Recent news on Leuprolide

The Smallcap Newsletter QualityStocks Report 5/22/07  -  May 22, 2007
TransWorldNews (press release),Leuprolide is one of the most widely used anti-cancer agents for advanced prostate cancer in men. Leuprolide is currently available only in injectable,

DOR BioPharma Reports First Quarter 2007 Financial Results  -  May 16, 2007
WM Experts (press release),...a clinical development program in humans with its Lipid Polymer Micelle ("LPMâ„¢") oral drug delivery technology for the oral delivery of leuprolide.

FDA Advisory Panel Reviews DOR BioPharma's orBec(R) for Treatment ...  -  May 9, 2007
Genetic Engineering News (press release),Polymer Micelle ("LPM(TM)") oral drug delivery technology for the oral delivery of leuprolide for the treatment of prostate cancer and endometriosis.

Efficacy and Safety of Histrelin Subdermal Implant in Children ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,...yr (naive) or 2–11 yr (previously treated) with clinical evidence of CPP and a pretreatment pubertal response to leuprolide stimulation were eligible.

Ranbaxy Q1 2007 Net Profit Rises 79% to Rs.129 Crores  -  Apr 29, 2007
India PRwire (Press Release),...(Nitrofurantoin modified release) developed using the Company's R&D capabilities & Eligard 22.5mg & 45mg (Leuprolide Depot), in-licensed from QLT Inc.,

DOR's oral leuprolide to start trials mid-year  -  Apr 11, 2007
In-PharmaTechnologist.com,DOR said a Phase I safety, tolerability and pharmacokinetic study with leuprolide, incorporated in the company's Lipid Polymer Micelle (LPM) drug delivery

DOR BioPharma Announces Initiation of Clinical Development Program ...  -  Apr 4, 2007
PharmaLive.com (press release),The LPMT system is a platform technology designed to allow for the oral administration of drugs such as leuprolide that are water-soluble but poorly

DOR BioPharma to test oral drug delivery system  -  Apr 6, 2007
South Florida Business Journal,The drug tested in those studies was Leuprolide, a common treatment of prostate cancer in men and endometriosis - a condition where cells from the uterus

Preclinical Data on Cytogen's Technology to be Reported at the ...  -  Mar 29, 2007
Business Wire (press release),Presentation Date and Time: Sunday, April 15, 2007, 1:00 PM - 5:00 PM Abstract #1497: Oral delivery of leuprolide in a rat model using poly-lactide-glycolic

Neurocrine Biosciences Announces Positive Phase II Results With ...  -  Apr 12, 2007
Drug Newswire (press release),Although indicated for endometriosis, medical therapies such as the injectable GnRH agonists leuprolide or injectable progesterone are associated with a

Preclinical Data on Cytogen's Technology to be Reported at the ...  -  Mar 29, 2007
Nanotechnology News (press release)...in preclinical models, and successful in vivo delivery of nanoparticle-encapsulated insulin and leuprolide in animal models has been demonstrated.

Ranbaxy in-licences urology drug from US firm  -  Jan 29, 2007
Business Standard,Niftran 100mg capsules (Nitrofurantoin modified-release) has been developed using the company's R&D capabilities, and Eligard 22.5mg & 45mg (Leuprolide

Ranbaxy launches two urology products in India  -  Jan 29, 2007
Afternoon Dispatch & Courier,The drugs — Niftran 100 mg capsules (Nitrofurantoin modified release) and Eligard 22.5mg and 45mg (Leuprolide Depot) — were developed using its domestic

Cash infusion could revive work on Alzheimer's drug  -  Jan 27, 2007
News & Observer,Memryte, which is implanted under the skin, consists of a small, biodegradable tube filled with leuprolide acetate, an experimental booster of approved

Play Texas hold 'em for prostate cancer  -  Feb 8, 2007
YourHub.com,He was Principal Investigator (PI) on the study leading to approval of leuprolide, which is the top hormone therapy used to fight prostate cancer.

Tolmar in sale-leaseback deal to snap up QLT USA  -  Feb 6, 2007
In-PharmaTechnologist.com,Sales of Eligard (leuprolide), approved for the palliative treatment of advanced prostate cancer, were temporarily suspended following patent litigation for

Ranbaxy launches 2 NDDS Urology products in India  -  Feb 1, 2007
Moneycontrol.com,Niftran 100mg Capsules (Nitrofurantoin modified release) developed using the Company’s R&D capabilities & Eligard 22.5mg & 45mg (Leuprolide Depot),

People magazine: Don't stop, get a shot  -  Jan 30, 2007
WorldNetDaily,She can expect her body to be barraged with estrogen, progesterone, leuprolide acetate, follicle stimulating hormone, human menopausal gonadotropins and

There Are Currently No Less Than 220 Emerging Therapeutics ...  -  Jan 16, 2007
PharmaLive.com (press release),Finally, leuprolide was approved by FDA in January 2002 for the palliative treatment of advanced prostate cancer. One example of market penetration in this

There Are Currently No Less Than 220 Emerging Therapeutics ...  -  Jan 15, 2007
Genetic Engineering News (press release),Finally, leuprolide was approved by FDA in January 2002 for the palliative treatment of advanced prostate cancer. One example of market penetration in this

Prostrate Cancer Treatment Affects Penile Length  -  Jan 11, 2007
MedIndia,These patients were studied over a period of 5 years when they were receiving three doses of leuprolide or goserelin injections once in three months.

Neurocrine Biosciences Announces Positive Results From Second ...  -  Jan 9, 2007
PipelineReview.com (press release),Although indicated for endometriosis, medical therapies, such as the injectable GnRH agonist leuprolide or injectable progesterone, are associated with a

Young breast cancer patients test super-hormone treatment  -  Dec 26, 2006
Wilkes Barre Times-Leader,The drugs include triptorelin, goserelin, leuprolide and buserelin, sold as Lupron, Zoladex, Prostap and other brands. Such drugs have been around for 20

Young breast cancer patients test super-hormone treatment  -  26 Dec 2006
Wilkes Barre Times-Leader,The drugs include triptorelin, goserelin, leuprolide and buserelin, sold as Lupron, Zoladex, Prostap and other brands. Such drugs have been around for 20

Eligard(R) (leuprolide acetate) 6-Month Formulation Approved in ...  -  Dec 1, 2006
DG NewsThe Atrigel technology allows for sustained delivery of leuprolide acetate for periods ranging from one to 6 months. Eligard works by lowering the levels of

Cytogen issued new patent covering oral drug delivery agents  -  Nov 27, 2006
News-Medical.net,For more information, a white paper titled "Active-transport peptides induce GIT transport of nanoparticles containing leuprolide and insulin in an in vivo

Germany OK's QLT's cancer treatment  -  Dec 1, 2006
United Press InternationalEligard, which consists of the LHRH agonist leuprolide combined with QLT's Atrigel delivery system, has generated $84 million in worldwide sales through the

Super-hormone treatments could reduce risk of recurrence  -  Dec 18, 2006
NewsOK.com (subscription),The drugs include triptorelin, goserelin, leuprolide and buserelin, sold as Lupron, Zoladex, Prostap and other brands.

Cancer patients test new treatment  -  Dec 17, 2006
Houston Chronicle,The drugs include triptorelin, goserelin, leuprolide and buserelin. Such drugs have been around for 20 years and are used more in Europe than in the United

Drug-induced menopause may save lives  -  Dec 18, 2006
Charlotte Observer,The drugs include triptorelin, goserelin, leuprolide and buserelin. Such drugs have been around for 20 years and are used more in Europe than in the US,

Hormones used in breast Cancer fight  -  Dec 17, 2006
El Paso Times,...goserelin, leuprolide and buserelin, sold as Lupron, Zoladex, Prostap and other brands. Such drugs have been around for 20 years and are used more in Europe

Valera Pharmaceuticals Reports Third Quarter 2006 Financial ...  Nov 8, 2006
The current US market for treating CPP is estimated at over $75 million and is dominated by intramuscular injections of leuprolide administered every three to ... -Market Wire (press release) Repros Reveals Preliminary Clinical Data Of Proellex In Treatment ...  Oct 24, 2006
The study included three dose levels of Proellex and Leuprolide Injection.Leuprolide Injection is a GnRH agonist also known as Lupron commonly used for the ... -Trading Markets, Abbott Reports Strong Third-Quarter Results, Announces $2.5 ...  Oct 18, 2006
...$132 9.3 $17 11.9 $149 9.6 Biaxin (clarithromycin) $16 (61.6) $122 (10.5)(d) $138 (22.1) Omnicef $135 55.6 --- -- $135 55.6 Leuprolide --- -- $58 3.7(e) $58 ... -Yahoo! News (press release) Voyager Pharmaceuticals’ Financial Plight Is A True Tragedy ...  Oct 20, 2006
...has to wait for the Voyager principals to get the firm’s financial house in order – or finds another solution - before its “leuprolideâ€? wins approval. ... -Local Tech Wire, Repros Reports Partial Interim Assessment of Phase 2 Study of ...  Oct 24, 2006
The positive control was Leuprolide Injection (Lucrin(R)), a GnRH agonist also known as Lupron(R), commonly used for the treatment of endometriosis. ... -PharmaLive.com (press release), COMUNICADO: Una encuesta revela malentendidos médicos de la ...  Oct 31, 2006
Lancet 2000; 355: 1491-1498. [4] Crawford ED, Eisenberger MA, McLeod DG et al. A controlled trial of leuprolide with and without flutamide in prostatic cancer. ... -Terra España, Several drugs show promise for alzheimer's  Oct 17, 2006
...genetics. For example, leuprolide, the prostate-cancer drug that is being tested in Alzheimer's patients by Voyager Pharmaceuticals Inc. ... -Pittsburgh Post Gazette, Prostate Cancer Hormone Therapy May Have Unwelcome Side Effects  Oct 30, 2006
...agonists. Common drugs in this class include leuprolide (Lupron, Viadur, Eligard), goserelin (Zoladex), and triptorelin (Trelstar). ... -ACS News Center, DURECT Provides an Update to the Memryte(TM) Program Under ...  Oct 24, 2006
Memryte utilizes DURECT's proprietary DURIN technology to provide sustained release of the peptide leuprolide acetate and is based on Voyager's patented method ... -Drug Newswire (press release), DURECT Says Voyager Closes Trial Of Alzheimer's Drug Memryte ...  Oct 19, 2006
Memryte utilizes DURECT's proprietary DURIN technology to provide sustained release of the peptide leuprolide acetate and is based on Voyager's patented method ... -Trading Markets, Estrogen Preserves Working Memory in Pre- but Not Postmenopausal ...  Oct 16, 2006
The second study was a prospective design and included 25 premenopausal women with an average age of 36 who received leuprolide acetate depot (LAD), a ... -Medscape (subscription) Repros Reports Partial Interim Assessment of Phase 2 Study of ...  Oct 24, 2006
The positive control was Leuprolide Injection (Lucrin ® ), a GnRH agonist also known as Lupron®, commonly used for the treatment of endometriosis. ... -Business Wire (press release), Increased Co-Payments For Expensive Specialty Drugs Won't Cut ...  Sep 13, 2006
For example 1,943 patients with prostate cancer spent $6.3 million for leuprolide acetate (Lupron), or about $3,200 a year per patient. ... -All American Patriots

Neurocrine Biosciences Announces Results From Follow-Up Phase II ...  Sep 13, 2006
Although indicated for endometriosis, medical therapies, such as the injectable GnRH agonist leuprolide or injectable progesterone, are associated with a range ... -Medical News Today

Cougar Biotechnology Appoints Dr. Russell Ellison to Board of ...  Sep 11, 2006
...where he was responsible for several key oncology products including Eloxatin (oxaliplatin) for colorectal cancer and Eligard (leuprolide acetate for ... -Genetic Engineering News

How to Manage Hot Flashes as a Cancer Patient  Sep 1, 2006
Prostate cancer patients on hormonal therapy – Men may experience hot flashes if they take drugs such as Lupron Depot ® (leuprolide) or Zoladex ® (goserelin ... -CancerWise

Eligard(R) (leuprolide acetate) 6-Month Formulation Approved in ...  -  Dec 1, 2006
DG News...treatment for advanced prostate cancer, incorporates a luteinizing hormone-releasing hormone agonist, or LHRH agonist -- known as leuprolide acetate with QLT ...

Eligard(R) six-month formulation approved in Germany  -  Nov 30, 2006
Yahoo! News (press release)...treatment for advanced prostate cancer, incorporates a luteinizing hormone-releasing hormone agonist, or LHRH agonist, known as leuprolide acetate with QLT ...

European Pharmaceutical Company, GP-Pharm, Selects DATATRAK  -  Nov 17, 2006
Earthtimes.org..."Now we are working with DATATRAK in our phase III clinical trial of the new Leuprolide 3.75 mg depot formulation and soon we will begin in US the clinical ...

Cytogen Receives Patent Covering Oral Drug Delivery Agents  -  Nov 27, 2006
AZoNano.com,Cytogen's delivery agents to these receptors has been confirmed in preclinical models, and successful in vivo delivery of both insulin and leuprolide in animal ...

Germany OK's QLT's cancer treatment  -  Dec 1, 2006
United Press InternationalEligard, which consists of the LHRH agonist leuprolide combined with QLT's Atrigel delivery system, has generated $84 million in worldwide sales through the ...

Drop in estrogen impairs memory  Aug 23, 2006
Sherwin and her colleagues studied 25 women, ages 25 to 40, who were taking a drug called leuprolide acetate depot as part of treatment for benign ... -Macleans

Researchers Link Estrogen Levels, Memory Loss In Younger Women  Aug 23, 2006
In the course of their regular treatment, these women were given leuprolide acetate depot (Lupron), a drug that chemically suppresses ovarian function and ... -eMaxHealth.com

Applying brakes to symptoms of Alzheimer's with a tiny implant  Jul 26, 2006
Leuprolide acetate, the medicine which has been in use for over two decades to treat prostate cancer is now being used inside the implant and research has ... -MedIndia

Valera Pharmaceuticals Reports Second Quarter 2006 Financial ...  Jul 27, 2006
The US CPP therapy market is estimated at over $75 million annually and is dominated by intramuscular injections of leuprolide administered to afflicted ... -Business New Jersey (subscription)



Leuprolide Acetate Stabilizes Cognitive and Functional Decline in ...  16 May 2006
RALEIGH, NC, May 16 /PRNewswire/ -- Leuprolide acetate, when used in conjunction with standard Alzheimer's therapy, was shown to stabilize the cognitive and ... - Yahoo! News

(PRN) - Answers.com Releases 1-Click Answers 2.0 ... [+]  16 May 2006
...[+]. (PRN) - Leuprolide Acetate Stabilizes Cognitive and Functional Decline in Women With Alzheimer's Disease, Study Shows ... [+. ... - Bolsamania.com

Voyager Pharmaceutical Corporation Completes Second Phase II ...  May 3, 2006
Voyager Pharmaceutical Corporation announced Wednesday the completion of a Phase II study that assessed the safety and efficacy of leuprolide acetate in the ... - Yahoo! News

Voyager Pharmaceutical Corporation Completes Second Phase II ...  May 3, 2006
RALEIGH -- Voyager Pharmaceutical Corporation has completed a Phase II study that assessed the safety and efficacy of leuprolide acetate in the treatment of ... - Carolina Newswire

Abbott Reports First Quarter Results Led by Strong Medical ...  Apr 19, 2006
...$125 2.5 (d) $207 5.2 TriCor $205 20.0 --- -- $205 20.0 Omnicef $143 5.9 --- -- $143 5.9 Synthroid $111 (9.9) $15 18.2 $126 (7.4) Leuprolide --- -- $53 0.4 ... - MSN Money

Hormonal Therapy for Prostate Cancer Decreases Insulin Sensitivity  May 1, 2006
Among men with locally advanced or recurrent prostate cancer, short-term treatment with Lupron Depot® (leuprolide) and Casodex® (bicalutamide) increased body ... - Cancer Consultants

Lawsuit alleges co-founder derailed IPO  May 5, 2006
At the time, Bowen was a physician practicing in Naples, Fla., and the holder of a patent on leuprolide acetate as a possible treatment for Alzheimer's disease ... - News & Observer

Voyager Pharmaceutical Corporation to Present at the 9th ...  Apr 18, 2006
...information at Voyager Pharmaceutical Corporation, will discuss the stabilization of cognitive decline in AD following treatment with leuprolide acetate. ... - PR Newswire

New strategies for dealing with PMS  Apr 21, 2006
Medications like leuprolide that turn off ovulation are effective but have more side effects and carry the potential for long-term risks like osteoporosis. ... - Exeter News-Letter

GnRH Therapy Boosts Diabetes Risk in Men with Prostate Cancer  Apr 28, 2006
Hospital note that they prospectively followed 26 men with locally advanced or recurrent prostate cancer who underwent treatment with leuprolide depot and ... - Cancerpage.com

Neurocrine Biosciences Announces Positive Phase II Results With ...  Apr 27, 2006
Although indicated for endometriosis, medical therapies such as the injectable GnRH agonists leuprolide or injectable progesterone are associated with a range ... - Yahoo! News





Valera finishes early puberty study  11 Apr 2006
This market is dominated by Lupron Depot-PED (leuprolide acetate for depot suspension) produced by TAP Pharmaceutical Products, which involves intramuscular ... - Pharmaceutical Business Review

Enrollment Passes Midpoint in Voyager Pharmaceutical Corporation's ...  11 Apr 2006
Voyager's most advanced product candidate is VP4896, a proprietary, small, biodegradable implant that is comprised of leuprolide acetate and a polymer, in ... - PR Newswire

Valera Pharmaceuticals Completes Phase III Study of Its Twelve ...  Apr 6, 2006
This market is dominated by Lupron Depot-PED(R) (leuprolide acetate for depot suspension) from TAP Pharmaceutical Products, Inc. ... - International News Service

Lupron rival could return to market in May  Apr 6, 2006
US District Judge James Zagel of Chicago outlined key similarities of the drugs, both sustained-release versions of the same drug known as leuprolide acetate. ... - Chicago Tribune

Children With GERD Can Go Undiagnosed for Months  Mar 22, 2006
Pharmaceutical Company Limited, of Osaka, Japan. TAP markets Prevacid and Lupron Depot® (leuprolide acetate for depot suspension). - EndoNurse

Dendreon Names Christopher Lockett Head of Government Affairs  Mar 23, 2006
...and federal programs, including Medicare and Medicaid, as well as legislative issues on TAP's two leading products, Lupron Depot® (leuprolide acetate for ... - Yahoo! News

Children with Pediatric Gastroesophageal Reflux Disease (GERD) Can ...  Mar 22, 2006
Limited, of Osaka, Japan. TAP markets Prevacid and Lupron Depot(R) (leuprolide acetate for depot suspension). For more information ... - PharmaLive.com



Voyager Pharmaceutical Corporation Adds Six New Board Members  Mar 3, 2006
Voyager's most advanced product candidate is Memryte, a proprietary, small, biodegradable implant that is comprised of leuprolide acetate and a polymer, that ... - Carolina Newswire,

Depot Delivery System Maintains Steady Drug Level in Prostate ...  Feb 16, 2006
2006 (Reuters Health) - LA-2585 (Atrix Laboratories), an extended release subcutaneous formulation for the long-term delivery of leuprolide acetate, appears to ... - Cancerpage.com,

Rich Daly Joins TAP as Senior Marketing Executive  Feb 2, 2006
...overall marketing strategy and initiatives for TAP's current and future brands - including Prevacid® (lansoprazole) and Lupron Depot® (leuprolide acetate for ... - Yahoo! News

Rich Daly Joins TAP As Senior Marketing Executive  Feb 2, 2006
...marketing strategy and initiatives for TAP's current and future brands - including Prevacid(R) (lansoprazole) and Lupron Depot(R) (leuprolide acetate for depot ... - International News Service

Rich Daly Joins TAP as Senior Marketing Executive  Feb 2, 2006
...overall marketing strategy and initiatives for TAP's current and future brands - including Prevacid® (lansoprazole) and Lupron Depot® (leuprolide acetate for ... - Yahoo! News

Abbott Reports Record Sales, Earnings and Cash Flow in 2005  Jan 25, 2006
...$272 10.4 Ultane/Sevorane $91 14.7 $142 7.8 (b) $233 10.4 Omnicef $189 27.5 --- -- $189 27.5 Synthroid $141 (0.1) $15 9.8 $156 0.8 Leuprolide --- -- $54 (0.2 ... - MSN Money

Teva and Ivax Cleared to Complete Merger  Jan 27, 2006
In addition, generic distribution relationships that Ivax had with respect to certain amoxicillin, amoxicillin and clavulanate, leuprolide, and calcitriol ... - International News Service

Joseph DeVeaugh-Geiss, MD, Expands Role as Interim Chief Medical ...  Jan 16, 2006
...along with the Phase II and Phase III double-blind, placebo-controlled trials (ALADDIN) investigating the safety and effectiveness of leuprolide acetate as a ... - Biotech Intelligence

Teva-Ivax merger likely to create shifts in pharma sector  Jan 23, 2006
...also said that generic distribution relationships that Ivax had with respect to certain amoxicillin, amoxicillin and clavulanate, leuprolide, and calcitriol ... - Hindu Business Line

FTC gives Ivax and Teva final go-ahead for merger  Jan 23, 2006
In addition, the companies said generic distribution relationships Ivax had for certain amoxicillin, amoxicillin and clavulanate, leuprolide, and calcitriol ... - South Florida Business Journal

CMS Issues Final Rule on Competitive Acquisition of Medicare Part ...  Jan 20, 2006
Because all carriers have adopted LCA policies for injectable forms of leuprolide acetate, CMS has not included this product in the CAP. ... - Mondaq News Alerts

Voyager Pharmaceutical Names Interim Chief Medical Officer  Jan 16, 2006
DeVaugh-Geiss has been involved in all three phases of trials for Voyager’s drug leuprolide acetate, which is seen as a potential treatment for Alzheimer’s ... - Local Tech Wire

Preserving Competition, FTC Requires Divestitures Before Allowing ...  Jan 23, 2006
...to Par; 3) pergolide mesylate tablets from Teva, to be divested to Par; 4) estazolam tablets from IVAX, to be divested to Par; 5) leuprolide acetate injection ... - PharmaLive.com

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