Recent news on Metformin

EMEA Statement On Recent Publication On Cardiac Safety Of ...  -  25 May 2007
Medical News Today (press release),...maleate) Tablets, Avandamet (rosiglitazone maleate and metformin hydrochloride) Tablets, and Avaglim (rosiglitazone maleate and glimepiride) Tablets are

Avandia is safe, says drug maker  -  May 23, 2007
Malay Mail,GSK said data from ADOPT showed that the overall risk of serious cardiovascular events for patients on Avandia was comparable to metformin and sulfonylurea

More on Avandia  -  May 23, 2007
ScienceBlogsImportantly, ADOPT also demonstrated that Avandia was superior to metformin and sulfonylurea regarding longterm control of blood sugar over five years,

GSK strongly disagrees with conclusions reached in NEJM article on ...  -  May 22, 2007
News-Medical.net,Importantly, ADOPT also demonstrated that Avandia was superior to metformin and sulfonylurea regarding long-term control of blood sugar over five years,

GlaxoSmithKline responds to NEJM article on Avandia  -  May 22, 2007
WebWire (press release),Importantly, ADOPT also demonstrated that Avandia was superior to metformin and sulfonylurea regarding long-term control of blood sugar over five years,

Unanswered Questions About Avandia  -  May 22, 2007
ScienceBlogsSo if you look at the table of included studies, "placebo" is sometimes an inert pill, other times it's insulin, other times it's metformin, metformin plus

Intensive Glucose Control in Elderly Adults  -  May 22, 2007
Journal of American Medical Association (subscription),Nonetheless, when this patient taking a combination of metformin, glyburide, and rosiglitazone had a HbA 1C value of 6.9%, the rosiglitazone dose was

Combined Low-Dose Pioglitazone, Flutamide, and Metformin for Women ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,...women is combined androgen receptor blockade (with flutamide; Flu), insulin sensitization (with metformin; Met) plus an estroprogestagen contraceptive.

Aurobindo Pharma gets Metformin marketing nod from South Africa ...  -  Apr 26, 2007
ABCmoney.co.uk,Metformin was originally discovered by Bristol-Myers Squibb Co, and is mostly used in Type 2 diabetes especially in obese and insulin resistance cases.

Clinical Trials Update: May 21, 2007  -  May 21, 2007
Austin American-Statesman (subscription),To be eligible, you must be between the ages of 18 and 75, be diagnosed with type 2 diabetes, and be receiving either metformin-only based medication for at

Nutrition Wise: Broth and Sodium, Rye Bread, B12 and Medication ...  -  May 17, 2007
Kansas City infoZine,One diabetes medication, metformin, has been shown to indirectly decrease B12 absorption in 10 to 30 percent of users after three or more years' use.

Glaxo's Avandia Risks Prompt Doctors to Switch Drugs (Update7)  -  May 23, 2007
BloombergOther types of drugs offer diabetes patients possible options, such as metformin, which slows the absorption of sugar; injections of the hormone insulin;

The rebirth of a known remedy  -  May 9, 2007
Montclair Times,Others tried metformin, a drug widely used to treat diabetes that has been on the market for about 10 years. It is also considered a more modern treatment

What Diabetes Patients Need to Know  -  May 21, 2007
Wall Street Journal (subscription),For instance, metformin is associated with some weight loss, or at least is weight-neutral, Dr. Kirkman says, while the sulfonylureas and insulin can cause

New injectable treatment for type II diabetes  -  Apr 26, 2007
Healthcare RepublicLilly has launched Byetta (exenatide) for the treatment of type II diabetes mellitus, in combination with metformin and/or sulphonylureas, in patients who

Aurobindo to market diabetes drug in S Africa  -  Apr 26, 2007
Economic Times,MUMBAI: After USA, Aurobindo Pharma is all set to market its diabetes drug Metformin tablets in South Africa, as it has received marketing authorisation

Aurobindo receives Eighth approval from MCC South Africa  -  Apr 26, 2007
Equity Bulls,The Council has approved Metformin tablets in 500mg, 850mg and 1gm strengths. South African market is highly regulated and very important in its

Heart Attack Risk Seen in Drug for Diabetes  -  May 22, 2007
Times Daily (subscription),Patients who are newly discovered to have Type 2 diabetes generally receive another oral drug, metformin, as the first-line treatment, with Avandia among

Explanation of Polycystic Ovarian Syndrome PCOS  -  May 21, 2007
DentalPlans.com,...(I had been having a lot of days that I just felt like I was in a fog) To me metformin has been like a miracle drug. When I was on this I started loosing

Giving drug to prevent diabetes no DREAM solution, researchers say  -  Apr 26, 2007
Canada.com,The group reviewed evidence on it and two other drugs - metformin and acarbose - for a consensus article published this month in Diabetes Care.

Exenatide Similar to Insulin in Reducing Blood Glucose, but Also ...  -  Apr 26, 2007
DG NewsTrial A was a 26-week parallel group trial in 549 patients treated with metformin and sulfonylurea. Trial B was a two-period, 16-week crossover study in

The monster that can help to lick diabetes  -  May 21, 2007
Times Online,It is used in conjunction with metformin or one of the glitazones, other oral preparations that have been used for 20 or 30 years to treat type 2 diabetes.

Diabetes drug comes from poison lizard  -  May 10, 2007
United Press InternationalDuring a trial, 46 percent of human subjects given exenatide along with the current treatment drug metformin were able to control their blood-sugar levels

Drug may not be easy solution to diabetes  -  Apr 27, 2007
London Free Press,The group reviewed evidence on it and two other drugs -- metformin and acarbose -- and recommended lifestyle modification as the first line of approach for

No periods, small uterus and baby worries  -  May 6, 2007
Jamaica Observer,Polycystic ovarian disease can be treated by weight loss, Clomiphene citrate and Metformin. This form of treatment will induce ovulation and help you to

Diet and Exercise Can Turn Pre-Diabetes Around  -  Apr 25, 2007
About - News & Issues,The group that received metformin had a 31 percent lower occurrence of type 2 diabetes. Of the over 21 million people in the US who have diabetes,

Diabetes pill raises risk of heart attacks, study suggests  -  May 22, 2007
HULIQ,It also is combined with metformin and sold as Avandamet. Only one other drug like it - pioglitazone, sold as Actos and Actoplus Met by Takeda

Diabetes drug called potential death risk  -  May 22, 2007
9NEWS.com,Another drug, metformin, reduces the amount of sugar produced in the liver. Unlike older drugs, insulin sensitizers such as Avandia and Actos can be taken

Should Diabetes Patients Stop Taking Avandia?  -  May 22, 2007
News Locale,...myocardial infarction, and stroke, or MACE endpoint] for patients on Avandia was comparable to metformin and sulfonylurea (glyburide) -- two of the most

Diabetes Pill Tied to Heart Risks  -  May 22, 2007
Newsday,It also is combined with metformin and sold as Avandamet. Only one other drug like it -- pioglitazone, sold as Actos and Actoplus Met by Takeda

Depomed to Present at the Bank of America 2007 Healthcare Conference  -  May 22, 2007
PharmaLive.com (press release),Glumetza(TM) (metformin hydrochloride extended release tablets) is approved for use in adults with type 2 diabetes and is being marketed in the United

New safety issue spurs calls for FDA overhaul  -  May 22, 2007
Fort Worth Star Telegram,It is also combined with metformin and sold as Avandamet. Only one other drug like it -- pioglitazone, sold as Actos and Actoplus Met by Takeda

Study: Diabetes Pill Raises Risk Of Heart Attacks  -  May 22, 2007
TheDay,It also is combined with metformin and sold as Avandamet. Only one other drug like it — pioglitazone, sold as Actos and Actoplus Met by Takeda

FDA in trouble over widely used diabetic drug Avandia  -  May 22, 2007
News-Medical.net,It is also combined with metformin and sold as Avandamet. GlaxoSmithKline also has been testing Avandia to try to prevent diabetes in those at high risk of

Diabetes warning feeds debate over drug safety  -  May 22, 2007
Seattle Times,Treatments include insulin, the sulfonylurea drugs and the meglitinide drugs, which stimulate the release of insulin; biguanides such as metformin,

Aurobindo Pharma gets Metformin marketing nod from South Africa ...  -  26 Apr 2007
ABCmoney.co.uk,Metformin was originally discovered by Bristol-Myers Squibb Co, and is mostly used in Type 2 diabetes especially in obese and insulin resistance cases.

New injectable treatment for type II diabetes  -  26 Apr 2007
Healthcare RepublicLilly has launched Byetta (exenatide) for the treatment of type II diabetes mellitus, in combination with metformin and/or sulphonylureas, in patients who

Aurobindo to market diabetes drug in S Africa  -  26 Apr 2007
Economic Times,MUMBAI: After USA, Aurobindo Pharma is all set to market its diabetes drug Metformin tablets in South Africa, as it has received marketing authorisation

Aurobindo receives Eighth approval from MCC South Africa  -  26 Apr 2007
Equity Bulls,The Council has approved Metformin tablets in 500mg, 850mg and 1gm strengths. South African market is highly regulated and very important in its

Exenatide Similar to Insulin in Reducing Blood Glucose, but Also ...  -  26 Apr 2007
DG NewsTrial A was a 26-week parallel group trial in 549 patients treated with metformin and sulfonylurea. Trial B was a two-period, 16-week crossover study in

Diet and Exercise Can Turn Pre-Diabetes Around  -  26 Apr 2007
About - News & Issues,The group that received metformin had a 31 percent lower occurrence of type 2 diabetes. Of the over 21 million people in the US who have diabetes,

Governments Must Act on Biggest Epidemic in Human History  -  26 Apr 2007
Canada NewsWire (press release),Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346: 393-403 (6) Kosaka K, Noda M, Kuzuya T. Diab

Nip diabetes in the bud  -  Apr 23, 2007
New Straits Times,The study, called A Diabetes Outcome Progression Trial (adopt), was the first to directly compare a TZD to metformin (a biguanide) and glyburide (a

Cholesterol-Lowering Drug Combined With Metformin Improves Glucose ...  -  Apr 16, 2007
DG NewsSubjects had type 2 diabetes not adequately controlled on metformin alone or metformin in combination with additional oral antidiabetic agents.

Mylan Announces Final FDA Approval for Glipizide and Metformin ...  -  Apr 16, 2007
Drug Newswire (press release),Glipizide and Metformin Hydrochloride Tablets are the generic version of Bristol Myers Squibb's Metaglip(TM) Tablets. Glipizide and Metformin Hydrochloride

Mylan Unveils FDA Approval For Glipizide And Metformin ...  -  Apr 13, 2007
Trading Markets,The Canonsburg, Pennsylvania-based company noted that the Glipizide and Metformin Hydrochloride Tablets are the generic version of Bristol Myers Squibb's

Mylan Laboratories (MYL) Receives Final FDA Approval for Glipizide ...  -  Apr 13, 2007
StreetInsider.com (subscription),Glipizide and Metformin Hydrochloride Tablets are the generic version of Bristol Myers Squibb's (NYSE: BMY) Metaglip Tablets.

Mylan Pharma. Gets Final FDA Approval For Glipizide And Metformin ...  -  Apr 13, 2007
Trading Markets,The company noted that the products that are planning to be shipped immediately, Glipizide and Metformin Hydrochloride Tablets are the generic version of

Synovics Pharmaceuticals Appoints David Coffin-Beach President and ...  -  Apr 25, 2007
PharmaLive.com (press release),In July 2006 Synovics announced the approval of its first Abbreviated Drug Application (ANDA) by the FDA, 500 mg metformin XR. Synovics is in the process of

FDA Okays Sitagliptin (Januvia)-Metformin Combo Tablet  -  Apr 3, 2007
MedPage Today,Called Janumet, the new product combines sitagliptin (Januvia) and metformin, and was indicated by the FDA for type 2 patients who have not achieved

Anti-diabetes drug slows progressive loss of sugar control in ...  -  Apr 20, 2007
exduco.net,In this double-blind, randomized, controlled clinical trial, researchers compared rosiglitazone with metformin andglyburide over an average of four years of

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,The combination pills that are currently marketed incorporate the older drugs such as sulfonylureas and metformin either together or with glitazones,

FDA Approvals: Janumet  -  Apr 12, 2007
Medscape (subscription)April 12, 2007 — The US Food and Drug Administration (FDA) has approved sitagliptin plus metformin HCl tablets for use as an adjunct to diet and exercise to

JANUVIA™ Approved in the European Union for the Treatment of Type ...  -  Apr 18, 2007
Diabetes Health (press release),JANUVIA is indicated in patients with type 2 diabetes to improve glycemic control in combination with metformin when diet and exercise plus metformin do not

FDA Approves JANUMET for Type 2 Diabetes  -  Apr 2, 2007
Playfuls.com,The FDA approved JANUMET based upon clinical data including sitagliptin plus metformin as separate tablets. A clinical bioequivalence study has demonstrated

Two, Two, Two Pills in One: Meet Janumet  -  Apr 20, 2007
Diabetes Health (press release),The FDA has approved Janumet, Merck’s merge of metformin and Januvia into one pill, for use with type 2 diabetes in the United States.

Oral medications to treat Type 2 diabetes  -  Apr 19, 2007
Chennai Online,The generic drug (Metformin) is now made by a variety of companies after the expiration of the patent in the US. Metformin is, by far, the most prescribed

Fast-track approval for diabetes drug  -  Apr 20, 2007
Gulf News,...combination pill for diabetes-related illnesses available here was not diabetes-specific as it combines a morphine-based painkiller with metformin.

FDA Approves JANUMET(TM) for Type 2 Diabetes, Offering Powerful ...  -  Apr 2, 2007
PipelineReview.com (press release),JANUMET (sitagliptin/metformin HCl) provides significantly greater A1C1 reduction than metformin alone and helped more than twice as many patients get to

Two drugs comparable for diabetes in children  -  Apr 16, 2007
Scientific AmericanTo investigate further, the researchers randomly assigned 285 subjects who were an average of 14 years old to receive glimepiride once daily or metformin

FDA Approves New Drug for Type 2 Diabetes  -  Apr 3, 2007
FOX NewsIt's the first and only tablet that combines Januvia and metformin, notes Merck, the drug company that makes Janumet and Januvia.

UAE to clear diabetes drug  -  Apr 20, 2007
Business Portal 24 (press release),Health authorities in the UAE have said approval for a pill combining two medications, Januvia and metformin, for the treatment of diabetes, which is rife

Exenatide in Combination Therapy: Small Study, Big Market, and ...  -  Apr 2, 2007
Annals of Internal MedicineThe FDA had previously approved exenatide in combination with metformin or sulfonylureas. The regulatory barriers for approving a new indication for a drug

Research Roundup  -  Apr 3, 2007
UPENN Almanac,Researchers from Penn’s School of Medicine and the National Institutes of Health Reproductive Medicine research network have found that metformin,

New Genetic Test for Diabetes Launched  -  Apr 19, 2007
Associated Content,...persons identified to be at-risk will modify their lifestyles to include weight loss, appropriate diet, and medications such as Metformin, which help

FDA Approves Janumet for Type 2 Diabetes  -  Apr 2, 2007
SpiritIndia,Janumet (sitagliptin/metformin HCl) provides significantly greater A1C1 reduction than metformin alone and helped more than twice as many patients get to

FDA Approves Combination Drug Janumet For Type 2 Diabetes  -  Apr 3, 2007
Medical News Today,Metformin is an oral drug in the biguanide class. It is the most widely used drug in the treatment of diabetes in the US and was first made by Bristol-Myers

Depomed Files Prior Approval Supplement for 1000 mg Strength ...  -  Apr 2, 2007
PharmaLive.com (press release),Glumetza(TM) (metformin hydrochloride extended release tablets) is indicated alone or in combination with sulfonylurea or insulin as an adjunct to diet and

Depomed Files Prior Approval Supplement for 1000 mg Strength ...  -  Apr 2, 2007
Business Wire (press release),Glumetza™ (metformin hydrochloride extended release tablets) is indicated alone or in combination with sulfonylurea or insulin as an adjunct to diet and

Combo drug for Type 2 diabetes gets FDA blessing  -  Apr 2, 2007
Arizona Daily Star,Janumet combines Merck's Januvia, approved in the US last year, with the older drug metformin for treating Type 2 diabetes.

GCI to assist Merck rollout of Janumet  -  Apr 4, 2007
PRWeek (subscription),Janumet is a two-in-one tablet containing a Merck drug called Januvia and an older drug metformin. Januvia was approved last October by the FDA,

Merck gains on US approval for combo diabetes pill  -  Apr 2, 2007
Reuters.uk,Janumet, by combining Januvia and metformin into a single product, is meant to help patients with Type 2 diabetes better control their blood sugar.

Insulin Analogs or Premixed Insulin Analogs in Combination With ...  -  Apr 17, 2007
Medscape (subscription)United Kingdom prospective diabetes study (UKPDS) 13: relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with

Market Report -- In Play (MYL)  -  Apr 13, 2007
MSN MoneyMylan Labs announces final FDA approval for glipizide and metformin hydrochloride tablets Co announces that Mylan Pharmaceuticals has received final

Merck's Janumet, Pill for Diabetes, Approved by US (Update2)  -  Apr 1, 2007
BloombergJanumet combines Merck's Januvia, approved in the US last year, with the older drug metformin for treating type-2 diabetes. The new pill was cleared for

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