Recent news on Invirase

Up, up and away  -  May 17, 2007
Newark Star Ledger,Roche's research labs have produced plenty of milestone medicines over the years, from the anxiety drug Valium to Invirase, the first of a powerful group of

GSW Worldwide Named 'Agency of the Year: Category 1' by Med Ad News  -  Apr 18, 2007
Earthtimes.orgIn addition, GSW Worldwide also was nominated for Best Professional Ad for their campaign for Roche's Invirase, and Best Self- Promotion Campaign.

Roche Posts Strong First Quarter Sales – Upgrade of Core Earnings ...  -  Apr 18, 2007
PharmaLive.com (press release),Sales of the HIV medicine Fuzeon increased by 12%, and Invirase/Fortovase by 23%. CellCept sales rose by 7% and remained the top-selling branded

GSW Worldwide Receives Six Nominations at 18th Annual Med Ad News ...  -  Mar 15, 2007
PharmaLive.com (press release),This same group of creative directors also nominated GSW Worldwide for Best Professional Advertisement for a campaign it created for Roche's Invirase,

Asthma drug provides effective treatment for immune reconstitution ...  -  Jan 31, 2007
Aidsmap,Three weeks after initiating a nucleoside-sparing antiretroviral regimen consisting of saquinavir (Invirase) and Kaletra (lopinavir/ritonavir),

Roche Posts Outstanding Results for 2006  -  Feb 7, 2007
PharmaLive.com (press release),Combined sales of Invirase and Fortovase (saquinavir) increased 28% to 182 million Swiss francs. Growth is being fuelled by increasing uptake of the

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,Next came HIV protease inhibitors such as Roche's Invirase/Fortovase (saquinavir), Abbott Laboratories Norvir (ritonavir), Merck & Co's Crixivan (indinavir)

McGuinty Government Improves Access To Drugs  -  Dec 20, 2006
CNW Telbec (Communiqués de presse),Fosavance (Osteoporosis) - Fosamax (Osteoporosis) - Pariet (Acid Suppression) - Invirase (HIV/AIDS) - Sandostatin SC (Oncology and other indications)

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

McGuinty Government Improves Access To Drugs  -  Dec 20, 2006
CNW Telbec (Communiqués de presse),Fosavance (Osteoporosis) - Fosamax (Osteoporosis) - Pariet (Acid Suppression) - Invirase (HIV/AIDS) - Sandostatin SC (Oncology and other indications)

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

NGN Capital's Managing General Partner Georg Nebgen Joins Javelin ...  -  Dec 11, 2006
American Digital Networks (press release),...from F. Hoffmann-La Roche, where he led as Technical Project Leader global research & development team activities for Invirase/Fortovase.

Roche - Initiatives in HIV/AIDS  -  Dec 4, 2006
PharmaLive.com (press release),Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan

Roche Diagnostics Will Mark World AIDS Day  -  Dec 1, 2006
Inside INdiana Business (press release),Roche makes its HIV protease inhibitors – Invirase (saquinavir) and Viracept (nelfinavir) available at no profit prices for direct supplies from Roche Basel

Panacos Announces New Board Member  Oct 27, 2006
Prior to Dupont, Dr. Fischer was Medical Director for Hoffmann-LaRoche's Virology Group, where he was involved in the launch of INVIRASE and developed FORTOVASE ... -PharmaLive.com (press release), ARV drugs may also help fight malaria  Oct 10, 2006
They found that serum taken from people who were taking antiretroviral therapy - which included ritonavir-boosted saquinavir (Invirase) or lopinavir (Kaletra ... -SABC News, The Totally Frightful Issue: Horrific Inspiration  Oct 23, 2006
With long, funny names, they could have been drag queens or, maybe, a punk band: Lexiva, Invirase, Saquinavir, Agenerase, and, of course, who could forget The ... -Queerty, Antiretroviral Drugs: A Shot in the Arm to Fight Malaria?  Oct 12, 2006
...finding revealed that serum taken from people who were undergoing antiretroviral therapy, consisting of ritonavir-boosted saquinavir (Invirase) or lopinavir ... -MedIndia, Aptivus®(tipranavir) Demonstrates Durable Response Through Nearly ...  Oct 15, 2006
...boosted comparator protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r ... -Medical News Today (press release), Chugai to Launch HIV Protease Inhibitor Invirase(R) Tablet 500mg ...  Sep 14, 2006
...announced today the launch of a new drug for HIV (Human Immunodeficiency Virus) infection, HIV Protease inhibitor Invirase® Tablet 500 mg (saquinavir mesilate ... -DG News

Briefs: Roche to help African companies produce drugs to fight HIV  Sep 22, 2006
...in Kenya — with the technical assistance necessary to produce saquinavir, the active ingredient in the Swiss-based pharmaceutical’s Invirase treatment. ... -Lincoln Journal Star

Draft BHIVA treatment guidelines: respond by Monday September 4 th  Aug 30, 2006
Alternative boosted PI regimens recommended by BHIVA include boosted fosamprenavir, boosted saquinavir (Invirase and boosted atazanavir (Reyataz. ... -Aidsmap

Interim Analysis Of New Study Suggests Boosted INVIRASE(R) May ...  -  Nov 14, 2006
Medical News Today (press release),Encouraging results from an interim analysis of a new study suggest that the boosted protease inhibitor (PI/r) INVIRASE(R) 500 mg/r (saquinavir mesylate)

Interim Analysis of New Study Suggests Boosted INVIRASE(R) May ...  -  Nov 13, 2006
PR Newswire (press release),..."These preliminary results suggest that boosted INVIRASE has the power to control the virus in treatment-na??ve patients, while also managing their lipid

New Study Indicates Boosted Invirase 500 Patients Achieve Similar ...  -  Nov 13, 2006
campus med,Notably, the results indicate that Invirase 500/r may have the added benefit of significantly fewer patients developing elevated cholesterol and

New Study Indicates Boosted Invirase 500 Patients Achieve Similar ...  -  Nov 13, 2006
Drug Newswire (press release),Promising head to head results presented today indicate that the boosted protease inhibitor (PI/r) Invirase 500/r appears to achieve similar levels of viral

NGN Capital’s Managing General Partner Georg Nebgen Joins Javelin ...  -  Dec 11, 2006
Business Wire (press release),...from F. Hoffmann-La Roche, where he led as Technical Project Leader global research & development team activities for Invirase/Fortovase.

Roche - Initiatives in HIV/AIDS  -  Dec 4, 2006
PharmaLive.com (press release),Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan

Roche Diagnostics Will Mark World AIDS Day  -  Dec 1, 2006
Inside INdiana Business (press release),Roche makes its HIV protease inhibitors – Invirase (saquinavir) and Viracept (nelfinavir) available at no profit prices for direct supplies from Roche Basel

24-week Results From Aptivus® (tipranavir) RESIST Studies ...  -  Nov 22, 2006
Medical News Today (press release),...comparator protease inhibitors that include lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®), and indinavir/r (Crixivan®).

Long-Term Data Show Aptivus(R) (tipranavir) Continues to ...  -  Nov 15, 2006
Drug Newswire (press release),...protease inhibitors that include lopinavir/r (Kaletra(R)), amprenavir/r (Agenerase(R)), saquinavir/r (Invirase(R)) and indinavir/r (Crixivan(R)).

Boosted saquinavir has similar potency, better lipid profile than ...  -  Nov 14, 2006
Aidsmap,The GEMINI trial, sponsored by Roche, who market saquinavir as Invirase, a 48-week open-label international study of the two drugs in 337 antiretroviral

(PRN) - Tyson Reports Fourth Quarter and Fiscal Year 2006 Results ...  -  Nov 13, 2006
Bolsamania.com,...(PRN) - New Study Indicates Boosted Invirase 500 Patients Achieve Similar Levels of Viral Suppression to Boosted Lopinavir but with a Better Lipid Profile .

Large analysis shows benefits of starting treatment with efavirenz  Aug 22, 2006
The boosted protease inhibitors included were amprenavir (Agenerase), lopinavir (Kaletra), saquinavir (Invirase / Fortovase) and indinavir (Crixivan): newer ... -Aidsmap

AIDS Drugs, Prices Cut 90%, Remain Out of Reach for Neediest  Aug 13, 2006
Roche is in the process of selecting partners in least- developed countries and sub-Saharan Africa to make generic versions of its Invirase medicine. ... -Bloomberg

Double Boosted Saquinavir/Lopinavir Shows Promise for Nucleoside ...  Aug 17, 2006
Abbott. Roche provided Invirase to children both during and after the study, while Abbott provided Kaletra during the study. [Presentation ... -DG News

Staccato study suggests that some CD4-guided treatment ...  Aug 7, 2006
Eighty per cent of the study’s participants were Thai, all of whom took ritonavir (Norvir)-boosted saquinavir (Invirase) along with two nucleoside reverse ... -Aidsmap

WHO issues paediatric HIV treatment guidelines for low-income ...  Aug 8, 2006
...of ddI and abacavir unless abacavir was used in first-line treatment, plus either lopinavir/ritonavir (Kaletra), saquinavir/ritonavir (Invirase) or nelfinavir ... -Aidsmap

The Lancet Publishes 48-week Results From Tipranavir RESIST ...  Aug 8, 2006
...boosted comparator protease inhibitors (PIs) that included lopinavir/r (Kaletra®), amprenavir/r (Agenerase®), saquinavir/r (Invirase®) and indinavir/r ... -DG News

NRTI-sparing combination of ritonavir-boosted indinavir and ...  Aug 9, 2006
...treatment combinations using protease inhibitors that do not cause such serious metabolic changes such as atazanavir (Reyataz) or saquinavir (Invirase) may be ... -Aidsmap

A Quarter Century of Battling HIV/AIDS  Jul 21, 2006
The year 1995 marked the beginning of another era, that of the protease inhibitors, the first of which was Invirase (saquinavir mesylate, SQV) from Roche ... -Drug Discovery & Development

Acid-reducing agent increases saquinavir levels in HIV-negative ...  Jul 10, 2006
The stomach acid-reducing agent omeprazole (Losec) causes an 82% increase in the levels of saquinavir (Invirase) in the blood, when saquinavir is boosted with ... -Aidsmap

Drug company CEO keeps medicine in the family  Jul 12, 2006
Despite leading groundbreaking work with the protease inhibitor Invirase ---- the first AIDS cocktail drug ---- Fischer said he felt stifled by corporate ... -North County Times

Tibotec and J&J Cleared to Launch Aptivus Rival  Jun 29, 2006
The first approved protease inhibitor was Roche's Saquinavir (invirase), which was poorly absorbed by the digestive tract and rapidly metabolized by the liver. ... -International News Service

Clinical Pharmacology of Antiretroviral Therapy -- New Data for ...  Jun 22, 2006
The PIs saquinavir (Invirase, Roche), nelfinavir (Viracept, Agouron Pharmaceuticals), ritonavir (Norvir, Abbott), lopinavir, and atazanavir (Reyataz, Bristol ... -Medscape (subscription)



International Approvals: Invirase and Remicade  May 15, 2006
On March 31, Health Canada approved a 500-mg tablet formulation of saquinavir mesylate (Invirase, made by Hoffmann-La Roche, Ltd) to reduce the pill count from ... - Medscape (subscription)

Roche Women Honored as 2006 TWIN Awardees  Apr 28, 2006
She led the FDA filings for the early AIDS drugs HIVID® (zalcitabine) and Invirase® (saquinavir mesylate), which positively affected the lives of countless ... - Yahoo! News





Wide variability in drug levels casts doubt on the practicality of ...  Mar 28, 2006
...active metabolite M8. ICVs for ritonavir (Norvir) were 34 and 43%, while for saquinavir (Invirase), they were 52 and 55%. The degree ... - Aidsmap

HAART failure rate halves in seven years  Mar 24, 2006
Compared with other single non-boosted protease inhibitors (PIs), regimens containing hard-gel saquinavir (Invirase) tended to be associated with a higher risk ... - Aidsmap



Roche to Focus Resources on Availability of INVIRASE(R), Now ...  Feb 6, 2006
...and distribution of Fortovase(R), the soft-gel formulation of the HIV protease inhibitor saquinavir, due to the continued availability of the INVIRASE(R) 500 ... - International News Service,

Roche To Stop Selling Protease Inhibitor Fortovase Because of ...  Feb 8, 2006
...as saquinavir -- in the US because of decreased demand for the drug and increased demand for a newer formulation of saquinavir, called Invirase, Reuters reports ... - Kaiser network.org,

Roche discontinues marketing of anti-HIV drug Fortovase  Feb 8, 2006
The company also says a newer formulation of the active ingredient in the medication, sold as Invirase, has fewer side effects and a lower pill burden than ... - The Advocate,

CROI: Low rates of resistance seen in Staccato trial of CD4-guided ...  Feb 26, 2006
Overall, 80% of the patients in Staccato took ritonavir (Norvir)-boosted saquinavir (Invirase) along with two nucleoside reverse transcriptase inhibitors (NRTIs ... - Aidsmap,

CROI: etravirine (TMC125) and darunavir (TMC114) in treatment ...  Feb 13, 2006
In the control arm, the most commonly used comparator PIs were lopinavir/ritonavir (Kaletra), saquinavir (Invirase), amprenavir (Agenerase) and atazanavir ... - Aidsmap,

Roche to discontinue HIV treatment  09 Feb 2006
The company will instead focus its resources on Invirase, a tablet formulation of the drug that offers a more convenient and tolerable treatment regimen for ... - Pharmaceutical Business Review

Roche discontinues marketing of anti-HIV drug Fortovase  09 Feb 2006
The company also says a newer formulation of the active ingredient in the medication, sold as Invirase, has fewer side effects and a lower pill burden than ... - The Advocate

Roche to Focus Resources on Availability of Invirase, Now ...  Feb 6, 2006
...and distribution of Fortovase®, the soft-gel formulation of the HIV protease inhibitor saquinavir, due to the continued availability of the Invirase® 500 mg ... - DG News

Roche to Focus Resources on Availability of INVIRASE(R), Now ...  Feb 6, 2006
...and distribution of Fortovase(R), the soft-gel formulation of the HIV protease inhibitor saquinavir, due to the continued availability of the INVIRASE(R) 500 ... - International News Service

Roche To Stop Selling Protease Inhibitor Fortovase Because of ...  Feb 8, 2006
...as saquinavir -- in the US because of decreased demand for the drug and increased demand for a newer formulation of saquinavir, called Invirase, Reuters reports ... - Kaiser network.org

UPDATE 1-Roche to discontinue US sales of AIDS drug  Feb 6, 2006
Roche said its Invirase (saquinavir mesylate) HIV drug in 500 milligram tablet form is the preferred medicine as part of a combination treatment to prevent ... - Reuters

Multi-component drug delivery system: An emerging trend  Feb 8, 2006
...include amprenavir (Agenerase), nelfinavir (Viracept), saquinavir (Fortavase), indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase), and lopinavir ... - Express Pharma Pulse

Consiga la Gold Card American Express ahora  Feb 6, 2006
...[+]. (PRN) - Roche to Focus Resources on Availability of INVIRASE(R), Now Preferred Formulation of Saquinavir ... [+. PRN) - Tiny Pictures, Inc. ... - Bolsamania.com

Roche HIV drug move greeted with scepticism  Jan 12, 2006
...the HIV virus, which can lead to Aids. It is sold under the Invirase brand name. Campaigners have been calling on drug companies ... - Swissinfo

Roche offers help to local manufacturers to produce HIV medicine ...  Jan 12, 2006
Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan Africa ... - SocialFunds.com

Roche offers HIV drug expertise to poor nations  Jan 12, 2006
Roche said it would make its HIV protease inhibitors Invirase and Viracept available at no-profit prices for direct supplies from Roche Basel to LDCs and sub ... - MedIndia

This site is for informational purposes only--it does not offer medical advice or sell health products. If you need assistance, contact your physician or healthcare professional