Recent news on Hmg-Coa

Can Statins Cut Lung Cancer Risk  -  May 22, 2007
DentalPlans.com,These clever drugs achieve their mission by working to block a particular enzyme (called in short HMG-CoA reductase) in the liver, which is needed to

Statins may help treat hepatitis C  -  May 21, 2007
Times of India,Statins or HMG-CoA reductase inhibitors form a class of hypolipidemic agents, used as pharmaceutical agents to lower cholesterol levels in people with or at

Red Rice Yeast a Natural Alternative to Lowering High Cholesterol  -  May 5, 2007
PR Web (press release),The Monacolin-K component found in red rice yeast is acting as the inhibitor of the enzyme known as HMG-Coa reductase, which acts as the cholesterol trigger

Single-tablet combination of atorvastatin and amlodipine for high ...  -  May 16, 2007
News-Medical.net,Atorvastatin (brand name Lipitor) is in a class of medications known as statins or HMG-CoA reductase inhibitors. It lowers the level of cholesterol in the

Up And Down With Cholesterol Management  -  May 4, 2007
Medical News Today (press release),Combining the most potent HMG-CoA reductase inhibitor rosuvastatin and cholesterol absorption inhibitor (CAI) ezetimibe leads to > 70 % reduction of LDL

US FDA approves Ranbaxy's pravastatin sodium tablets  -  Apr 25, 2007
domain-B,Statins reduce cholesterol by inhibiting the enzyme HMG-CoA reductase in the liver that is necessary for the production of cholesterol.

Implications Of Statin Therapy In Bladder Cancer Patients  -  Apr 2, 2007
Medical News Today (press release),The 3-Hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) are widely used in the treatment of hyperlipidemia and,

Samaritan Pharma Partners PII HIV Drug to Pharmaplaz; Upfront ...  -  Mar 28, 2007
PipelineReview.com (press release),SP-01A is a viral replication inhibitor that acts in a dose-dependent manner by reducing the levels of the rate-limiting enzyme HMG-CoA reductase mRNA,

Podcast: Statin drugs — Common side effects  -  Mar 28, 2007
MayoClinic.comRemember I said in the liver where it attacks this enzyme, HMG-CoA reductase, the enzyme that leads to production of cholesterol, with our desired effect at

Primary Prevention of Atherosclerotic Cardiovascular Disease The ...  -  Mar 27, 2007
Journal of American Medical Association (subscription),Morgan T, Evans G, Mudra H. Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors.

Merck and Schering-Plough to Develop Another New Cholesterol ...  -  27 Mar 2007
Genetic Engineering News (press release),Simvastatin Simvastatin reduces cholesterol by inhibiting the conversion of HMG-CoA to mevalonate, an early step in the biosynthetic pathway for cholesterol

Target validation: Determining druggability  -  Mar 2, 2007
Nature.com (subscription),...be explained by a preference for selectivity over affinity, and HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase, the target of the statins.

Primary Prevention of Atherosclerotic Cardiovascular Disease  -  Mar 25, 2007
Journal of American Medical Association (subscription),Morgan T, Evans G, Mudra H. Carotid intimal-media thickness as a surrogate for cardiovascular disease events in trials of HMG-CoA reductase inhibitors.

Drugs that Stop Bad Cholesterol in Different Ways Produce Dramatic ...  -  Feb 27, 2007
SeniorJournal.com,Rosuvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body.

Cholesterol busting statins also reduce blood pressure  -  Mar 11, 2007
SpiritIndia,Statin - Wikipedia, the free encyclopedia - The statins (or HMG-CoA reductase inhibitors) form a class of hypolipidemic agents ... Direct evidence of the

Membrane chaperone Shr3 assists in folding amino acid permeases ...  -  Feb 26, 2007
Journal of Cell Biology (subscription)ER-associated degradation; HMG CoA, 3-hydroxy-3-methylglutaryl coenzyme A; INSIG, insulin-induced gene; PM, plasma membrane; TMS, transmembrane segment.

Lowering LDL Cholesterol -- Beyond Statins  -  Feb 5, 2007
Medscape (subscription)Squalene synthase inhibitors are believed to have potential advantages over statins, which inhibit 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase

Rosuvastatin acts rapidly in acute coronary syndrome  -  Jan 30, 2007
Therapeutics Daily (subscription) (press release),NEW YORK (Reuters Health) - The HMG-CoA reductase inhibitor rosuvastatin exerts rapid immunomodulatory effects on the level of T-cell activation in patients

Heart Your Heart  -  Feb 21, 2007
Knoxville Metro Pulse,This nutrient inhibits HMG-CoA, the enzyme responsible for making cholesterol, and its chemical composition is similar to the "statin" drugs that are

Impact of Splitting Risperidone Tablets on Medication Adherence ...  -  Feb 7, 2007
Psychiatric Services (subscription)Gee M, Hasson NK, Hahn T, et al: Effects of a tablet-splitting program in patients taking HMG-CoA reductase inhibitors: analysis of clinical effects,

Using cholesterol drugs during pregnancy may lead to birth defects  -  Jan 16, 2007
Daily Times,The statins (or HMG-CoA reductase inhibitors) form a class of hypolipidemic agents, used as pharmaceuticals to lower cholesterol levels in people with or at

Statins Not Protective Against Colorectal Cancer  -  Jan 4, 2007
Cancer Consultants (press release),Statins, also referred to as HMG CoA reductase inhibitors, are drugs used to lower cholesterol levels. Laboratory studies have suggested that statins may

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),Simvastatin Simvastatin reduces cholesterol by inhibiting the conversion of HMG-CoA to mevalonate, an early step in the biosynthetic pathway for cholesterol

American Journal of Clinical Nutrition, Vol. 85, No. 1, 293S-299S ...  -  Jan 5, 2007
Am J Clin Nutr (subscription),Williams D, Feely J. Pharmacokinetic-pharmacodynamic drug interactions with HMG-CoA reductase inhibitors. Clin Pharmacokinet 2002;41:343–70.[Medline]

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),...inhibitor of intestinal cholesterol and related phytosterol absorption, and simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor. ...

Lunastatin May Lower LDL Cholesterol  -  Dec 11, 2006
Natural Products Industry Insider,Lunastatin™, from Soy Labs LLC (www.soylabs.com) was found to have inhibited expression of HMG-CoA reductase by 50 percent. Notably ...

Statin users risk myocardial infarction by dropping treatment or ...  -  Dec 14, 2006
Xagena.it,They were also able to compare the preventive effects of different doses and types of statins, also called HMG-CoA reductase inhibitors. ...

Pfizer scraps cholesterol drug  -  Dec 4, 2006
DrugResearcher.com,...blood in two ways. They slow production by inhibiting an enzyme in the liver called HMG-CoA reductase. Statins also increase the ...

The Torcetrapib Catastrophe  -  Dec 3, 2006
Corante,...shock, since we don't know (yet) if the patient deaths were due to CETP inhibition itself, the combination of it with the HMG CoA reductase inhibition of the ...

MEB Netherlands approves Simvastatin Tablets of Aurobindo Pharma  -  Dec 11, 2006
Equity Bulls,Recognition Procedure. Simvastatin is a lipid-lowering agent belonging to a class of medications called HMG-COA reductase inhibitors. The ...

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