Recent news on Levodopa

Parkinson's Disease  -  25 May 2007
WSOCtv.com,Levodopa (L-dopa) is a drug that nerve cells can use to make dopamine. However, the medication doesn't readily cross the blood-brain barrier.

Emory Participates in Study to Slow Progression of Parkinson's Disease  -  25 May 2007
DentalPlans.com,The study will enroll people who have been diagnosed with PD within the past five years and who have been treated for two years or less with levodopa or

Rotigotine As Levodopa Adjunct Is Effective In Advanced ...  -  May 3, 2007
Medical News Today,Transdermal rotigotine (Neupro) up to doses of 8 and 12 mg/day as adjunctive therapy to levodopa significantly decreases "off time" in patients with

No Improvement in Parkinson's Disease Symptoms With Coenzyme Q10  -  May 17, 2007
Medscape (subscription)The study included 131 individuals aged between 40 and 75 years with PD who were taking stable antiparkinsonian medication, with or without levodopa,

Submission of NDA for Istradefylline(KW-6002), an investigational ...  -  May 1, 2007
News-Medical.net,The symptoms of Parkinson's disease are treated primarily by dopamine replacement therapy with Levodopa or dopamine agonists.

Kyowa Hakko Kogyo submits NDA for Parkinson's drug  -  Apr 30, 2007
Pharma Times (subscription),Kyowa explained that the symptoms of Parkinson's are treated primarily by dopamine replacement therapy with levodopa or dopamine agonists, but long-term

Mind games  -  Apr 27, 2007
The Australian,Levodopa is the most widely used medication, improving symptoms in more than 80 per cent of people within six to eight weeks. Levodopa is converted into

High-Frequency Stimulation Provides Long-Term Efficacy for ...  -  May 4, 2007
DG NewsDrug dosages, and subsequently the levodopa-induced dyskinesias, were decreased by an average of 65%. This was linearly correlated to the preoperative

Fox: Take risks in fight vs. diseases  -  May 7, 2007
Boston Herald,...“Levodopa is the gold-standard treatment for Parkinson’s,� said Fox, who has established his own foundation to help fund studies of the disease that’s

Not about getting old ...  -  Apr 28, 2007
Malaysia Star,Dr Chew said a new three-in-one drug comprising a pharmacokinetically enhanced levodopa therapy comprising levodopa, carbidopa and entacapone was available

Drugs that adjust dopamine levels in the brain greatly affect how ...  -  Apr 29, 2007
News-Medical.net,One group was given levodopa, a drug that increases dopamine levels in the brain. Another took haloperidol, a dopamine receptor blocker.

Study Probes Parkinson Drugs' Effect on Motivation  -  Apr 26, 2007
Washington Post,One group received levodopa, which increases dopamine levels in the brain. The second group received a dopamine receptor blocker called haloperidol (which

Addition of Rotigotine Has Benefits in Late-Stage Parkinson's ...  -  May 3, 2007
DG NewsRotigotine was added to stable levodopa treatment. Primary efficacy measures compared changes from baseline to the end of week 24 in the number of daily

Fox asks researchers, investors to speed up treatments  -  May 9, 2007
Daily Mail - Charleston,..."Levodopa is the gold-standard treatment for Parkinson's ... But it's a little frustrating that the best drug we've got is one that's been around for 40

Lonnie Ali Champions 'Fight For MORE' Campaign  -  Apr 26, 2007
Earthtimes.orgDoctors may recommend adding Zelapar to levodopa/carbidopa treatment when patients are experiencing a reduced response to this therapy.

Fox wants faster action on research  -  May 8, 2007
Toronto Star,..."Levodopa is the gold-standard treatment for Parkinson's. But it's a little frustrating that the best drug we've got is one that's been around for 40 years.

Actor urges push to speed therapies  -  May 8, 2007
Boston Globe,..."Levodopa is the gold-standard treatment for Parkinson's . . . But it's a little frustrating that the best drug we've got is one that's been around for 40

Michael J. Fox pushes researchers, investors to speed therapies  -  May 7, 2007
Boston Herald,..."Levodopa is the gold-standard treatment for Parkinson’s ... But it’sa little frustrating that the best drug we’ve got is one that’s been around for 40

Fox urges spotlight on cures  -  May 8, 2007
Sun-Sentinel.com,..."Levodopa is the gold-standard treatment for Parkinson's. … But it's a little frustrating that the best drug we've got is one that's been around for 40

Fox urges researchers to speed therapies  -  May 7, 2007
Brocktown News,..."Levodopa is the gold-standard treatment for Parkinson‘s ... But it‘sa little frustrating that the best drug we‘ve got is one that‘s been around for 40

Michael J. Fox asks researchers, investors to speed therapies for ...  -  May 7, 2007
MIT Technology Review,...''Levodopa is the gold-standard treatment for Parkinson's ... But it's a little frustrating that the best drug we've got is one that's been around for 40

Fox appeals for new drugs to fight Parkinson’s  -  May 7, 2007
Canoe.ca,...“Levodopa is the gold-standard treatment for Parkinson’s ... But it’sa little frustrating that the best drug we’ve got is one that’s been around for 40

Neuroscience: The molecular wake-up call  -  May 23, 2007
Nature.com (subscription),In his experiment, Carlsson showed that dopamine — the chemical manufactured from levodopa, or L-dopa — acts as a neurotransmitter in the brain,

Michael J. Fox Foundation Awards $1 Million for Critical Next ...  -  May 23, 2007
PR Newswire (press release),Another team, led by Angela Cenci-Nilsson, MD, PhD, is following up on initial observations that levodopa-induced dyskinesia results in part from

Blood Levels Of Paliperidone Extended-Release Tablets Are Not ...  -  May 23, 2007
Medical News Today (press release),Paliperidone may antagonize the effect of levodopa and other dopamine agonists. (1) Berwaerts J, Cleton A, et al. A randomized, open label, single center,

Schwarz Parkinson's patch ploughs on  -  May 10, 2007
LabTechnologist.com,Although the patch has been available in Europe for both early-stage Parkinson's and in combination with levodopa for advanced Parkinson's, the US approval

Diet, gout are related  -  May 15, 2007
Times Daily (subscription),For example, insulin, levodopa (for Parkinson's) aspirin, niacin (found in supplements and in the drug Advicor), excessive Vitamin A, cyclosporine (calms

Reno takes on Parkinson’s with curiosity  -  May 15, 2007
Wilkes Barre Times-Leader,A: I take Sinemet (a common medication with levodopa). I took Miraplex for a while but had to give it up. Q: I took Requip at first but had to stop because

Coenzyme Q­ 10 Doesn't Relieve Parkinson's Symptoms  -  May 14, 2007
MedPage Today,The patients were stratified at study outset according to levodopa treatment. The primary outcome was the change in the sum score of the UPDRS part II and

Treating restless leg syndrome  -  May 11, 2007
Cincinnati Post,An alternative drug treatment for patients unable to tolerate a dopamine agonist such as Requip is levodopa/carbidopa (Sinemet) 25/100.

FDA Approves SCHWARZ PHARMA's Neupro(R) (Rotigotine Transdermal ...  -  May 11, 2007
Medical News Today (press release),Rotigotine transdermal system is approved in Europe for the treatment of patients with early and advanced Parkinson's disease in combination with levodopa.

Whos funding innovation? Fox challenges biotech industry  -  May 9, 2007
DrugResearcher.com,..."Levodopa is the gold-standard treatment for Parkinson's, the disease I live with. Don't get me wrong, I love my meds... But it's a little frustrating that

Reno Is Taking On Her Disease  -  May 8, 2007
The Ledger,A. I take Sinemet (a common medication with levodopa). I took Miraplex for a while but had to give it up. Q. I took Requip at first but had to stop because

Reno took on illness with curiosity, not fear  -  May 8, 2007
Miami Herald,A: I take Sinemet (a common medication with levodopa). I took Miraplex for a while but had to give it up. Q:I took Requip at first but had to stop because

Challenges among BIO cheers  -  May 7, 2007
Newark Star Ledger,Fox said he takes the "gold standard" of treatment for Parkinson's disease, levodopa, which regulates dopamine levels. "It is a little frustrating that the

Lonnie Ali Champions 'Fight For MORE' Campaign  -  26 Apr 2007
Earthtimes.orgDoctors may recommend adding Zelapar to levodopa/carbidopa treatment when patients are experiencing a reduced response to this therapy.

Study Demonstrating Aeolus Compound’s Neuroprotection in Parkinson ...  -  26 Apr 2007
Business Wire (press release),The major therapeutic approach currently used to alleviate the symptoms of PD involves restoration of dopaminergic neurotransmission using levodopa,

Abbott pulls out of developing Orion's Simdax in the USA  -  26 Apr 2007
Pharma Times (subscription),Once again sales were driven by its Parkinson's disease drug Stalevo (carbidopa, levodopa and entacapone) - sold with partner Novartis - which increased 3%

Exhaustive Study to Expand the Efficacy of Drug L-dopa for Parkinson's  -  26 Apr 2007
MedIndia,Parkinson's sufferers are usually treated with the drug called levodopa or L-dopa that helps in reviving cellular communication. After prolonged use of the

Positive 'Restless Legs' Data Send XenoPort Shares Soaring  -  26 Apr 2007
BioWorld Online,The company also has in its pipeline XP21279, a prodrug of levodopa, for Parkinson's disease and XP20925, a prodrug of the aesthetic propofol.

A second lease of life  -  Apr 14, 2007
Financial Express,Introduced more than 30 years ago, Levodopa is the current gold standard for the diagnosis and treatment of Parkinson’s disease. “In PD, the degeneration of

Drug Reduces Daily "Off" Time For Parkinson Patients  -  Apr 10, 2007
Medical News Today (press release),The study involved 393 people with Parkinson disease who weren't responding optimally to the widely used treatment for Parkinson, levodopa.

24-Hour Parkinson’s Drug Cuts Symptoms  -  Apr 4, 2007
WebMDIn addition, people who took the 24-hour Requip were also able to reduce their daily dose of the widely used Parkinson’s drug levodopa, which is commonly

Drug Cuts 'Off' Time for Parkinson's Patients  -  Apr 5, 2007
Forbes,Half the patients took 24-hour prolonged release ropinirole and levodopa for six months, while the other half took a placebo and levodopa.

Ropinirole Prolonged-Release Reduces Parkinson's 'Off' Time  -  Apr 2, 2007
MedPage Today,This study suggests that it can help patients control motor symptoms longer, with lower daily doses of levodopa. Among 393 patients in the randomized study,

Rush University Medical Center To Conduct Phase III Clinical Trial ...  -  Apr 16, 2007
eMaxHealth.com,Although certain drugs, such as levodopa, can reduce the symptoms of Parkinson's disease, there are no proven treatments that can slow the progressive

24-Hour Parkinson's Drug: Longer Relief?  -  Apr 5, 2007
CBS News,...effects of the new 24-hour formulation of Requip in 393 people with Parkinson's disease who weren't responding well to levodopa alone.

Trial Of Creatine For Parkinson's Disease - Nutritional Supplement ...  -  Apr 13, 2007
Medical News Today (press release),The study will enroll people who have been diagnosed with PD within the past five years and who have been treated for two years or less with levodopa or

US regulatory boost for Skye  -  Apr 13, 2007
Hemscott,The results showed that adding REQUIP XL to Parkinson's patients' existing levodopa, or L-dopa, therapy significantly reduced 'off' time by an average of

ORION: Orion Group Interim Report 1-3/2007  -  Apr 25, 2007
Kauppalehti (press release),The combined net sales of Orion's proprietary products for Parkinson's Disease, Stalevo (levodopa, entacapone, carbidopa) and Comtess/Comtan (entacapone)

7 Companies Searching to Cure Parkinson's  -  Apr 25, 2007
Seeking Alpha,...a once-daily adjunct therapy for Parkinson’s disease patients being treated with levodopa/carbidopa. It has a forward P/E of 16.6 and a PEG of .8.

London shares outlook - higher, DJIA firmer, Iran eases rhetoric ...  -  Apr 2, 2007
Forbes,The company said combining the investigational extended release version of the drug with levodopa 'significantly reduced' off-time in patients.

Glaxo's Parkinson's Drug Delays Symptoms for Two Extra Hours  -  Apr 2, 2007
BloombergThe company-sponsored study found that adding a once-daily tablet of Requip XL 24-hour to standard levodopa therapy controlled tremors and involuntary body

Parkinson's patients desperate for help sign on to hole-in-the ...  -  Apr 22, 2007
San Francisco Chronicle,The herky jerky movements common to Parkinson's patients are a side effect of the drugs, usually levodopa. When the medicine is working, the muscles are

FDA Announces Voluntary Withdrawal of Pergolide Products  -  Apr 1, 2007
SolancoNews.com,Pergolide is in a class of medications called dopamine agonists and is used with levodopa and carbidopa to manage the symptoms (tremors and slowness of

Parkinson's sufferer, a cyclist, shares story in Mill Valley  -  Apr 25, 2007
Marin Independent-Journal,There is no proven cause of Parkinson's disease and no cure. Usually patients are treated with levodopa, which helps replace the brain's dopamine.

FDA Announces Withdrawal of Parkinson’s Drug from Market  -  Mar 30, 2007
Newsinferno.com,Pergolide is a dopamine agonist and is used in conjunction with levodopa and carbidopa to manage the symptoms (tremors, slowness of movement) of Parkinson’s

FDA Announces Voluntary Withdrawal of Pergolide Products  -  Mar 29, 2007
DG NewsPergolide is in a class of medications called dopamine agonists and is used with levodopa and carbidopa to manage the symptoms of Parkinson's disease.

NIH Announces Phase III Clinical Trial Of Creatine For Parkinson's ...  -  Mar 28, 2007
Medical News Today (press release),Although certain drugs, such as levodopa, can reduce the symptoms of PD, there are no proven treatments that can slow the progressive deterioration in

Global Study To Extend Effectiveness Of Drug For Parkinson's  -  Apr 24, 2007
Medical News Today (press release),After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that controls

GlaxoSmithKline: Ropinirole improves Parkinson's symptoms  -  Apr 2, 2007
MarketWatchThe pharmaceutical company said the medicine, when added to patients' existing levodopa therapy, reduced 'off' time by more than two hours a day,

Parkinson's disease better controlled with prolonged-release drug  -  Apr 2, 2007
Therapeutics Daily (subscription) (press release),...a safe and effective treatment for patients with Parkinson's disease suboptimally controlled with levodopa, according to the results of phase III trial.

SCHWARZ PHARMA Announces Publication Of Rotigotine Data For ...  -  Apr 20, 2007
Medical News Today (press release),Rotigotine transdermal system was added to stable levodopa treatment. Compared to placebo, both rotigotine 8 mg/24 hr and 12 mg/24 hr significantly reduced

FDA announces withdrawal of Parkinson's drug  -  Mar 29, 2007
Indianapolis Star,Pergolide is in a class of medications called dopamine agonists and is used with levodopa and carbidopa to manage the symptoms - tremors and slowness of

IU to test possible Parkinson's treatment  -  Mar 28, 2007
South Bend Tribune,Eligible are people diagnosed with Parkinson's within the past five years who have been treated for two years or less with levodopa or other drugs that

Janet Reno takes on Parkinson's with curiosity, not fear  -  Apr 23, 2007
Orange County Register,A: I take Sinemet (a common medication with levodopa). I took Miraplex for a while but had to give it up. Q: I took Requip at first but had to stop because

SkyePharma PLC - Once-Daily REQUIP LP Extended-Release Tablets ...  -  Apr 23, 2007
PharmaLive.com (press release),One study was a ropinirole monotherapy study in early PD, and the other was an adjunct study with levodopa (L-dopa) in advanced PD.

Once daily, extended-release ropinirole improves Parkinson’s ...  -  Apr 3, 2007
WebWire (press release),Adding the once daily, investigational medication REQUIP® (ropinirole HCl) XL 24-Hour™ Extended-Release Tablets to Parkinson’s patients’ existing levodopa

Once Daily, Extended-Release Ropinirole Improves Parkinson's ...  -  Apr 3, 2007
PharmaLive.com (press release),...investigational medication REQUIP(R) (ropinirole HCl) XL 24-Hour(TM) Extended-Release Tablets to Parkinson's patients' existing levodopa (L-dopa)

London shares outlook - higher, DJIA firmer, Iran eases rhetoric ...  -  Apr 2, 2007
Euro2day,The company said combining the investigational extended release version of the drug with levodopa "significantly reduced" off-time in patients.

Doctors attack gambling policies  -  Apr 19, 2007
BBC News,..."Many people with Parkinson's in the UK are prescribed dopamine agonists, often in conjunction with another drug levodopa, as their standard therapy.

Parkinson's Drugs Undergoing Tests  -  Apr 18, 2007
Science Daily (press release)Science Daily — After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication

Jefferson participating in global study to extend effectiveness of ...  -  Apr 18, 2007
EurekAlert (press release),PHILADELPHIA— After Parkinson's disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication

New Global Study to Extend Effectiveness of Drug for Parkinson’s  -  Apr 18, 2007
Newswise (press release)Newswise — After Parkinson’s disease patients use the drug levodopa or L-dopa for several years as a treatment for restoring the cellular communication that

Rotigotine Study To Investigate 24-hour Action And Sleep Benefits ...  -  Apr 14, 2007
Medical News Today (press release),The drug is approved both as monotherapy for patients with early-stage Parkinson's disease and in combination with levodopa for the treatment of patients

Using a Diary Card to Manage Parkinson's Disease Symptoms  -  Feb 16, 2007
PharmaLive.com (press release),Like many people with PD, Gordon started treatment with a traditional levodopa medication. However, Gordon found that after several years, her symptoms

NeuroDerm's Transdermal L-DOPA Parkinson's Patch Completes First ...  -  Feb 1, 2007
PipelineReview.com (press release),The main objective of this GCP compliant pilot study was to assess the pharmacokinetic profile of levodopa in the blood of healthy volunteers following

Rotigotine Patch (Neupro)  -  Feb 12, 2007
Business Portal 24 (press release),...in combination with levodopa through the course of Parkinson's disease (PD) to the late stages when the therapeutic efficacy of levodopa may fluctuate.

TRx Pharma introduces FOLMOR for treatment of cardiovascular disease  -  Feb 7, 2007
Carolina Newswire (press release),FOLMOR should not be given to patients taking levodopa, as the B6 vitamin antagonizes the action of levodopa. FOLMOR can be given to patients taking both

Multidisciplinary Expert Panel Highlights Boehringer Ingelheim´s ...  -  Feb 11, 2007
Medical News Today (press release),...of the dopamine deficiency in the PD striatum, symptomatic treatment focused on addressing this problem with the use of the dopamine precursor levodopa.

Orion Oyj: Bulletin of orion corporation financial statements for ...  -  Feb 6, 2007
Kauppalehti (press release),In the study, Stalevo is compared with conventional levodopa/carbidopa medication. The study, under way since late 2004, is being carried out in

Portion of Orion profits may go towards new Simdax study  -  Feb 7, 2007
Pharma Times (subscription),Once again sales were driven by its Parkinson's disease drug Stalevo (carbidopa, levodopa and entacapone) - sold with partner Novartis - which increased

Parkinson's Therapeutics Reviewed by NeuroInvestment  -  Feb 5, 2007
Market Wire (press release)While the initial treatment of Parkinson's with levodopa is a relative success story for neurology, the fact is that current treatments for Parkinson's are

Gambling problem can affect restless legs patients  -  Jan 31, 2007
Scientific AmericanSome of these drugs commonly used for one or both conditions include Requip (generic name ropinirole), Mirapex (pramipexole) and Sinemet (levodopa plus

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