Recent news on Itraconazole

Itraconazole- A Potential Inhibitor Of Tumor-Related Angiogenesis  -  May 3, 2007
Medi News Direct,Itraconazole (Sporanox® | Janssen pharmaceutica), an antifungal drug commonly used against toenail infections, can also inhibit the proliferation of blood

MethylGene Presents Preclinical Data for its Clinical Candidate ...  -  May 24, 2007
WM Experts (press release),Data demonstrated that when the combinations of MGCD290 and itraconazole or voriconazole are used against C. glabrata, the post-antifungal effects and

Anti-fungal drug can also block angiogenesis  -  Apr 29, 2007
NewKerala.com,Researchers at Johns Hopkins have discovered that in mice, induced to have excess blood vessel growth, treatment with itraconazole reduced blood vessel

Anti-fungal Drug Block Angiogenesis  -  May 1, 2007
MedIndia,New Research at Johns Hopkins have discovered that in mice itraconazole reduced blood vessel growth by 67 percent compared to placebo.

Drug prevents blood vessel growth  -  Apr 29, 2007
PRESS TV,The drug, itraconazole, is already Food and Drug Administration (FDA) approved for human use, which may fast-track its availability as an antiangiogenesis

Common anti-fungal drug found to stop blood vessel growth  -  May 1, 2007
Cancer Research UK - News & Resources,Researchers at the John Hopkins University found that the drug itraconazole can block angiogenesis, the growth of new blood vessels commonly seen in cancers

Antifungal drug stops cancer  -  Apr 29, 2007
Baltimore Examiner,The drug, itraconazole, is FDA approved for human use, which may fast-track its availability as an anti-cancer drug. “We were surprised, to say the least,

Toenail fungus medicine may treat cancer  -  Apr 28, 2007
Daily Georgian Times,US researchers say itraconazole, a drug commonly used to treat toenail fungus, can also block the growth of new blood vessels in cancer.

Toenail fungus medicne may treat cancer  -  Apr 27, 2007
ImediNews,BALTIMORE, April 27 (UPI) — US researchers say itraconazole, a drug commonly used to treat toenail fungus, can also block the growth of new blood vessels in

Toenail fungus medicne may treat cancer  -  Apr 27, 2007
United Press InternationalBALTIMORE, April 27 (UPI) -- US researchers say itraconazole, a drug commonly used to treat toenail fungus, can also block the growth of new blood vessels

Toenail fungal drug may work as an anti-cancer drug  -  May 2, 2007
TopCancerNews.com,The drug, itraconazole, is FDA approved for human use, which may fast-track its availability as an anti-cancer drug. If you are interested in reading more

Ciclopirox 8% Nail Lacquer Topical Solution for the Treatment of ...  -  May 16, 2007
Journal of the American Podiatric Medical Association (subscription)9 , 10 Imidazole oral antifungal agents, such as ketoconazole, fluconazole, and itraconazole, may act as competitive inhibitors of the cytochrome P-450 3A4

Atlan International Holdings Corp.  -  May 4, 2007
Ad-Hoc-News (Pressemitteilung),...drug bioavailability from topical applications based on modification of solvency profile of drugs that have limited solubility, eg itraconazole.

Recommendations for Primary Care of the Patient With Cancer  -  Apr 30, 2007
Medscape (subscription)Antifungal treatments (nystatin [swish and swallow] or fluconazole or itraconazole [orally]) should be given for thrush. Xerostomia should be treated with

Kyowa Hakko Kogyo submits NDA for Parkinson's drug  -  Apr 30, 2007
Pharma Times (subscription),...hit by price cuts of 6.7% introduced in Japan in April last year and a steep decline in revenues from the oral antifungal Itrizole (itraconazole).

Multiple-Triazole–Resistant Aspergillosis  -  Apr 4, 2007
New England Journal of Medicine (subscription),Since the first description of itraconazole resistance in Aspergillus fumigatus, 1 three amino acid substitutions in the 14- sterol demethylase cyp51A gene,

Posaconazole for Azole-Refractory Candidiasis in Patients with HIV ...  -  Mar 29, 2007
Therapeutics Daily (subscription) (press release),...candidiasis (OPC) or esophageal candidiasis (EC) who had not responded to standard courses of either fluconazole or itraconazole were treated with

Retriever's allergies can be eased  -  Apr 20, 2007
DetNews.com,Antifungals such as ketoconazole or itraconazole are also helpful. Omega 3 and omega 6 fatty acids provide relief from itching. When using special shampoos,

Get Rid of Athlete’s Foot: Learn How to Totally Cure Athlete's Foot  -  Apr 19, 2007
American Chronicle,...your doctor will most probably prescribe topical creams and ointments that contain miconazole, clotrimazole, terbinafine or itraconazole.

Helix BioMedix Antifungal Lipo-Peptides Show Promise in ...  -  Apr 12, 2007
Drug Newswire (press release),...which was developed and used earlier at the Center for Medical Mycology in the pre-clinical evaluation of terbinafine and itraconazole,

Scientific Results Presented at ECCMID Demonstrate Well ...  -  Apr 5, 2007
WebWire (press release),...at relevant plasma concentrations potent efficacy against several strains of Aspergillus fumigatus including an itraconazole-resistant strain (P1951).

Posaconazole successful in treating fluconazole- and itraconazole ...  -  Feb 15, 2007
Aidsmap,Alternative treatments include itraconazole and voriconazole (which may be hampered by cross-resistance and drug interactions), and the more highly toxic

Noxavil® May Be Superior for Prevention of Fungal Infections in ...  -  Jan 29, 2007
Cancer Consultants (press release),Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. New England Journal of Medicine 2007; 356:348-359.

Varning för olagligt erektionspreparat  -  Feb 14, 2007
Rundradion,Additional monitoring of your dose or condition may be needed if you are taking other medicines for impotence, azole antifungals (eg, itraconazole,

Schering-Plough Reports Financial Results for 2006 Fourth Quarter ...  -  Jan 29, 2007
PR Newswire (press release),...triazole antifungal agent, for the treatment of oropharyngeal candidiasis (OPC), including infections refractory to itraconazole and/or fluconazole.

NWLS Signs Exclusive License Agreement Relating to Innovative ...  -  Jan 16, 2007
Fast Pitch! (press release)...drug bioavailability from topical applications based on modification of solvency profile of drugs that have limited solubility, eg itraconazole.

Gastrointestinal Medications  -  Jan 5, 2007
Psychosomatics (subscription)68 Known CYP 3A4 inhibitors such as ketoconazole 69 and itraconazole 70 have been shown to significantly increase the plasma levels of budesonide.

SIBUTRAMINE , sibutramine 15mg , sibutramine side effects , cheap ...  -  Dec 27, 2006
Indymedia Colombia,5Erythromycin, clarithromycin, itraconazole, or sibutramine food, usually in the fioricet of chronic pain Association as you remember.

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),If treatment with itraconazole, ketoconazole, erythromycin, clarithromycin or telithromycin is unavoidable, therapy with VYTORIN should be suspended during

Nigeria: Ask Your Doctor Candidiasis  -  Dec 14, 2006
AllAfrica.com,For more severe cases, itraconazole or fluconazole may be taken - these are systemic antifungals, meaning they are absorbed through the intestine and reach

Study of Dasatinib or 800 Mg of Imatinib Mesylate Shows Patients ...  -  Dec 14, 2006
DG NewsDrugs that may increase dasatinib concentrations are: CYP3A4 inhibitors (eg, ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir,

Helix BioMedix Antifungal Lipo-Peptides Show Promise in ...  -  Dec 4, 2006
Drug Newswire (press release),...which was developed and used earlier at the Center for Medical Mycology in the pre-clinical evaluation of terbinafine and itraconazole,

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),If treatment with itraconazole, ketoconazole, erythromycin, clarithromycin or telithromycin is unavoidable, therapy with VYTORIN should be suspended during

International Approvals: Byetta and Noxafil  -  Nov 28, 2006
Medscape (subscription)...allowing its use for the treatment of oropharyngeal candidiasis (including cases that are refractory to itraconazole and/or fluconazole therapy) in the

Noxafil(R) (Posaconazole) Oral Suspension Approved in European ...  09 Nov 2006
Aspergillus infections in patients receiving NOXAFIL prophylaxis when compared to control patients on standard azole therapy (fluconazole or itraconazole). ... -Yahoo! News (press release) Published Data Showed Vardenafil Treated Erectile Dysfunction ...  Nov 3, 2006
In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended, and ... -DG News my private weblog  Oct 31, 2006
...of levitra Glaxo to market the drug is cialis levitra viagra vs vs men and failed men.by comment levitra movable post powered type or itraconazole (such as ... -Digital Divide Network, Hoof Wall Wonders  Nov 3, 2006
The bleach products, DMSO, Fungidye, and other more classic antifungal drugs such as miconazole, clotrimazole, and itraconazole should be of benefit. ... -TheHorse.com, Schering-Plough Announces FDA Approval of NOXAFIL(R) (Posaconazole ...  Oct 25, 2006
...approved NOXAFIL(R) (posaconazole) Oral Suspension for the treatment of oropharyngeal candidiasis (OPC), including infections refractory to itraconazole and/or ... -Drug Newswire (press release), FDA Approves NOXAFIL® for Treatment of Oropharyngeal Candidiasis  Oct 24, 2006
...approved NOXAFIL® (posaconazole) Oral Suspension for the treatment of oropharyngeal candidiasis (OPC), including infections refractory to itraconazole and/or ... -EndoNurse, Barrier Therapeutics Announces Third Quarter 2006 Financial ...  Oct 31, 2006
The trial is expected to include approximately 1,200 patients and compares Hyphanox to currently marketed itraconazole capsules and to placebo. ... -Market Wire (press release) Schering-Plough Announces FDA Approval of NOXAFIL(R) (Posaconazole ...  Oct 23, 2006
...approved NOXAFIL(R) (posaconazole) OralSuspension for the treatment of oropharyngeal candidiasis (OPC), includinginfections refractory to itraconazole and/or ... -Earthtimes.org Schering-Plough Gets New Noxafil FDA OK  Oct 23, 2006
The new approval covers the treatment of oropharyngeal candidiasis and infections that don't respond to the antifungal medications itraconazole or fluconazole. ... -Houston Chronicle, Schering-Plough Reports FDA Approval For NOXAFIL To Treat ...  Oct 23, 2006
...fluconazole, as well as a non- comparative study of NOXAFIL in HIV-infected patients with OPC that was refractory to treatment with fluconazole or itraconazole ... -Trading Markets, Publicado: Sab Oct 14, 2006 5:01 pm Asunto: Unless directed to do ...  Oct 14, 2006
...mononitrate iet of mostly processed foods with some sugars and red isotretinoin yes to a diet of mostly fresh foods, with few sugars o itraconazole dyes of any ... -Shell Security, Noxafil Approved for New Indication  Oct 24, 2006
Plough’s Noxafil (posaconazole) oral suspension for the treatment of oropharyngeal candidiasis, including infections refractory to itraconazole and/or ... -Facts and Comparisons, Market Report -- In Play (WIRES)  Oct 23, 2006
...that the FDA has approved Noxafil Oral Suspension for the treatment of oropharyngeal candidiasis, including infections refractory to itraconazole and/or ... -MSN Money Go-Ahead Given to Four Drugs for Cardio Conditions, Eczema, MS ...  Oct 23, 2006
Schering-Plough’s Noxafil (posaconazole) Oral Suspension was approved for oropharyngeal candidiasis, including infections refractory to itraconazole and/or ... -Genetic Engineering News (press release), Schering-Plough Announces FDA Approval Of NOXAFIL(R) (Posaconazole ...  Sep 19, 2006
Suspension 200 mg three times daily (n=304) to pooled standard azole therapies (fluconazole oral suspension 400 mg once daily or itraconazole oral solution 200 ... -Medical News Today

European Union's CHMP Adopts Positive Opinion For NOXAFIL(R) ...  Sep 23, 2006
...label study compared NOXAFIL Oral Suspension 200 mg three times daily (n=304) to fluconazole suspension 400 mg once daily (n=240) or itraconazole oral solution ... -Medical News Today

Schering-Plough: new fungicide gets US approval  Sep 20, 2006
Noxafil's registration trials have demonstrated a superior prophylactic effect against IFIs compared to pooled fluconazole or Sporanox (itraconazole). ... -Pharmaceutical Business Review

Fungal nail infections  Sep 16, 2006
...or longer for toenails. Oral medications such as itraconazole or terbinafine may be taken for several months. The medication will ... -Malaysia Star

Topical antifungal may help toenails  Aug 25, 2006
Two antifungal pills, terbinafine and itraconazole, work well in most people but have been known in rare situations to cause serious liver problems such as ... -Baltimore Sun

- Study of Chronic-Phase Patients with Chronic Myelogenous ...  -  Dec 11, 2006
PR Newswire (press release),Drugs that may increase dasatinib concentrations are: CYP3A4 inhibitors (eg, ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir,

International Approvals: Accomplia and Noxafil  -  Nov 20, 2006
Medscape (subscription)Results showed that posaconazole prophylactic therapy yielded a reduction in treatment failure compared with fluconazole/itraconazole, as defined by a

Helix BioMedix Antifungal Lipo-Peptides Show Promise in ...  -  Dec 4, 2006
Drug Newswire (press release),...which was developed and used earlier at the Center for Medical Mycology in the pre-clinical evaluation of terbinafine and itraconazole,

International Approvals: Byetta and Noxafil  -  Nov 28, 2006
Medscape (subscription)...allowing its use for the treatment of oropharyngeal candidiasis (including cases that are refractory to itraconazole and/or fluconazole therapy) in the

Happy feet grow elusive with age  -  Nov 21, 2006
Rocky Mountain News,Two oral prescription drugs - itraconazole and terbinafine - may clear the infection in about half the people who take them. The drugs can be toxic to the

Jane Brody: Nonsurgical approaches for keeping active feet in the ...  -  Nov 21, 2006
Naples Daily News,Two oral prescription drugs — itraconazole (Sporanox) and terbinafine (Lamisil) — taken for several months, may eventually clear the infection in about half

Topical antifungal may help toenails  Aug 25, 2006
Two antifungal pills, terbinafine and itraconazole, work well in most people but have been known in rare situations to cause serious liver problems such as ... -Baltimore Sun

Grapefruit-Drug Interactions  Aug 15, 2006
A number of medications (eg, angiotensin receptor blockers, buspirone [BuSpar], estrogens, fexofenadine [Allegra], itraconazole [Sporanox], sildenafil [Viagra ... -American Family Physician

Rimonabant, a new drug for weight loss  Aug 22, 2006
Rimonabant should be used with caution in combination with potent CYP3A4 inhibitors ( eg Ketoconazole, Itraconazole, Ritonavir, Telithromycin, Clarithromycin ... -Xagena.it

Multiple Medication Use in General Practice and Psychiatry: So ...  Aug 23, 2006
Itraconazole (Sporanox), an antifungal agent, is also a potent inhibitor of CYP3A4 and can increase levels of buspirone (BuSpar) and haloperidol (Haldol ... -Psychiatric Times

Blastomycosis: the nightmare at the cottage  Aug 17, 2006
...blastomycosis. His medical team put him on a six-month regime of a pricey drug called itraconazole, and now he's fully recovered. ... -Macleans

FDA Approves Sprycel (Dasatinib) With Two Indications  Jun 29, 2006
Drugs that may increase dasatinib concentrations are: CYP3A4 inhibitors (eg, ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir, atazanavir ... -DG News



Star of the Batman Television Series Leads Crusade for Baby ...  16 May 2006
Do not take UROXATRAL if you have liver problems or if you are taking the antifungal drugs ketoconazole or itraconazole, or HIV drugs like ritonavir. ... - PharmaLive.com

Fungal prosthetic mitral valve endocarditis caused by ...  May 9, 2006
...mean inhibitory concentrations of 4 µg/mL to amphotericin B, 1 µg/mL to terbinafine, 8 µg/mL to voriconazole, and greater than 8 µg/mL to itraconazole. ... - The Journal of Thoracic and Cardiovascular Surgery

Off-Label Drug Use  May 2, 2006
Many of the ophthalmic (eye) drugs are from human medicine, particularly ones such as miconazole, natamycin, and itraconazole used for treating fungal ... - TheHorse.com

Sore Feet a Sure Sign of Aging  Apr 21, 2006
...including fungal nails and athlete's foot, are Lamisil (terbinafine) made by Novartis Pharmaceuticals of East Hanover, NJ, and Sporanox (itraconazole), made by ... - SeniorJournal.com

Astellas Launches VAPRISOL(R) for the Treatment of Euvolemic ...  Apr 26, 2006
The co-administration of VAPRISOL with potent CYP3A4 inhibitors, such as ketoconazole, itraconazole, clarithromycin, ritonavir, and indinavir, is also ... - Yahoo! News





Topical and Oral Combination Therapy for Toenail Onychomycosis  Mar 28, 2006
4 Olafsson et al 5 showed that 23% of terbinafine-treated patients and 53% of itraconazole-treated patients experienced a relapse or reinfection after 5 years ... - Journal of the American Podiatric Medical Association

Nonoperative Treatment of Vertebral Blastomycosis Osteomyelitis ...  Apr 3, 2006
After four weeks of Abelcet treatment, treatment with oral itraconazole (400 mg per day) was started and was continued for a total of six months. ... - Journal of Bone and Joint Surgery

60 or 70 - Remain Sexually Fit  Apr 10, 2006
...dose or condition may be needed if you are taking any other medicine for erectile dysfunction; certain antifungal medicines such as itraconazole or ketoconazole ... - LiveArticles.org

ACP: Garlic, Ginseng, Ginkgo Biloba, and Ginger All Bad Actors ...  Apr 9, 2006
...likely to interact with Coumadin include erythromycin, amiodarone, Diflucan (fluconazole), Nizoral (keotoconazole), Sporanox (itraconazole), and mentronidazole ... - MedPage Today

Data Analysis Showed VYTORIN(R) (Ezetimibe/Simvastatin) ...  Mar 13, 2006
The use of VYTORIN concomitantly with the potent CYP3A4 inhibitors itraconazole, ketoconazole, erythromycin, clarithromycin, telithromycin, HIV protease ... - International News Service

New treatment for oral thrush as effective as current standard of ...  Mar 29, 2006
...available. The current standards of care are fluconazole or itraconazole, but resistance to these drugs can develop. Laboratory ... - Aidsmap

Study Shows Levitra Treats Erectile Dysfunction Effectively in Men ...  Mar 22, 2006
In patients taking certain medications such as ritonavir, indinavir, ketoconazole, itraconazole, and erythromycin, lower doses of Levitra are recommended, and ... - DG News

Taking Care of Your Feet  Mar 20, 2006
...including fungal nails and athlete's foot, are Lamisil (terbinafine) made by Novartis Pharmaceuticals of East Hanover, NJ, and Sporanox (itraconazole), made by ... - FDA.gov



Profits up, but sales down at J&J in 4Q  Jan 25, 2006
...fentanyl transdermal system) for chronic pain, analgesic Ultracet (acetaminophen/tramadol hydrochloride), the antifungal Sporanox (itraconazole) and J&J's ... - Pharma Times (subscription)

(PZ) Novartis Delivers Strong Performance with Record Results in ...  Jan 18, 2006
In the US, sales were slightly higher, further increasing its leadership despite the launch in 2005 of a generic version of the competitor itraconazole. ... - Houston Chronicle

FDA Approves EMEND(R) (aprepitant), in Combination with Other ...  Jan 11, 2006
Consequently, concomitant administration of EMEND with strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, nefazodone, troleandomycin, clarithromycin ... - Business Wire

Johnson & Johnson: Fourth Quarter and Year End 2005 Financial ...  Jan 24, 2006
...system), a transdermal patch for chronic pain; ULTRACET® (acetaminophen/tramadol hydrochloride), an analgesic; SPORANOX® (itraconazole), an antifungal; and ... - PharmaLive.com

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