Recent news on Ganciclovir

New Data Show Oral Valcyte(R) (valganciclovir) as Effective as iv ...  -  May 9, 2007
campus med,These important data show that oral valganciclovir has clinical equivalence to the current gold-standard treatment, intravenous ganciclovir,

New Data Show Oral Valcyte(R) (valganciclovir) as Effective as iv ...  -  May 9, 2007
Juraforum.de,These important data showthat oral valganciclovir has clinical equivalence to the currentgold-standard treatment, intravenous ganciclovir,

Questions and Answers on Recommendation for the Refusal of the ...  -  Apr 27, 2007
PharmaLive.com (press release),Cerepro was to be used in combination with ganciclovir sodium to treat high-grade glioma in patients who are eligible for surgery.

Ark Therapeutics Group Announces EMEA Decision on Cerepro Phase II ...  -  Apr 27, 2007
PharmaLive.com (press release),In the following days, ganciclovir, is given intravenously. Once treated, healthy brain cells surrounding the site where the tumour was removed express the

Ark Therapeutics Grp - Research Update  -  Apr 24, 2007
PipelineReview.com (press release),In the following days, ganciclovir, is given intravenously. Once treated, healthy brain cells surrounding the site where the tumour was removed express the

Sirion Therapeutics Receives Orphan Drug Designation For ...  -  Apr 17, 2007
Medical News Today (press release),..."We are pleased to receive orphan drug designation from the FDA for ganciclovir," said Christine Miller, Sirion's Vice President of Regulatory Affairs.

FDA advances Sirion drug  -  Apr 16, 2007
Tampa Bay Business Journal,The Food and Drug Administration has granted orphan drug designation to ganciclovir, a drug designed to treat a leading cause of blindness.

Sirion granted orphan drug designation for herpetic keratitis ...  -  Apr 16, 2007
OSN SuperSite (subscription),Sirion Therapeutics has received orphan drug designation from the US Food and Drug Administration for Virgan, a ganciclovir-based acute herpetic keratitis

Sirion Therapeutics Completes $45 Million Series B Financing  -  Apr 9, 2007
PR Newswire (press release),ST-605 is a topical ophthalmic gel containing ganciclovir for the treatment of certain viral and superficial eye infections. The product is currently

Sirion Series B Raises $45M For Phase III Ophthalmic Bid  -  Apr 9, 2007
BioWorld Online,The company also has ST-605, a topical gel with ganciclovir for viral and superficial eye infections, already marketed in Europe by Laboratoires Thea,

Advances and Technical Standards in Neurosurgery. Vol. 31  -  Apr 6, 2007
AJNR (subscription),There is a discussion of ongoing clinical trials involving thymidine kinase–ganciclovir therapy and other strategies such as triggering apoptosis in tumor

Mergers, Acquisitions, etc.  -  Feb 16, 2007
OSN SuperSite (subscription),Sirion Therapeutics has obtained exclusive US rights to develop and market a topical ganciclovir gel as a treatment for herpes simplex keratitis and other

Immunoglobulin Prevents Early Non-Hodgkin’s Lymphoma in Transplant ...  -  Feb 8, 2007
Cancer Consultants (press release),Prevention of CMV can be accomplished with antiviral drugs (acyclovir or ganciclovir) or immunoglobulin against CMV (protein that helps fight infection).

Roche Posts Outstanding Results for 2006  -  Feb 7, 2007
PharmaLive.com (press release),Virology - sales growth driven mainly by Tamiflu Combined sales of Valcyte (valganciclovir) and Cymevene (ganciclovir) continued to show strong growth in

Quality by Design (QbD)  -  Feb 12, 2007
Pharmaceutical Processing,Review of Ganciclovir intermediate manufacture 3 suggests that the synthesis can be modified and simplified to produce only the desired isomer only.

Sirion Therapeutics Acquires US License To Develop New Treatment ...  -  18 Jan 2007
Medical News Today (press release),..."Topical ganciclovir has been available in Europe for the treatment of ocular viral infections for over 10 years. This product has the potential to fill a

MedImmune Completes Sale of CytoGam(R)  -  Dec 18, 2006
PR Newswire (press release),...other than kidney from CMV seropositive donors into seronegative recipients, prophylactic CMV-IGIV should be considered in combination with ganciclovir.

ZLB Behring Buys CytoGam Immunoglobulin Therapy Used In Organ ...  09 Nov 2006
...organs other than kidney from CMV seropositive donors into seronegative recipients, prophylactic CMV-IVIg should be considered in combination with ganciclovir. ... -PharmaLive.com (press release), Options for treating ganciclovir-resistant CMV discussed at IDSA ...  Oct 16, 2006
This is of significant concern as CMV can become resistant to the current standard-of-care medications, ganciclovir and valganciclovir, leaving few treatment ... -Aidsmap, European Patent Granted for Cerepro  Oct 13, 2006
In the following days, ganciclovir, is given intravenously. ... This converts the ganciclovir to a substance which specifically kills dividing cells. ... -PharmaLive.com (press release), Recent findings in imaging described by researchers from Taiwan ...  Aug 17, 2006
...research from Taiwan, imaging of lung metastases model and gene therapy can be achieved using herpes simplex virus type 1 Thy kinase (HSV1-tk) and ganciclovir. ... -Therapeutics Daily (subscription)

Laryngeal stenosis associated with chronic graft-versus-host ...  Aug 1, 2006
On day 47, he developed cytomegalovirus-associated interstitial pneumonia and ganciclovir resulted in resolution of the pneumonia. ... -Nature.com (subscription)

LTKfarma Announces its Creation and Names Advisory Board  Jul 6, 2006
...suicide" gene coding for a viral enzyme, the herpes virus thymidine kinase (TK) that is able to transform chemically an inactive drug (ganciclovir) into a ... -CNW Telbec (Communiqués de presse)

LTKfarma announces its creation and names advisory board  Jul 6, 2006
TK is able to transform chemically an inactive drug (ganciclovir, usually used for the treatment of herpes infections) into a derivative that is toxic to ... -PharmaLive.com

New Mouse Model Of Kaposi Sarcoma-associated Herpesvirus Infection  Jun 25, 2006
...these animals. Importantly, viral growth was dramatically inhibited by administration of the antiviral drug ganciclovir. This mouse ... -Medical News Today

Mary Jane Gore  Jul 5, 2006
The researchers also found that the antiviral agent ganciclovir successfully prevented the production of structural proteins by the virus, although it did not ... -University of Virginia

Basic Science Investigation  Jul 3, 2006
2- 18 F-fluoroethyl-L-tyrosine ( 18 F-FET), and 18 F-FDG for monitoring tumor responses during prodrug activation gene therapy with HSV1-tk and ganciclovir (GCV ... -Journal of Nuclear Medicine (subscription)

Basic Science Investigation  Jul 3, 2006
...and quantitative in vivo monitoring using PET of a commonly applied GDEPT, based on herpes simplex virus thymidine kinase type 1 (HSVtk) and ganciclovir (GCV). ... -Journal of Nuclear Medicine (subscription)



New findings in ovarian cancer described from the People's ...  May 11, 2006
..."Because the efficacy of genetic prodrug activation therapy (GPAT) using herpes simplex virus thymidine kinase (tk)/ganciclovir (GCV) or Escherichia coli ... - Therapeutics Daily (subscription)

Serial In Vivo Imaging of the Lung Metastases Model and Gene ...  Apr 26, 2006
...administered HSV1-tk–expressing NG4TL4 fibrosarcoma cells (NG4TL4-TK) and simulated the clinical application of HSV1-tk plus ganciclovir (GCV) prodrug ... - Journal of Nuclear Medicine

Hybrid Virus Targets Cancer Cells  Apr 21, 2006
...the researchers created an AAVP construct that contained the HSVtk gene, which acts as a ''suicide'' gene when combined with Cytovene (ganciclovir) or as a ... - MedPage Today





Controlling the Troll  Mar 20, 2006
Acyclovir is clearly less potent than ganciclovir (3) and is never used for preemptive therapy or therapy of established CMV disease, but as Kalil and ... - Annals of Internal Medicine

Strategies To Prevent Organ Disease by Cytomegalovirus in Solid ...  Mar 20, 2006
...preemptive therapy. Of interest, both of these studies have the words "preemptive ganciclovir therapy" in their titles. After considering ... - Annals of Internal Medicine

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