Recent news on Etoposide

Potent Peat  -  May 21, 2007
New Haven Register (subscription),Moreover, the chemotherapy agents taxol, vincristine, lapachol, etoposide, and many other drugs, were derived from plants.

Occult Testicular Teratoma Presenting With Solid Mesenteric Metastasis  -  Apr 25, 2007
Journal of Ultrasound in Medicine (subscription)The patient received adjuvant chemotherapy including bleomycin, etoposide, and cisplatin. On follow-up, he was free of recurrence or distant metastasis for

2007 BIO International Convention Exhibitor Profiles Continued, M ...  -  May 3, 2007
American Digital Networks (press release),We are active in cytotoxic APIs : vinorelbine, vinflunine, etoposide etc... We are also highly skilled in natural product extraction and purification.

Total Lymphoid Irradiation and Stem Cell Transplantion Very ...  -  Apr 5, 2007
Cancer Consultants (press release),The current study evaluated a regimen of TLI followed by high-dose etoposide, cyclophosphamide and carboplatin in 32 patients and high-dose chemotherapy

Occult Testicular Teratoma Presenting With Solid Mesenteric Metastasis  -  Apr 25, 2007
Journal of Ultrasound in Medicine (subscription)The patient received adjuvant chemotherapy including bleomycin, etoposide, and cisplatin. On follow-up, he was free of recurrence or distant metastasis for

High-Dose Bexxar with Stem Cell Support Effective in Elderly B ...  -  Apr 17, 2007
Cancer Consultants (press release),Bexxar has been added to a standard regime of high-dose BEAM (carmustine, etoposide, cytarabine and melphalan) with the infusion of autologous stem cells

Study Describes Action Of Estrogen In Protecting Bone  -  Mar 28, 2007
Medical News Today (press release),Both groups then were exposed for 24 hours to a drug called etoposide, a cancer chemotherapeutic drug that promotes apoptosis.

Data acquisition for the histoculture drug response assay in lung ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryWe examined chemosensitivities of the tissues to cisplatin, doxorubicin, mitomycin C, 5-fluorouracil, docetaxel, paclitaxel, etoposide, irinotecan,

Signs of lung cancer  -  Feb 6, 2007
Malaysia Star,In SCLC, dose-intensive combinations of cisplatin, vincristine, doxorubicin and etoposide are used, as are the standard doses of cyclophosphamide,

Pro-Pharmaceuticals Collaborates with Chemwerth to Scale-up ...  -  Feb 20, 2007
PharmaLive.com (press release),Cisplatin USP, Doxorubicin HCl USP, Epirubicin HCl EP, Etoposide USP, Fludarabine Phosphate, Gemcitabine HCl USP, Ifosfamide USP, Irinotecan HCl 3H2O,

Chemotherapy resistance and oncogene expression in non–small cell ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryMore intermediate plus extreme chemotherapy resistances occurred in aneuploid tumors to etoposide (53% vs 36%, P = .0002) and topotecan (48% vs 36%,

Poor-Prognosis Germ Cell Tumors: We Have Not Yet Crossed The ...  -  Feb 19, 2007
Medical News Today (press release),...cycles of BEP followed by 2 cycles of high dose chemotherapy with carboplatin, etoposide, and cyclophosphamide and autologous stem cell rescue on day 5.

Camptosar® Evaluated in Children with Relapsed or Refractory ...  -  Feb 14, 2007
Cancer Consultants (press release),Adriamycin® (doxorubicin), Actinomycin D® (dactinomycin), Vepesid® (etoposide), Platinol® (cisplatin), and Paraplatin® (carboplatin).

Dose-Intensive Chemotherapy with Stem Cell and Neupogen® Support ...  -  Feb 5, 2007
Cancer Consultants (press release),A randomized phase III study that intensified doses of ICE (ifosfamide, carboplatin, and etoposide) administered with autologous stem cell and Neupogen

Improving Outcomes in Lymphoma  -  Feb 5, 2007
Medscape (subscription)The Nordic Lymphoma Group [8] reported phase 2 study results of CHOEP (cyclophosphamide, doxorubicin, vincristine, etoposide, and prednisone) followed by

Dose-intensive Chemotherapy Improves Survival for Patients with ...  -  Feb 2, 2007
Cancer Consultants (press release),...carboplatin, and etoposide) improve median survival compared to standard doses of ICE in the treatment of small cell lung cancer (SCLC).

Intensive Chemotherapy Regimen Shows Promise for Germ Cell Tumors  -  Feb 1, 2007
Cancer Consultants (press release),...vincristine, bleomycin, and carboplatin, followed by one cycle of vincristin and bleomycin and three cycles of bleomycon, etoposide, and cisplatin.

Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial ...  -  Jan 30, 2007
PipelineReview.com (press release),...including topotecan, anthracyclines such as doxorubicin, gemcitabine, cyclophosphamide, vinorelbine, hexamethylmelamine, ifosfamide, and etoposide.

Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial ...  -  Jan 29, 2007
PR Newswire (press release),...hexamethylmelamine, ifosfamide, and etoposide. Phase 2 Clinical Trial Design The clinical trial will evaluate two dosing schedules of glufosfamide,

An innovation in chemo  -  Jan 17, 2007
Newsday,The cancer doctor moved to Stony Brook and began studying a combination of cisplatin and etoposide - an intracarotid chemo cocktail.

High-Dose Sequential Chemotherapy with Rituxan® is Superior to ...  -  Jan 11, 2007
Cancer Consultants (press release),...(2) etoposide cyclophosphamide and Rituxan followed by stem cell harvest and (3) high-dose chemotherapy with mitoxantrone and Alkeran® (melphalan) with

Kepivance® May Decrease Oral Mucositis Following High-dose ...  -  Jan 10, 2007
Cancer Consultants (press release),...of the American society of Hematology explored risk factors for OM in patients treated with BEAM (carmustine, etoposide, cytarabine, and melphalan).

Kepivance® May Decrease Oral Mucositis Following High-Dose ...  -  Jan 8, 2007
Cancer Consultants (press release),Alkeran® (melphalan) (200 mg/m2) or high-dose BEAM (carmustine, etoposide, cytarabine and melphalan) followed by autologous stem cell infusion.

Dabur Pharma eyes US, Europe  -  Jan 7, 2007
Business Standard,R & D, Dabur Research Foundation said. The company has already announced its plans for nanotechnology based delivery systems for docetaxel and etoposide.

Researchers Find That a Silent Gene Mutation can Change the ...  -  Dec 27, 2006
GenomicsProteomics.com (press release),P-gp prevents the accumulation of powerful anticancer drugs, such as etoposide and Taxol, in tumor cells. The same pump is also involved in determining how

Gastrointestinal Medications  -  Jan 5, 2007
Psychosomatics (subscription)Watanabe Y, Nakai H, Hoshiai H: The effect of granisetron on in-vitro metabolism of doxorubicin, irinotecan, and etoposide. Curr Med Res Opin 2005;

Zevalin® Can Safely Be Given With High Dose BEAM with Autologous ...  -  Dec 18, 2006
Cancer Consultants (press release),Researchers involved in a multicenter trial demonstrated that doses of Zevalin could be escalated in conjunction with BEAM ((carmustine, etoposide,

Gemtuzumab Induction Therapy Improved Progression Free Survival ...  -  Dec 14, 2006
DG NewsThe regimens were consolidated with amsacrine and etoposide or with high dose cytarabine. Dr. Burnett said the 85% rate of remissions was the same with or

A 'Silent' Gene Mutation Can Change the Function of an Anticancer ...  -  Dec 22, 2006
eMaxHealth.com,P-gp prevents the accumulation of powerful anticancer drugs, such as etoposide and Taxol, in tumor cells. The same pump is also involved in determining how

Concurrent Chemotherapy, Twice-Daily Radiation and Consolidation ...  -  Nov 27, 2006
Cancer Consultants (press release),Researchers from Japan have reported that concurrent twice-daily radiotherapy and standard VePesid® (etoposide) plus Platinol® (cisplatin) followed by

In her own defense  -  Dec 16, 2006
St. Petersburg Times,...are cisplatin and etoposide, but there is clinical trial data that suggest significant survival benefit for irinotecan being included in the chemo mix."

Addition of Zevalin to Transplant Chemotherapy Improves Survival ...  -  Dec 13, 2006
DG NewsZevalin along with a conditioning regimen comprising carmustine, cytarabine, etoposide and melphalan (known as BEAM), said presenter Amrita Krishnan,

ASH: Mylotarg Boosts AML Disease-Free Survival  -  Dec 12, 2006
MedPage Today,...the same two drugs plus etoposide, or FLAG-IDA, a combination fludarabine, Ara-C, granulocyte colony stimulating factor and idarubicin.

ASH: Chemotherapy Regimen Induces Complete Remissions in Burkitt's  -  Dec 11, 2006
MedPage Today,The regimen consists of dose-adjusted Vepesid (etoposide), prednisone, Oncovin (vincristine), Cytoxan (cyclophosphamide), Adriamycin (doxorubicin),

131 Abstracts Evaluating Celgene Products to Be Presented at the ...  -  Dec 7, 2006
PR Newswire (press release),Thal & Metronomic Oral Chemotherapy with Prednisone, Etoposide, Procarbazine and Cyclophosph) in R/R Disease; Abstract 2751 Myelodysplastic Syndromes

Fractionated Camptosar® Plus Paraplatin® Well Tolerated in ...  -  Dec 1, 2006
Cancer Consultants (press release),A combination of VePesid® (etoposide) and Platinol® is the standard treatment option for patients with ED-SCLC. However, due to poor long-term outcomes in

No Added Benefit of Taxol® Following Chemotherapy/Radiation in ...  -  Nov 29, 2006
Cancer Consultants (press release),...therapy with Taxol following treatment with Paraplatin® (carboplatin) and etoposide (VePesid®) plus radiation therapy in patients with Stage III NSCLC.

Pharmion Acquires Cabrellis Pharmaceuticals  -  Dec 4, 2006
Pharmaceutical Online (press release),Earlier studies in first line SCLC combining etoposide and cisplatin (EP), the standard of care in the US, reported an overall response rate of 68 percent.

Lilly Launches Phase III 'GALES' Trial of ALIMTA(R) (Pemetrexed ...  Oct 24, 2006
...combination with carboplatin, a commonly-used chemotherapeutic agent, in direct comparison to the current leading treatment option of etoposide in combination ... -Drug Newswire (press release), Alimta® Safe and Active in Small Cell Lung Cancer  Oct 27, 2006
A phase III trial has recently been initiated to compare adding Alimta to carboplatin versus the standard regimen of etoposide and carboplatin for the ... -Cancer Consultants (press release), Foro de Shell Security - Seguridad informática  Oct 26, 2006
...randomized trial of 4 regimens triac ie, [1] CHOP versus [2] prednisone, methotrexate, leucovorin, d triad xorubicin, cyclophosphamide, and etoposide [Pr trial ... -Shell Security, EntreMed: testing Panzem potential in ovarian cancer  Nov 2, 2006
...to confer anticancer activity in cell lines that are resistant to certain cytotoxic chemotherapy agents, including the taxanes, etoposide, doxorubicin and ... -Pharmaceutical Business Review Index of Online Supplemental Material for  Oct 9, 2006
DNA DSBs. • Figure S2 Modeling of PML NB number and characterization of DSB-induction after etoposide treatment. • Figure S3 ... -Journal of Cell Biology (subscription) Researchers' data from Germany, Japan and Canada advance lung ...  Oct 26, 2006
Irinotecan/cisplatin have been shown to be superior to a standard treatment with etoposide/cisplatin in extensive disease SCLC," scientists writing in the ... -Therapeutics Daily (subscription) (press release), Lilly Begins Alimta Lung Cancer Study  Oct 20, 2006
...with extensive-stage SCLC and give one group Alimta combined with the chemotherapy carboplatin and the other group the chemotherapies etoposide and carboplatin ... -Houston Chronicle, Eli Lilly Reveals Launch Of GALES Trial Of ALIMTA In Extensive ...  Oct 20, 2006
...in combination with carboplatin, a commonly-used chemotherapeutic agent, in direct comparison to the current treatment option of etoposide in combination with ... -Trading Markets, Taxotere® Consolidation May Improve Outcomes for Stage IIIB NSCLC  Oct 24, 2006
Oncology Group (SWOG) have reported that the Taxotere® (docetaxel) consolidation following concurrent Platinol® (cisplatin/VePesid® (etoposide) and thoracic ... -Cancer Consultants (press release), Continued Treatment with Taxotere® May Improve Outcomes for Stage ...  Oct 19, 2006
...in Clinical Lung Cancer, the addition of Taxotere® (docetaxel) following initial treatment with Platinol® (cisplatin) and VePesid® (etoposide) may improve ... -Cancer Consultants (press release), Alimta® Safe and Active in Small Cell Lung Cancer  Oct 24, 2006
Standard treatment for patients with extensive SCLC include VePesid® (etoposide) plus Platinol, VePesid plus Paraplatin or Camptosar® (irinotecan) plus ... -Cancer Consultants (press release), Alimta® Safe and Active in Small Cell Lung Cancer  Oct 23, 2006
The chemotherapy regimen considered the standard of care for extensive-stage SCLC is the combination of the drugs etoposide and cisplatin. ... -Cancer Consultants (press release), Shikonin Derivative Has Potent Anti-Tumor Activity in Vivo and in ...  Sep 15, 2006
Subsequent IV treatment with SH-7 inhibited xenograft growth at concentrations of 2 to 10 mg/kg, proving to be stronger than etoposide and vincristine. ... -Cancerpage.com

Genzyme Begins Phase 3 Pivotal Study of Clolar(R) in Adult Acute ...  Sep 6, 2006
The first phase 1/2 trial is evaluating Clolar in combination with the chemotherapy agents etoposide and cyclophosphamide in patients with no more than two (AML ... -Yahoo! News

Completing Chemo Vital for Patients with Small-Cell Lung Cancer  Aug 29, 2006
...day. This treatment was alternated with etoposide and cisplatin administered on days 1 to 3 in cycles two, four and six. Radiation ... -Cancerpage.com

High-Dose Therapy Confirmed as Effective for Refractory Ewing’s ...  Aug 28, 2006
High-dose regimens involved busulfan and melphalan or etoposide or cyclophosphamide in 30 patients and a total body irradiation regimen in 3. They reported ... -Cancer Consultants

Findings from Denmark, the United States and Israel describe new ...  Aug 28, 2006
All patients were primarily treated with surgery, followed by chemotherapy (carmustine, cisplatine and etoposide) and radiotherapy.". ... -Therapeutics Daily (subscription)

ASH: Mylotarg Boosts AML Disease-Free Survival  -  12 Dec 2006
MedPage Today,...the same two drugs plus etoposide, or FLAG-IDA, a combination fludarabine, Ara-C, granulocyte colony stimulating factor and idarubicin.

131 Abstracts Evaluating Celgene Products to Be Presented at the ...  -  12 Dec 2006
PR Newswire (press release),Thal & Metronomic Oral Chemotherapy with Prednisone, Etoposide, Procarbazine and Cyclophosph) in R/R Disease; Abstract 2751 Myelodysplastic Syndromes

Pharmion Acquires Cabrellis Pharmaceuticals, Gains Rights to ...  -  12 Dec 2006
Earthtimes.orgEarlier studies in first line SCLC combining etoposide and cisplatin (EP),the standard of care in the US, reported an overall response rate of 68percent(6).

Fractionated Camptosar® Plus Paraplatin® Well Tolerated in ...  -  12 Dec 2006
Cancer Consultants (press release),A combination of VePesid® (etoposide) and Platinol® is the standard treatment option for patients with ED-SCLC. However, due to poor long-term outcomes in

No Added Benefit of Taxol® Following Chemotherapy/Radiation in ...  -  12 Dec 2006
Cancer Consultants (press release),...therapy with Taxol following treatment with Paraplatin® (carboplatin) and etoposide (VePesid®) plus radiation therapy in patients with Stage III NSCLC.

ASH: Chemotherapy Regimen Induces Complete Remissions in Burkitt's  -  Dec 11, 2006
MedPage Today,The regimen consists of dose-adjusted Vepesid (etoposide), prednisone, Oncovin (vincristine), Cytoxan (cyclophosphamide), Adriamycin (doxorubicin),

Concurrent Chemotherapy, Twice-Daily Radiation and Consolidation ...  -  Nov 27, 2006
Cancer Consultants (press release),Researchers from Japan have reported that concurrent twice-daily radiotherapy and standard VePesid® (etoposide) plus Platinol® (cisplatin) followed by

Chemotherapy and Twice-daily Radiation Therapy Promising for Small ...  -  Nov 21, 2006
Cancer Consultants (press release),Phase II Study of Etoposide and Cisplatin With Concurrent Twice-Daily Thoracic Radiotherapy Followed by Irinotecan and Cisplatin in Patients With

Completing Chemo Vital for Patients with Small-Cell Lung Cancer  29 Aug 2006
...day. This treatment was alternated with etoposide and cisplatin administered on days 1 to 3 in cycles two, four and six. Radiation ... -Cancerpage.com

High-Dose Therapy Confirmed as Effective for Refractory Ewing’s ...  Aug 28, 2006
High-dose regimens involved busulfan and melphalan or etoposide or cyclophosphamide in 30 patients and a total body irradiation regimen in 3. They reported ... -Cancer Consultants

Findings from Denmark, the United States and Israel describe new ...  Aug 28, 2006
All patients were primarily treated with surgery, followed by chemotherapy (carmustine, cisplatine and etoposide) and radiotherapy.". ... -Therapeutics Daily (subscription)

NO at forefront of medical research  Aug 18, 2006
...cancers. It is widely used in combination chemotherapy with other anti-cancer drugs such as doxorubicin, etoposide, and bleomycin. ... -Irish Medical Times

Addition of Rituxan® to CHOP Safe and Effective for AIDS-Related ...  Aug 18, 2006
There is emerging evidence that Rituxan added to CHOP or CHOP plus etoposide represents the optimal induction therapy for newly diagnosed patients with B-cell ... -Cancer Consultants

Non-Small-Cell Lung Cancer: Advances in the Treatment of Early and ...  Aug 2, 2006
...the CALGB study is the only trial of adjuvant chemotherapy that uses carboplatin instead of cisplatin and uses a taxane instead of a vinca alkaloid or etoposide ... -Medscape (subscription)

Patients 80 Years or Older With NHL Benefit from Chemotherapy  Aug 15, 2006
...therapy. Among the 79 patients treated with chemotherapy 15 received single agent chlorambucil and 2 received oral etoposide. Combination ... -Cancer Consultants

Tandem Autologous Transplants Effective for High-Risk ...  Aug 21, 2006
The myeloablative regimen consisted of Alkeran, Vepesid® (etoposide) and Paraplatin® (carboplatin).The 3-year EFS was 53% for the high-dose group and 30% for ... -Cancer Consultants

Anti-Hu Paraneoplastic Syndrome  Aug 2, 2006
The patient received three cycles of adjuvant chemotherapy (carboplatin and etoposide), and she has subsequently shown a steady improvement, with weight gain ... -New England Journal of Medicine (subscription)

Researchers' work from the United Kingdom, United States and Japan ...  Aug 10, 2006
Japan. Study 1: Heat shock protein 90 inhibitors enhance the activity of topoisomerase II poisons etoposide and mitoxantrone. According ... -Therapeutics Daily (subscription)

Paraplatin®, Camptosar® Supported by Neupogen® Well Tolerated ...  Aug 4, 2006
Lung Cancer . A combination of VePesid® (etoposide) and Platinol® is the standard treatment option for patients with SCLC. However ... -Cancer Consultants

Etoposide Nanocarriers Suppress Glioma Cell Growth by ...  Jun 26, 2006
...advantage of this property, the investigators used their PEG-HS-coated lipid nanocapsule to create a sustained-release formulation of etoposide, a proven ... -AZoNano.com

Minimizing Drug Toxicity  Jul 3, 2006
They found that certain toxic compounds, such as acetaminophen and the anticancer agents staurosporine and etoposide, or their reactive metabolites, actually ... -Chemical & Engineering News

Researchers find molecular "brake"' to cell death  Jul 4, 2006
...release of CC and maximize the decrease of nucleotide levels." Some chemotherapy drugs, like paclitaxel, cisplatin and etoposide, appear, coincidentally and ... -Yemen Observer

Marqibo™ Not Approved for NHL  Jun 30, 2006
...relapsed NHL in combination with the approved cancer drug Rituxan® (rituximab), and relapsed NHL in combination with the approved cancer drug etoposide. ... -Cancer Consultants

Researchers Find Molecular "brake"' To Cell Death  Jul 1, 2006
Some chemotherapy drugs, like paclitaxel, cisplatin and etoposide, appear, coincidentally and perhaps inadvertently, to do both, and are very effective for ... -Medical News Today

Iressa® Study Closed  Jun 30, 2006
Iressa as a therapy for patients with inoperable stage III non-small cell lung cancer who had responded to a regimen of cisplatin, and etoposide with radiation ... -Cancer Consultants

Addition of Thalomid® to Chemotherapy Improves Survival in Small ...  Jun 30, 2006
Although not specified in the abstract the chemotherapy regimen in this study probably included cisplatin, cyclophosphamide and etoposide and possibly ... -Cancer Consultants

Findings from the People's Republic of China, Japan and Canada in ...  Jun 22, 2006
...of China has reported that the transfection of second mitochondria-derived activator of caspase (Smac) sensitizes tumor cells to etoposide-induced apoptosis ... -Therapeutics Daily (subscription)



Hycamtin® More Convenient than Etoposide in Small Cell Lung ...  May 5, 2006
...agent cisplatin (Platinol®) produce nearly equivalent outcomes with increased convenience compared to the intravenous form of etoposide (VePesid®) plus ... - Cancer Consultants

Camptosar®/Carboplatin Improves Progression-Free Survival over ...  Apr 21, 2006
...of Camptosar® (irinotecan) plus Paraplatin® (carboplatin) appears to improve progression-free survival compared with VePesid® (etoposide) plus carboplatin ... - Cancer Consultants

Inhibiting cell process may give cancer drug a boost  May 3, 2006
In addition, treatment with ML-7 in combination with etoposide, a chemotherapy drug used to treat solid tumors, enhanced the ability of etoposide to kill ... - News-Medical.net

Rituxan® Improves Outcomes of Young Patients with Good-Prognosis ...  May 1, 2006
Four chemotherapy regimens were included: CHOP-21, CHOEP-21 (added etoposide), MACOP-B (cyclophosphamide, doxorubicin, methotrexate, oncovin, bleomycin, and ... - Cancer Consultants

Lung cancer CPT-11/SN-38 resistance marked by ABCG2 expression  Apr 20, 2006
..."Because H23/SN-38 cells show cross resistance to certain anticancer drugs, such as topotecan, etoposide, doxorubicin and mitoxantrone, ... - Therapeutics Daily (subscription)

Survival Improving for Patients with Stage IV Follicular Lymphoma  Apr 17, 2006
The third protocol evaluated alternating non-cross resistant regimes with the addition of etoposide, cytarabine, cisplatin and mitoxantrone, the fourth added ... - Cancer Consultants

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