Recent news on Losartan

Zentiva: 13% sales growth in Poland in Q1  -  May 24, 2007
Polish Market,Important contributions to sales were also made by the recently introduced urology drug Fokusin (tamsulosin), the cardiovascular drug Lozap (losartan) and

New Data Highlights Potential of SPP100 (Tekturna) as Gold ...  -  May 21, 2007
PharmaLive.com (press release),The study also showed that 150mg and 300mg SPP100 once daily were comparable to Losartan 100mg, which is double the usual starting dose of this ARB (Stanton

Dr. Reddy’s FY07 Revenue at Rs. 65095 Million (US$ 1.5 Billion ...  -  May 18, 2007
Business Wire (press release),...by 47% to Rs. 2.1 billion in FY07 from Rs. 1.4 billion in FY06 primarily led by growth of key products of sertraline, finastride, losartan and ramipril.

Ann Reinking to Be Honored at National Marfan Foundation Benefit ...  -  26 Apr 2007
WM Experts (press release),However, breakthrough research in the past year has identified a commonly prescribed blood pressure medicine, losartan (Cozaar), that prevents and may even

Zydus receives tentative approval for Losartan Potassium tablets  -  Apr 20, 2007
Equity Bulls,Cadila Healthcare Ltd has announced that the Company has received tentative approval for Losartan Potassium Tablets in the strengths of 25 mg,

Merck's Q1 profit rises  -  Apr 20, 2007
Pharma Times (subscription),Also helping Merck obtain double-digit earnings were the angiotensin receptor blockers, Cozaar (losartan) and Hyzaar (losartan plus hydrochlorothiazide),

Cadila gets tentative FDA approval for generic Cozaar tablets for ...  -  Apr 20, 2007
Hemscott,...from the US Food and Drug Administration to market its generic version of Merck & Co Inc's antihypertensive agent Cozaar (losartan potassium) tablets.

Couple searches for hope for ailing daughter  -  Mar 31, 2007
DesMoinesRegister.com,He explains that the drug, losartan, is a widely used blood-pressure medication that has been proven to be safe. Researchers found that it interferes with

Doctor To Speak About Latest Marfan Syndrome Research  -  Mar 30, 2007
KCCI.com,She now is beginning a new drug trial using a commonly prescribed blood pressure medicine Losartan discovered by a team of researchers at Johns Hopkins

Uniform drug pricing fails to help consumers  -  Mar 30, 2007
Times of India,In case of Ranbaxy's Storvas (atorvastatin) the price has increased from Rs 80 to 84.84 ie by 6%, and Covance-50 (losartan) by over 20% to Rs 60.45.

No Benefit of PCI Over Optimal Drugs for Preventing Events in ...  -  Mar 30, 2007
Medscape (subscription)...amlodipine, and isosorbide mononitrate, alone or in combination, along with either lisinopril or losartan as standard secondary prevention.

Common blood pressure drug reduces progressive muscle degeneration ...  -  Feb 6, 2007
Hindu,When the researchers gave the mice losartan to inhibit TGF-beta, they showed that the muscle was able to regenerate and repair much more efficiently.

Common Blood Pressure Drug Reduces Progressive Muscle Degeneration ...  -  Feb 6, 2007
Medical News Today (press release),The research is based on similarities in the mechanism of DMD and another rare disease -Marfan syndrome - and the discovery that losartan is effective in

Common Blood Pressure Drug Treats Muscular Dystrophy in Mice  -  Feb 5, 2007
Johns Hopkins Gazette,In 2006, a team led by Harry "Hal" Dietz discovered that treating Marfan mice with losartan (Cozaar) dramatically strengthens the aorta, the major artery

Common blood pressure drug improves muscle regeneration in mice  -  Feb 4, 2007
Zee News,London, Feb 04: A collaborative research conducted by US researchers has found that the commonly prescribed blood pressure medication losartan to be

Common blood pressure drug improves muscle regeneration in mice  -  Feb 3, 2007
DailyIndia.com,3 (ANI): A collaborative research conducted by US researchers has found that the commonly prescribed blood pressure medication losartan to be effective in

Pharmacopeia tout 2-for-1 cardiovascular drug  -  Feb 19, 2007
DrugResearcher.com,Other than Avapro, other angiotensin II receptor blockers currently approved are Diovan (valsartan) from Novartis and Cozaar (losartan) from Merck & Co.

Bringing light to Marfan  -  Feb 8, 2007
Lexington Minuteman,On the research front, a large clinical trial is about to get underway to determine if an existing drug call Losartan can slow or halt the formation of

UK could save a billion on cholesterol and blood pressure drugs ...  -  18 Jan 2007
innovations report,...“In this study the generic drug simvastastin replaced low dose atorvastastin for high cholesterol treatment and candesartan replaced losartan for treating

Enzyme Replacement in Fabry Disease: The Essence Is in the Kidney  -  Jan 16, 2007
Annals of Internal MedicineEffects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med. 2001;345:861-9. [PMID: 11565518].

Left Ventricular Hypertrophy Regression and Atrial Fibrillation ...  -  Jan 2, 2007
Journal of American Medical Association (subscription),In both the main LIFE study 2 and the echocardiographic substudy, 3 greater regression of LVH in losartan-treated patients compared with atenolol-treated

Health providers could save billions without compromising ...  -  Jan 17, 2007
PressZoom (press release),..."In this study the generic drug simvastastin replaced low dose atorvastastin for high cholesterol treatment and candesartan replaced losartan for treating

Low libido from blood pressure drug?  -  Jan 16, 2007
Newsday,Some physicians report that ACE inhibitors (such as enalapril or lisinopril) or ARBs (such as losartan or valsartan) may be less likely to affect sexual

Pancreatic Cancer Spread Could Be Halted By Blood Pressure Drugs  -  Dec 11, 2006
Medical News Today (press release),They also looked at the effects of blood pressure drugs captopril, an ACE inhibitor, and losartan, an AT1R blocker, on VEGF production in cancer cell lines.

Merck & Co keeps profit forecasts conservative for 2007  -  Dec 7, 2006
Pharma Times (subscription),...$3.1-$3.4 billion for the antihypertensive Cozaar/Hyzaar (losartan); and $2.6-$2.9 billion for the osteoporosis drug Fosamax (alendronate).

Speedel Holding AG Announces Up to 3 Month Extension of US ...  -  Dec 14, 2006
PharmaLive.com (press release),The study also showed that 150mg and 300mg SPP100 once daily were comparable to Losartan 100mg, which is double the starting dose of this ARB (Stanton,

Severe interaction between low-dose ritonavir and a blood pressure ...  -  Dec 11, 2006
Aidsmap,A week later modified blood pressure therapy consisting of nifedipine 30mg twice daily, enalapril 5mg twice daily and losartan 5mg twice daily was initiated

ACNP: Hypertension Drugs May Block Alzheimer's  -  Dec 6, 2006
Psychiatric Times,Dr. Pasinetti presented data on three of the drugs -- propranolol (sold under various brand names), Cardene (nicardapine), and Cozaar (losartan) -- that

Mechanical 'Artificial Hearts' Can Return Heart To Normal And ...  Nov 5, 2006
The drugs used were lisinopril, carvedilol, spironolactone and losartan in the first stage of treatment and bisoprolol and clenbuterol in the second. ... -Medical News Today (press release), drugs to be cheaper from tomorrow  Oct 31, 2006
Diclofenac, paracetamol, chloroquine, Albendazole, Ampicilin, Amoxycilin, Cephalexin, Ciprofloxacin, Amlodipine, Atenolol, Enalapril, Losartan, Nifedipine etc. ... -Moneycontrol.com, From the brink of death to a normal life: Can LVADs plus drug ...  Nov 1, 2006
...drugs intended to enhance reverse remodeling—lisinopril to 40 mg daily, carvedilol to 50 mg twice daily, spironolactone to 25 mg daily, and losartan to 100 ... -TheHeart.Org, Mechanical Assist Plus Potent Medical Therapy Revives Failing ...  Nov 1, 2006
Patients were given a combination of combination of Zestril (lisinopril), Coreg (carvedilol), Aldactone (spironolactone) and Cozaar (losartan) to reverse ... -MedPage Today, Speedel Begins Phase IIa Trial With Next Generation Renin ...  Oct 30, 2006
The study also showed that 150mg and 300mg SPP100 once daily were comparable to Losartan 100mg, which is double the starting dose of this ARB (Stanton, Jensen ... -PrimeZone (press release), Left Ventricular Assist Device and Drug Therapy for the Reversal ...  Nov 1, 2006
The patients underwent implantation of left ventricular assist devices and were treated with lisinopril, carvedilol, spironolactone, and losartan to enhance ... -New England Journal of Medicine (subscription), Highlights from EASD 2006: Targeting CV risks in dysglycemic ...  Oct 12, 2006
In patients with type 2 diabetes the angiotensin-receptor blockers (ARBs) irbesartan (the IDNT study) and losartan (the RENAAL study) prevented progression of ... -TheHeart.Org, Research and Markets: Examine Financial Performance of Merck & Co ...  Oct 9, 2006
Cozaar (losartan potassium) was the first angiotensin-II receptor antagonist selective for AT1 receptors to be developed for the treatment of hypertension. ... -Genetic Engineering News (press release), preventing enlarged heart lowers risk of atrial fibrillation in ...  Sep 12, 2006
All patients in the LIFE study received Losartan- or atenolol-based therapies. In a previous LIFE study paper (Circulation, 2003 ... -South Asian Women's Forum

For High Blood Pressure Patients, Preventing Enlarged Heart ...  Sep 13, 2006
Both studies used data from the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) study conducted between 1995 and 2001. ... -DG News

Old Drug Could Fix Hearts  Sep 14, 2006
He was 35 years old. Scientists believe that a common hypertension drug called losartan could have saved him. ... "Losartan is really equivalent to a smart bomb. ... -Wired News

Regression of Electrocardiographic Left Ventricular Hypertrophy ...  Sep 12, 2006
...duration product or Sokolow-Lyon voltage, with no history of AF, without AF on the baseline electrocardiogram, and enrolled in the Losartan Intervention for ... -Journal of American Medical Association (subscription)

ASNC: Dazzling Array of Imaging Modalities Require Sober Approach  Sep 15, 2006
...his 30s. The patient was taking aspirin 81 mg/day, Cozaar (losartan) at 50 mg, and Zocor (simvastatin)at 20 mg/day. The investigators ... -MedPage Today

EUROPEAN COMMISSION GRANTS APPROVAL FOR ADDING HIGH DOSE COAPROVEL ...  Sep 5, 2006
Time course and extent of angiotensin II antagonism after irbesartan, losartan, and valsartan in humans assessed by angiotensin II dose response and ... -ITNews

Regression of LVH in hypertensives reduces risk of AF independent ...  Sep 14, 2006
A prior analysis of the LIFE study has shown that losartan treatment reduced the risk of developing AF compared with atenolol, as reported by heartwire, Okin ... -TheHeart.Org

Canadian Web Sites Selling Counterfeit Drug Products  Sep 1, 2006
Lipitor (atorvastatin calcium), Diovan (valsartan), Actonel (risedronate sodium), Nexium (esomeprazole), Hyzaar (losartan potassium/ hydrochlorothiazide), Zetia ... -Facts and Comparisons

SPP100 (Rasilez): Pooled Data Analysis Confirms Efficacy And ...  Sep 5, 2006
The study also showed that 150mg and 300mg SPP100 once daily were comparable to Losartan 100mg, which is double the starting dose of this ARB (Stanton, Jensen ... -Medical News Today

Pancreatic Cancer Spread Could Be Halted By Blood Pressure Drugs  -  12 Dec 2006
Medical News Today (press release),They also looked at the effects of blood pressure drugs captopril, an ACE inhibitor, and losartan, an AT1R blocker, on VEGF production in cancer cell lines.

Merck & Co keeps profit forecasts conservative for 2007  -  Dec 7, 2006
Pharma Times (subscription),...$3.1-$3.4 billion for the antihypertensive Cozaar/Hyzaar (losartan); and $2.6-$2.9 billion for the osteoporosis drug Fosamax (alendronate).

Severe interaction between low-dose ritonavir and a blood pressure ...  -  Dec 11, 2006
Aidsmap,A week later modified blood pressure therapy consisting of nifedipine 30mg twice daily, enalapril 5mg twice daily and losartan 5mg twice daily was initiated

Reports from Wake Forest University, US, add new data to knowledge ...  -  Nov 23, 2006
Therapeutics Daily (subscription) (press release),Study 1: In patients with diastolic dysfunction and hypertensive responses to exercise, 6 months of losartan and hydrochlorothiazide (HCTZ) blunted systolic

Obesity Mutes Favorable Impact of Anti-Hypertension Drug on ...  -  Nov 16, 2006
DG NewsDr. Gerdts and colleagues scrutinized the results of the Losartan Intervention for Endpoint Reduction in Hypertension (LIFE) trial, specifically trying to

ACNP: Hypertension Drugs May Block Alzheimer's  -  Dec 6, 2006
Psychiatric Times,Dr. Pasinetti presented data on three of the drugs -- propranolol (sold under various brand names), Cardene (nicardapine), and Cozaar (losartan) -- that

Antihypertensives: Generics striking at heart of the market  -  Nov 16, 2006
Pharmaceutical Business Review...s Cozaar (losartan) in Spain in 2007. In the US, Cozaar will lose protection in 2010. This event has the potential to not only dramatically affect the

Antihypertensives: Generics Striking at Heart of the Market Under  -  Nov 16, 2006
PharmaLive.com (press release),The first Angiotensin Receptor Blocker (ARB) to lose patent protection will be Merck’s Cozaar (losartan) in Spain in 2007. In the US, Cozaar will lose

Loeys-Dietz syndrome: Similar to but more lethal than Marfan's  Aug 24, 2006
According to Dietz, a large National Institutes of Health-sponsored clinical trial is getting under way to explore the use of losartan, an angiotensin-2 ... -TheHeart.Org

New, Deadly Relative of Marfan's Syndrome Discovered  Aug 23, 2006
While there is no drug treatment currently for Marfan's syndrome or Loeys-Dietz syndrome, research at Hopkins has raised hopes about losartan, a drug used to ... -Forbes

Grapefruit-Drug Interactions  Aug 15, 2006
Effect of grapefruit juice on the pharmacokinetics of losartan and its active metabolite E3174 in healthy volunteers. Ther Drug Monit 2001;23:369-73. 19. ... -American Family Physician

Denenberg: When It Comes To Prescription Drugs, Know Who To Trust  Aug 17, 2006
Some of the ARB inhibitors are olmesartan (Benicar) and losartan (Cozaar)(the generic version of these drugs ends with "sartan"). ... -Evening Bulletin

Diverse challenges await generics industry  Aug 7, 2006
...in this period: Pfizer's Norvasc (amlodipine), Lipitor (atorvastatin) and Viagra (sildenafil), Merck's Zetia (ezetimibe) and Cozaar (losartan), GSK's Avandia ... -PipelineReview.com

Updating European Guidelines for the Management of Hypertension  Jul 17, 2006
Several studies, including the Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) study, [8] have shown that regression of left ventricular ... -Medscape (subscription)

Treating heart failure  Jul 8, 2006
Examples of useful ARBs for heart failure which have been shown to be beneficial in some patients include valsartan, candesartan, and losartan. ... -Malaysia Star

Teen with Marfan syndrome inspired by Mom  Jul 13, 2006
...of the National Marfan Foundation, the foundation has published new information this past spring about an improved and approved medication called Losartan. ... -Lawrence Ledger

Generic pie to grow bigger but also carved up into smaller pieces  Jul 10, 2006
...this period: Pfizer's Norvasc (amlodipine), Lipitor (atorvastatin) and Viagra (sildenafil), Merck's Zetia (ezetimibe) and Cozaar (losartan), GlaxoSmithKline 's ... -In-PharmaTechnologist.com

Diverse challenges await generics industry  Jul 7, 2006
...in this period: Pfizer's Norvasc (amlodipine), Lipitor (atorvastatin) and Viagra (sildenafil), Merck's Zetia (ezetimibe) and Cozaar (losartan), GSK's Avandia ... -Pharmaceutical Business Review

Teva's stock wounded in ongoing drug wars  Jun 22, 2006
...appealed successfully. It also won tentative approval for two sizes of Losartan potassium and hydrochlorothiazide tablets. Final ... -MSN Money



New Phase III Data on Renin Inhibitor SPP100 (Rasilez) in ...  16 May 2006
The study also showed that 150mg and 300mg SPP100 once daily were comparable to Losartan 100mg, which is double the starting dose of this ARB (Stanton, Jensen ... - Yahoo! News

Losartan prevents progression of Marfan syndrome in mice  Apr 28, 2006
Treatment with losartan (Cozaar), a blood pressure medication, can prevent the progression of Marfan syndrome, a connective tissue disorder, in mice, according ... - About - News & Issues

Blood Pressure Med Prevents Aortic Aneurysm in Mice with Marfan  May 1, 2006
Scientists at Johns Hopkins have used a commonly prescribed blood pressure medicine, losartan (Cozaar), to prevent a potentially fatal weakening of arteries in ... - Johns Hopkins Gazette

Zentiva NV 1st Quarter Results 2006  May 2, 2006
Out of our key promoted brands good sales growth was achieved by the hypnotic drug Hypnogen (zolpidem), the anti-hypertensive product Lozap (losartan) and the ... - PharmaLive.com

Drug Shows Promise for Marfan Syndrome  May 2, 2006
A team of scientists at Johns Hopkins University has found that treatment with losartan prevented the development of aortic aneurysm and other defects in a ... - Journal of American Medical Association (subscription)

Banyu Pharmaceutical Obtains Additional Approval for NU-LOTAN ...  Apr 24, 2006
Tokyo, Apr 24, 2006 (JCN) - Banyu Pharmaceutical has obtained additional approval for NU-LOTAN Tablet 25mg/ 50mg (losartan potassium), its proprietary agent ... - Japan Corporate News

Diabetes And Kidney  May 9, 2006
...inhibitors (ACE inhibitors such as enalapril, ramipril, lisinopril, etc.) or angiotensin receptor blockers (ARBS such as losartan, irbesartan, telmisartan, etc ... - Newindpress (subscription)

Merck Q1 profits rise despite flat revenues  Apr 21, 2006
High blood pressure treatments Cozaar (losartan) and Hyzaar (losartan and hydrochlorothiazide) slipped 2% to $701 million, while osteoporosis drug Fosamax ... - Pharma Times (subscription)

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