Recent news on Factor Viii

'Used as HIV guinea pigs but no-one even told us we had been infected'  -  25 May 2007
Scotsman,The patients had been given a batch of infected Factor VIII blood product. He had continually asked if there were any risks from Factor VIII but was told

AIDS-Infected Drug was allegedly sold for commercial profit  -  May 18, 2007
Canadian National Newspaper,Unearthed documents show that greed driven interests sold millions of dollars worth of an injectable blood-clotting medicine -- Factor VIII concentrate,

His bruises take months to heal  -  May 1, 2007
Electric New Paper,Kheng Chew has severe factor VIII haemophilia, a mutation in the factor VIII gene. His brother, 5, and his parents are all normal.

Bayer HealthCare Launches Living With Hemophilia Program To ...  -  Apr 26, 2007
Emediawire (press release),Hemophilia A, also known as factor VIII deficiency or classic hemophilia, is largely an inherited bleeding disorder in which one of the proteins needed to

Not all E. coli is bad E. coli  -  May 13, 2007
Milwaukee Journal Sentinel (subscription),This leads to such drugs such as insulin, growth hormones and factor VIII for hemophiliacs. It is often said that clothes make the man.

ThromboGenics Announces Progress With its Pre-Clinical and ...  -  May 2, 2007
PR Newswire (press release),Regarding its clinical portfolio, ThromboGenics announces that all previously announced clinical trials with microplasmin and TB-402 (anti-Factor VIII) are

Talecris Provides Educational Grant to Support World Federation of ...  -  May 3, 2007
CNW Telbec (Communiqués de presse),...the treatment of classical hemophilia (hemophilia A) in which there is a demonstrated deficiency of activity of the plasma clotting factor, factor VIII.

Pall continues patent tussle with Entegris  -  May 8, 2007
LabTechnologist.com,...active ingredients, which is very important when filtrates such as recombinant Factor VIII carry a price of several hundred thousand dollars per gram.

Belgian biotech company raises €23.9M for vascular disease  -  May 10, 2007
Science Business (subscription),ThromboGenics also has one program, TB-402 (Anti-Factor VIII), in Phase I clinical trials, and three other drug candidates in preclinical development with

ThromboGenics Successfully Completes Private Share Offering ...  -  May 9, 2007
Earthtimes.orgThromboGenics also has oneprogram, TB-402 (Anti-Factor VIII), in Phase I clinical trials, and threeother drug candidates in preclinical development with

Bayer HealthCare Launches Living With Hemophilia Program To ...  -  26 Apr 2007
PR Web (press release),Hemophilia A, also known as factor VIII deficiency or classic hemophilia, is largely an inherited bleeding disorder in which one of the proteins needed to

Overexpression of Carcinoma and Embryonic Cytotrophoblast Cell ...  -  Apr 24, 2007
Am J Pathology (subscription)Mig-7 protein primarily co-localized with vasculogenic mimicry markers factor VIII-associated antigen, vascular endothelial-cadherin, and laminin 5 2 chain

Inquiry opens into NHS blood ‘disaster’  -  Apr 18, 2007
The Herald,Nearly 2000 patients who were exposed to HIV and/or hepatitis C from clotting agents such as Factor VIII have since died and many others are said to be

Daily pill to beat genetic diseases  -  Apr 23, 2007
The Sunday Times,In haemophilia, it is the gene for the clotting agents factor VIII or factor IX that is disrupted. PTC124 works by binding to a part of the cell called the

British tainted blood inquiry begins  -  Apr 18, 2007
CBC - Newfoundland & Labrador,Hemophilia is a genetically inherited condition in which an essential blood clotting factor, factor VIII, is missing from the patient's blood.

Widow accuses doctors over donor blood risks  -  Apr 18, 2007
Guardian Unlimited,A total of 4676 people were infected with hepatitis C and of these 1200 also contracted HIV via a plasma product called Factor VIII made from blood taken

Contaminated blood inquiry starts in controversy  -  Apr 18, 2007
Medical Laboratory World,Nonetheless, factor VIII imports from the US continued to be used, and even when safer heat-treated versions came along, it was left to local physicians to

Haemophiliac deaths 'avoidable'  -  Apr 18, 2007
BBC News,Currently, the condition can only be treated by injections of the clotting chemical, known as Factor VIII. In the early 1970s, patients were treated with

Bayer HealthCare Pharmaceuticals Provides euro 250.000 Grant to ...  -  Apr 16, 2007
PR Newswire (press release),Donating more than 30 million units of factor VIII to developing countries that cannot provide adequate medical care to people with hemophilia.

Wyeth Receives FDA Approval for New BeneFIX Features That Provide ...  -  Mar 29, 2007
Drug Newswire (press release),People with hemophilia are deficient in one of the key proteins -- either factor VIII (hemophilia A) or factor IX (hemophilia B) -- that are vital in the

Bayer HealthCare Pharmaceuticals Provides euro 250.000 Grant to ...  -  Apr 16, 2007
PR Newswire (press release),Bayer demonstrates its commitment in many ways, including: * Donating more than 30 million units of factor VIII to developing countries that cannot provide

Report says Britain knew of blood risks  -  Apr 18, 2007
Science Daily (press release)Analysis: FDA eyes factor VIII products (December 14, 2006) -- The Food and Drug Administration is set to examine Friday whether plasma-derived factor VIII

Blood clotting protein extracted from pig milk  -  Apr 12, 2007
China Post,Besides factor IX, there are several other clotting proteins responsible for different types of hemophilia, such as factor VIII for type A and factor XI for

GE and BAC extend purification pact  -  Apr 2, 2007
In-PharmaTechnologist.com,...(BAC) have extended their biopharmaceutical partnership to develop purification media for Factor VIII (FVIII) for the treatment of haemophilia A.

ZLB Behring Announces Availability of Humate-P(R) with Smaller Diluent  -  Apr 12, 2007
Drug Newswire (press release),In addition, Humate-P contains the quantity of von Willebrand factor and factor VIII that is important for treating VWD. Von Willebrand disease, the most

Every Click Counts For Sport - Haemophilia  -  Apr 18, 2007
Medical News Today (press release),However, it is a lifelong condition needing regular treatments of factor VIII to aid the clotting process and stop blood leaking into joints.

[FULL STORY]  -  Apr 20, 2007
Advertiser,People with severe hemophilia are usually on prophylaxis treatments (infusing regular doses of factor VIII, the clotting agent) two or three times a week,

Haemophilia fight for tot  -  Mar 29, 2007
Melbourne Herald Sun,The couple learned Nathan's haemophilia could be controlled with a blood thickening medication called Factor VIII. Thrice weekly injections, topped with

IndyCar Racer Marco Andretti Drives Support for Hemophilia ...  -  Apr 6, 2007
PR Web (press release),The disease is caused by deficient or defective blood coagulation proteins, known as factor VIII or IX. The most common form of the disease is hemophilia A,

Letters: Blood inquiry would be in my interest  -  Apr 20, 2007
Guardian Unlimited,...in the early 1980s, closed the only British laboratory supplying the NHS with blood products such as factor VIII,"saving" a few thousand pounds a year.

Iona freshman, a hemophiliac, died of bleeding in brain  -  Apr 12, 2007
White Plains Journal News,Lynch had a severe form of Hemophilia A, a hereditary bleeding disorder caused by a lack of the blood clotting factor VIII, and was taking the medication

Thrombogenics Announces License Agreement With Millipore for ...  -  Apr 16, 2007
PR Newswire (press release),ThromboGenics also has one program, TB-402 (Anti-Factor VIII), in Phase I clinical trials, and four other drug candidates, including TB-403 (Anti-PlGF),

Bayer Healthcare Pharmaceuticals launches in the US  -  Apr 5, 2007
News-Medical.net,...imaging -- A recombinant human factor VIII treatment recommended for people living with hemophilia A -- A unique intrauterine contraceptive system,

Electromechanical characterization of a tissue-engineered ...  -  Mar 29, 2007
The Journal of Thoracic and Cardiovascular SurgeryResults: Histologic examinations showed repopulation of the scaffold with cells, including a monolayer of factor VIII–positive cells in the endocardial

GO Capital Becomes Major Shareholder in ThromboGenics  -  Mar 27, 2007
PR Newswire (press release),...drug candidates in preclinical development with preclinical proof-of-principle demonstrated, including TB-402 (Anti-Factor VIII) and TB-403 (Anti-PlGF).

Wyeth Receives FDA Approval for New BeneFIX Features That Provide ...  -  27 Mar 2007
PipelineReview.com (press release),People with hemophilia are deficient in one of the key proteins -- either factor VIII (hemophilia A) or factor IX (hemophilia B) -- that are vital in the

GO Capital Becomes Major Shareholder in ThromboGenics  -  27 Mar 2007
PR Newswire (press release),...drug candidates in preclinical development with preclinical proof-of-principle demonstrated, including TB-402 (Anti-Factor VIII) and TB-403 (Anti-PlGF).

Pain Therapeutics Licenses Biotechnology To Treat Rare Disorder  -  Mar 22, 2007
PR Newswire (press release),People with hemophilia are deficient in the key proteins-Factor VIII (hemophilia A) or Factor IX (hemophilia B)- that are vital to prevent uncontrolled

CSL Behring's Helixate(R) FS and Mix2Vial(TM) Now Packaged ...  -  Feb 25, 2007
Drug Newswire (press release),Helixate(R) FS is a recombinant factor VIII treatment for hemophilia A that offers a more convenient administration by utilizing a 2.5-mL volume diluent,

Bayer HealthCare Awards Grant to National Hemophilia Foundation's ...  -  Feb 27, 2007
PR Newswire (press release),Hemophilia A, also known as factor VIII deficiency or classic hemophilia, is largely an inherited bleeding disorder in which one of the proteins needed to

Cell culture must go vegetarian  -  Mar 7, 2007
Pharmaceutical Technology Europe,In the UK, over 1000 people with haemophilia were infected with HIV through blood-derived Factor VIII (FVIII) treatment. Recombinant FVIII, produced by

No go for Novo's potential stroke therapy  -  Feb 28, 2007
DrugResearcher.com,ReFacto is based on Factor VIII and BeneFix on Factor IX. In a separate announcement, Novo recently said it will provide a "significant unrestricted grant

Bayer HealthCare Awards Grant to National Hemophilia Foundation's ...  -  Feb 27, 2007
PR Newswire (press release),About Hemophilia A Hemophilia A, also known as factor VIII deficiency or classic hemophilia, is largely an inherited bleeding disorder in which one of the

Testing new waters  -  Mar 5, 2007
Financial Express,Other products include growth hormones, Granulocyte Stimulating Factor, Follicle Stimulating Factor, Blood Factor VIII, Tissue Plasmogen Activator and

Inhaled Celecoxib shows new promise for lung cancer treatment  -  Mar 6, 2007
News-Medical.net,...anti-tumor effect mediated via reduced prostaglandin E 2 (PGE 2 ) , IL-8 and Factor VIII levels and increased apoptosis mediated via Fas pathway.

CSL Behring's Helixate(R) FS and Mix2Vial(TM) Now Packaged ...  -  Feb 20, 2007
Earthtimes.orgHelixate(R) FS is a recombinant factor VIII treatment for hemophilia A that offers a more convenient administration by utilizing a 2.5-mL volume diluent,

CSL Behring's Helixate(R) FS and Mix2Vial(TM) Now Packaged ...  -  Feb 20, 2007
PR Newswire (press release),About Helixate(R) FS Helixate(R) FS is a recombinant factor VIII treatment for hemophilia A that offers a more convenient administration by utilizing a

The market of recombinant coagulation factors is growing with next ...  -  Feb 17, 2007
PR Leap (press release),Development of next generation Factor VIII products is based on prolonging the half-life of the existing proteins by drug delivery technologies.

Thrombogenics and Bioinvent trial anticoagulant  -  Feb 14, 2007
DrugResearcher.com,Blood clots are formed by a mechanism known as the coagulation cascade, which involves numerous proteins, including Factor VIII. Sometimes the cascade can

ThromboGenics and BioInvent Receive Approval to Begin Clinical ...  -  Feb 11, 2007
netPR.pl (komunikaty prasowe),TB-402 is a human antibody binding to Factor VIII, which plays a crucial role in the coagulation of the blood. The project is being developed within the

EU-Approval For Continuous Infusion Of KOGENATE® Bayer  -  Feb 12, 2007
Medical News Today (press release),KOGENATE® Bayer, a recombinant Factor VIII product for the treatment of hemophilia A, received EU approval for continuous infusion in hemophilia A patients

Bayer HealthCare and CSL Behring Extend Agreement for Supply of ...  -  Feb 2, 2007
PharmaLive.com (press release),1, 2007— Bayer HealthCare announced today the extension of an agreement with CSL Behring to distribute Bayer’s Recombinant Factor VIII Kogenate® under the

Bayer HealthCare and CSL Behring extend agreement for supply of ...  -  Feb 1, 2007
Prdomain Business Register (press release),1 Feb 2007 , Leverkusen : Bayer HealthCare announced today the extension of an agreement with CSL Behring to distribute Bayer’s Recombinant Factor VIII

EU-Approval for Continuous Infusion of KOGENATE(R) Bayer  -  Feb 9, 2007
PipelineReview.com (press release),...„In contrast to bolus infusion, continuous infusion of Factor VIII can lower the risk that factor levels will drop below the therapeutic hemostatic level,

Grifols announces FDA approval of Alphanate  -  Feb 2, 2007
Antara (press release),For other types of bleeding, infusions of a factor VIII concentrate rich in von Willebrand factor, such as Alphanate(R) may be required.

Grifols Announces FDA Approval of Alphanate(R) to Treat von ...  -  Feb 1, 2007
Yahoo! News (press release)For other types of bleeding, infusions of a factor VIII concentrate rich in von Willebrand factor, such as Alphanate® may be required.

FDA Approves New Product to Treat Von Willebrand Disease  -  Feb 9, 2007
eMaxHealth.com,Alphanate is already approved for the prevention and control of bleeding in patients with Factor VIII deficiency due to hemophilia A or acquired Factor VIII

ThromboGenics and BioInvent Receive Approval to Begin Clinical ...  -  Feb 11, 2007
Earthtimes.orgWe are bothexcited about the potential of this novel anti-coagulant, which acts viabinding to Factor VIII, to prevent thrombosis in a number important

Baxter's Advate Receives Room Temperature Storage Approval  -  Feb 12, 2007
Medical News Today (press release),Baxter Healthcare Ltd. today announced the approval of room temperature storage for Advate, the only factor VIII product processed without blood-based

CSL Behring and Bayer Extend Agreement for Supply of Helixate ...  -  Feb 2, 2007
PharmaLive.com (press release),Under the contract extension, Bayer will continue to supply Helixate (R) recombinant coagulation Factor VIII to CSL Behring through 2017.

CSL Behring and Bayer Extend Agreement for Supply of Helixate(R ...  -  Feb 1, 2007
PR Newswire (press release),At the same time, the companies settled outstanding litigation relating to the supply of recombinant Factor VIII. Terms of the settlement were not disclosed

Green light for Bioinvent trial  -  Feb 13, 2007
Säkerhet & Sekretess,TB-402 is a human antibody binding to Factor VIII, which plays a crucial role in the coagulation of the blood. Extensive testing in several animal models

FDA Okays Alphanate for von Willebrand's Patients in Surgery  -  Feb 2, 2007
MedPage Today,Alphanate was previously approved for the prevention and control of bleeding in patients with factor VIII deficiency due to hemophilia A or acquired factor

Wyeth Pharmaceuticals and Nautilus Biotech Announce Collaboration ...  -  Feb 5, 2007
Earthtimes.orgPeople with hemophilia are deficient in one of the key proteins - either Factor VIII (hemophilia A) or Factor IX (hemophilia B) - that are vital in the

Wyeth Pharmaceuticals and Nautilus Biotech Announce Collaboration ...  -  Feb 5, 2007
CNW Telbec (Communiqués de presse),People with hemophilia are deficient in one of the key proteins -- either Factor VIII (hemophilia A) or Factor IX (hemophilia B) -- that are vital in the

FDA Approves Marketing Biologic Alphanate for von Willebrand Disease.  -  Feb 2, 2007
Biologic Drug Report,Alphanate has been used for a decade to prevent and control of bleeding in patients with Factor VIII deficiency due to hemophilia A or acquired Factor VIII

CSL Behring and Bayer Extend Agreement Related to Hemophilia  -  Feb 2, 2007
Genetic Engineering News (press release),...property related to recombinant FVIII. At the same time, the companies settled outstanding litigation relating to the supply of recombinant Factor VIII.

CSL Secures Long Term Supply of Helixate from Bayer  -  Feb 2, 2007
PharmaLive.com (press release),...that had facilitated an extension of the arrangements with Bayer for the supply of Helixate FS, CSL Behring’s recombinant Factor VIII product.

Wyeth pens three deals in a day  -  Feb 6, 2007
In-PharmaTechnologist.com,Haemophilia is a rare blood-clotting disorder, affecting around 130000 people worldwide, and is caused by a deficiency in one of two proteins - Factor VIII

Wyeth Pharmaceuticals, France's Nautilus Biotech in hemophilia B ...  -  Feb 5, 2007
ABCmoney.co.uk,Patients with the blood-clotting disorder hemophilia A or hemophilia B are dependent on protein replacement therapy with Factor VIII or Factor IX

Grifols Announces FDA Approval of Alphanate(R) to Treat von ...  -  Feb 1, 2007
Earthtimes.orgAntihemophilic factor potency (Factor VIII:C activity) isexpressed in International Units (IU) on the product label. Additionally,each vial of Alphanate(R)

APS: Grifols Announces FDA Approval of Alphanate(R) to Treat .....  -  Feb 1, 2007
ANP Pers Support,There are several treatment options depending on whether the VWD is mild or. boost Factor VIII and von Willebrand levels. For other types of bleeding,

Biogen Idec acquires Brandeis spin-out  -  Jan 31, 2007
EurekAlert (press release),Syntonix is pursuing other early-stage programs, including a long-acting factor VIII program, with the potential to improve the treatment of hemophilia A.

CSL Ltd.: Interim Result - Strong Profit from Operations, Up 46 ...  -  Feb 21, 2007
PharmaLive.com (press release),...agreement with Sanofi-Aventis that facilitated an extension of arrangements with Bayer for the supply of Helixate®, a recombinant Factor VIII product.

Wyeth Pharmaceuticals and Nautilus Biotech Announce Collaboration ...  -  Feb 5, 2007
Earthtimes.orgPeople with hemophilia are deficientin one of the key proteins - either Factor VIII (hemophilia A) or Factor IX(hemophilia B) - that are vital in the

Wyeth Pharmaceuticals and MediVas Announce Research Partnership to ...  -  Feb 6, 2007
PipelineReview.com (press release),People with hemophilia are deficient in one of the key proteins – either Factor VIII (hemophilia A) or Factor IX (hemophilia B) – that are vital in the

ThromboGenics - Business Update and Half Year Results to End ...  -  Feb 15, 2007
PR Newswire (press release),...its partner BioInvent International received regulatory approval to begin clinical trials with the anticoagulant TB-402 (anti-factor VIII) in Denmark.

Wyeth Pharmaceuticals and MediVas Announce Research Partnership to ...  -  Feb 5, 2007
Earthtimes.orgPeople with hemophilia are deficient in oneof the key proteins - either Factor VIII (hemophilia A) or Factor IX(hemophilia B) - that are vital in the

BioInvent Announces Financial Statement: 1 January - 31 December 2006  -  Feb 15, 2007
PharmaLive.com (press release),TB-402 is a human antibody binding to Factor VIII, which plays a crucial role in the coagulation of the blood. The antibody has shown a beneficial partial

Wyeth Pharmaceuticals and Nautilus Biotech Announce Collaboration ...  -  Feb 4, 2007
Earthtimes.orgPeople with hemophilia are deficientin one of the key proteins -- either Factor VIII (hemophilia A) or Factor IX(hemophilia B) -- that are vital in the

'Bloodbot' Helps Keep Canadian Blood Clean  -  Feb 15, 2007
Science Daily (press release)More than 160 million units of Factor VIII blood product are transfused in Canada each year, said Ritchie, whose lab receives blood samples from 25 clinics

Researcher Part of Study Connecting Diet with Vascular Disease  -  Feb 9, 2007
UVM News,Some of those risk factors include homocysteine, factor VIII, and von Willebrand factor. Diet and family history can contribute to high levels of

Wyeth boosts pipeline with three deals  -  Feb 8, 2007
In-PharmaTechnologist.com,It is a blood-clotting disorder caused by a deficiency in one of two proteins - Factor VIII (haemophilia A) or Factor IX (haemophilia B).

Privately-backed inquiry into contaminated blood  -  Feb 20, 2007
Medical Laboratory World,The patients were infected in the 1970s and 1980s following transfusions of factor VIII, a chemical which is missing in the blood of haemophiliacs and helps

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