Recent news on Granulocyte

Micromet Could Earn $167M in Alliance with Nycomed  -  25 May 2007
Genetic Engineering News (press release),The lead product candidate is Micromet's MT203, a human antibody that neutralizes granulocyte macrophage colony-stimulating factor (GM-CSF).

... Go to the Article  -  May 1, 2007
CancerWiseThe MD Anderson study is the first phase II clinical trial to pair trastuzumab with granulocyte-macrophage colony-stimulating factor (GM-CSF),

Humanised mouse 'far more useful' to predict side effects  -  May 22, 2007
LabTechnologist.com,This is done by combining two genes together: the granulocyte-macrophage colony-stimulating factor (GM-CSF) gene to attract antigen-presenting cells to

For sale: Stem cell enhancers  -  May 15, 2007
Scientist,There are other stem cell enhancing drugs that target particular cell types, such as granulocyte colony-stimulating factor, which elevates white blood cells

To Build a Killing Machine  -  May 9, 2007
Scientist,In JX-594 and JX-929, granulocyte monocyte-colony stimulating factor (GM-CSF), is intended to stimulate white blood cell production.

Wockhardt reinforces European presence with Negma acquisition  -  May 9, 2007
OutSourcing-Pharma.com,...erythropoietin, hepatitis B vaccine, interferon alpha 2B, Glargine (long-acting insulin) and granulocyte-colony stimulating factor (G-CSF).

Small players make it big with off-patent drugs  -  Apr 29, 2007
Business Standard,Intas Biopharmaceuticals, another emerging player, already markets indigenously developed biopharmaceutical products such as recombinant human Granulocyte

Dose modification associated with poorer response to HCV therapy ...  -  Apr 29, 2007
Aidsmap,...hepatitis C therapy, dose reduction, or the use of supporting therapies such as erythropoietin (EPO) and granulocyte-colony-stimulating factor (G-CSF).

CoGenesys, Inc. Expands Clinical Programs with Initiation of Phase ...  -  Mar 27, 2007
PipelineReview.com (press release),CoGenesys, Inc. announced today that the Company has initiated a Phase 1-2a study in Europe of Neugranin(TM), a long-acting form of Granulocyte Colony

CoGenesys Expands Clinical Programs with Initiation of Phase 1-2a ...  -  Mar 27, 2007
PR Newswire (press release),CoGenesys is also developing Neugranin(TM), a long-acting form of Granulocyte Colony Stimulating Factor (G-CSF), now in clinical testing as a treatment to

CoGenesys begins research on infection drug  -  Mar 28, 2007
Pharmaceutical Business ReviewNeugranin is a long-acting form of Granulocyte Colony Stimulating Factor (G-CSF). CoGenesys believes that Neugranin has the potential to be the second

An Update on Transcription Factors in Asthma  -  Apr 23, 2007
Medscape (subscription)In vitro studies have shown that IL-17 induces IL-6, production of granulocyte colony-stimulating activity, and chemokine production.

Cleveland BioLabs Protectan CBLB612 Demonstrates Efficacy In ...  -  Apr 21, 2007
Medical News Today (press release),A common current therapeutic approach for increasing the amount of hematopoietic stem cells in blood is multiple injections of granulocyte-colony

Cell Genesys immunotherapy is patiently specific  -  Apr 19, 2007
LabTechnologist.com,The cells secrete the immune stimulatory hormone, GM-CSF (granulocyte-macrophage colony stimulating factor) to encourage immune cells to attack cancer cells

Latest in Haematology analysers: Fluorescence Flow Cytometry  -  Apr 19, 2007
Express Healthcare Management,The major benefit of FCM to its users is improved detection of pathological cells like Immature Granulocyte Count, High Fluorescence Lymphocyte Count,

Cell Genesys reports data from clinical trials of GVAX ...  -  Apr 18, 2007
News-Medical.net,GVAX immunotherapy for prostate cancer is comprised of two prostate cancer cell lines that have been modified to secrete GM-CSF (granulocyte-macrophage

Stem Cell Transplants not Superior to Intensive Adjuvant Therapy ...  -  Apr 17, 2007
Cancer Consultants (press release),...thiotepa, carboplatin) or 9 cycles of tailored FEC with granulocyte colony-stimulating factor (Neupogen®) support. There were 104 cancer relapses in the

The alcoholic lung: epidemiology, pathophysiology, and potential ...  -  Apr 11, 2007
AJP-Lung Physiology (subscription)Granulocyte/macrophage colony-stimulating factor or GM-CSF is a 23-kDa glycosylated monomeric peptide secreted by multiple cell types, including the

Autologous Nonmyeloablative Hematopoietic Stem Cell ...  -  Apr 10, 2007
Journal of American Medical Association (subscription),Hematopoietic stem cells were mobilized with cyclophosphamide (2.0 g/m 2 ) and granulocyte colony-stimulating factor (10 µg/kg per day) and then collected

Billion dollar babies—biotech drugs as blockbusters  -  Apr 3, 2007
Nature.com (subscription),The FDA approved the first biotech blockbusters, Epogen and Neupogen (filgrastim, Amgen's recombinant granulocyte-colony stimulating factor prescribed for

Cell Genesys shares soar over promising cancer immunotherapy data  -  Apr 4, 2007
Pharma Times (subscription),GVAX immunotherapy is comprised of two prostate cancer cell lines that have been modified to secrete GM-CSF (granulocyte-macrophage colony stimulating

3SBio Inc. Announces Fourth Quarter And Fiscal Year 2006 Results  -  Apr 5, 2007
Drug Newswire (press release),Tietai Iron Sucrose Supplement and Baolijin, our recombinant human granulocyte colony-stimulating factor or G-CSF, in-licensed in May and August 2006,

3SBio Inc. Announces Fourth Quarter And Fiscal Year 2006 Results  -  Apr 2, 2007
Genetic Engineering News (press release),Supplement and Baolijin, our recombinant human granulocyte colony-stimulating factor or G-CSF, in-licensed in May and August 2006 , respectively.

FDA Chief: Biogenerics will be Similar, Not Interchangeable  -  27 Mar 2007
Patent Baristas,EMEA has issued these annex guidelines on human growth hormone, recombinant erythropoietins, recombinant granulocyte-colony stimulating factor and

BioGeneriX and Neose Announce Initiation of 2nd Phase I Clinical ...  -  Mar 21, 2007
PipelineReview.com (press release),...today announced that the second Phase I clinical trial of GlycoPEG-GCSF, a long acting granulocyte colony stimulating factor (GCSF), has been initiated.

Transplant girl Sorrell continues to progress  -  Mar 24, 2007
Cambridge Evening News,Granulocyte donation is not standard treatment in bone marrow transplants - Bristol is the only place in the country where it can be done.

Breast cancer chemo can carry leukemia risk  -  Mar 16, 2007
The Australian,Growth factors such as G-CSF (granulocyte colony-stimulating factor), and GM-CSF (granulocyte-macrophage colony-stimulating factor) boost the patient's

Biotech Day In Review: BioSimilar Cancer Drug Enters Trial  -  Mar 22, 2007
Seeking Alpha,...which will be compared to Amgen’s (AMGN) Neulasta, the only currently approved long-acting granulocyte colony stimulating factor [GCSF].

Relationship between Adipocyte Size and Adipokine Expression and ...  -  Mar 6, 2007
Journal of Clinical Endocrinology and Metabolism,...macrophage inflammatory protein-1ß, granulocyte colony stimulating factor, IL-1ra, and adiponectin was positively correlated with cell size.

In search of a matching donor  -  Mar 21, 2007
Excalibur Online,To increase cell development, doctors inject donors with granulocyte colony stimulating factor (G-CSF) everyday for four to five days.

In a grateful vein  -  Mar 21, 2007
phillyBurbs.com,In addition to regular whole- blood donations, Newbert also donates platelets (which help the blood to clot) and granulocyte (a white blood cell that fights

Epirubucin-Docetaxel Shows Early Promise in Inflammatory Breast ...  -  Mar 20, 2007
DG NewsIn all, 69% of patients received granulocyte colony stimulating factor for neutropenia. However, no patient developed febrile neutropenia in more than 1

Testing Adult Stem Cells For Heart Damage Repair  -  Mar 15, 2007
Medical News Today (press release),...typically delivered under the skin in the arm, thigh or abdomen of a commercially produced protein (granulocyte colony stimulating factor).

Autograft-Allograft Tandem Improves Multiple Myeloma Survival  -  Mar 15, 2007
MedPage Today,This group also received 5 μg of granulocyte-colony stimulating factor per kilogram from day one or three, until neutrophil counts above 1000 per mm 3 were

Roche Ending Maxygen Deal For Factor VII Over De-Risk'  -  Mar 14, 2007
BioWorld Online,Separately Wednesday, Maxygen disclosed Phase I results with MAXY-G34, a next-generation granulocyte-colony stimulating factor (G-CSF) product for

US biogenerics bill sponsor says EU way is "burdensome  -  Mar 13, 2007
Pharma Times (subscription),However, more applications are already in the pipeline, mainly concerning erythropoietins, interferons, insulins and granulocyte colony stimulating factors,

Testing new waters  -  Mar 5, 2007
Financial Express,Other products include growth hormones, Granulocyte Stimulating Factor, Follicle Stimulating Factor, Blood Factor VIII, Tissue Plasmogen Activator and

Natural supplement can boost your stem-cell count  -  Feb 28, 2007
Canadian Jewish News,...“There is a compound injected in the blood called G-CSF, granulocyte colony-stimulating factor, which stimulates the release of stem cells from the bone

Cell Genesys and Medarex Announce Encouraging Follow-Up Results ...  -  Feb 26, 2007
Drug Newswire (press release),GVAX immunotherapy for prostate cancer is comprised of two prostate cancer cell lines that have been modified to secrete GM-CSF (granulocyte-macrophage

Stroma-derived factor (SDF-1/CXCL12) and human tumor pathogenesis  -  Mar 8, 2007
AJP - Cell Physiology (subscription)...and CD4 + Treg cell release from bone marrow is achieved through granulocyte-colony-stimulating factor reducing marrow expression of CXCL12 (153).

Role of Granulocyte Macrophage Colony-Stimulating Factor in Host ...  -  Feb 23, 2007
Am J Pathology (subscription)We investigated the role of granulocyte macrophage colony-stimulating factor (GM-CSF) in host defense in a murine model of pulmonary cryptococcosis induced

Growth Factors Commonly Given With Chemotherapy Associated With ...  -  Feb 7, 2007
DG NewsThe growth factors granulocyte or granulocyte-macrophage colony-stimulating factor (G-CSF or GM-CSF) have been used to reduce the risk of infections from

Breast cancer treatment found to boost leukemia risk  -  Feb 7, 2007
Los Angeles Times,Growth factors such as G-CSF (granulocyte colony-stimulating factor), known by the trade name Neupogen, and GM-CSF (granulocyte-macrophage

Infection-Fighting Cancer Treatment Could Boost Leukemia Risk  -  Feb 7, 2007
HealthCentral.com,Of the total, 906 women received either granulocyte colony-stimulating factor (G-CSF) or granulocyte-macrophage colony-stimulating factor (GM-CSF), or both.

Cell Genesys And Medarex Announce Encouraging Follow-Up Results ...  -  Feb 23, 2007
Medical News Today (press release),GVAX immunotherapy for prostate cancer is comprised of two prostate cancer cell lines that have been modified to secrete GM-CSF (granulocyte-macrophage

Cell Genesys and Medarex Announce Encouraging Follow-Up Results ...  -  Feb 22, 2007
PharmaLive.com (press release),GVAX immunotherapy for prostate cancer is comprised of two prostate cancer cell lines that have been modified to secrete GM-CSF (granulocyte-macrophage

Growth Factors May Increase Risk of AML and MDS in Post-menopausal ...  -  Feb 15, 2007
Cancer Consultants (press release),Acute myeloid leukemia or myelodysplastic syndrome following use of granulocyte colony-stimulating factors during breast cancer adjuvant chemotherapy.

Favrille Announces Agreement With Berlex, Inc. Regarding Use of ...  -  Feb 14, 2007
PharmaLive.com (press release),Leukine is a recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF), a growth factor that is currently used to help fight infections in

Candida glabrata, an Emerging Oral Opportunistic Pathogen  -  Feb 21, 2007
Journal of Dental Research (subscription),With the exception of granulocyte monocyte colony-stimulating factor, C. glabrata triggers a lower proinflammatory cytokine response in oral epithelial

Growth Factors for Breast Cancer Linked to Leukemia  -  Feb 7, 2007
MedPage Today,The relative risk of the two conditions for women 65 or older treated with either granulocyte colony stimulating factor (G-CSF) or granulocyte-macrophage

French law disallows 'generic' biosimilars  -  Feb 20, 2007
OutSourcing-Pharma.com,...interferon alpha, interferon beta, insulin, erythropoietin, and granulocyte-colony stimulating factor) will generate savings of around €2bn-€3bn a year.

US law promises new biz avenue for India  -  Feb 18, 2007
Central Chronicle,Zenotech Laboratories to produce its first biosimilar, a Granulocyte-colony stimulating factor (G-CSF; filgrastim) for chronic renal failure.

Immatics Biotech Raises $52M For Cancer Vaccines  -  Feb 13, 2007
BioWorld Online,The peptides are administered, along with an adjuvant such as Granulocyte Macrophage Colony-Stimulating Factor, via injection into the skin.

Studies Examine Breast Cancer Therapy, Effect Of Vitamin D On ...  -  Feb 13, 2007
Medical News Today (press release),..."Acute Myeloid Leukemia or Myelodysplastic Syndrome Following Use of Granulocyte Colony-Stimulating Factors During Breast Cancer Adjuvant Chemotherapy,"

Indian-Irish biosimilar partnership to provide new European CMO ...  -  Feb 13, 2007
OutSourcing-Pharma.com,...hepatitis B-and C treatment interferon-alfa, and granulocyte colony stimulating factor (G-CSF) - used to treat chemotherapy-induced neutropaenia.

Lung Cancer Patients More Likely to be Eligible for Surgery After ...  -  Feb 9, 2007
DG News...carboplatin AUC 6 on day 2 every 21 days for a total of 2 cycles in combination with granulocyte colony-stimulating factor 300 mcg/m 2 every other day.

Indian firm, Ranbaxy, eyes up biosimilars  -  Feb 9, 2007
BiopharmaReporter.com,...a granulocyte-colony stimulating factor (G-CSF; filgrastim), leading the way for Indian generic chemical-based companies to enter the biologics arena.

Cincinnati Researchers Publish Pioneering Work Characterizing The ...  -  Feb 9, 2007
Medical News Today (press release),8, 2007 edition of the New England Journal of Medicine also highlighted the importance of the immune system regulator Granulocyte-Macrophage-Colony

Reliance Life to put Rs 278 cr in GeneMedix  -  Feb 7, 2007
Business Standard,Its second product granulocyte colony stimulating factor (GCSF), used as an adjunct treatment with chemotherapy for cancer, would be entering the clinical

Growth Factors Associated with Neutrophil Function  -  Feb 8, 2007
MedPage Today,Granulocyte-macrophage colony stimulating factor (GM-CSF) -- which is the target of auto-antibodies in the disease -- plays a central role in neutrophil

CFTR is a modulator of airway inflammation  -  Feb 8, 2007
AJP-Lung Physiology (subscription)Also, CFTR inh -172 did not appear to produce increased IL-8, IL-6, or granulocyte/macrophage colony-stimulating factor secretion in cultured CF-derived

Reliance Life Sciences acquires 74-per cent stake in UK's GeneMedix  -  Feb 8, 2007
domain-B,Another product, granulocyte colony stimulating factor (GCSF), which stimulates white blood cell production, would be entering clinical trials later this

Rel Life may make Irish firm’s drugs  -  Feb 7, 2007
Daily News & Analysis,For RLS, the product basket of GeneMedix, which has drugs like Erythropoietin (EPO), Granulocyte Colony Stimulating Factor (GCSF) and Interferon Alfa,

GM-CSF Autoantibodies and Neutrophil Dysfunction in Pulmonary ...  -  Feb 7, 2007
New England Journal of Medicine (subscription),...alveolar proteinosis occurs in association with high levels of autoantibodies against granulocyte–macrophage colony-stimulating factor (GM-CSF).

Reliance, Ranbaxy enter bio-similar drugs market  -  Feb 7, 2007
Financial Express,GeneMedix has a range of products including EPO (erythropoietin, used in chronic renal failure), G-CSF (Granulocyte Colony-Stimulating Factor),

Breast cancer treatment may be complicated by leukemia risk  -  Feb 7, 2007
HealthandAge.comThat is why growth factors such as granulocyte-colony stimulating factor are often used to protect the cells. But researchers at Columbia University now

Reliance Life Sciences Acquires Genemedix PLC, UK  -  Feb 7, 2007
PR-Inside.com (Pressemitteilung),The second product, Granulocyte Colony Stimulating Factor (GCSF), would be entering the clinical trial stage later this year. GCSF stimulates white blood

Potential for Adult Stem Cells to Repair Hearts Damaged by Severe ...  -  Feb 6, 2007
PressZoom (press release),...typically delivered under the skin in the arm, thigh or abdomen ) of a commercially produced protein ( granulocyte colony stimulating factor ).

Stem Cell Trial With Potential To Repair Hearts Damaged By Severe ...  -  Feb 4, 2007
Medical News Today (press release),...typically delivered under the skin in the arm, thigh or abdomen) of a commercially produced protein (granulocyte colony stimulating factor).

TetraLogic Pharmaceuticals Appoints Dr. Andrew Pecora to Its Board ...  -  Jan 30, 2007
Business Wire (press release),...including clinical trial design, and is a pioneer in the use of Granulocyte Cell Stimulating Factor (GCSF) for the supportive care of cancer patients.

Brain study offers clues into why humans do good  -  Jan 30, 2007
Asbury Park Press,Granulocyte colony-stimulating factor (G-CSF) — a medication commonly used to help reduce the toxic effects of chemotherapy in cancer patients - also caused

Cytokinetics, Incorporated Reports Fourth Quarter and Year End ...  -  Jan 31, 2007
PR Newswire (press release),...one-hour infusion on days 1 and 15 of a 28-day schedule, first without and then with the administration of granulocyte colony stimulating factor (GCSF).

Mitoxantrone-based Therapy Increases Risk for Subsequent Leukemia ...  -  Jan 12, 2007
Cancer Consultants (press release),Patients treated with granulocyte colony-stimulating factor (G-CSF) also appeared to have an increased risk of developing AML or MDS.

Researchers Urge Monitoring Of Bone Health During Chemotherapy  -  Jan 15, 2007
Medical News Today (press release),Weilbaecher and her colleagues found that when they gave mice an eight-day course of the growth factor, called granulocyte colony-stimulating factor (G-CSF)

Telik's Shares Take Tumble On Telcyta Phase III Failures  -  Dec 26, 2006
BioWorld Online,A Phase II oral dosing trial is expected to start next year with the small molecule designed to enhance the production of granulocyte-colony stimulating

Pharma Sector: Few Newsmakers Of The Week - Schwarz Pharma ...  -  Jan 6, 2007
Trading Markets,CoGenesys will be the next to join the bandwagon of companies marketing Granulocyte Colony Stimulating Factor, if it successfully completes the clinical

Dose-Dense Chemotherapy for Osteosarcoma Yields No Survival Benefit  -  Jan 16, 2007
MedPage Today,The latter were condensed into six two-week cycles plus 5 μg/kg granulocyte colony stimulating factor (G-CSF) on days four to 13 of each cycle to increase

Potential for Adult Stem Cells to Repair Hearts Damaged by Severe ...  -  Jan 15, 2007
PharmaLive.com (press release),...typically delivered under the skin in the arm, thigh or abdomen) of a commercially produced protein (granulocyte colony stimulating factor).

CoGenesys Files To Begin Clinical Trials Of Neugranin For The ...  -  Jan 5, 2007
Medical News Today (press release),CoGenesys is also developing Neugranin(TM), a long-acting form of Granulocyte Colony Stimulating Factor (G-CSF), to decrease the incidence of infection in

Dutton Associates Announces Investment Opinion: Chemokine ...  -  Jan 12, 2007
Genetic Engineering News (press release),We were expecting results from both the second and third stage of this study (the third stage combines CTCE-0214 with granulocyte colony stimulating factor

Cancer therapy may weaken bones  -  Jan 12, 2007
United Press InternationalDoctors at Washington University School of Medicine in St. Louis found that, when mice were given drugs known as granulocyte-colony stimulating factors

Cleveland BioLabs Protectans Technology Yields Stem Cell Research ...  -  Jan 11, 2007
Medical News Today (press release),...or mobilized peripheral blood harvesting, is an injection of granulocyte-colony stimulating factor or G-CSF (Neupogen(R), Granocyte(R), Neulasta(R)).

Cleveland Biolabs Stock Moves On Stem Cell Report  -  Jan 10, 2007
Cleveland Leader,...marrow or mobilized peripheral blood harvesting, is an injection of granulocyte-colony stimulating factor or G-CSF (Neupogen®, Granocyte®, Neulasta®).

Follow-Up Data on Dose-Dense Chemotherapy Confirms Benefit in ...  -  Jan 10, 2007
Cancer Consultants (press release),...paclitaxel 225 mg/m2 and cyclophosphamide 2500 mg/m2) administered once every 2 weeks with granulocyte colony stimulating factor (G-CSF) support,

Biotech Stocks Day-in-Review: Amgen Strikes Drug Deal With ...  -  Jan 4, 2007
Seeking Alpha,...has asked European authorities to allow the start of human studies of Neugranin, a long-acting form of Granulocyte Colony Stimulating Factor [G-CSF].

MGI Pharma Announces Publication of Phase 2 Data Describing ...  -  Jan 3, 2007
PharmaLive.com (press release),The use of erythropoietin and granulocyte colony-stimulating factor (G-CSF) were allowed as indicated by the clinical condition. Patients received at least

Research and Markets: Gain an Insight into the Financial ...  -  Dec 20, 2006
PharmaLive.com (press release),Neulasta (pegfilgrastim) is a sustained-duration formulation of Neupogen (filgrastim) formed by the addition of polyethylene glycol to granulocyte colony

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