Recent news on Memantine

Bipolar Depression Focus Of Research Study - Indiana University ...  -  25 May 2007
Medical News Today (press release),The study will evaluate the effectiveness of Memantine (nameneda) in the treatment of bipolar depression. Participants who qualify for the study must have

Market Report -- In Play (NTII)  -  May 2, 2007
MSN MoneyNeurobiological Tech. reports $1.9 mln quarterly payment for sales of Memantine Co announces it has received approx $1900000 from Merz Pharmaceuticals GmbH

NTI gets $1.9 million royalty payment  -  May 2, 2007
East Bay Business Times,...a royalty payment of approximately $1.9 million from Merz Pharmaceuticals GmbH for sales of the drug Memantine for the treatment of Alzheimer's disease.

PCI trio tackles ALS  -  May 2, 2007
St. Thomas Times-Journal,The trio researched whether an Alzheimer drug called Memantine could be used to treat another neurological disorder, amyotrophic lateral sclerosis.

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce ...  -  May 23, 2007
PharmaLive.com (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Pharma tells Parliament about the problems with NICE  -  May 21, 2007
Pharma Times (subscription),...the condition - Pfizer/Eisai's Aricept (donepezil), Novartis' Exelon (rivastigmine), Shire's Reminyl (galantamine) and Lundbeck's Ebixa (memantine).

Alzheimer's Treatments and Medications  -  May 19, 2007
HealthCentral.com,...appeared to help improve memory and daily living ability in patients with moderate-to-severe Alzheimer's when taken in combination with memantine.

Drugs 'have Alzheimer's benefits'  -  May 14, 2007
Channel 4 News,It also ruled that memantine should be used only in clinical studies for people with moderately severe to severe Alzheimer's.

Earnings shoot up at Denmark's Lundbeck as Lexapro sales soar  -  May 10, 2007
Pharma Times (subscription),The Alzheimer's disease drug Ebixa (memantine) climbed 26% to 391 million kroner and two of the firm's newer products - Azilect (rasagiline) for Parkinson's

From the analyst's couch: Therapies for Alzheimer's disease  -  May 4, 2007
Nature.com (subscription),...and the N-methyl-D-aspartate (NMDA)-receptor modulator memantine (Namenda; Forest/Lundbeck) — are approved for the treatment of symptoms of AD.

Response Submitted to FDA Approvable Letter for Hypertension ...  -  May 2, 2007
PipelineReview.com (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Postcode lottery  -  Apr 16, 2007
Evening Telegraph,The drug Memantine is not recommended for general use by NHS Scotland but in exceptional cases a consultant can prescribe the drug.

Forest Laboratories, Inc. Reports Fiscal Year 2007 Fourth Quarter ...  -  Apr 24, 2007
PR-Inside.com (Pressemitteilung),...desmoteplase for the treatment of acute ischemic stroke, and memantine MR for the treatment of moderate to severe Alzheimer's disease.

Treating Alzheimer's Disease  -  Apr 12, 2007
Market-Day.net,A new medication, memantine (Namenda), may be used alone or withcholinesterase inhibitors to treat moderate to severe symptoms of confusionand memory loss

Evotec and Boehringer Ingelheim Enter into Target Discovery ...  -  Apr 3, 2007
Oxfordshire Bioscience Network (press release),Aided by a growing elderly population, the introduction of the first drug approved for moderate-to-severe AD, ‘memantine’, has led to a compound annual

Alzheimer's drug could help my wife  -  Apr 4, 2007
Therapeutics Daily (subscription) (press release),But a drug called Memantine, or Ebixa, can temporarily slow down the progression of symptoms. Mr Welling said that the cost of a year's worth of the drug

Please let my wife have drug  -  Apr 4, 2007
Therapeutics Daily (subscription) (press release),Bryan Welling, of St George, says memantine, or Ebixa, costs £2.50 a day - and that the cost of prescribing it for a whole year is less than just a week of

Dutton Associates Announces Investment Opinion: Neurobiological ...  -  Apr 23, 2007
PharmaLive.com (press release),In addition, the Company benefits from an increasing stream of royalties related to sales of Memantine(TM) for the treatment of Alzheimer's disease.

Dutton Associates Announces Investment Opinion: Neurobiological ...  -  Apr 23, 2007
Business Wire (press release),In addition, the Company benefits from an increasing stream of royalties related to sales of Memantine™ for the treatment of Alzheimer’s disease.

Dementia causes are easier to pinpoint  -  Apr 23, 2007
Mail Tribune,For people who already have moderate to severe memory loss and thinking problems, physicians may prescribe memantine, a drug that shows promise for slowing

Forest Laboratories, Inc. Sets Date and Conference Call for Fiscal ...  -  Apr 12, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Barriers to the Appropriate Clinical Use of Medications That ...  -  Apr 5, 2007
Psychiatric Services (subscription)Livingston G, Katona C: The place of memantine in the treatment of Alzheimer's disease: a number needed to treat analysis.

Neurobiological Technologies Receives $1.7 Million Quarterly ...  -  Jan 31, 2007
Drug Newswire (press release),Under an exclusive marketing agreement, NTI receives quarterly royalty payments on sales of Memantine by Merz and its marketing partners.

Prescribing Trends in Alzheimer’s Disease Indicate Neurologists ...  -  Feb 2, 2007
PharmaLive.com (press release),The survey also found that 12% of mild severity pharmacologically treated AD patients are prescribed memantine in the seven major markets.

Alzheimer's disease: physicians do not always practice what NICE ...  -  Feb 5, 2007
Pharmaceutical Business ReviewIn addition, Datamonitor found that 2.2 times more AD patients receive AChEI + memantine combination therapy than memantine monotherapy in the UK.

Neurobiological Technologies, Inc Reports Second Quarter Results  -  Feb 9, 2007
PharmaLive.com (press release),...$1.7 million from royalty fees from the commercial sales of Memantine by our marketing partners in the United States and certain European countries,

Allergan Reports Fourth Quarter Operating Results  -  Jan 31, 2007
Genetic Engineering News (press release),Following the fourth quarter, Allergan completed the initial analysis of the data from the first of two phase III clinical trials of memantine for the

Market Report -- In Play (NTII)  -  Jan 31, 2007
MSN MoneyNeurobiological Tech says receives $1.7 mln quarterly payment for sales of memantine Co announces it has received approximately $1708000 from Merz

Neurobiological Technologies gets $1.7M royalty  -  Jan 31, 2007
East Bay Business Times,Technologies Inc. said Wednesday that Merz Pharmaceuticals GmbH paid it $1.7 million as a royalty on sales of the Alzheimer's drug Memantine.

Forest Laboratories Announces Rule 144 Sale by Executive Officer  -  Feb 15, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Volunteers Sought to Study Medication That May Block Progression ...  -  Feb 14, 2007
Saint Louis University,They may continue to take medications already prescribed to treat their Alzheimer's disease, such as acetylcholinesterase inhibitors and memantine.

Plane Crash Kills Renowned Alzheimer's Researcher  -  Feb 6, 2007
Associated Content,Those drugs are Tacrine (Cognex), donepezil (Aricept), rivastigmine (Exelon), galantamine (Razadyne), and memantine (Namenda).

Over 300 Different Compounds Are at Various Stages of Development ...  -  Feb 5, 2007
PharmaLive.com (press release),Currently the only approved neuroprotective therapy in is memantine. Management of these patients also require neuroleptics for aggressive behavior and

(PRN) - Stoneridge Reports Fourth-Quarter and Full-Year 2006 ...  -  Jan 31, 2007
Bolsamania.com,...(PRN) - Neurobiological Technologies Receives $1.7 Million Quarterly Payment for Sales of Memantine ... [+]. (PRN) - Prince George's County, Maryland,

Dawson James Securities Initiates Research Coverage on ...  -  Jan 30, 2007
PR Newswire (press release),XERECEPT(R) representing the lower risk/lower reward drug with Neurobiological Technologies Memantine royalty stream providing some downside protection,

Lexapro and Namenda push Forest Labs earnings up 28  -  Jan 17, 2007
Pharma Times (subscription),...with sales of Lexapro (escitalopram) climbing 14% to $545.9 million, while Namenda (memantine) enjoyed a 40% increase to $173.9 million.

Forest Laboratories, Inc. Reports Q3'07 Diluted Earnings Per Share ...  -  Jan 16, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Alzheimer's disease: What you need to know?  -  Jan 15, 2007
Food Consumer,Memantine, also known by its brand name Namenda®, is approved for use in moderate to severe forms of the disease. Photo of Alzheimer's disease research lab.

Forest Laboratories Announces Completion of Acquisition of Cerexa ...  -  Jan 12, 2007
PharmaLive.com (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Full Text  -  Jan 11, 2007
Science Magazine (subscription)They argue that compounds such as Forest's drug Namenda (memantine HCl), approved in 2003 for the treatment of Alzheimer's, and ImClone's Erbitux,

INC Research appoints Hans Moebius as Senior VP of CNS Division  -  Jan 10, 2007
Carolina Newswire (press release),...up the team that won the German Industry Innovation Award for the international development of memantine in late-stage Alzheimer’s disease (2002).

Catatonic Coma With Profound Bradycardia  -  Jan 5, 2007
Psychosomatics (subscription)Thomas C, Carroll BT, Maley RT, et al: Memantine and catatonic schizophrenia. Am J Psychiatry 2005; 162:626 [Free Full Text]. Fricchione GL: Brain evolution

Cerexa to Be Acquired by Forest Laboratories for $480 Million Plus ...  -  Dec 14, 2006
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Plasma Cortisol and Progression of Dementia in Subjects With ...  -  Dec 6, 2006
Am J Psychiatry (subscription)Miguel-Hidalgo JJ, Alvarez XA, Cacabelos R, Quack G: Neuroprotection by memantine against neurodegeneration induced by ß-amyloid (1-40).

Memantine Can Provide Behavioural Mood and Psychosis Benefits in ...  Sep 22, 2006
PARIS, FRANCE -- September 22, 2006 -- Memantine shows statistically significant benefits over placebo for total behavioural symptoms in patients with moderate ... -DG News

Memantine Improves Behavioural Symptoms in Patients With Moderate ...  Sep 7, 2006
GLASGOW, UK -- September 6, 2006 -- The specific, uncompetitive N-methyl-D-aspartic acid (NMDA) receptor antagonist memantine is effective in treating and ... -DG News

Robbing lives, one day at a time  Sep 23, 2006
The second class contains only one form of drug called memantine that blocks the receptors of the neurotransmitter glutamate in the brain. ... -Fremont Tribune

Pfizer and TransTech enter deal that’s all the RAGE  Sep 21, 2006
Cholinesterase inhibitors including donepezil (Aricept), galantamine (Reminyl) and rivastigmine (Exelon) and NMDA receptor antagonists, such as memantine (Ebixa ... -LabTechnologist.com

Study suggests a second dimension to Alzheimer's disease  Sep 10, 2006
Indeed, he added, a drug called memantine, which is already in use against Alzheimer's, acts on receptors that are a component of the calcium pathway. ... -Hindu

Forest Laboratories Inc. Announces Appointment of Dr. Lawrence S. ...  Sep 7, 2006
...for adults for the initial and maintenance treatment of major depressive disorder and for generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl ... -PR Newswire

Allergan: memantine could become first-line combination glaucoma ...  -  Nov 16, 2006
Pharmaceutical Business ReviewBy Staff Writer. Allergan's memantine could offer a novel mechanism to slow glaucoma progression if the current phase III trial shows positive data. ...

Experts Support The Continual Prescribing Of Ebixa (memantine) For ...  -  Nov 22, 2006
Medical News Today (press release),Lundbeck is disappointed by today's guidance on the use of drugs to treat AD where NICE has recommended Ebixa (memantine) only "as part of clinical studies for ...

Lexapro(R) Demonstrated Significance On Prospectively Defined ...  -  Dec 7, 2006
Medical News Today (press release),...indicated for adults for the internal and maintenance treatment of major depressive disorder and generalized anxiety disorder; Namenda(R) (memantine HCl), an N ...

Plasma Cortisol and Progression of Dementia in Subjects With ...  -  Dec 6, 2006
Am J Psychiatry (subscription)Miguel-Hidalgo JJ, Alvarez XA, Cacabelos R, Quack G: Neuroprotection by memantine against neurodegeneration induced by ß-amyloid (1-40). ...

Challenge to dementia drug ruling  -  Nov 16, 2006
Guardian Unlimited,Another drug, Ebixa (memantine), is only to be used in clinical studies for people with moderately severe to severe Alzheimer's disease. ...

Call for improved dementia care  -  Nov 21, 2006
BBC News,A fourth drug, memantine (Ebixa), is to be used only in clinical studies of people with moderately severe to severe Alzheimer's disease. ...

Storm as drugs watchdog refuses to reveal why it denied ...  -  Nov 17, 2006
Daily Mail - UK,...rivastigmine). Another drug, Ebixa (memantine), which improves severe behavioural problems is only to be used in clinical studies. ...

'Disgraceful' ruling sparks angry protest  -  Nov 17, 2006
ic CheshireOnline,The Alzheimer's Society last month failed to overturn NICE proposals on dementia drugs donepezil, reminyl, memantine and exelon. ...

Campaign attacks health watchdog  -  Nov 21, 2006
Yorkshire Post Today,Exelon (rivastigmine) on the NHS. Another drug, Ebixa (memantine), is only to be used in clinical studies. Nice argued that the ...

Furore over who gets Alzheimer's drug in the UK  -  Nov 20, 2006
News-Medical.net,...rivastigmine). Another drug, Ebixa (memantine), which improves severe behavioural problems is only to be used in clinical studies.

Testing Drugs to Treat Huntington’s 11/14/06  -  Nov 13, 2006
Genomics & Proteomics,...against Huntington’s disease, say scientists at University of Texas Southwestern Medical Center, Dallas, who found that two compounds—memantine and riluzole ...

Panel convened by Alzheimer's Drug Discovery Foundation makes ...  -  Nov 23, 2006
Therapeutics Daily (subscription) (press release),...options have been developed. These include memantine, a N-methyl-D-asparate (NMDA) antagonist approved for moderate to severe ...

H.Lundbeck A/SInterim report for the third quarter of 2006  -  Nov 15, 2006
PharmaLive.com (press release),Memantine, the active ingredient in Ebixa®, is currently the second-most prescribed pharmaceutical in Europe for treating Alzheimer’s disease. ...

Dutton Associates Announces Investment Opinion: Neurobiological ...  -  Nov 13, 2006
Business Wire (press release),...investment in NTI rests on the results of the Viprinex trials with some protection on the downside being afforded by the growing royalty revenue from Memantine ...

Neurobiological Technologies Receives $1.6 Million Quarterly ...  Aug 1, 2006
...(NTI(R)) (Nasdaq: NTII), today announced it has received approximately $1,569,000 from Merz Pharmaceuticals GmbH for sales of Memantine for the treatment of ... -PR Newswire

Neurobiological Technologies gets $1.6M payment  Aug 1, 2006
The payment is for sales of the drug Memantine -- a treatment for Alzheimer's disease -- during the quarter by Merz and its partner companies. ... -San Francisco Business Times

Wachovia to split operations after Golden West purchase  Aug 1, 2006
...(NTII) Tuesday announced it has received $1,569,000 from Germany's Merz Pharmaceuticals GmbH for sales of its Alzheimer drug Memantine. ... -San Jose Mercury News

Lundbeck shares slip as profits slide  Aug 16, 2006
Cipralex (escitalopram oxalate) by Lundbeck were 856 million crowns in the second quarter, up 31%, while Alzheimer's disease drug Ebixa (memantine) climbed 27 ... -Pharma Times (subscription)



Forest and Almirall Announce a Development and Marketing ...  Apr 10, 2006
...for adults for the initial and maintenance treatment of major depressive disorder and for generalized anxiety disorder; Namenda(R) (memantine HCl), an N-methyl ... - Finanzen.net

Stanford Seeks Volunteers for Two Alzheimer's Studies  Mar 27, 2006
The researchers want to determine if the drug Memantine is as effective in patients diagnosed with mild cases of Alzheimer's disease or its precursor, mild ... - Genetic Engineering News

The Seven Major Markets for Alzheimer's Disease is Expected to Be ...  Apr 5, 2006
...about a neuroprotective effect. Currently the only approved neuroprotective therapy in is memantine. Management of these patients ... - Genetic Engineering News

Treating Alzheimer's Disease  Mar 15, 2006
But Some Medications Are Slowing Down The Disease. But Now A New Study Shows Memantine May Work Better In Patients With More Severe Alzheimer's. ... - CBS 5 - Green Bay

Alzheimer's hits a century, not out  Mar 31, 2006
Another drug called memantine (Ebixa), which is used in conjunction with any one of the three, costs users an additional $170 per month and is not funded by ... - Australian

Drug 'treats severe Alzheimer's'  Mar 22, 2006
Ms Wood said only one other anti-Alzheimer's drug, memantine, had been shown to benefit patients in the later stages of the disease. ... - BBC News

Drug 'reverses' Alzheimer's  Mar 22, 2006
Results of the tests were similar to those for a more established Alzheimer's drug, memantine, whose methodology the scientists followed. ... - InTheNews.co.uk

Aricept data support use in severe Alzheimer's  Mar 23, 2006
...million last year, rise of 12% - and also allow it to also make inroads in territory current held by Forest Laboratories' Namenda (memantine), currently the ... - Pharma Times (subscription)



Drug May Help Patients With Severe Alzheimer's  07 Mar 2006
...moderate symptoms. But now a new study says another drug called Memantine may work in patients who have more severe Alzheimer's. Dr ... - CBS4Boston,

Alzheimer’s Disease Questions and Answers  Feb 28, 2006
...the other medications. Namenda (memantine) is the first drug approved for the treatment of moderate to severe AD. Namenda is an ... - KPHO Phoenix,

Neurobiological Technologies Inc. Receives $1.4 Million Quarterly ...  Feb 1, 2006
...received a royalty payment of $1,365,850 million from Merz Pharmaceuticals GmbH (Merz) for sales in the quarter ended September 30, 2005 of Memantine for the ... - Yahoo! News

Replidyne and Forest Laboratories Announce FDA Acceptance for ...  Feb 23, 2006
...indicated for the initial and maintenance treatment of major depressive disorder and for generalized anxiety disorder in adults; Namenda(R) (memantine HCl), an ... - Finanzen.net,

Immune to Fear  Feb 14, 2006
The scientists determined just how the cells died by giving the mice memantine (which blocks the NMDA receptor) prior to opening the blood-brain barrier: The ... - American Scientist

Evotec completes Phase I component for Alzheimer’s drug  Feb 8, 2006
Nevertheless, memantine, a relatively low affinity, non-selective NMDA receptor blocker has been recently approved in both the US and Europe for the treatment ... - In-PharmaTechnologist.com,

Trapeze expands in Europe  Feb 1, 2006
...(NTII) received a royalty payment of $1.37 million from Merz Pharmaceuticals GmbH for sales of Alzheimer's drug Memantine during the quarter ended Sept. 30. ... - San Jose Mercury News,

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