Recent news on Metyrapone

Effects of Peroxisome Proliferator-Activated Receptor- and ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,...mRNA or activity in sc adipose tissue, and insulin sensitization was unaffected by glucocorticoid blockade with a combination of metyrapone and RU38486.

Astex Grants Cytochrome P450 License to GlaxoSmithKline  -  Apr 24, 2007
CNW Telbec (Communiqués de presse),...(1) Williams et al (2004) 'Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone', Science Magazine, 2004 Jul 30:305 (5684):

UCSF Researchers Seek Volunteers for Study on Connections Between ...  -  Feb 26, 2007
UCSF Today,On the final night, the volunteers are given metyrapone, a medication that stimulates production of CRF in the brain.

Diminished Glucocorticoid Negative Feedback in Polydipsic ...  -  Feb 6, 2007
Journal of Clinical Endocrinology and Metabolism,Intervention: Metyrapone (750 mg) was administered orally at 1430 and 1900 h. Beginning at 1930 h, hydrocortisone was infused over 150 min at 0.03 mg/kg·h.

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