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Recent news on Indinavir


PRESIDENT’S ADDRESS AT THE CONVOCATION OF THE PT. BD SHARMA POST ...  -  25 May 2007
Press Information Bureau (press release),Another medicine found is INDINAVIR with equally good results. A foreign University has tried a combination of AZT-INDINAVIR and 3TC, for some patients,

International panel issues new HIV/HCV co-infection guidelines  -  May 24, 2007
Aidsmap,Although atazanavir (Reyataz) and indinavir (Crixivan) can cause elevated bilirubin levels, this does not reflect liver damage.

I've done it. What now?  -  May 23, 2007
Health24.com,In some circumstances, a third drug such as indinavir is added to this treatment. A person who has had occupational exposure to HIV should be managed by

HIV/hepatitis C coinfected may have less risk of lipodystrophy and ...  -  May 21, 2007
Aidsmap,...while indinavir (p = 0.002) was linked with less leg fat in both groups, and nevirapine was linked with more leg fat in coinfected men (p = 0.016).

No major metabolic differences between PI-based and NNRTI-based ...  -  Apr 29, 2007
Aidsmap,Noted study limitations include “the fact that … nelfinavir and indinavir were the primary PIs available; thus, the study does not provide information on

Marijuana Use Does Not Accelerate HIV Infection  -  Mar 31, 2007
PakTribune.com,Although marijuana use did produce a drop in indinavir levels, this fall was small and unlikely to be clinically meaningful. However, it still remained

Narrative Review: Antiretroviral Therapy to Prevent the Sexual ...  -  Apr 16, 2007
Annals of Internal MedicineFor example, male and female genital tract concentrations of protease inhibitors, with the exception of indinavir, are less than 10% and 50% of blood plasma

Broadway Actress/HIV Advocate, Sheryl Lee Ralph, Unveils Winning ...  -  Apr 16, 2007
Drug Newswire (press release),Propulsid(R) (cisapride), Camptosar(R) (irinotecan hydrochloride), Crixivan(R) (indinavir sulfate), Mevacor(R) (lovastatin), Zocor(R) (simvastatin),

Adverse effects of ARVs  -  Apr 1, 2007
ZimDaily,A drug like Indinavir is known to produce kidney stones (so patients have to drink a lot of water) and can also cause hair loss.

Basic research paving way to clinical care  -  Feb 12, 2007
Worcester Telegram,It turns out that HIV-infected people taking drugs such as indinavir have a hard time storing glucose in their cells. The protease inhibitors, while

Data Published In AIDS Show Viramune (nevirapine) Achieves Durable ...  -  Feb 5, 2007
Medical News Today (press release),...nelfinavir (n=135), ritonavir (n=15), saquinavir (n=13), or indinavir or saquinavir in combination with low-dose ritonavir (n=19) prior to study entry.

President's address and interaction with the students of Kurnool ...  -  Feb 2, 2007
Nanotechnology News (press release)Another medicine found is INDINAVIR with equally good results. A foreign University has tried a combination of AZT-INDINAVIR and 3TC, for some patients,

MSD provides relief for Kenya's PLWA  -  Feb 16, 2007
Africa Science News Service,The prices of other formulations of STOCRIN and Merck's other HIV/AIDS medicine, CRIXIVAN (indinavir sulfate), however remain unchanged.

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,Next came HIV protease inhibitors such as Roche's Invirase/Fortovase (saquinavir), Abbott Laboratories Norvir (ritonavir), Merck & Co's Crixivan (indinavir)

Use of d4T is associated with buffalo hump  -  Feb 2, 2007
Aidsmap,...treatment with saquinavir (p = 0.001), indinavir (p = 0.048)), efavirenz (p = 0.032), d4T (p = 0.0001) and tenofovir (p = 0.006).

Be careful if using fosamprenavir/ritonavir for PEP, and did HCV ...  -  Jan 31, 2007
Aidsmap,In December 2003, a 24 year-old gay man was prescribed PEP consisting of Combivir and indinavir (Crixivan) for four weeks following receptive unprotected

Antiretroviral Therapy for HIV: New Data From HIV 8 in Glasgow  -  Dec 26, 2006
Medscape (subscription)However, the MaxCmin 1 study with saquinavir/r vs indinavir/r was one of the first of these trials and found that saquinavir/r outperformed indinavir/r,

Drug-resistant HIV battled in a new way  -  Jan 7, 2007
New Scientist (subscription),A mutation at position 46 makes the virus resistant to the drug indinavir. If the test revealed this mutation, doctors would know not to prescribe that drug

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),...or fenofibrate) -- the antibiotics erythromycin, clarithromycin, and telithromycin -- HIV protease inhibitors (such as indinavir, nelfinavir, ritonavir,

Antiretroviral Therapy for HIV: New Data From HIV 8 in Glasgow  -  26 Dec 2006
Medscape (subscription)However, the MaxCmin 1 study with saquinavir/r vs indinavir/r was one of the first of these trials and found that saquinavir/r outperformed indinavir/r,

PRESIDENT’S ADDRESS TO THE MEMBERS OF BOTH HOUSES OF PARLIAMENT ON ...  -  Dec 1, 2006
Press Information Bureau (press release),Another medicine found is INDINAVIR with equally good results. A foreign University has tried a combination of AZT-INDINAVIR and 3TC, for some patients,

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

Merck Gets Punk'd by Thailand  -  Dec 16, 2006
Motley FoolIn 2004, global combined sales of Crixivan (indinavir)/Stocrin (Efavirenz) reached $256 million. Thailand's Health Ministry has argued that it cannot afford

Study of Dasatinib or 800 Mg of Imatinib Mesylate Shows Patients ...  -  Dec 14, 2006
DG News...ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, atazanavir, indinavir, nefazodone, nelfinavir, saquinavir, and telithromycin).

Combined Regimen of Darunavir and Ritonavir Produces Significant ...  -  Dec 14, 2006
DG News...darunavir and ritonavir 600/100 mg twice daily plus an optimized background regimen without PI combinations except for atazanavir and indinavir.

Dr Hadwen Trust: Weatherall primate research report published today  -  Dec 13, 2006
Politics.co.uk,Methoxyflurane (anaesthetic; caused kidney failure in humans); Indinavir (anti-AIDS drug; metabolic differences); Flosint (arthritis; lethal for humans);

Local version of new Aids drug planned  -  Nov 28, 2006
Bangkok Post,Other anti-Aids drugs the GPO expects to produce in the next two years include Indinavir, Saquinavir, ddI and Lopinavir, the GPO chief added.

Thailand to issue compulsory license for efavirenz  -  Nov 29, 2006
Aidsmap,GPO Director Mongkol Jivasantikarn told the Bangkok Post that the organisation plans to manufacture indinavir, saquinavir, lopinavir and ddI in the next two

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),...or fenofibrate) -- the antibiotics erythromycin, clarithromycin, and telithromycin -- HIV protease inhibitors (such as indinavir, nelfinavir, ritonavir,

Antiretroviral Drug Resistance in Patients With HIV  Nov 6, 2006
...for other PIs are 1.2 FC/5.4 FC for tipranavir/r (TPV/r), 9.7 FC/56.1 FC for LPV/r, 7.1 FC/26.5 FC for saquinavir/r, and 10.6 FC/40.1 FC for indinavir/r (Table ... -Medscape (subscription) Published Data Showed Vardenafil Treated Erectile Dysfunction ...  Nov 3, 2006
In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended, and ... -DG News my private weblog  Oct 31, 2006
These include quinidine, procainamide, amiodarone 2006 inurl levitra march p sotalol.ritonavir (Norvir®) or indinavir sulfate (Crixivan®)ketoconazole or ... -Digital Divide Network, New risk factors for severe liver toxicity identified in largest ...  Nov 3, 2006
...reverse transcriptase inhibitor (NNRTI), either nevirapine or delavirdine; or two NRTIs and a single, unboosted, protease inhibitor, indinavir (Crixivan). ... -Aidsmap, Merck buys protease inhibitor from Ambrilia, may be potent booster ...  Oct 20, 2006
No cross-resistance to amprenavir, lopinavir, atazanavir, saquinavir, indinavir, and nelfinavir was observed for any viral mutants, but resistance mutations ... -Aidsmap, Quantitative magnetic resonance and SPECT imaging for macrophage ...  Oct 30, 2006
Toward this end, BM macrophages (BMM) were used as carriers for nanoparticle-formulated indinavir (NP-IDV), and the cell distribution was monitored by single ... -Journal of Leukocyte Biology (subscription) Brain-protecting medicines for HIV a research priority  Oct 17, 2006
A few of today’s HIV-suppressing drugs, such as nevirapine, abacavir, AZT and indinavir, can penetrate the blood-brain barrier. ... -Wilkes Barre Times-Leader, Aptivus®(tipranavir) Demonstrates Durable Response Through Nearly ...  Oct 15, 2006
...comparator protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r (Crixivan®). ... -Medical News Today (press release), Scientists battle HIV dementia  Oct 16, 2006
A few of today's HIV-suppressing drugs, such as nevirapine, abacavir, AZT and indinavir, can penetrate the blood-brain barrier, says Dr. Ron Ellis of the ... -Indianapolis Star, Full Text  Oct 12, 2006
...well with experiment for the structural rearrangement of the enzyme chorismate mutase; the method has also been applied to the antiretroviral drug indinavir. ... -Science Magazine (subscription) AIDS drug prices to fall  24 Sep 2006
HAL and RDPL will launch six anti-retrovirals which are off-patented — Lamivudine, Indinavir, Nevirapine, Lidovudine, Didanosine, and a combination of ... -Times of India

AIDS drug prices to fall by 32%  24 Sep 2006
Drugs such as Nevirapine, Lamivudine, Didanosine, Indinavir would come at prices that are 7% to 32% less than supplied by private companies. ... -Financial Express

Kaiser Daily HIV/AIDS Report Highlights Recently Released Journal ...  Sep 19, 2006
Among the participants, 56 were treated with protease inhibitors -- indinavir, nelfinavir, ritonavir or saquinavir -- and 54 were treated with non-nucleoside ... -Medical News Today

Central package wipes HA slate clean but leaves little for ...  Aug 30, 2006
...used to treat HIV. He said the HA would now manufacture indinavir sulfate 400, zidovudine 300 and lamivudine 300. He said the Centre ... -Expressindia.com

- Study of Chronic-Phase Patients with Chronic Myelogenous ...  -  Dec 11, 2006
PR Newswire (press release),...ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, atazanavir, indinavir, nefazodone, nelfinavir, saquinavir, and telithromycin).

Atazanavir Urolithiasis  -  Nov 15, 2006
New England Journal of Medicine (subscription),1 Among the antiretroviral agents that are currently in use, only indinavir is known to cause kidney stones. 2 We describe a patient who had hydronephrosis

PRESIDENT’S ADDRESS TO THE MEMBERS OF BOTH HOUSES OF PARLIAMENT ON ...  -  Dec 1, 2006
Press Information Bureau (press release),Another medicine found is INDINAVIR with equally good results. A foreign University has tried a combination of AZT-INDINAVIR and 3TC, for some patients,

Long-Term Data Show Aptivus(R) (tipranavir) Continues to ...  -  Nov 15, 2006
Drug Newswire (press release),...greater improvements in health-related quality of life (HRQOL) in comparison to treatment with lopinavir/r, amprenavir/r, saquinavir/r or indinavir/r.

Drug-Drug Interactions Clinically Manageable With PREZISTA(TM)  -  Nov 14, 2006
Drug Newswire (press release),Some co-administered drugs, such as indinavir, sildenafil and atorvastatin may require dose adjustments. In general, the study found that drug interactions

Thailand to issue compulsory license for efavirenz  -  Nov 29, 2006
Aidsmap,GPO Director Mongkol Jivasantikarn told the Bangkok Post that the organisation plans to manufacture indinavir, saquinavir, lopinavir and ddI in the next two

Local version of new Aids drug planned  -  Nov 28, 2006
Bangkok Post,Other anti-Aids drugs the GPO expects to produce in the next two years include Indinavir, Saquinavir, ddI and Lopinavir, the GPO chief added.

24-week Results From Aptivus® (tipranavir) RESIST Studies ...  -  Nov 22, 2006
Medical News Today (press release),...comparator protease inhibitors that include lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®), and indinavir/r (Crixivan®).

Long-Term Data Show Aptivus(R) (tipranavir) Continues to ...  -  Nov 14, 2006
Earthtimes.org...or greater improvementsin health-related quality of life (HRQOL) in comparison to treatment withlopinavir/r, amprenavir/r, saquinavir/r or indinavir/r.

NRTI-sparing combination of ritonavir-boosted indinavir and ...  Aug 9, 2006
NRTIs) show modest improvements in fat loss from under the skin after switching to a combination of ritonavir (Norvir)-boosted indinavir (Crixivan) and ... -Aidsmap

Large analysis shows benefits of starting treatment with efavirenz  Aug 22, 2006
The boosted protease inhibitors included were amprenavir (Agenerase), lopinavir (Kaletra), saquinavir (Invirase / Fortovase) and indinavir (Crixivan): newer ... -Aidsmap

Marijuana Use Does Not Accelerate HIV Infection  Aug 19, 2006
...metabolism. Although marijuana use did produce a drop in indinavir levels, this fall was small and unlikely to be clinically meaningful. ... -Online - International News Network

Lowered AZT dose for low weight patients 'effective and reduces ...  Aug 9, 2006
...a first-line potent antiretroviral therapy regimen that consisted of zidovudine 200mg, lamivudine (3TC) 150mg, and ritonavir-boosted indinavir (Crixivan) 600mg ... -Aidsmap

Cause of ALS yet unknown; cure is far off  Aug 20, 2006
...in treating ALS, including the antibiotic minocycline (Minocin), the breast-cancer drug tamoxifen (Nolvadex), the HIV/AIDS drug indinavir (Crixivan), the COX-2 ... -Fort Wayne Journal Gazette

World looking to Brazil for answers  Aug 5, 2006
...and Merck & Co. to lower prices for efavirenz and indinavir by 60 per cent, a saving of $43 million a year. Last year, Brazil again ... -Toronto Star

The Lancet Publishes 48-week Results From Tipranavir RESIST ...  Aug 8, 2006
...comparator protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r (Crixivan ... -DG News

Nevirapine-based triple-drug combinations safe for use in pregnant ...  Jul 10, 2006
Only ten of the 46 women with severe toxicity needed to change treatment, replacing nevirapine with either nelfinavir (Viracept) or indinavir (Crixivan). ... -Aidsmap

HIV - Updated Information On Aptivus® (tipranavir) Clinical Trial ...  Jul 9, 2006
...response based on resistance testing. The comparator PIs were lopinavir, indinavir, saquinavir and amprenavir. Patients in the RESIST ... -Medical News Today

Clinical Pharmacology of Antiretroviral Therapy -- New Data for ...  Jun 22, 2006
Indeed, indinavir (Crixivan, Merck), and to a lesser extent lopinavir, clearance was influenced by orosomucoid concentration and phenotype. ... -Medscape (subscription)

FDA Approves Sprycel (Dasatinib) With Two Indications  Jun 29, 2006
...concentrations are: CYP3A4 inhibitors (eg, ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, atazanavir, indinavir, nefazodone, nelfinavir ... -DG News



Starting treatment with Kaletra involves greater risk of increased ...  Apr 24, 2006
...taking efavirenz having a 60% reduction in risk compared to Kaletra, with a 70% reduction in risk compared to Kaletra seen for both indinavir and nelfinavir. ... - Aidsmap

Astellas Launches VAPRISOL(R) for the Treatment of Euvolemic ...  Apr 26, 2006
The co-administration of VAPRISOL with potent CYP3A4 inhibitors, such as ketoconazole, itraconazole, clarithromycin, ritonavir, and indinavir, is also ... - Yahoo! News





60 or 70 - Remain Sexually Fit  Apr 10, 2006
...macrolide antibiotics such as clarithromycin or erythromycin; medicine for high blood pressure; or Protease inhibitors such as ritonavir or indinavir. ... - LiveArticles.org

Evolution des résistances VIH-1 au traitement  Apr 5, 2006
Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy. N Engl J Med. ... - Warning.info

Marijuana Use Does Not Accelerate HIV Infection  Mar 31, 2006
...metabolism. Although marijuana use did produce a drop in indinavir levels, this fall was small and unlikely to be clinically meaningful. ... - PakTribune.com

Study finds no link between brain-penetrating antiretroviral drugs ...  Mar 21, 2006
...zidovudine, Retrovir), d4T (stavudine, Zerit), 3TC (lamivudine, Epivir), abacavir (Ziagen), nevirapine (Viramune), efavirenz (Sustiva) and indinavir (Crixivan ... - Aidsmap

Study Shows Levitra Treats Erectile Dysfunction Effectively in Men ...  Mar 22, 2006
In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended, and ... - DG News

Merck Sharp and Dohme (MSD) Again Reduces Price of STOCRIN ...  Mar 16, 2006
...countries were being treated with antiretroviral regimens containing either of MSD's two current HIV/AIDS medicines, STOCRIN and CRIXIVAN (indinavir sulfate). ... - AllAfrica.com

US firm reduces price of ARVs  Mar 7, 2006
...were being treated with antiretroviral regimens containing either of MSDís two current HIV and AIDS medicines, STOCRIN and CRIXIVAN (indinavir sulfate). ... - The Swazi Observer



CROI: Low rates of resistance seen in Staccato trial of CD4-guided ...  Feb 26, 2006
...resistant virus contained two mutations in the protease gene (M36I and M46I), which would result in resistance to the protease inhibitor indinavir (Crixivan). ... - Aidsmap,

Gilead Sciences Welcomes Guidance From Nice On Treatment Of ...  Feb 22, 2006
At doses of adefovir dipivoxil from 60 mg to 120 mg, no interactions with zidovudine, nelfinavir, nevirapine, indinavir, efavirenz, delaviridine, or lamivudine ... - Medical News Today,

Multi-component drug delivery system: An emerging trend  Feb 8, 2006
Protease Inhibitors (PIs), which include amprenavir (Agenerase), nelfinavir (Viracept), saquinavir (Fortavase), indinavir (Crixivan), ritonavir (Norvir ... - Express Pharma Pulse,

Boehringer Ingelheim Announces 48-week Results from Aptivus(R) ...  09 Feb 2006
CPIs included lopinavir, saquinavir, amprenavir and indinavir. ... The comparator PIs were lopinavir, indinavir, saquinavir and amprenavir. ... - PR Newswire

Multi-component drug delivery system: An emerging trend  Feb 8, 2006
Protease Inhibitors (PIs), which include amprenavir (Agenerase), nelfinavir (Viracept), saquinavir (Fortavase), indinavir (Crixivan), ritonavir (Norvir ... - Express Pharma Pulse

Advances in First-Line and "Switch" Antiretroviral Strategies for ...  Feb 2, 2006
A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic ... - Medscape (subscription)

Reduce platelet aggregation, blood clotting, inflammation, nervous ...  Jan 12, 2006
It cannot be used together with the anti-Aids drug indinavir, or cyclosporine, used to treat some auto immune disease like systemic lupus erythematosis and to ... - Health24.com


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