Recent news on Fibroblast Growth Factor-

CVBT Banks on Fibroblast Growth Factor  -  May 15, 2007
Genetic Engineering News (press release),The company just completed a Phase I study and is starting a Phase II trial of fibroblast growth factor in coronary heart disease. Angiography reveals that

A relative of anti-aging gene Klotho also influences metabolic ...  -  May 9, 2007
exduco.net,For example, fibroblast growth factor 21, or FGF21, is a hormone in the blood that has been shown to lower blood glucose levels in diabetic and obese mice.

Targeting Sugar On Blood Vessels May Inhibit Cancer Growth  -  May 12, 2007
Medical News Today (press release),An example would be developing small-molecule inhibitors of Ndst1. By affecting a broad array of molecules - such as VEGF, fibroblast growth factor,

Cardiopulmonary Support and Physiology  -  May 2, 2007
The Journal of Thoracic and Cardiovascular SurgeryEnhanced endothelialization of expanded polytetrafluoroethylene grafts by fibroblast growth factor type 1 pretreatment. Surgery 1992;112:244-254discussion

Torrey Pines scientists studying ways to help you live better  -  May 7, 2007
TCPalm,Levin discovered his possible treatment while researching the Fibroblast Growth Factor protein. In one size of the protein, Levin found it did some

Ultra-Pricey Cosmetics  -  Apr 26, 2007
Forbes,Youth Recruit's patented fibroblast growth factor, a molecule that expedites the regeneration of lost cells, promises to make skin 45% smoother after

Epigenetic Silencing through DNA and Histone Methylation of ...  -  Apr 24, 2007
Am J Pathology (subscription)Four members of the fibroblast growth factor receptor (FGFR) family of tyrosine kinases transduce signals of a diverse group of more than 23 fibroblast

A Homeobox Gene Related to Drosophila Distal-Less Promotes Ovarian ...  -  Apr 24, 2007
Am J Pathology (subscription)Moreover, increased levels of these fibroblast growth factor-2 isoforms induced vascular endothelial growth factor expression in tumor cells.

A relative of anti-aging gene Klotho also influences metabolic ...  -  Apr 25, 2007
innovations report,For example, fibroblast growth factor 21, or FGF21, is a hormone in the blood that has been shown to lower blood glucose levels in diabetic and obese mice.

SinoBiomed Wins Approval For External Use Of Growth Factor  -  Apr 16, 2007
Seeking Alpha,OB) announced that its subsidiary Shanghai Wanxing received approval in China for its lyophilized recombinant human acidic fibroblast growth factor for

Gene Therapy, Cancer-Killing Viruses And New Drugs Highlight Novel ...  -  Apr 23, 2007
Medical News Today (press release),One of these proteins, fibroblast growth factor (FGF), was thought to be involved in angiogenesis, but the other, chemokine stroma-cell-derived factor 1

CardioVascular BioTherapeutics to Present at the 4th Annual World ...  -  Apr 16, 2007
PharmaLive.com (press release),CVBT is developing a technology to administer human Acidic Fibroblast Growth Factor, also known as Fibroblast Growth Factor-1 (FGF-1), to stimulate new

ImClone Systems Showcases Extensive Research and Development ...  -  Apr 19, 2007
PharmaLive.com (press release),...platelet-derived growth factor receptor alpha (PDGFR(alpha)), FMS-like tyrosine kinase 3 receptor (FLT3), fibroblast growth factor receptor 3 (FGFR3),

Ultra-Pricey Cosmetics  -  Apr 24, 2007
Forbes,Youth Recruit's patented fibroblast growth factor, a molecule that expedites the regeneration of lost cells, promises to make skin 45% smoother after

Drug Studies: Gene Therapy, Cancer-Killing Viruses and New Drugs  -  Apr 20, 2007
WebWire (press release),One of these proteins, fibroblast growth factor (FGF), was thought to be involved in angiogenesis, but the other, chemokine stroma-cell-derived factor 1

Rebuilding the coronary vasculature: hedgehog as a new candidate ...  -  Apr 10, 2007
HeartZine,Thus far, two potential proangiogenic factors have been intensively examined, fibroblast growth factor and vascular endothelial growth factor.

Recentin Prolongs Survival in Patients With Glioblastoma ...  -  Apr 19, 2007
DG NewsFinally, circulating proteins were also measured and elevations in two of these proteins -- basic fibroblast growth factor (bFGF) and stromal cell derived

Sinobiomed Inc.: rhaFGF Product Received New Drug Certificate  -  Apr 11, 2007
CCNMatthews (press release),...lyophilized recombinant human acidic fibroblast growth factor for external use (rhaFGF), which was awaiting approval from the Chinese State Food and

The emerging role of the FGF23-klotho axis in renal regulation of ...  -  Apr 17, 2007
Journal of EndocrinologyThe importance of the fibroblast growth factor-23 (FGF23)-klotho axis in regulating mineral ion homeostasis has been proposed from recent research

A Mutation in the Fibroblast Growth Factor Receptor 1 Gene Causes ...  -  Mar 6, 2007
Journal of Clinical Endocrinology and Metabolism,Currently, the fibroblast growth factor receptor 1 (FGFR1) gene is the only known autosomal dominant cause of KS, which is also associated with synkinesia,

Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis  -  Mar 8, 2007
AJP - Cell Physiology (subscription)Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells: In vivo neovascularization

Additional Genetic Mutations Found That May Cause Cleft Lip Palate  -  Mar 9, 2007
eMaxHealth.com,The investigation focused on genes in the fibroblast growth factor (FGF) family, which function in a signaling pathway important in fetal face development,

Developmental Biology in Orthopaedics Summary of the 2006 AAOS ...  -  Mar 1, 2007
Journal of Bone and Joint Surgery (subscription)...transforming growth factor- (TGF- ), fibroblast growth factor (FGF), and wingless-type MMTV (mouse mammary tumor virus) integration site family (WNT).

Crossed Polydactyly Prenatally Diagnosed by 2- and 3-Dimensional ...  -  Mar 23, 2007
Journal of Ultrasound in Medicine (subscription)In addition, FGF (fibroblast growth factor), 5'-HoxD (homeobox D), and ALX4 (homeobox protein aristaless-like 4) are also known to be involved in the

Update in Osteoporosis and Metabolic Bone Disorders  -  Mar 6, 2007
Journal of Clinical Endocrinology and Metabolism,...it is now recognized that the matrix protein dentin matrix protein-1 enhances the release of the phosphate-regulating factor fibroblast growth factor 23

More Gene Mutations Drive Cancer Than Previously Thought  -  Mar 8, 2007
Medical News Today,...in the Fibroblast Growth Factor Receptor signalling pathway was hit much more than we expected, particularly in colorectal cancers," said Dr Futreal.

Largest Genome Study Of Cancer Types Finds Many Mutations  -  Mar 10, 2007
Medical News Today (press release),Dr Futreal explains: "For example, we found that a group of kinases involved in the Fibroblast Growth Factor Receptor signalling pathway was hit much more

Genome study drives cancer drug development  -  Mar 9, 2007
DrugResearcher.com,..."We found that a group of kinases involved in the Fibroblast Growth Factor Receptor signalling pathway was hit much more than we expected, particularly in

Greater number of cancer genes discovered  -  Mar 8, 2007
InTheNews.co.uk,Dr Andy Futreal, another co-leader of the project, said: "For example, we found that a group of kinases involved in the fibroblast growth factor receptor

Growth Factor May Interfere With Normal Blood Cell Production  -  Feb 8, 2007
Science Daily (press release)...fibroblast growth factor 2 (FGF-2), in mouse and human cells. They found that FGF-2 inhibits a gene that is critical in regulating hematopoiesis.

Vical Reports 2006 Financial Results  -  Feb 20, 2007
Earthtimes.orgInitiation of a Phase 3 trial by the company's licensee, Sanofi Aventis Group, for the gene-based delivery of Fibroblast Growth Factor 1 (FGF-1),

US Patent Office allows CVBT's patent application for injection of ...  -  Feb 1, 2007
Therapeutics Daily (subscription) (press release),This patent describes the technology to produce human acidic fibroblast growth factor, also known as fibroblast growth factor-1 (FGF-1), its delivery via

Hyperproduction of Hyaluronan in Neu-Induced Mammary Tumor ...  -  Feb 23, 2007
Am J Pathology (subscription)In Matrigel plug assays, basic fibroblast growth factor-induced neovascularization was elevated in the presence of either hyaluronan oligosaccharides or a

REGENERATIVE MEDICINE ORGANIZATION CONFERENCE SPEAKER AND TOPIC ...  -  Jan 31, 2007
Fast Pitch! (press release)His most noted work has been with nerve growth factor and fibroblast growth factor. Dr. Bradshaw is the founding father of the Protein Society and is on the

SmallCap Sentinel: Patents as a Path to Market  -  Feb 15, 2007
Primenewswire (press release),CVBT is a biopharmaceutical company developing formulations of its active pharmaceutical ingredient (API), Fibroblast Growth Factor-1, to treat a number of

Full Text  -  18 Jan 2007
Science Magazine (subscription)...vascular endothelial growth factor, insulin-like growth factor, fibroblast growth factor 2, and neuropeptide Y), there may be a rapid response of the

US Patent Office Allows CVBT's Patent Application for the ...  -  Jan 9, 2007
Genetic Engineering News (press release),This patent describes the technology to produce human Acidic Fibroblast Growth Factor, also known as Fibroblast Growth Factor-1 (FGF-1), its delivery via

CVBT Obtains Patent for Injection of Angiogenic Protein into the Heart  -  Jan 9, 2007
Genetic Engineering News (press release),CardioVascular BioTherapeutics received approval on its patent describing the technology to produce human acidic fibroblast growth factor, its delivery via

CVBT gets patent on direct-inject heart Rx  -  Jan 9, 2007
United Press InternationalThe company said the newly issued patent covers a method for injecting its Fibroblast Growth Factor-1 -- designed to stimulate new blood-vessel growth,

Multiple repressor pathways contribute to phenotypic switching of ...  -  Jan 11, 2007
AJP - Cell Physiology (subscription)Modulation of smooth muscle proliferation in rat carotid artery by platelet-derived mediators and fibroblast growth factor-2. Platelets 12: 352–358, 2001.

Type of bladder tumor determines treatment  -  Jan 7, 2007
St. Petersburg Times,They describe abnormalities in the FGFR (fibroblast growth factor receptor) gene and constitutive activation of the H-ras oncogene pathways in superficial,

CITED2 is expressed in human adrenocortical cells and regulated by ...  -  Dec 13, 2006
Journal of EndocrinologyAs corticotropin (ACTH) and basic fibroblast growth factor (bFGF) are connected to the physiology and growth of adrenocortical cells we studied the

Cardium Announces Formation of Scientific Advisory Board  -  Nov 30, 2006
Drug Newswire (press release),During the course of this work, he discovered and cloned the gene for human fibroblast growth factor 4 (FGF4), whose angiogenic activity mediates the

Multiple Myeloma Research Foundation (MMRF) Awards $1 Million Each ...  -  Dec 5, 2006
PR Newswire (press release),The association of fibroblast growth factor receptor 3 (FGFR3) expression with t(4;14) multiple myeloma and the demonstration of the transforming potential

Hard Facts for Potential Coronary Bypass Victims  -  Dec 5, 2006
Blogger News NetworkSuch angiogenic proteins include the endothelial growth factor, vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF).

Embryonic patterning makes the feathers fly  -  Dec 10, 2006
Biology News Net (press release),Feathers, or more properly feather buds, will appear on the skin of the developing embryo wherever fibroblast growth factor (FGF) is activated.

A Complex Oscillating Network of Signaling Genes Underlies the ...  -  Dec 7, 2006
Science Magazine (subscription)Mutually exclusive activation of the notch–fibroblast growth factor and Wnt pathways during each cycle suggests that coordinated regulation of these three

Parkinson's Approach With Stem Cells A Promising First Step  -  Dec 5, 2006
Medical News Today (press release),They began by isolating human embryonic stem cells, then using genes such as "sonic hedgehog" and fibroblast growth factor 8 that make chemicals in the

Genetic Ablation of Vitamin D Activation Pathway Reverses ...  -  Dec 5, 2006
Am J Pathology (subscription)Fibroblast growth factor-23 (FGF-23) is one of the circulating phosphaturic factors associated with renal phosphate wasting.

Potential new therapeutic target for breast cancer  -  Dec 5, 2006
Public Health Genetics Unit Newsletter,From within this region, the gene FGFR1 was found to be over-expressed; this gene encodes the fibroblast growth factor receptor one, which is a cellular

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