Recent news on Mercaptopurine

Ulcerative Colitis Study Shows Remicade Responders Maintained ...  -  May 24, 2007
eMaxHealth.com,These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE or other TNF blockers, your risk for developing

Personalized Medicine: Dream or Reality?  -  Apr 6, 2007
Drug Discovery & Development,The most developed example in oncology is the normal inactivation of 6-mercaptopurine (6-MP) by thiopurine-S-methyltransferase (TPMT), which was first

European Union CHMP Recommends Approval of First and Only Biologic ...  -  Apr 2, 2007
Drug Newswire (press release),Rarely, children and young adults who have been treated for Crohn's disease with REMICADE in combination with azathioprine or 6-mercaptopurine have

REMICADE(R) Receives Approval in European Union for Dosing ...  -  Mar 30, 2007
Drug Newswire (press release),These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE or other TNF blockers, your risk for developing

European Union CHMP Recommends Approval of First and Only Biologic ...  -  27 Mar 2007
PipelineReview.com (press release),Rarely, children and young adults who have been treated for Crohn's disease with REMICADE in combination with azathioprine or 6-mercaptopurine have

REMICADE(R) Receives Approval in European Union for Dosing ...  -  Mar 1, 2007
Earthtimes.orgThese patients also were receiving drugs known as azathioprine or6-mercaptopurine. If you take REMICADE or other TNF blockers, your risk fordeveloping

REMICADE(R) Therapy Shown to Improve Productivity in Patients ...  -  Feb 7, 2007
Drug Newswire (press release),These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE or other TNF blockers, your risk for developing

REMICADE(R) Receives Approval in European Union for Shortened ...  -  Dec 17, 2006
Drug Newswire (press release),These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE or other TNF blockers, your risk for developing

Combination Treatment Highly Effective for Long-Term Survival in ...  -  Dec 12, 2006
DG News...received 3 courses of consolidation chemotherapy followed by 5 cycles of sequential treatment of ATRA, As2O3 and 6-mercaptopurine-plus-methotrexate.

Ask A doctor: Aggressive treatment of childhood leukemia results ...  -  Dec 11, 2006
Asheville Citizen-Times,Dr. Gertrude Elion discovered one of the first effective drugs (6-mercaptopurine or 6 MP), an agent still used today. In 1988, she won the Nobel Prize in

6-mercaptopurine Remains Standard Agent for Acute Lymphoblastic ...  Oct 16, 2006
According to an article published in The Lancet, 6-mercaptopurine remains the standard thiopurine in the treatment of pediatric acute lymphoblastic leukemia. ... -Cancer Consultants (press release), Mercaptopurine Confirmed Preferable to Thioguanine for Childhood ...  Oct 17, 2006
Council’s ALL97 trial have reported that maintenance 6-thioguanine (6-TG) causes excess toxicity and no overall benefit compared to 6-mercaptopurine (6-MP ... -Cancer Consultants (press release), No Advantage Found for 6-Thioguanine in Childhood ALL  Oct 13, 2006
13 -- Children with acute lymphoblastic leukemia (ALL) had half the isolated CNS relapse rate when treated with 6-thioguanine versus 6-mercaptopurine, but the ... -MedPage Today, Remicade Receives EU Approval as Second-Line Therapy for Patients ...  Oct 15, 2006
Tract," an investigator-initiated, randomized, multicenter, placebo-controlled study evaluated the combination of Azathioprine or 6-mercaptopurine (AZA or 6-MP ... -PharmaLive.com (press release), Data Show Treatment With Remicade Reduced Hospitalizations For ...  Oct 27, 2006
...often results in death. These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE ... -Medical News Today (press release), REMICADE(R) Receives EU Approval as Second-Line Therapy for ...  Oct 8, 2006
Tract," aninvestigator-initiated, randomized, multicenter, placebo-controlled studyevaluated the combination of Azathioprine or 6-mercaptopurine (AZA or 6-MP ... -Earthtimes.org International Approvals: Lyrica and Remicade  Oct 16, 2006
The GETAID study evaluated the combination of azathioprine (AZA; 2 to 3 mg/day) or 6-mercaptopurine (6-MP; 1 to 1.5 mg/kg/day) in patients with steroid ... -Medscape (subscription) Salix Pharmaceuticals Reports American College of Gastroenterology ...  Oct 24, 2006
Washington, DC, et al., conducted a case review of three Crohn's Disease patients who had experienced flares while receiving 6-mercaptopurine and were ... -Genetic Engineering News (press release), Combination Treatment Highly Effective for Long-Term Survival in ...  -  12 Dec 2006
DG NewsCR, they received 3 courses of consolidation chemotherapy followed by 5 cycles of sequential treatment of ATRA, As2O3 and 6-mercaptopurine-plus-methotrexate. ...

Ask A doctor: Aggressive treatment of childhood leukemia results ...  -  Dec 11, 2006
Asheville Citizen-Times,1940s. Dr. Gertrude Elion discovered one of the first effective drugs (6-mercaptopurine or 6 MP), an agent still used today. In ...

Impact of Rheumatoid Arthritis Goes Beyond Signs and Symptoms ...  -  Nov 13, 2006
Earthtimes.org...have developed a rare type of lymphoma that often results in death.These patients also were receiving drugs known as azathioprine or6-mercaptopurine. ...

Impact Of Rheumatoid Arthritis Goes Beyond Signs And Symptoms ...  -  Nov 14, 2006
Medical News Today (press release),...often results in death. These patients also were receiving drugs known as azathioprine or 6- mercaptopurine. If you take REMICADE ...

Parents May Err With ALL Kids' Home Chemotherapy  Aug 14, 2006
One child was receiving a 57% overdose of Purinethol (mercaptopurine) which could have led to life-threatening infection, the investigators said. ... -MedPage Today

FDA Expands Remicade® (Infliximab) Psoriatic Arthritis Indication ...  Aug 20, 2006
...often results in death. These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE ... -Medical News Today

Health Canada Endorsed Important Safety Information on Remicade ...  Jul 27, 2006
...death. · All cases reported concomitant or past use of other immunosuppressive agents, including azathioprine or 6-mercaptopurine. ... -DG News

REMICADE(R) Receives EU Approval as Monotherapy for Treatment of ...  Jul 25, 2006
All of these hepatosplenic T-cell lymphomas with REMICADE have occurred in patients on concomitant treatment with azathioprine or 6-mercaptopurine. ... -PR Newswire UK

Advances in the Use of Nonbiologic Agents to Treat Inflammatory ...  Jun 22, 2006
6-thioguanine nucleotides (6-TGN) are known to be the active metabolites of both AZA* and 6-mercaptopurine (6-MP).* The principal metabolites of 6-TGN are 6 ... -Medscape (subscription)

FDA Accepts REMICADE(R) Supplemental Biologics License Application ...  Jun 22, 2006
...often results in death. These patients also were receiving drugs known as azathioprine or 6-mercaptopurine. If you take REMICADE ... -Medical News Today



International Approvals: Invirase and Remicade  May 15, 2006
The product is intended for use in patients who have had an inadequate response to conventional therapy (including corticosteroids and 6-mercaptopurine [6-MP ... - Medscape (subscription)

Schering-Plough Reports Financial Results for First Quarter of ...  Apr 20, 2006
...ulcerative colitis (UC) in patients who have had an inadequate response to conventional therapy, including corticosteroids and mercaptopurine or azathioprine ... - PR Newswire





Dr. Joseph H. Burchenal, Who Devised Cancer-Drug Therapy, Dies  Mar 15, 2006
...clinical trials. An early success involved the treatment of leukemia in children with the compound 6-mercaptopurine. Dr. Burchenal ... - New York Times



Some NSAIDS Safe in Ulcerative Colitis or Crohn's -- Sometimes  Feb 3, 2006
...who were in exacerbation, and patients in the study were on maintenance therapy with 5-aminosalicylate medications and/or azathioprine or 6-mercaptopurine. ... - MedPage Today

Personalised Medicine: A Revolution In Healthcare  Jan 18, 2006
In cancer chemotherapy of acute lymphocytic leukemia, administration of drugs such as 6-mercaptopurine , 6-thioguanine, and azathioprine can cause severe ... - Express Healthcare Management

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