Recent news on Mitomycin

AUA 2007 - Plenary Session - 2007 AUA Guidelines on Bladder Cancer ...  -  May 22, 2007
UroToday,Specifically, the panel recommends that patients who present with a lesion have it resected, and consideration be given to peri-operative mitomycin with

Glaucoma surgery: When should we expect something better?  -  May 11, 2007
OSN SuperSite (subscription),Instead, efforts have been directed toward modulation of the eye’s wound-healing response with agents including corticosteroids, 5-fluorouracil, mitomycin-C

AUA 2007 - SUO Session: Transitional Cell Carcinoma – Optimizing ...  -  May 20, 2007
UroToday,The first question posed was whether patients who present with a new diagnosis of bladder tumor should receive intravesical mitomycin as is recommended by

SuperGen Reports 2007 First Quarter Financial Results  -  May 2, 2007
PR Newswire (press release),April 2007: The Company announced that it sold the rights to the generic anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2

Thallion Pharmaceuticals Inc. Hires Executive Vice-President ...  -  Apr 25, 2007
Web Services Journal,Like well known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a nonpathogenic microorganism. However, unlike these drugs that were

Supergen Sells Select Non-Core Assets to Intas  -  Apr 20, 2007
PR Newswire (press release),Mitomycin and Paclitaxel rights sold for $1.2 million DUBLIN, Calif., April 20 /PRNewswire-FirstCall/ -- SuperGen Inc. (Nasdaq: SUPG) today announced that

Supergen Sells Select Non-Core Assets to Intas  -  Apr 20, 2007
PharmaLive.com (press release),...that it signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2 million.

Supergen Sells Select Non-Core Assets to Intas  -  Apr 20, 2007
Earthtimes.orgDUBLIN, Calif., April 20 -- SuperGen Inc. today announced that it signed a definitive agreement to sell the rights to anticancer agents mitomycin and

Study finds limited benefit from needling revision with MMC of ...  -  Apr 19, 2007
OSN SuperSite (subscription),Needling bleb revision with mitomycin-C can be used to manage failed encapsulated Molteno tube implants, according to a study by researchers in Iran.

SuperGen to sell anti-cancer agents rights for $1.2 million  -  Apr 20, 2007
Reuters India,Reuters - SuperGen Inc. said it agreed to sell the rights of its anti-cancer agents, mitomycin and paclitaxel, to Intas Pharmaceuticals Ltd. for $1.2

SuperGen Sells Drugs for $1.2 Million  -  Apr 20, 2007
Forbes,Pharmaceutical company SuperGen Inc. said Friday it will the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2

SuperGen sells anti-cancer agents to Intas  -  Apr 20, 2007
United Press InternationalThe two agents, mitomycin and paclitaxel, were part of SuperGen's initial strategy to gain entrance into the oncology market through generic products before

Supergen (SUPG) Announces Sale of Select Non-Core Assets to Intas  -  Apr 20, 2007
StreetInsider.com (subscription),SuperGen Inc. (Nasdaq: SUPG) has signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals

Market Report -- In Play (SUPG)  -  Apr 20, 2007
MSN MoneySuperGen sells select non-core assets to Intas Co announces it signed a definitive agreement to sell the rights to anticancer agents mitomycin and

Thallion Pharmaceuticals Inc. Hires Executive Vice-President ...  -  Apr 25, 2007
Web Services Journal,Like well known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a nonpathogenic microorganism. However, unlike these drugs that were

Thallion Pharmaceuticals Inc. Announces Update of Recent FDA ...  -  Apr 13, 2007
Web Services Journal,Like well known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a nonpathogenic microorganism. However, unlike these drugs that were

Keys to success with surface ablation  -  Apr 10, 2007
OSN SuperSite (subscription),Mitomycin can be administered with ablations to treat patients who have myopia greater than 6 D or who are younger than 30 years old, but it should not be

Gran denied NHS treatment dies of cancer  -  Apr 4, 2007
ic SurreyOnline.co.uk,Cold-hearted health chiefs refused to pay for a drug called Mitomycin C, leaving Mrs Davies to find £15000 to fund her treatment.

Appendix Tumor Patient Perseveres  -  Apr 2, 2007
CancerWiseThe abdominal cavity is filled with mitomycin C, a chemotherapy drug heated to 41 degrees Celsius (106º F). For 90 minutes, surgeons rock the patient back

Management Of Superficial Urothelial Tumors  -  Apr 2, 2007
Medical News Today (press release),Dr. Witjes, Nijmegen, The Netherlands presented "Intravesical Hyperthermia and Mitomycin-C for BCG Refractory CIS of the Urinary Bladder".

Trabeculectomy with MMC lowered IOP in patients with secondary ...  -  Feb 16, 2007
OSN SuperSite (subscription),Most eyes treated with trabeculectomy with mitomycin-C for secondary glaucoma from Behçet's disease achieved an IOP of 20 mm Hg or below at 1 year postop,

Data acquisition for the histoculture drug response assay in lung ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryConcentrations of drugs were 20 µg/mL for cisplatin (CDDP), 300 µg/mL for 5-fluorouracil (FU), 15 µg/mL for adriamycin (ADM), 2 µg/mL for mitomycin C (MMC),

Ecopia and Caprion Announce Commitments of $45 Million in ...  -  Feb 19, 2007
CCNMatthews (press release),Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil.

Glaucoma drainage device more reliable than trabeculectomy for IOP ...  -  Feb 9, 2007
OSN SuperSite (subscription),Aqueous tube shunts are significantly more likely to maintain IOP control without persistent hypotony than trabeculectomy with mitomycin-C at 1 year postop,

Battling cancer like slowly paddling upstream against currents  -  Feb 8, 2007
TopCancerNews.com,First came a mitomycin push followed by four to five days of 5-Fluorouracil. Radiation came next -- for six weeks -- and then Tanya endured another round of

Data acquisition for the histoculture drug response assay in lung ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryWe examined chemosensitivities of the tissues to cisplatin, doxorubicin, mitomycin C, 5-fluorouracil, docetaxel, paclitaxel, etoposide, irinotecan,

Ecopia’s Phase I Dose-Escalation Portion Successfully Completed  -  18 Jan 2007
PipelineReview.com (press release),Like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a non-pathogenic microorganism. However, unlike these drugs that

Fears nurses exposed to cancer risk  -  Dec 30, 2006
NEWS.com.au,World safety guidelines require staff to handle the drug, Mitomycin C, in well-ventilated areas and to wear protective clothing.

Ecopia Announces Agreement with Caprion to Combine Their ...  -  Jan 5, 2007
PipelineReview.com (press release),Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil.

Boss says staff at risk  -  Dec 30, 2006
Courier Mail,The drug, Mitomycin C, which is used to treat the hospital's bladder cancer patients, is carcinogenic to rats and potentially carcinogenic to humans.

Cancer patient awaits vital news  -  Dec 6, 2006
ic SurreyOnline.co.uk,And in May, health bosses refused to pay for a potentially life-saving drug, Mitomycin C, which Jacky's specialist said would be the best treatment for a

Ecopia Comments on Recent Market Activity  -  Dec 21, 2006
Genetic Engineering News (press release),Like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a non-pathogenic microorganism. However, unlike these drugs that

Ecopia Reaches Three Important Patent Milestones  -  Dec 12, 2006
Genetic Engineering News (press release),Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a microorganism that lives in common soil.

Oncolytics Biotech Inc. Reports REOLYSIN(R) and Chemotherapeutic ...  09 Nov 2006
In general, the combination of reovirus with cisplatin, gemcitabine, mitomycin or vinblastine was synergistic against NSCLC cell lines sensitive to anti-cancer ... -Yahoo! News (press release) Myriad Genetics Sponsors Clinical Trial in Pancreatic Cancer  Oct 24, 2006
Previous studies showed that pancreatic tumors from patients with a BRCA2 gene mutation were approximately 1,000 times more sensitive to mitomycin-C than were ... -Yahoo! News (press release) Myriad Genetics sponsors pancreatic cancer trial  Oct 25, 2006
Myriad Genetics is providing the genetic testing component of a new clinical trial to evaluate the effect of mitomycin-C in patients with pancreatic cancer. ... -Pharmaceutical Business Review Myriad Genetics Sponsors Clinical Trial in Pancreatic Cancer  Oct 24, 2006
Mitomycin-C is one member of an important class of DNA damaging agents used to treat cancer. BRCA2 is part of the DNA repair process. ... -Earthtimes.org Defective mitochondrial peroxiredoxin-3 results in sensitivity to ...  Oct 23, 2006
...overexpression of PRDX3 suppresses the sensitivity of FA-G cells to H 2 O 2 , and decreased PRDX3 expression increases sensitivity to mitomycin C. Cells from ... -Journal of Cell Biology (subscription) Myriad Sponsors Clinical Trial  Oct 24, 2006
Myriad said that the trial will determine whether the sensitivity of the pancreatic cancer to its agent mitomycin-C holds true in humans as it did in earlier ... -techrockies.com, Lung cancer response rate not improved after adding mitomycin C to ...  Aug 31, 2006
The response rate of advanced non-small cell lung cancer (NSCLC) was not improved with the addition of mitomycin C to docetaxel as second-line chemotherapy. ... -Therapeutics Daily (subscription)

Cancer sufferer 'abandoned by NHS'  Sep 13, 2006
After health bosses refused to pay for the most recent drug that she needs,Mitomycin C, she developed another tumour at the base of her brain and now has to ... -ic SurreyOnline.co.uk

Researchers from the United States and Singapore report details of ...  Sep 13, 2006
...and Pharmacology, "FR targeted drug conjugates were prepared by covalently attaching the vitamin folate, to the potent anticancer drug, mitomycin C (MMC). ... -Therapeutics Daily (subscription)

Pro Top & Mediking Receives CE Mark Approval for OculusGen(TM) ...  Sep 6, 2006
The super matrix may significantly increase the success rate by reducing intraocular fibrosis and avoiding mitomycin-C (MMC) induced complications. ... -PR Newswire UK

Mesothelioma Reseaerch Shows Promise  Aug 26, 2006
...with Platinol® (cisplatin) and Gemzar (gemcitabine) followed by Novantrone® (mitoxantrone), methotrexate and Mutamycin® (mitomycin) shows potential as an ... -World Fitness

In-vitro Study Shows ReGen's Colostrinin to Have Anti-Ageing and ...  Aug 25, 2006
...at the dose level indicated in the report, reduced the frequency of mutation caused by two mutagenic agents, methyl methan esulphonate and mitomycin-C, the ... -PharmaLive.com

Ecopia Granted US Patent on ECO-4601 Composition of Matter  Sep 7, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a microorganism that lives in common soil. ... -CCNMatthews

Ecopia Reaches Three Important Patent Milestones  -  12 Dec 2006
Market Wire (press release)Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a microorganism that lives in common soil.

Cancer patient awaits vital news  -  Dec 6, 2006
ic SurreyOnline.co.uk,And in May, health bosses refused to pay for a potentially life-saving drug, Mitomycin C, which Jacky's specialist said would be the best treatment for a

Common Virus Significantly Enhances Cancer-Fighting Ability Of ...  -  Nov 24, 2006
Medical News Today (press release),In general, the combination of reovirus with cisplatin, gemcitabine, mitomycin or vinblastine was found to be more effective against NSCLC cell lines

Virus/chemo drugs are good duo  -  Nov 20, 2006
United Press International...mitomycin, vinblastine, and paclitaxel and tested the combinations against six different chemotherapy-sensitive, non-small cell lung cancer cell lines.

5-FU/Mitomycin Remains Standard of Care for Anal Cancer  Jul 26, 2006
2006 semi-annual meeting of the Radiation Therapy Oncology Group (RTOG), treatment including the chemotherapy agents 5-fluorouracil and mitomycin-C (Mutomycin ... -Cancer Consultants

In-vitro Study Shows ReGen's Colostrinin to Have Anti-Ageing and ...  Aug 25, 2006
...at the dose level indicated in the report, reduced the frequency of mutation caused by two mutagenic agents, methyl methan esulphonate and mitomycin-C, the ... -PharmaLive.com

Mayne Pharma's Purchase of SuperGen's North American Oncology ...  Aug 23, 2006
...rubitecan) capsules, an investigational drug intended for the treatment of pancreatic cancer, Nipent(R) (pentostatin for injection), Mitomycin, SurfaceSafe(R ... -PharmaLive.com

Halozyme Therapeutics Reports Second Quarter 2006 Financial ...  Aug 10, 2006
...is designed to evaluate multiple intravesical (in the bladder) administrations of Chemophase along with the widely-used anticancer drug mitomycin, or MMC, in ... -MSN Money

5-FU/Mutomycin® Remains Standard of Care for Anal Cancer  Jul 31, 2006
Researchers affiliated with the Radiation Therapy Oncology Group (RTOG) have reported that 5-fluorouracil (5-FU) and Mutomycin (mitomycin-C) plus radiation ... -Cancer Consultants

Ecopia to Unveil New Data on ECO-4601's Mechanism of Action at the ...  Aug 17, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from a microorganism that lives in common soil. ... -Market Wire

Article by HairlossTalk.com  Aug 7, 2006
Common drugs that cause alopecia include methotrexate, cyclophosphamide, bleomycin, doxorubicin, mitomycin, cytarabine, vinblastine, and vincristine. ... -Hairloss Talk Newsletter

SuperGen Reports 2006 Second Quarter Financial Results  Jul 27, 2006
...rubitecan) capsules, an investigational drug intended for the treatment of pancreatic cancer, Nipent(R) (pentostatin for injection), Mitomycin, and Surface Safe ... -PR Newswire

RTOG: Mitomycin-5-FU-Radiotherapy Confirmed as Anal Cancer Choice  Jul 7, 2006
...rates in the Radiation Therapy Oncology Group RTOG 98-11 study were similar for both the Platinol-based regimen and a chemoradiation regimen of mitomycin-C and ... -MedPage Today

Adjuvant Mitomycin C Does Not Compensate For An Inadequate ...  Jun 25, 2006
...with clinical stage T1 disease. Does using adjuvant intravesical mitomycin C obviate the need for a repeat TUR? In the May issue ... -Medical News Today

Intravesical Taxotere® Effective in Recurrent Superficial Bladder ...  Jul 21, 2006
...drug directly into the bladder). This often consists of mitomycin C or Bacille Calmette-Guérin (BCG). BCG, an immunotherapy agent ... -Cancer Consultants

Antibiotic Stress Induces Genetic Transformability in the Human ...  Jul 6, 2006
Aminoglycoside and fluoroquinolone antibiotics, as well as mitomycin C, a DNA-damaging agent, induced transformation in Streptococcus pneumoniae. ... -Science Magazine (subscription)

Mayne Acquires SuperGen's North American Oncology Products  Jun 21, 2006
The parties are working towards executing additional agreements for the acquisition of mitomycin, a cytotoxic cancer therapeutic, for the US market as well as ... -International News Service

SuperGen's $34M Sell-Off To Mayne Includes Nipent  Jun 22, 2006
The company is negotiating further with Mayne Pharma to divest US rights to mitomycin, an approved cytotoxic cancer therapeutic, and to sell the ex-US rights ... -BioWorld Online

Ecopia Announces that the USPTO Confirms Patent Protection on ECO ...  Jul 13, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ... -Market Wire

SuperGen Announces Conference Call and Webcast  Jun 21, 2006
TM) (rubitecan) capsules, an investigational drug intended for the treatment of pancreatic cancer, Nipent® (pentostatin for injection), Mitomycin, and Surface ... -Yahoo! News



Ecopia's Annual General Meeting of Shareholders to Take Place on ...  11 Apr 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ... - Market Wire

Immediate Intravesical Mitomycin C After Bladder Tumor Resection ...  Apr 4, 2006
NEW YORK (Reuters Health) - Intravesical instillation of mitomycin C is feasible and safe to perform in the operating room immediately after transurethral ... - UroToday

Post-Operative Instillation Of Intravesical Mitomycin C Is Safe  Mar 9, 2006
...bladder. Mitomycin C (MMC) intravesical chemotherapy can be placed via a Foley catheter at the conclusion of the procedure. Following ... - UroToday

Halozyme Therapeutics Presents Preclinical and Phase I ...  Apr 4, 2006
...plasma of five bladder cancer patients dosed intravesically with 20,000 Units of rHuPH20 along with 40 mg of the commonly used chemotherapy agent mitomycin (MMC ... - PR Newswire

Halozyme Therapeutics to Present Preclinical, Toxicology and Phase ...  Mar 28, 2006
Pre-clinical data on the pharmacology and toxicology of rHuPH20, a recombinant human hyaluronidase, with mitomycin will be presented along with clinical data ... - PharmaLive.com

Halozyme Therapeutics to Present Preclinical, Toxicology and Phase ...  Mar 28, 2006
Annual Meeting in Washington, DC Pre-clinical data on the pharmacology and toxicology of rHuPH20, a recombinant human hyaluronidase, with mitomycin will be ... - PR Newswire

Halozyme Therapeutics Says Pre-clinical, Pharmacokinetic Data ...  Apr 4, 2006
...of five-bladder cancer patients dosed intravesically with 20,000 units of rHuPH20 along with 40 mg of the commonly used chemotherapy agent mitomycin, or MMC. ... - Trading Markets

Ecopia Presents Data Highlighting the Potential of Decipher'R' ...  Mar 29, 2006
The source is soil-dwelling microorganisms that have produced several potent anticancer agents such as doxorubicin, bleomycin and mitomycin. ... - CCNMatthews

SuperGen Completes Acquisition of Montigen Pharmaceuticals  Apr 5, 2006
SuperGen's product portfolio includes: Nipent(R) (pentostatin for injection); Mitomycin (generic brand of Mutamycin(R)); and SurfaceSafe(R) cleaner. - PharmaLive.com

Halozyme Therapeutics Reports Fourth Quarter and Year End 2005 ...  Mar 23, 2006
...was designed to evaluate a single intravesical (into the bladder) administration of Chemophase along with the widely used anticancer drug mitomycin in patients ... - PR Newswire

Studies: Embryonic Stem Cells As a Cure for Alzheimer's Disease  Mar 13, 2006
...like" cells, Chiba used two Embryonic Stem (ES) lines, E14.1 and R-CMTI-1. Embryonic stem cells were maintained on gelatin-coated dishes with mitomycin C (a ... - GNIF Brain Blogger

Supergen Announces Results from Combination Study in Cll Published ...  Mar 14, 2006
SuperGen's product portfolio includes: Nipent(R) (pentostatin for injection); Mitomycin (generic brand of Mutamycin(R)); and SurfaceSafe(R) cleaner. ... - PharmaLive.com



Early Chemotherapy Improves Outcomes for Mesothelioma  Feb 24, 2006
Approximately half of the patients then received immediate MVP (mitomycin, vinblastine, cisplatin, or carboplatin), while the other half did not receive MVP ... - Cancer Consultants,

SuperGen Announces 2005 Fourth Quarter and Year End Financial ...  Feb 21, 2006
SuperGen's product portfolio includes: Nipent(R) (pentostatin for injection); Mitomycin (generic brand of Mutamycin(R)); and SurfaceSafe(R) cleaner. ... - PR Newswire,

Management Changes at Ecopia  Feb 17, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ... - CCNMatthews,

SuperGen to Present at BIO CEO & Investor Conference  Feb 7, 2006
SuperGen's product portfolio includes: Nipent(R) (pentostatin for injection); Mitomycin (generic brand of Mutamycin(R)); and SurfaceSafe(R) cleaner. ... - PR Newswire

Ecopia Receives No Objection Letter from Health Canada for Cancer ...  Feb 2, 2006
Just like well-known chemotherapies such as doxorubicin and mitomycin C, ECO-4601 comes from microorganisms that live in common soil. ... - Genetic Engineering News

Novel Strategies for Treating Lung Cancer: Chemotherapy  Jan 24, 2006
Two of these trials -- ALPI (Adjuvant Lung Project Italy) [8] using MVP (mitomycin, vindesine, cisplatin) and BLT (Big Lung Trial from Great Britain) [9] using ... - Medscape (subscription)

Electromotive Mutamycin® Improves Results of BCG Therapy for ...  Jan 17, 2006
Italian researchers have reported that electromotive (intravesical electric current) Mutamycin (mitomycin) and BCG improves the outcomes of patients with ... - Cancer Consultants

SuperGen Announces Withdrawal of Orathecin Marketing Authorization ...  Jan 20, 2006
SuperGen's product portfolio includes Nipent(R) (pentostatin for injection); Mitomycin (generic brand of Mutamycin(R)); and SurfaceSafe(R) cleaner. ... - PharmaLive.com

SuperGen Announces Withdrawal of Orathecin(TM) Marketing ...  Jan 20, 2006
SuperGen's product portfolio includes Nipent® (pentostatin for injection); Mitomycin (generic brand of Mutamycin®); and SurfaceSafe® cleaner. ... - Yahoo! News

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