Recent news on Glucagon

Coffee consumption may lower blood uric acid levels -- The ...  -  25 May 2007
YubaNet,...in another study decaffeinated coffee seemed to delay intestinal absorption of glucose and increase concentrations of glucagon-like peptide 1,

Coffee Consumption May Lower Blood Uric Acid Levels -- The ...  -  25 May 2007
DentalPlans.com,...in another study decaffeinated coffee seemed to delay intestinal absorption of glucose and increase concentrations of glucagon-like peptide 1,

‘Baby Steps’ For Marcadia in Indiana Grow Into ‘Giant Leaps’  -  May 22, 2007
MidwestBusiness.com,The company’s initial product in development is a synthetic glucagon analog that can be used in emergency situations to treat hypoglycemia.

Mutant night-owl gene found  -  May 22, 2007
National Review of Medicine,The drug, which is based on a chemical used in the Gila monster's digestion called exendin-4, works by stimulating beta cells, suppressing glucagon

Invent Now 2007 Winners: Simple Shot Syringe  -  May 16, 2007
Medgadget.com,The inventor, Kim Bertron, was inspired to develop the Simple Shot after a stressful experience trying to give her daughter an emergency shot of glucagon

Necessity is the genesis of award-winning invention for ...  -  May 16, 2007
Tallahassee Democrat,...after her daughter, who has Type 1 Diabetes, suffered a severe hypoglycemic episode and Bertron need to give her a life-saving dose of Glucagon.

Marcadia Raises $15M In First Round For Metabolic Programs  -  May 15, 2007
Therapeutics Daily (subscription) (press release),The company's lead compound is a glucagon analogue designed to be supplied in an injector pen, making it available for quick use in emergency treatment

Marcadia Biotech lands $15M in venture funding  -  May 15, 2007
Indianapolis Business Journal,The funding will help Marcadia develop projects including a glucagon analog for emergency treatment of hypoglycemia, the company announced today.

Scientists find elixir of eternal life  -  May 2, 2007
Telegraph.co.uk,All three play an important role in our early development, and then later on in life with the regulation of glucagon, a hormone made by the pancreas that

Roundworm Gene Insight Into Caloric Restriction  -  May 3, 2007
Wired NewsThey are related to glucagon, a pancreatic hormone that increases blood sugar concentration and maintains the body's energy balance, particularly during

The Modern Marvels Invent Now(R) Challenge Names Top Invention of 2007  -  May 11, 2007
PR Newswire (press release),Her daughter, who has Type 1 Diabetes, was suffering from a severe hypoglycemic episode and Bertron needed to administer a life-saving dose of Glucagon.

Why Calorie Restriction Might Prolong Life  -  May 18, 2007
The Ledger,These genes belong to the Foxa family, and all are involved in regulating glucagon, a hormone produced by the pancreas that contributes to maintaining the

Insulin therapy for diabetes  -  May 16, 2007
Chennai Online,It suppresses glucagon production by the pancreas. Glucagon is responsible for stimulation of liver to produce glucose under normal circumstances.

A Lean Gene for Low-Cal Longevity  -  May 2, 2007
Scientific AmericanGlucagon counters the ill effects of fasting by increasing blood sugar and controlling energy balance. He cautions that the benefits of dietary restriction

Scientists unlock key to longer lifespan  -  May 2, 2007
Telegraph.co.uk,All three play an important role in development and then later on in the regulation of glucagon, a hormone made by the pancreas that unlike insulin

Gastric Bypass Surgery Being Considered as Treatment for Type 2  -  May 19, 2007
Diabetes Health (press release),Other peptides secreted by intestinal cells, including glucagon-like peptide 1 (GLP-1), increase after the operation. (GLP-1 is the protein that Byetta

New injectable treatment for type II diabetes  -  Apr 26, 2007
Healthcare RepublicExenatide also suppresses glucagon secretion, lower concentrations of which lead to decreased hepatic glucose output. It also slows emptying of food from

Geron says embryonic stem cells produce insulin  -  May 18, 2007
ABC NewsIn lab dishes, these cells produced insulin, glucagon and somatostatin, three of the major hormones produced by islet cells. The cells secreted insulin when

Marcadia to use new cash for development  -  May 16, 2007
Indianapolis Star,That money is being used to develop and market DiMarchi's latest invention -- a synthetic glucagon analog that dissolves easily and maintains its structural

Geron Scientists and Collaborators Differentiate Human Embryonic ...  -  May 17, 2007
PharmaLive.com (press release),Geron's scientists and collaborators produced ILCs containing individual cells types that express insulin, glucagon and somatostatin, three of the major

Marcadia Biotech Completes $15 Million Series A Financing  -  May 15, 2007
PharmaLive.com (press release),..."This includes the company's first compound in development, a glucagon analog that will be supplied in an injector pen, making it ready for quick use in

School nurse humbled by honor  -  May 15, 2007
Albany Democrat Herald,...regular classroom teachers — how to monitor catheters, clean tracheotomy openings, adjust gastrointestinal “g-tubes,� mix and inject glucagon,

Lizard lifeline for diabetics  -  May 9, 2007
Persian Journal,A chemical in the Monster's saliva, exendin-4, was found to act in a similar way to the human hormone glucagon-like-peptide-1 (GLP-1).

Want to live longer? Eat less  -  May 8, 2007
Economic Times,These genes say the researchers are related to glucagon, a pancreatic hormone that increases blood sugar concentration and maintains the body’s energy

Negative Health Myths About Coffee Drinking No Longer So Controversial  -  May 8, 2007
Nutrition horizon (press release),...glucose absorption and by stimulating the secretion of the gut hormone glucagon-like peptide-1 (GLP-1) that is beneficial for the secretion of insulin.

Lizard's spit leads to diabetes drug  -  May 7, 2007
Telegraph.co.uk,A chemical in the lizard’s saliva called exendin-4 was shown to act in a similar way to the human hormone glucagon-like-peptide-1 (GLP-1).

1 From the Division of Endocrinology, Children's Hospital Boston ...  -  May 8, 2007
Am J Clin Nutr (subscription),TCF7L2 affects the Wnt signaling pathway and may be critical for glucagon-like peptide 1 (GLP-1) secretion by intestinal endocrine L cells.

Lizard’s poison may be boon for diabetics  -  May 7, 2007
The Herald,The chemical in its saliva, exendin-4, was found to act in a similar way to the human hormone glucagon-like peptide-1 (GLP-1).

Opexa Therapeutics to Present Progress on Development of Monocyte ...  -  May 7, 2007
PharmaLive.com (press release),These insulin-producing, islet-like clusters express insulin, glucagon and somatostatin characteristic hormones found in pancreatic islets and function in a

Gene links up to low-cal diet, longer lifespan  -  May 3, 2007
Economic Times,They are related to glucagon, a pancreatic hormone that increases blood sugar concentration and maintains the body’s energy balance, particularly during

Reducing Food Intake Slows Aging  -  May 4, 2007
eMaxHealth.com,Foxa family members have important roles during development, but also act later in life to regulate glucagon production and glucose homeostasis,

Dose-Response Effects of Free Fatty Acids on Glucose and Lipid ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,...was blocked by acipimox; and endogenous GH, insulin, and glucagon secretion was blocked by somatostatin and subsequently replaced at fixed rates.

Scientists Find Clue To Longevity Hidden In Worm Gene  -  May 4, 2007
Medical News Today,But the Foxa genes also have a role in later life: they help to regulate glucagon, which, unlike insulin, increases blood sugar and maintains the body's

Clinical trial backs Fabuless efficacy  -  May 4, 2007
NutraIngredients-usa.com,An increase in the glucagon like peptide-1 (GLP-1) values two hours after yoghurt consumption was also observed for this group.

Longevity uncovered  -  May 3, 2007
Belfast Telegraph,In mammals, the gene is linked with a hormone called glucagon which increases levels of glucose in the bloodstream to maintain the body's energy balance

Eat Less, Live Longer? Gene Links Calorie Restriction To Longevity  -  May 2, 2007
Science Daily (press release)All three play an important role in development and then later on in the regulation of glucagon, a pancreatic hormone that unlike insulin increases the

New injectable treatment for type II diabetes  -  26 Apr 2007
Healthcare RepublicExenatide also suppresses glucagon secretion, lower concentrations of which lead to decreased hepatic glucose output. It also slows emptying of food from

DiObex Announces the Appointment of David Cory as Chief Executive ...  -  Apr 23, 2007
PR Newswire (press release),DIO-901 is a formulation of Very Low Dose Glucagon (VLD Glucagon) for the prevention of insulin induced hypoglycemia. DIO-901 has received Fast Track status

The Incretin Saga: Mimetics, Enhancers, and Inhibitors  -  Apr 20, 2007
Diabetes Health (press release),The star incretin in diabetes treatment, and our hero in this little tale, is glucagon-like peptide-1, or GLP-1. After a meal, the gut secretes GLP-1 in

Diobex Raises $24 Million Series B Financing Led by Inventages ...  -  Apr 16, 2007
PR Newswire (press release),Very Low Dose (VLD) Glucagon will facilitate intensification while mitigating the attendant risk of hypoglycemia. DiObex has completed three pharmacokinetic

‘No brainer’ still finds opposition  -  Apr 7, 2007
Providence Journal (subscription),And everywhere he goes he carries Glucagon. It’s the drug for emergencies, for the possibility that he will lose consciousness from low blood sugar.

Emisphere Technologies, Inc. Reports Clinical Data On Oral ...  -  Mar 31, 2007
Medical News Today (press release),The objective of the study with glucagon-like peptide-1 (7-36 amide) (GLP-1) was to establish the initial pharmacological profile and the insulin releasing

The Dipeptidyl Peptidase IV Inhibitor Vildagliptin Suppresses ...  -  Apr 4, 2007
Journal of Clinical Endocrinology and Metabolism,Aims/Hypothesis: Vildagliptin is a selective dipeptidyl peptidase IV inhibitor that augments meal-stimulated levels of biologically active glucagon-like

Constitutional thinness and lean anorexia nervosa display opposite ...  -  Apr 5, 2007
Am J Clin Nutr (subscription),...the arcuate nucleus through integration of peripheral hormonal signals such as leptin, ghrelin, peptide YY (PYY), and glucagon-like peptide 1 (GLP-1).

Diabetes and Incretin-based Therapy  -  Apr 4, 2007
Journal of Clinical Endocrinology and Metabolism,Decreasing glucagon release (Glucagon is a hormone that controls the release of glucose, or sugar, from the liver after meals.)

Pancreatic Cells Show Variable Plasticity  -  Apr 7, 2007
Medical News Today (press release),...hormones that control the amount of glucose that is in our blood, including beta cells, which produce insulin, and alpha cells, which produce glucagon.

Emisphere Surges on Drug Delivery Tech  -  Mar 29, 2007
Houston Chronicle,In one study, the company's eligen drug delivery technology was shown to help significantly in insulin production when an oral form of glucagon-like

A Milestone Change in Practice  -  Apr 11, 2007
EMS Magazine,You quickly administer glucagon 1 mg intramuscular and attempt to establish an IV. After two attempts on the flailing child with no veins, you give up.

Emisphere Technologies Reveals Clinical Data On Oral Delivery Of ...  -  Mar 29, 2007
Trading Markets,The company said the objective of the study with glucagon-like peptide-1 was to establish the initial pharmacological profile and the insulin releasing

AACE: Liraglutide Improves Beta-Cell Insulin Secretion  -  Apr 21, 2007
MedPage Today,Liraglutide is a synthetic analog of glucagon-like peptide-1 (GLP-1), a naturally occurring hormone that is released from the gastrointestinal tract on

Exenatide in Combination Therapy: Small Study, Big Market, and ...  -  Apr 2, 2007
Annals of Internal Medicine...emptying but also in the pancreas by stimulating glucose-dependent insulin secretion, promoting insulin biosynthesis, and inhibiting glucagon secretion.

Diobex Announces Successful Completion Of Phase 2a Trial Of DIO ...  -  Mar 28, 2007
Medical News Today (press release),DIO-901 is a formulation of Very Low Dose Glucagon (VLD Glucagon) for reducing or preventing of insulin induced hypoglycemia. DIO-901 has received Fast

MSD's Januvia launches in UK  -  Apr 20, 2007
Pharma Times (subscription),...to promote insulin secretion by the pancreas and inhibit glucagon production, the latter resulting in reduced glucose production by the liver.

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,In addition it decreases glucagon release from the alpha cells of the pancreas. Janumet adds the capability of metformin in suppressing glucose production

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,The hormone also suppressed glucose production by the liver (by diminishing the production of glucagon by the alpha cells of pancreas).

DiObex Closes $24 Mln Series B Financing; To Use Funds To Progress ...  -  Apr 16, 2007
Trading Markets,One of the drug candidates involved in the Phase II clinical trial is DIO-901, which is a formulation of Very Low Glucagon for mitigating hypoglycemia that

Snohomish gets one last chance to have paramedics  -  Apr 13, 2007
KOMO,..."Because they would be completely unable to give me what's called a glucagon shot. And the shot is the last resort before I go into a diabetic coma," said

Gastric Bypass Surgery Explored as Cure for Type 2 Diabetes  -  Apr 13, 2007
Medscape (subscription)Other peptides, including the distal small intestine hormone peptide YY (PYY), and glucagon-like peptide 1 (GLP-1), secreted by intestinal L cells,

Remarkable Natural Polyunsaturated Fatty Acid Stops Hunger in Its ...  -  Apr 13, 2007
PR.com (press release),Pinolenic Acid has been show in human studies to increase cholecystokinin (CCK) by 60% and glucagon-like peptide (GLP-1) by 25% for up to 4 hours.

AACE: Surgery Proposed for Intractable Type 2 Diabetes  -  Apr 12, 2007
MedPage Today,...of a 10 cm to 20 cm segment of the distal ileum, complete with its blood supply and reservoir of glucagon-like peptide 1 (GLP-1)-secreting cells.

Lipid Nutrition builds science behind Clarinol CLA  -  Apr 12, 2007
NutraIngredients-usa.com,The pine nut extract is reported to function by boosting the expression of the appetite-suppressing hormones (glucagon-like peptide-1) GLP-1 and

Cytokine Blocker Eases Beta Cell Stress in Type 2 Diabetes  -  Apr 11, 2007
MedPage Today,...had an oral glucose-tolerance test, followed by an IV bolus of 0.3 g of glucose per kilogram of body weight, 0.5 mg of glucagon, and 5 g of arginine.

Interleukin-1–Receptor Antagonist in Type 2 Diabetes Mellitus  -  Apr 11, 2007
New England Journal of Medicine (subscription),...oral glucose-tolerance test, followed by an intravenous bolus of 0.3 g of glucose per kilogram of body weight, 0.5 mg of glucagon, and 5 g of arginine.

Metabolic effects of amino acid mixtures and whey protein in ...  -  Apr 5, 2007
Am J Clin Nutr (subscription),...and insulinemic responses closely mimicking those seen after whey ingestion in the absence of an additional effect of GIP and glucagon-like peptide 1.

Insulin Analogs or Premixed Insulin Analogs in Combination With ...  -  Apr 17, 2007
Medscape (subscription)New therapies for type 2 diabetes based on glucagon-like peptide 1. Cleve Clin J Med. 2006;73:382-389. Abstract. Ahren B. Vildagliptin: an inhibitor of

Why didn'tI think of that?  -  Apr 5, 2007
Belleville News-Democrat,..."An injection of glucagon had to be administered immediately, but, shaking with fear and adrenaline, I broke the needle while trying to insert it through

Fresh hope for obesity cure from early trials of diabetic treatment  -  Apr 4, 2007
Business Online,Liraglutide is one of a new generation of diabetes medicines based on glucagon like peptide-1 (GLP-1), a hormone that occurs naturally in the human

FDA Approves JANUMET(TM) for Type 2 Diabetes, Offering Powerful ...  -  Apr 2, 2007
PipelineReview.com (press release),...increasing the synthesis and release of insulin from the pancreatic beta cells and decreasing the release of glucagon from the pancreatic alpha cells.

Slimming Ingredients awards science in Berlin  -  Apr 2, 2007
NutraIngredients-usa.com,...tree (Pinus koraiensis) was found to boost expression of the appetite-suppressing hormones (glucagon-like peptide-1) GLP-1 and cholecystokinin (CCK).

Companies talk science of slimming ingredents  -  Mar 30, 2007
NutraIngredients-usa.com,...short-chain fatty acids, with other studies suggesting that this process may enhance expression of the appetite-suppressing glucagon-like peptide-1.

Market Report -- In Play (EMIS)  -  Mar 29, 2007
MSN MoneyThe objective of the study with glucagon-like peptide-1 was to establish the initial pharmacological profile and the insulin releasing activity of

Intarcia Raises $50 Million in a Series BB Financing  -  Mar 28, 2007
Drug Newswire (press release),The type 2 diabetes program involves the delivery of GLP-1 (glucagon-like peptide-1) on a continuous basis through the use of the DUROS delivery technology.

Diobex Announces Successful Completion of Phase 2a Trial Of DIO ...  -  27 Mar 2007
PR Newswire (press release),DIO-901 is a formulation of Very Low Dose Glucagon (VLD Glucagon) for reducing or preventing of insulin induced hypoglycemia. DIO-901 has received Fast

FDA Chief: Biogenerics will be Similar, Not Interchangeable  -  27 Mar 2007
Patent Baristas,FDA has approved other follow-on protein products under section 505 of the Food, Drug, and Cosmetic Act. These include GlucaGen (glucagon recombinant for

Diabetics lobby for lifesaving-injection bill  -  Mar 24, 2007
SalemNews.com,He favors a bill that allows trained nonmedical school staff to administer glucagon to diabetic students in emergencies. "My nephew got diabetes when he was

Glycemic Thresholds for Activation of Counterregulatory Hormone ...  -  Mar 6, 2007
Journal of Clinical Endocrinology and Metabolism,The magnitude of the glucagon and epinephrine responses in the islet transplant group, although greater than in the type 1 diabetes group (P < 0.05 for

Lilly President concerned over R&D threat to UK  -  Mar 1, 2007
Pharma Times (subscription),..."Byetta works in a similar way to the human incretin hormone glucagon-like peptide-1 (GLP-1) by stimulating insulin production only when the blood sugar is

Dr. White Answers Your Medication Questions  -  Mar 24, 2007
Diabetes Interview,It also blocks the effect of glucagon, which is another hormone and one that increases blood sugar. It delays food from being absorbed by slowing stomach

Delta Burke to Americans: Let's Talk about Managing Diabetes  -  Mar 22, 2007
Drug Newswire (press release),BYETTA exhibits many of the same effects as the human incretin hormone glucagon like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through

Effect of dairy calcium or supplementary calcium intake on ...  -  Mar 7, 2007
Am J Clin Nutr (subscription),Concentrations of plasma total triacylglycerol, chylomicron triacylglycerol, serum total cholesterol, HDL cholesterol, cholecystokinin, glucagon-like

The New Class of Dipeptidyl Peptidase IV (DPP-IV) Inhibitors Has ...  -  Mar 5, 2007
PR.com (press release),Dipeptidyl peptidase IV is an enzyme that rapidly inactivates the insulinotropic hormone glucagon-like peptide-1 (GLP-1). Inhibition of dipeptidyl peptidase

Intarcia Raises $50 Million in a Series BB Financing  -  Mar 19, 2007
PR Newswire (press release),The type 2 diabetes program involves the delivery of GLP-1 (glucagon-like peptide-1) on a continuous basis through the use of the DUROS delivery technology.

Caregiving: Delta Burke on diabetes  -  Mar 16, 2007
Earthtimes.orgIncretin mimetics are a new class of drugs that exhibit many of the same effects as the human incretin hormone glucagon, which improves blood sugar after

Isis Pharmaceuticals Reports Financial Results and Highlights for ...  -  Mar 8, 2007
Earthtimes.orgIn our diabetes program, we initiated IND-enabling toxicology studies for ISIS 325568, our antisense drug targeting the glucagon receptor,

Taser response to diabetic reviewed in Ore.  -  Mar 14, 2007
JEMS.com,Family members are often instructed to try to restrain the person in order to give an injection of glucagon, a hormone.

It comes down to satisfaction  -  Mar 10, 2007
Los Angeles Times,Other appetite-dampening hormones that may be involved are leptin (made in fat cells) as well as glucagon-like peptide-1 and cholecystokinin,

GSK erodes pipeline across several areas  -  Mar 5, 2007
DrugResearcher.com,...albiglutide, which is a glucagon-like peptide activator for the treatment of Type II diabetes; 364735, an HIV integrase inhibitor; and 649868,

Incretin mimetics vie for slice of type 2 diabetes market  -  Mar 1, 2007
Nature.com (subscription),Pennsylvania, with a strong product pipeline in type 2 diabetes, including long-acting agonists of glucagon-like peptide 1 (GLP-1) receptor,

Ajinomoto ups L-Arginine price  -  Feb 27, 2007
In-PharmaTechnologist.com,...helping remove excess ammonia from the body, and promoting secretion of several hormones, including glucagon, insulin, and growth hormone.

Molecular evidence that the body's internal clock controls blood ...  -  Feb 26, 2007
TheHeart.Org,They had assumed that this occurred by abolishing the counterregulatory hormone response—glucagon and steroids—that are turned on in response to

New Storage Instructions Approved For BYETTA®  -  Feb 25, 2007
Medical News Today (press release),BYETTA exhibits many of the same effects as the human incretin hormone glucagon-like peptide-1 (GLP-1). GLP-1 improves blood sugar after food intake through

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