Recent news on Interleukin-2

Inovio's electroporation tech delivers the goods in trial  -  25 May 2007
BiopharmaReporter.com,...in collaboration with RMR and the H Lee Moffitt Cancer Center and Research Institute; interleukin-2 delivered directly to malignant melanomas (with

New Diet & Special Stem Cell Program Proves Successful in Killing ...  -  May 10, 2007
Fuerteventura Digital,In experiments that led up to this new program, a 72 year old gentleman with prostate cancer that spread to his bones was given interleukin 2 & gamma

AVAX Technologies to Present at the Acumen Biofin 4th Annual ...  -  May 14, 2007
PharmaLive.com (press release),DNP modified tumor cells, using techniques similar to M-Vax, followed by administration of low dose interleukin-2, a response rate of 35% was observed.

2007 Gladstone Distinguished Lecturer: Thomas A. Waldmann, MD  -  26 Apr 2007
Synapse,A major area of his efforts is the critical role of the receptor for interleukin-2 (IL-2) on the growth, differentiation and regulation of normal and

Data Presented at AACR Meeting Shows Peregrine's Immunocytokine ...  -  Apr 18, 2007
PharmaLive.com (press release),In these proof of principle studies, VTA immunocytokines were created by combining type I interferon and interleukin 2 with 2aG4, an anti-phospholipid

Retrospective Review In Patients With Pulmonary Metastases Of ...  -  Apr 16, 2007
Medical News Today (press release),One of the greatest impediments to the delivery of systemic immunotherapy to patients with RCC, particularly interleukin 2 (IL-2), has been the significant

Peregrine Pharmaceuticals Highlights Significant Advances In The ...  -  Apr 21, 2007
Medical News Today (press release),These are combinations of vascular targeting agents such as bavituximab and immune system-stimulating cytokines such as interferon and interleukin-2.

Peregrine's (PPHM) Immunocytokine Fusion Proteins Reduce Growth of ...  -  Apr 18, 2007
StreetInsider.com (subscription),...(AACR) showed that fusion proteins combining the anti-cancer cytokines alpha interferon and interleukin 2 (IL-2) with 2aG4, a bavituximab equivalent,

Dream Genes  -  Apr 17, 2007
Walrus Magazine,This illness occurs when the body fails to produce a protein called interleukin-2, a critical component of the body’s immune-response system.

Transgene and Roche Enter Partnership on Therapeutic Vaccines ...  -  Apr 11, 2007
CNW Telbec (Communiqués de presse),...the HPV16 E6 and E7 antigens) and to further stimulate the infection-clearing activity of the immune system through an adjuvant (interleukin 2).

Transgene, Roche Enter Potential $293M Alliance On HPV Vaccine  -  Apr 11, 2007
BioWorld Online,...and to further stimulate the infection-clearing activity of the immune system through an interleukin-2 adjuvant, Transgene said.

Improving Cancer Immunity: Interferons, Interleukins  -  Apr 12, 2007
Market-Day.net,Many interleukins have beenidentified; interleukin-2 (IL-2 or aldesleukin) has been the most widelystudied in cancer treatment. IL-2 stimulates the growth

Market Report -- In Play (PPHM)  -  Apr 18, 2007
MSN Money...and interleukin 2 with 2aG4, a bavituximab equivalent, demonstrated potent anti-cancer activity in preclinical models of B-cell lymphoma and melanoma.

Mymetics' HIV Vaccine Achieves Research Breakthrough, Eliciting ...  -  Mar 31, 2007
Medical News Today (press release),...though subtle three-dimensional mimicry between the viral envelope glycoprotein gp41 and the IL-2 cytokine (Interleukin-2) of the infected host.

Cerimon Pharmaceuticals Initiates ARREST UC-1, a Global Phase 2b ...  -  Apr 5, 2007
Drug Newswire (press release),Basiliximab is a monoclonal antibody that selectively blocks the interleukin-2 (IL-2) receptor. Cerimon believes basiliximab's highly targeted inhibition of

New vaccine aims to slow down progression of kidney cancer  -  Apr 9, 2007
SpiritIndia,...working in concert with standard treatment (low dose Interleukin 2, Interferon Alpha, or Sunitinib) for kidney cancer, can prolong the lives of these

Wyeth kidney cancer drug nears approval from FDA  -  Apr 5, 2007
NorthJersey.com,Before last year, physicians treated kidney cancer with interferon and interleukin-2, medicines that spurred an immune system attack on tumor cells.

Immunotherapy Does Not Prolong Life When Skin Cancer Spreads  -  Mar 20, 2007
Science Daily (press release)The review examined two kinds of immunotherapy combined with chemotherapy, interferon and interleukin-2. Of the 11 studies that reported on side effects

Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, C-868 ...  -  Mar 7, 2007
European Journal of Cardio-Thoracic Surgery (subscription)A phase II study of combined intravenous and subcutaneous interleukin-2 in malignant pleural mesothelioma. Lung Cancer 2001;31:67-72.[CrossRef][Medline]

Immunotherapy does not prolong life in malignant melanoma  -  Mar 7, 2007
HealthandAge.comThe immunotherapies used were interferon and interleukin-2 and both were associated with serious side effects. Interleukin-2, which has to be administered

Zinc supplementation decreases incidence of infections in the ...  -  Mar 7, 2007
Am J Clin Nutr (subscription),Plasma zinc and phytohemagglutin-induced interleukin 2 mRNA in isolated mononuclear cells were significantly higher in the zinc-supplemented than in the

StreetInsider.com Unusual 11 Mid-Day Movers 02/28/2007  -  Feb 28, 2007
StreetInsider.com (subscription),...its lead oncology product candidate that is administered in conjunction with low dose interleukin-2 (IL- 2) and is intended for use in the maintenance

Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, C-868 ...  -  Mar 7, 2007
European Journal of Cardio-Thoracic Surgery (subscription)...pleurectomy/decortication (P/D), adjuvant radiation (30 Gy), and systemic chemotherapy followed by long-term subcutaneous interleukin-2 (IL-2).

Synbiotic Preparation Reduces Colon Cancer Risk Factors  -  Feb 20, 2007
Cancerpage.com,The synbiotic preparation had apparently beneficial effects on levels of interleukin-2 and interferon gamma, the report indicates.

Dietary synbiotics reduce cancer risk factors in polypectomized ...  -  Feb 6, 2007
Am J Clin Nutr (subscription),Synbiotic consumption prevented an increased secretion of interleukin 2 by peripheral blood mononuclear cells in the polypectomized patients and increased

The Future Of Allogeneic Hematopoietic Stem Cell Transplantation ...  -  Feb 5, 2007
Medical News Today (press release),...or prolonged stabilization of disease, but no durable complete responses as those seen with immunotherapy such as interferon, interleukin 2, and BMT.

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,Another cytokine, interleukin-2, which also prevents apoptosis, was used as a positive control. Cells treated with IL-7 showed lower levels of apoptosis.

Founder of Hacienda club reveals he has cancer  -  Feb 14, 2007
Guardian Unlimited,He feels lucky that his form of cancer can be treated by the Interleukin 2 drug and he does not need the more expensive Sutent drug that has not yet been

Mr Manchester: My cancer battle  -  Feb 14, 2007
Manchester Evening News,That afternoon, the Prof returns; good news, my cancer has the markers which say that Interleukin 2 may work so that's what we're going to do.

ProMetic reports positive cancer drug research  -  Jan 30, 2007
Pharmaceutical Business ReviewPBI-1393 is a less toxic and relatively inexpensive drug with proven stimulation effect on human cytotoxic T-lymphocytes (CTLs) comparable to interleukin-2.

Lab research may one day lead to cancer treatment using patient's ...  -  18 Jan 2007
Biology News Net (press release),The T cells are activated with molecular agents called interleukin-2 and anti-CD3 antibody (OKT3). It is hoped that results from this research could lead to

Advanced Kidney Cancer - Median Progression-free Survival Doubled ...  -  Jan 14, 2007
Medical News Today (press release),RCC who have failed prior interferon-alpha or interleukin-2 based therapy and also 1st line when patients are considered unsuitable for such therapy.

Drugs show promise against kidney cancer  -  Jan 10, 2007
CNNInterleukin-2 and interferon alfa are often given to treat it. But they work in only about 5 percent of patients whose tumors have spread.

Vical Initiates Pivotal Phase 3 Trial Of Allovectin-7(R) As First ...  -  Jan 6, 2007
Medical News Today (press release),The toxicity associated with FDA-approved treatments such as dacarbazine or interleukin-2 is often significant, resulting in serious or life-threatening

New developments from EpiCept outlined recently.  -  Jan 4, 2007
Therapeutics Daily (subscription) (press release),...administered in conjunction with interleukin-2 (IL-2), for the maintenance of first remission in patients with acute myeloid leukemia (AML).

Bayer And Onyx Announce Pivotal Nexavar Kidney Cancer Study ...  -  Jan 15, 2007
Medical News Today (press release),...status or risk group, including patients who had not received conventional treatment with biologics, such as interleukin-2 or interferon-alpha.

Bayer and Onyx announce pivotal Nexavar kidney cancer study ...  -  Jan 11, 2007
PressZoom (press release),...status or risk group, including patients who had not received conventional treatment with biologics, such as interleukin-2 or interferon-alpha.

New Biotech Drugs to Aid in Renal Cell Carcinoma Treatment  -  Jan 11, 2007
MedIndia,The standard drugs used are interferon alfa and interleukin-2. Yet these drugs help in only 5 percent of cases where the tumors have spread.

Targeted Drugs Slow Kidney Cancer  -  Jan 10, 2007
WebMDFor many years, the toxic therapies interferon alfa or interleukin-2 have been the only available treatments for advanced renal kidney cancer, but they work

County dedicates Burton Law Library  -  Jan 3, 2007
Weiser Signal American,The medical establishment regarded Burton as one of the most responsive patients ever to treatment with Interleukin-2, a powerful concoction which enlists

Cytokine Storm and an Anti-CD28 Monoclonal Antibody  -  Dec 13, 2006
New England Journal of Medicine (subscription),In our minds, in the setting of severe lymphopenia and monocytopenia of unknown duration, treatment with high-dose corticosteroids and anti–interleukin-2

THE RIGHT TO A TRIAL  -  Dec 9, 2006
New Yorker,Karnes’s doctors treated her with interleukin-2, a protein that stimulates the immune system and, in its synthetic form, was the only medication approved by

EpiCept officials describe the recent activities  -  Dec 7, 2006
Therapeutics Daily (subscription) (press release),...administered in conjunction with interleukin-2 (IL-2), for the maintenance of first remission in patients with acute myeloid leukemia (AML).

Reasons To Consume Goji  -  Nov 30, 2006
FitcommerceInterleukin-2 (IL-2) is a crucial cytokine (cell protein) that induces potent anti-tumor responses in a variety of cancers. Goji polysaccharides have been

T Cell Therapy Helpful in Metastatic Melanoma  -  Nov 29, 2006
Cancerpage.com,Each was accompanied by a 6-day course of low-dose interleukin 2. Overall, 52 infusions were administered. Clinical adverse events, consisting of chills and

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