought a stake in ex-North American sales of Enbrel (etanercept, Amgen Inc. and Wyeth Pharmaceuticals Inc.) from

Data Show ENBREL Significantly Improved Nail Psoriasis in Patients ...  -  May 18, 2007
campus med,...in moderate to severe plaque psoriasis patients, ENBREL(R) (etanercept) reduced the severity of nail psoriasis by more than 28 percent at 12 weeks and

Drug Royalty Corporation (DRC) Announces Acquisition Regarding Enbrel  -  May 10, 2007
PharmaLive.com (press release),ENBREL(R) (etanercept) is indicated for reducing the signs and symptoms of rheumatoid arthritis, polyarticular-course juvenile rheumatoid arthritis,

Abbott's novel psoriasis biologic shows promise  -  May 10, 2007
In-PharmaTechnologist.com,Amevive (alefacept), the first biologic treatment approved for treating moderate to severe psoriasis, Enbrel (etanercept), and Raptiva (efalizumab).

Drug Royalty Corporation (DRC) Announces Acquisition Regarding ...  -  May 9, 2007
CNW Telbec (Communiqués de presse),...<< About ENBREL(R) >> ENBREL(R) (etanercept) is indicated for reducing the signs and symptoms of rheumatoid arthritis, polyarticular-course juvenile

Ariad Reports First Quarter 2007 Results and Provides Update on ...  -  May 8, 2007
PharmaLive.com (press release),6410516 are invalid and that Amgen has not infringed any of the claims of the patent based on activities related to Enbrel(R) (etanercept) and Kineret(R)

Cimzia's setback paves way for other TNF inhibitors in Crohn's disease  -  Apr 30, 2007
Nature.com (subscription),Enbrel (etanercept), marketed by Thousand Oaks, California–based Amgen, Madison, New Jersey–based Wyeth, and Osaka, Japan–based Takeda,

Inflammation, Asthma, and Tumor Necrosis Factor-alpha  -  Apr 24, 2007
Medscape (subscription)In an open-label trial of etanercept (soluble TNF-alpha receptor) for 3 months, treated patients had some improvement in measures of airflow, symptom scores

French Guidelines for Pretreatment Screening Inadequate to ...  -  Apr 10, 2007
DG News...with the soluble receptor protein (etanercept), although further analyses will be needed to determine the significance and extent of these outcomes.

Amgen posts strong results after Aranesp relief  -  Apr 24, 2007
BiopharmaReporter.com,Sales of rheumatology and psoriasis drug Enbrel (etanercept) increased 11 per cent to $730m - despite a slower growth in the US due to increased competition

Amgen's First Quarter 2007 Revenue Increased 15 Percent to $3.7 ...  -  Apr 23, 2007
Genetic Engineering News (press release),Sales of Enbrel(R) (etanercept) increased 11 percent in the first quarter to $730 million versus $658 million during the same period in 2006 reflecting an

Wyeth earnings get a boost in Q1  -  Apr 20, 2007
Pharma Times (subscription),...and the arthritis therapy Enbrel (etanercept), which jumped 33% to $445 million (excluding the USA and Canada, where it is sold by Amgen).

Ariad and Amgen in battle over biotech patent  -  Apr 18, 2007
BiopharmaReporter.com,...patents - No 6410516 - was invalid and that it had not infringed any part of it with its arthritis drugs Enbrel (etanercept) and Kineret (anakinra).

ARIAD Files Patent Infringement Claim Against Amgen and Wyeth  -  Apr 15, 2007
ag-IP-news Agency,6410516 (the '516 Patent) are invalid and that Amgen has not infringed any of the claims of the patent based on activities related to Enbrel (etanercept)

XOMA Announces Clinical Trial Plans for XOMA 052 in Type 2 Diabetes  -  Apr 12, 2007
PipelineReview.com (press release),..."Having participated in the development of other biological drugs such as rituximab, etanercept and anakinra, I can say that I am excited about the

A wonder drug beat my teenage arthritis  -  Apr 10, 2007
Daily Mail,There are three different anti-TNF drugs on the market at present: Enbrel (etanercept), Humira (adalimumab) and Remicade (infliximab), delivered either by

Billion dollar babies—biotech drugs as blockbusters  -  Apr 3, 2007
Nature.com (subscription),Amgen's Enbrel (etanercept), the most successful of the three anti-TNFs currently in the market, was first approved in 1998 to treat active rheumatoid

Wyeth buys out Takeda's 20% stake in Japanese unit  -  Apr 4, 2007
Pharma Times (subscription),The two firms currently co-promote the rheumatoid arthritis drug Enbrel (etanercept), and their collaboration "is central to making Japan one of the

Ask the Pharmacist  -  Feb 20, 2007
MLive.com,He also shared that she took Enbrel (etanercept), another injectable drug for inflammatory joint pain. Enbrel is commonly prescribed for rheumatic pain and

The problem with treating spondylarthritis with anti-TNF strategies  -  Jan 31, 2007
PressZoom (press release),From week 12 to week 25, the mice were treated twice weekly with etanercept, in a strength comparable to standard dosage for human patients, or a placebo.

Switching TNF-alpha blockers can be effective for rheumatoid ...  -  Feb 14, 2007
Therapeutics Daily (subscription) (press release),The analysis involved 6739 patients who started new anti-TNF treatment: 876 on adalimumab, 2826 on etanercept and 3037 on infliximab. During a mean of 15 .

New Treatments Fight GVHD In Bone Marrow Transplant Patients  -  Feb 6, 2007
Medical News Today (press release),The researchers are particularly excited about the use of etanercept, a drug that is commonly used to reduce the inflammation of rheumatoid arthritis,

Prevnar, Enbrel and Effexor drive Wyeth growth  -  Jan 31, 2007
Pharma Times (subscription),Back to the drugs and Enbrel (etanercept) climbed 40% to $416 million outside North America, where Wyeth has exclusive marketing rights, while Prevnar

Aranesp Data Eclipse Amgen's Fourth-Quarter Revenue Growth  -  Jan 26, 2007
BioWorld Online,North American sales of Enbrel (etanercept) increased 18 percent over last year to $792 million. And combined worldwide sales of Amgen's neutropenia drugs,

A New Jump Start For Aging Blood Vessels  -  Jan 3, 2007
Medical News Today (press release),Csiszar and collegues treated aged rats with etanercept to test the hypothesis that anti-TNFa treatment exerts vasculoprotective effects in aging.

Vasculoprotective Effects of Anti-Tumor Necrosis Factor- Treatment ...  -  Jan 17, 2007
Am J Pathology (subscription)To test the hypothesis that anti-TNF- treatment exerts vasculoprotective effects in aging, aged (29 months old) F344 rats were treated with etanercept (1

New way to keep blood vessels young?  -  Dec 29, 2006
United Press InternationalThey used the rheumatoid arthritis drug etanercept -- sold as Enbrel -- that binds and inactivates circulating TNFa in a series of experiments with aged

A 24-Year-Old Woman with Systemic Lupus Erythematosus, Seizures ...  -  Dec 20, 2006
New England Journal of Medicine (subscription),She had been treated continuously with corticosteroids, with the addition of methotrexate, azathioprine, mycophenolate, leflunomide, and etanercept at

Research and Markets: Gain an Insight into the Financial ...  -  Dec 20, 2006
PharmaLive.com (press release),Enbrel (etanercept) is a soluble tumour necrosis factor which has potential in several inflammatory diseases mediated by excess TNF.

Wyeth kicks off CMO agreement with Crucell  -  Dec 20, 2006
OutSourcing-Pharma.com,The company currently manufactures three products at the site, Enbrel (etanercept) for the treatment of moderately to severely active rheumatoid arthritis,

Research and Markets: Gain an Insight into the Financial ...  -  26 Dec 2006
PharmaLive.com (press release),Enbrel (etanercept) is a soluble tumour necrosis factor which has potential in several inflammatory diseases mediated by excess TNF.

Pfizer's Celebrex treats Juvenile Rheumatoid Arthritis  -  26 Dec 2006
SpiritIndia,Amgen (NASDAQ: AMGN) announced Enbrel (R) (etanercept) is the first biologic with published data to show sustained improvements in multiple efficacy

To keep colds at bay, stock up on sneakers  -  26 Dec 2006
Nashua Telegraph (subscription),...including the so-called biologic medications etanercept (Enbrel) and infliximab (Remicade). Blood and lymphatic cancers were diagnosed in 69 people;

Randomized phase 2 trial of anti-tumor necrosis factor therapy for ...  -  Dec 7, 2006
Am J Clin Nutr (subscription),Objective: The main aim of this study was to investigate the effect of etanercept, a synthetic soluble TNF receptor, on body composition in patients with

Protalex arthritis drug equal to standard medication  -  Dec 1, 2006
Pharmaceutical Business ReviewIn the studies, reduction in clinical scores and pathology with PRTX-100 were equivalent to the suppression seen in mice treated with etanercept.

A 24-Year-Old Woman with Systemic Lupus Erythematosus, Seizures ...  -  Dec 20, 2006
New England Journal of Medicine (subscription),She had been treated continuously with corticosteroids, with the addition of methotrexate, azathioprine, mycophenolate, leflunomide, and etanercept at

Wyeth kicks off CMO agreement with Crucell  -  Dec 20, 2006
OutSourcing-Pharma.com,The company currently manufactures three products at the site, Enbrel (etanercept) for the treatment of moderately to severely active rheumatoid arthritis,

The Impact Of Immunosuppressive Medications On Cardiovascular ...  -  Dec 1, 2006
Medical News Today (press release),...including the interleukin-1 receptor antagonist anakinra as well as the three TNFá blockers, adalimumab, etanercept, and infliximab.

Cytotoxic and Glucocorticoid Agents Increase CV Risk in Rheumatoid ...  -  Nov 29, 2006
Medscape (subscription)RA medications studied included methotrexate monotherapy (reference exposure), tumor necrosis factor–alpha antagonists (adalimumab, etanercept,

For RA Cardioprotection, Biologics Found Equal to Methotrexate  -  Nov 29, 2006
MedPage Today,Biologic agents Humira (adalimumab), Enbrel (etanercept), Remicade (infliximab) and Kineret (anakinra) as a group carried the same risk as methotrexate

Risk of Serious Infections and Malignancies With Anti-TNF Antibody ...  Nov 7, 2006
The exclusion of etanercept from our review was based on the biological considerations discussed in the article. Meta-analyses require ... -Journal of American Medical Association (subscription), New Data Reinforce Safety Profile Of ENBREL (Etanercept) For ...  Oct 9, 2006
There is good news for psoriasis patients as the latest study confirming the established safety profile of ENBRELâ„¢ (etanercept) for up to 2.5 years , was ... -Medical News Today (press release), New Data Reinforce Safety Profile of ENBREL(R) (etanercept) in ...  Oct 10, 2006
There was good news for psoriasis patients today as the latest study confirming the established safety profile of ENBREL(R) (etanercept) for up to 2.5 years[1 ... -Drug Newswire (press release), Arthritis drugs not as risky as first thought  Nov 8, 2006
Matteson's team is now looking at a third drug in the same class, which they are also concerned about, Enbrel (Amgen), known generically as etanercept. ... -News-Medical.net, Drug Researchers Admit Failure to Disclose Ties to Industry  Nov 8, 2006
Also noted in the letter was the fact that Dr. Bongartz received a $25,000 education fellowship from Amgen, who markets Enbrel, or etanercept, a third type of ... -Newsinferno.com, Investigation, Explanation, and Apology for Incomplete and ...  Nov 7, 2006
...currently negotiating a service agreement with Wyeth to use our meta-analysis method to study malignancy risk associated with the use of etanercept, which is ... -Journal of American Medical Association (subscription), Psoriasis Fact Sheet  Oct 29, 2006
Newer biological therapies, such as etanercept, have been approved recently to treat moderate to severe forms of the disease. A ... -Medical News Today (press release), Singapore Joins The World In Advancing Understanding Of Chronic ...  Oct 29, 2006
In recent years, the arrival of biologic treatment agents, such as etanercept, has revolutionised psoriasis treatment. Etanercept ... -Medical News Today (press release), New Study Reveals Postcode Lottery For Rheumatoid Arthritis ...  Oct 11, 2006
...[4] Anti-TNF therapies include etanercept and infliximab. NICE has approved both for the treatment of RA, and etanercept for JIA only. ... -eMaxHealth.com, Roche Legal Worries Aside, Amgen Posts Solid Earnings  Oct 24, 2006
Enbrel (etanercept), the rheumatoid arthritis drug that sold $2.5 billion last year, proved the only dark spot on earnings this time around, totaling $705 ... -BioWorld Online, No need to fear it  Oct 28, 2006
...immune cells. Several are available — etanercept, infliximab and efaluzimab to name only a few that have been introduced. They ... -Hindu, Amgen's Third Quarter 2006 Adjusted Earnings Per Share, Excluding ...  Oct 23, 2006
North American sales of Enbrel(R) (etanercept) increased 6 percent in the third quarter to $705 million versus $668 million during the same period in 2005. ... -Genetic Engineering News (press release), Abatacept Plus Etanercept Should Not Be Used for Rheumatoid ...  Sep 5, 2006
September 5, 2006 — The combination of abatacept plus etanercept increased serious adverse events in patients with rheumatoid arthritis (RA) and therefore ... -Medscape (subscription)

DMARD Use in Rheumatoid Arthritis Increases Risk for Tuberculosis  Aug 29, 2006
However, according to the authors of the current study, whether the newer biological DMARDs (such as infliximab, etanercept, and anakinra) are associated with ... -Medscape (subscription)

Tumor Necrosis Factor Blockers May Not Cause Cancer After All  Aug 31, 2006
...lymphoma prompted the Food and Drug Administration to mandate adding a cancer risk warning to the labels of three TNF blockers: etanercept (Enbrel), infliximab ... -eMaxHealth.com

Similar Risk of Cancer in Patients Treated with Two Types of ...  Sep 6, 2006
...arthritis, risk of cancer was no higher among those treated with anti-tumor necrosis factor (anti-TNF) agents such as Enbrel® (etanercept) than among those ... -Cancer Consultants

Study briefs, 9/12: Cancer, asthma risk, pregnancy  Sep 15, 2006
15 percent were taking a different type of disease-modifying anti-rheumatic drug (DMARD), including the so-called biologic medications etanercept (Enbrel) and ... -Lincoln Journal Star

Wyeth/Amgen's Enbrel to Achieve Blockbuster Status by 2010 for the ...  Sep 11, 2006
...one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Wyeth/Amgen's Enbrel (etanercept) will achieve ... -PharmaLive.com

Rheumatoid Arthritis Drugs May Not Raise Cancer Risk  Aug 31, 2006
He was not involved in this study. TNF blockers include infliximab (Remicade), etanercept (Enbrel), and adalimumab (Humira). The ... -Forbes

Arthritis Drugs May Not Be Complicit in Cancer Risks  Aug 31, 2006
RA patients ages 65 and older with RA, 1,152 of whom had received a prescription for a DMARD, either the TNF-α inhibitors Enbrel (etanercept, 64%), Remicade ... -MedPage Today

Big Pharma holds drug and advocacy groups hostage  Sep 1, 2006
Professional� letter of January 13, 2006, warning of “Hepatitis B Reactivation� associated with drugs like Enbrel (etanercept), Humira (adalimumab) and ... -Common Ground.ca

TNF level predicts who will develop deadly complication after bone ...  Aug 28, 2006
We are currently conducting a clinical trial using one of these drugs, Etanercept ( Enbrel ), in clinical trials to see if it can prevent or treat GVHD, " says ... -Xagena.it

Biologics Define New Standard of Therapy in Psoriasis  Sep 7, 2006
Systemic anti-TNF biologics etanercept followed by infliximab, adalimumab and certolizumab pegol have raised the level of efficacy in an unprecedented manner ... -PharmaLive.com

Randomized phase 2 trial of anti-tumor necrosis factor therapy for ...  -  12 Dec 2006
Am J Clin Nutr (subscription),Objective: The main aim of this study was to investigate the effect of etanercept, a synthetic soluble TNF receptor, on body composition in patients with

Get the latest news direct to your desktop  -  12 Dec 2006
PipelineReview.com (press release),Announced that Enbrel(R) (etanercept) is the first biologic with published data to show improvements in multiple measures of efficacy that were sustained in

ACR: No Cancer Link Found with New Rheumatoid Arthritis Agents  -  12 Dec 2006
MedPage Today,...seen in some clinical trials of the medications, added a warning on the labels of Remicade (inflixumab), Enbrel (etanercept), and Humira (adalimumab).

Rheumatoid Arthritis :: Enbrel first biologic with up to 9 years ...  -  12 Dec 2006
SpiritIndia,Amgen (NASDAQ: AMGN) announced Enbrel (R) (etanercept) is the first biologic with published data to show sustained improvements in multiple efficacy

Enbrel First Biologic With Up To 9 Years Rheumatoid Arthritis Safety  -  12 Dec 2006
eMaxHealth.com,Amgen today announced that Enbrel (etanercept) is the first biologic with published data to show improvements in multiple measures of efficacy that were

Enbrel first biologic with up to 9 years rheumatoid arthritis ...  -  12 Dec 2006
EurekAlert (press release),...(etanercept) is the first biologic with published data to show improvements in multiple measures of efficacy that were sustained in rheumatoid arthritis

Rheumatoid arthritis drugs do not increase cancer risk  -  12 Dec 2006
South Asian Women's Forum,Typically, however, biologics such as adalimumab, etanercept, infliximab, anakinra and abatacept, are used only as a second line therapy because of their

Data Shows Enbrel Provides Sustained Clinical Improvements for ...  -  12 Dec 2006
PharmaLive.com (press release),...phase 4 extension study showed that patients with ankylosing spondylitis (AS) who received treatment with Enbrel(R) (etanercept) experienced sustained

NEWS RELEASE  -  12 Dec 2006
Financial News USA (press release),Amgen (NASDAQ:AMGN) recently announced that Enbrel® (etanercept) is the first biologic with published data to show improvements in multiple measures of

Data Shows ENBREL Provides Sustained Clinical Improvements for ...  -  12 Dec 2006
Business Wire (press release),Enbrel ® (etanercept) experienced sustained improvement in signs and symptoms, spinal mobility and physical function over 148 to 160 weeks of therapy.

Protalex arthritis drug equal to standard medication  -  Dec 1, 2006
Pharmaceutical Business ReviewIn the studies, reduction in clinical scores and pathology with PRTX-100 were equivalent to the suppression seen in mice treated with etanercept.

Waiting list slashed  -  Nov 23, 2006
Bolton News,New wonder-drugs, etanercept and adalimumab, which produce a protein that reduces inflammation in the joints, are now available in the borough - but only 25

Amgen presents Ph IV data on Enbrel  -  Nov 13, 2006
Therapeutics Daily (subscription) (press release),Phase IV extension study showed that patients with ankylosing spondylitis who received Enbrel (etanercept) experienced sustained improvement in signs

To keep colds at bay, stock up on sneakers  -  Dec 2, 2006
Nashua Telegraph (subscription),...including the so-called biologic medications etanercept (Enbrel) and infliximab (Remicade). Blood and lymphatic cancers were diagnosed in 69 people;

The Impact Of Immunosuppressive Medications On Cardiovascular ...  -  Dec 1, 2006
Medical News Today (press release),...including the interleukin-1 receptor antagonist anakinra as well as the three TNFá blockers, adalimumab, etanercept, and infliximab.

Cytotoxic and Glucocorticoid Agents Increase CV Risk in Rheumatoid ...  -  Nov 29, 2006
Medscape (subscription)RA medications studied included methotrexate monotherapy (reference exposure), tumor necrosis factor–alpha antagonists (adalimumab, etanercept,

For RA Cardioprotection, Biologics Found Equal to Methotrexate  -  Nov 29, 2006
MedPage Today,Biologic agents Humira (adalimumab), Enbrel (etanercept), Remicade (infliximab) and Kineret (anakinra) as a group carried the same risk as methotrexate

Enbrel Provides Sustained Clinical Improvements for People With ...  -  Nov 20, 2006
DG News...multinational, phase 4 extension study showed that patients with ankylosing spondylitis (AS) who received treatment with Enbrel (etanercept) experienced

Enbrel First Biologic With Up To 9 Years Rheumatoid Arthritis ...  -  Nov 18, 2006
Medical News Today (press release),On 13-Nov-2006 Amgen (NASDAQ: AMGN) announced that Enbrel (etanercept) is the first biologic with published data to show improvements in multiple measures

No Increase in Overall Cancer Rate Found Among Rheumatoid ...  -  Nov 16, 2006
DG NewsBiologics agents included in the study were adalimumab, etanercept and infliximab. Dr. Wolfe and colleagues studied data from a large US registry of RA

Ankylosing Spondylitis :: Enbrel provides sustained clinical ...  -  Nov 13, 2006
SpiritIndia,Amgen (NASDAQ: AMGN) announced patients with ankylosing spondylitis who received treatment with Enbrel (R) (etanercept) experienced sustained improvement in

Enbrel provides long term relief for ankylosing spondylitis  -  Nov 13, 2006
South Asian Women's Forum,Enbrel (etanercept) experienced sustained improvement in signs and symptoms, spinal mobility and physical function over 148 to 160 weeks of therapy.

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