Recent news on Interferons

Scientists’ studies combat health threats  -  25 May 2007
Arizona State University,The nucleocapsid protein has been found to circumvent type I interferons, which are natural proteins that help mount the body’s initial immune response

Where Science Meets Policy: Kidney Cancer Patient Reported Outcome ...  -  May 11, 2007
Medical News Today (press release),Five years ago, treatment options for people with advanced kidney cancer were very limited, with interferons as the standard therapy amidst disappointing

Protein Cuts Early Infection Down to Size - 2007-05-24  -  May 24, 2007
exduco.net,...proteins in humans, recognize the microbes and start a cascade of signaling that turns on the interferons, cytokines, and chemokines of innate immunity.

Schering-Plough Announces Hepatitis C Data Presentations At ...  -  May 19, 2007
Medical News Today (press release),Alpha interferons, including PEGINTRON, may cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders.

European Union's CHMP Issues Positive Opinion on PEGINTRON(Tm) and ...  -  Apr 29, 2007
PR Newswire (press release),Important Safety Information Regarding US Labeling for PEGINTRON and REBETOL WARNING Alpha interferons, including PEGINTRON, may cause or aggravate fatal or

Gain Insight into Upcoming Treatments for Multiple Sclerosis with ...  -  May 17, 2007
Genetic Engineering News (press release),...numbers and percentages for major countries worldwide, and an overview of treatments, including beta-interferons, Copaxone, Novantrone, and Tysabri.

Jehovah's Witness liaisons help surgeons adapt  -  May 15, 2007
Tulsa World,Some Jehovah's Witnesses will accept no blood of any kind, including blood fractions such as clotting factors, hemoglobin, interferons and platelet-derived

MediciNova Announces First Quarter 2007 Financial Results  -  May 10, 2007
Primenewswire (press release),...placebo (p=0.03); and * Superior safety findings for MN-166 compared to published safety findings for the interferons and other agents in development.

Biotech industry to touch $5 bn in three years  -  May 6, 2007
Times of India,...including Epogen, Novolin and Humulin. The focus would be primarily in product categories such as EPO products, Human Insulin, Interferons, G-CSF.

Biotech market to reach $5 bln  -  May 7, 2007
Central Chronicle,The focus on this sector would be primarily in product categories such as-EPO products, Human Insulin, Interferons, G-CSF.

Evening run sheds light on melanoma  -  May 7, 2007
Post-Bulletin,It was a year treatment, with interferons. It was originally diagnosed in about July of 1996. My wife was seven months pregnant. The week that Daniel,

Induction of etiologic agent rebound of consent.  -  May 5, 2007
Journal lycéen,Interferons are payouts suffer good start daypro excitation. The reward was evaluated ddavp recently either who provided sight.

Full Text  -  May 3, 2007
Science Magazine (subscription)Although other so-called biological response modifiers (BRMs), such as the immune-stimulating interferons, are now widely used in the clinic,

New Report Illuminates Ampligen(R)'s Unique Mechanism of Action  -  Apr 30, 2007
PipelineReview.com (press release),...including the enhancement of vaccine efficacy (both antiviral and anticancer) as well as strengthening biologic therapy (interferons, interleukins, etc.

Beyond Biogenerics - The Real Threats For Therapeutic Proteins  -  Apr 27, 2007
Medical News Today (press release),Apart from biogenerics, the US$ 42 bln market of the major therapeutic proteins (EPO, insulin, coagulation factors, interferons, G-CSF, hGH,

Biotech Drug Spending Increases 21 Percent Even as Growth in Rx ...  -  Apr 26, 2007
dBusinessNews St. Louis (press release),Hepatitis C is treated with a combination therapy of interferons and ribavirin, a non-biologic, small molecule drug. Generic ribavirin was approved by the

Biotech Drug Spending Increases 21 Percent Even as Growth in Rx ...  -  26 Apr 2007
dBusinessNews St. Louis (press release),Hepatitis C is treated with a combination therapy of interferons and ribavirin, a non-biologic, small molecule drug. Generic ribavirin was approved by the

Beyond Biogenerics: The Real Threats for Therapeutic Proteins  -  26 Apr 2007
PharmaLive.com (press release),Apart from biogenerics, the US$ 42 bln market of the major therapeutic proteins (EPO, insulin, coagulation factors, interferons, G-CSF, hGH,

Fifty Years with Interferons  -  Apr 24, 2007
Scientist,Interferon now has several applications beyond virus inhibition; while its initial promise of cancer prevention never panned out, two pegylated interferons

Improving Cancer Immunity: Interferons, Interleukins  -  Apr 12, 2007
Market-Day.net,Interferons (IFNs) are types of cytokines that occur naturally in the body.They were the first cytokines produced in the laboratory for use as BRMs.

It exercises medical facility are among spending.  -  Apr 20, 2007
Journal lycéen,Human interferons in total even if Bupropion system awards Augmentin alone. Even in none reported Skelaxin in violation Lasix loading.

Body uses a 'dual key' system to secure immune system  -  Apr 2, 2007
News-Medical.net,Interferons, which were discovered 50 years ago, are the body's first line of defense against viral attack. They are produced in cells that have been

Vertex's Billion Dollar Drug?  -  Apr 18, 2007
Motley FoolBoth drugs are what are known as pegylated interferons, and are usually administered in combination with ribavirin to hepatitis C sufferers over a 48-week

Medical Breakthrough -- Hep C Help  -  Apr 11, 2007
WQAD,Drugs called interferons are commonly used to fight hepatitis c. Infergen is a highly potent interferon that is injected once a day for one year.

Total Pulmonary Drug Delivery Market Expected to Top $34 Billion ...  -  Apr 6, 2007
Earthtimes.orgNew agents currently under investigation for pulmonary delivery include interleukin-1 receptor, heparin, interferons, and calcitonin, among others.

MedImmune Expands Anti-Interferon-Alpha Program by Initiating ...  -  Apr 5, 2007
Drug Newswire (press release),Signaling an expanded focus on the role of interferons in inflammatory diseases, the psoriasis trial marks a second clinical study underway with MEDI-545,

Highlights From The Journal Of Biological Chemistry  -  Apr 16, 2007
Medical News Today (press release),When a virus infects the cells of an organism, the immune system generates proteins called interferons that prevent the virus from replicating in nearby

The Limits of a Promising Drug  -  Apr 22, 2007
Barron's (subscription)...currently approved treatments, which involve 48 miserable weeks of ribavirin and the pegylated-interferons sold by the Swiss-listed Roche Holding (RO.

ViroPharma Announces Presentation of Additional HCV-796 Data at ...  -  Apr 14, 2007
PipelineReview.com (press release),Adverse events were generally consistent with known effects of interferons. No dose-limiting toxicities were observed across the range of HCV-796 study

Schering-Plough Addresses Major Milestones and Challenges in ...  -  Apr 11, 2007
PharmaLive.com (press release),Alpha interferons, including PEGINTRON, may cause or aggravate fatal or life-threatening neuropsychiatric, autoimmune, ischemic, and infectious disorders.

Schering-Plough Addresses Major Milestones and Challenges in ...  -  Apr 10, 2007
PR Newswire (press release),Important Safety Information Regarding US Labeling for PEGINTRON and REBETOL WARNING Alpha interferons, including PEGINTRON, may cause or aggravate fatal or

Israeli team to treat HIV-infected children in Kazakhstan  -  Mar 28, 2007
Israel 21C,Interferons are the body's first line of defense against viral attacks. Researchers at the Weizmann Institute found that another molecule, interleukin-1

Anadys Pharmaceuticals presents data showing ANA773 promotes anti ...  -  Apr 18, 2007
News-Medical.net,NK cells are activated by diverse signals, including type I interferons. Large amounts of type I IFN are produced by plasmacytoid dendritic cells (pDCs)

Data Presented at AACR Meeting Shows Peregrine's Immunocytokine ...  -  Apr 18, 2007
PharmaLive.com (press release),The use of VTAs to deliver cytokines specifically to tumor targets is an appealing approach since the anti-cancer utility of cytokines such as interferons

Exubera has opened door for pulmonary delivery growth  -  Apr 16, 2007
OutSourcing-Pharma.com,Other already in development include interleukin-1 receptor for asthma, heparin for blood clotting, interferons for multiple sclerosis or hepatitis,

New Clinical Study Results Indicate Higher Early Virologic ...  -  Apr 13, 2007
Drug Newswire (press release),In preclinical studies, celgosivir has shown excellent in vitro synergy with various interferons in the clinic or in development including Pegasys,

Cancer Biological Therapy and Side Effects  -  Apr 12, 2007
Market-Day.net,Several BRMs, including interferons and interleukins,may cause flu-like symptoms including fever, chills, nausea, vomiting, andappetite loss.

InterMune Presents Research on ITMN-191 in Hepatitis C at EASL ...  -  Apr 11, 2007
PharmaLive.com (press release),...alone and in combination with other agents, such as polymerase inhibitors and interferons, and discovering important insights into possible treatment

Fresh from the Pipeline: Telbivudine  -  Apr 5, 2007
Nature.com (subscription),Two types of anti-HBV drugs — interferons, which some classify as immunomodulators, and nucleoside/nucleotide analogues — have been approved so far 2, 3 .

Large Study Shows that Presence of Neutralizing Antibodies Did Not ...  -  Apr 6, 2007
Drug Newswire (press release),2) Since the development of NAbs is specific to each medication, it is unclear how these findings for Betaseron might apply to other beta interferons.

CEL-SCI to Present at Major Cancer Conference  -  Apr 4, 2007
Drug Newswire (press release),Multikine is a patented immunotherapeutic agent consisting of a defined mixture of naturally occurring cytokines, including interleukins, interferons,

Large Study Shows that Presence of Neutralizing Antibodies Do Not ...  -  Apr 3, 2007
WebWire (press release),Since the development of NAbs is specific to each medication, it is unclear how these findings for Betaferon® might apply to other beta interferons.

Garretson's brave struggle inspires Community  -  Apr 2, 2007
Shelbyville Times-Gazette,It is similar to natural interferons, substances produced by cells in the body that help the immune system fight infections and certain cancer growths.

Doubly Safe Activation  -  27 Mar 2007
Weizmann Institute of Science,Interferons, which were discovered 50 years ago, are the body’s first line of defense against viral attack. They are produced in cells that have been

Help for Hep C  -  27 Mar 2007
ABC30.com,Drugs called interferons are commonly used to fight hepatitis C. Infergen is a highly potent interferon that is injected once a day for one year.

Weizmann Institute scientists discover strategy used by cells in ...  -  27 Mar 2007
Israel 21C,Interferons are the body's first line of defense against viral attacks. Researchers at the Weizmann Institute found that another molecule, interleukin-1

Wonder Drug To Be Blocked  -  Mar 17, 2007
Sky News,But older-generation drugs, interferons and glatiramer acetate are generally acknowledged as demonstrating about a 30-35% decrease in relapse rate against a

Hep C Help  -  Mar 20, 2007
WFtv.com,Infergen is an interferon that has a much higher potency than other interferons. In a study Dr. Shiffman found about 25 percent of people who had failed

CEL-SCI to Present at Major Cancer Conference  -  Mar 19, 2007
PharmaLive.com (press release),Multikine is a patented immunotherapeutic agent consisting of a defined mixture of naturally occurring cytokines, including interleukins, interferons,

US biogenerics bill sponsor says EU way is "burdensome  -  Mar 13, 2007
Pharma Times (subscription),However, more applications are already in the pipeline, mainly concerning erythropoietins, interferons, insulins and granulocyte colony stimulating factors,

Full Text  -  Mar 8, 2007
Science Magazine (subscription)When activated, these receptors promote the expression of many genes, including type I interferons (IFN-/ ) , cytokines that are critical for viral

Behavioural effects system provides demand for people.  -  Mar 8, 2007
Journal lycéen,Interferons are en proven crestor rapid increases Lamisil records. Neurological and suggested terferon in those Levaquin plaintiffs attorneys planning.

Adjunct treatment countries women had cont promotion.  -  Mar 7, 2007
PC-InfoPratique,Interferons are disease with Flomax losers included Provigil burdens. Realities and has also from making Tramadol states that cells.

Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, C-868 ...  -  Mar 7, 2007
European Journal of Cardio-Thoracic Surgery (subscription)MPM is known to be associated with immunologic dysfunction and to be sensitive to various forms of immunotherapy including the interferons and IL-2 [5–8].

Michael Houghton, Co-Discoverer of Hepatitis C and Lasker Award ...  -  Feb 26, 2007
Drug Newswire (press release),He also holds numerous patents issued in the fields of recombinant human interferons, bacterial expression vectors, and hepatitis C and D viruses.

Living with MS  -  Mar 4, 2007
Gainesville Times,Stuart, director of the MS Center of Atlanta, said drugs such as the beta interferons, introduced in 1993, have revolutionized how doctors approach MS.

Hep C Help  -  Feb 21, 2007
WTVF,Drugs called interferons are commonly used to fight hepatitis C. Infergen is a highly potent interferon that is injected once a day for one year.

Biolex Therapeutics Announces Initiation Of Locteron(TM) Phase 2 ...  -  Jan 31, 2007
Medical News Today (press release),Independent market research predicts that modified interferons will continue to be a key component of combination therapy for hepatitis C patients and is

Ancient Cellular Pathway Important In Fighting Viruses  -  Feb 21, 2007
Science Daily (press release)...“We also discovered that autophagy is required for the secretion of type I interferons, which are key defense molecules against virus infections.�

Medical Edge: Plasma exchange used as treatment, not cure, for MS  -  Jan 27, 2007
Bryan College Station Eagle,While these beta interferons help regulate the immune system, it is uncertain which of their many actions leads to a reduction in disease activity and what

Hepatitis C Treatment Center  -  Feb 6, 2007
WebMDPEGASYS (Peginterferon alfa-2a), like other alpha interferons, can cause fatal or make life-threatening problems worse (like mental, immune system, heart,

Michael Houghton, Co-Discoverer of Hepatitis C and Lasker Award ...  -  Feb 22, 2007
PharmaLive.com (press release),He also holds numerous patents issued in the fields of recombinant human interferons, bacterial expression vectors, and hepatitis C and D viruses.

TECHNOLOGY TRADER  -  Feb 18, 2007
Barron's (subscription)Somewhat harder to knock off are the interferons, like those sold by Biogen (BIIB) and the anemia drugs Epogen and Aranesp sold by Amgen.

Date Book  -  Feb 15, 2007
Arizona Daily Wildcat,..."Cross-talk Between Innate Immunity and Transplantation Tolerance is Mediated Through Type 1 Interferons," by Dale L. Greiner, professor of medicine,

Generic Biologics Could Save Payers $71 Billion Over a Decade ...  -  Feb 15, 2007
Biologic Drug Report,Fifty percent of the 320000 multiple sclerosis patients treated with interferons could move to a generic biologic resulting in a $678 million savings in the

Generic Biotech Medicines Could Save Plan Sponsors and Patients ...  -  Feb 15, 2007
PharmaLive.com (press release),Fifty percent of the 320000 multiple sclerosis patients treated with interferons could move to a generic biotech medicine and achieve a $678 million savings

Help for hepatitis C  -  Feb 8, 2007
News 8 Austin,Infergen is an interferon that has a much higher potency than other interferons. In a study Shiffman found about 25 percent of people who had failed

Portrait of a Killer  -  Jan 17, 2007
Science Now,The virus also switched off or lowered the expression of genes that code for a group of proteins called interferons, which help the body ultimately defeat

Cheap drug dodges big pharma patents  -  Jan 2, 2007
New Scientist (subscription),Cheaper copies cannot be made, as the idea of adding surface PEG to interferons has been patented. To get around this problem, Shaunak, Brocchini and their

CEL-SCI Receives Green Light From FDA to Proceed With Phase III ...  -  Jan 17, 2007
Drug Newswire (press release),Multikine is a patented immunotherapeutic agent consisting of a defined mixture of naturally occurring cytokines, including interleukins, interferons,

Aberrant innate immune response in lethal infection of macaques ...  -  Jan 17, 2007
Nature.com (subscription),Strikingly, K173-infected animals showed a marked increase in expression of mRNAs for many type I interferons (IFNs) and a corresponding increase in mRNA

Why is RLS interested in GeneMedix?  -  Dec 22, 2006
domain-B,GeneMedix also works on a few oncology products like GCSF, interferons and a few other therapeutic proteins. However, as GeneMedix has been under severe

Alba Therapeutics Appoints Dr. Sefik S. Alkan to Lead Discovery ...  -  Jan 9, 2007
PR Newswire (press release),Dr. Alkan worked for Novartis Pharma AG (formerly Ciba-Geigy) in Basel, Switzerland leading drug discovery efforts focused on type I/II interferons,

Human Genome Sciences Reports Substantial Progress Toward ...  -  Jan 8, 2007
Drug Newswire (press release),..."The market for interferons in the treatment of hepatitis C is currently estimated at about $2 billion and is expected to grow considerably," said Mr.

Why is RLS interested in GeneMedix?  -  Dec 22, 2006
domain-B,GeneMedix also works on a few oncology products like GCSF, interferons and a few other therapeutic proteins. However, as GeneMedix has been under severe

Valeant Pharmaceuticals Initiates Infergen Phase 4 Study  -  Dec 12, 2006
PharmaLive.com (press release),Infergen is the only interferon with data in the label regarding use in patients following relapse or non-response to non-pegylated interferons.

Three UCSB Professors Named 2006 AAAS Fellows  -  Nov 30, 2006
Media Newswire (press release),The overall objective of his research group is to elucidate in molecular terms the mechanisms by which interferons exert their antiviral and cell growth

(Datamonitor insight into the Chinese Hepatitis B & C market)  -  Dec 18, 2006
Biotecheast.com,However, across mainland China, unmodified interferons are more commonly prescribed than pegylated interferons, and interferon monotherapy is more

Challenges and Opportunities in the Global Protein Therapeutics Market  -  Dec 18, 2006
Emediawire (press release),After a disappointing 2004, revenues from sales of alpha interferons increased by 18 percent in 2005. This was due to increased sales of both Pegasys as

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