Recent news on N-Methyl

Forest Laboratories, Inc. and Cypress Bioscience, Inc. Announce ...  -  May 23, 2007
PharmaLive.com (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Inion obtains US patent for bone-graft technology  -  May 15, 2007
Forbes,The bone-grafting materials covered by the patent comprise porous ceramic or composite bone graft containing N-methyl-pyrrolidone (NMP).

Neurodevelopment & the Environment: Are Vaccines to Blame for ...  -  Apr 28, 2007
American Chronicle,Elevated nitric oxide/peroxynitrite theory of multiple chemical sensitivity: central role of N-methyl-D-aspartate receptors in the sensitivity mechanism.

Multiple Chemical Sensitivity (MCS) and Genetics  -  May 15, 2007
American Chronicle,Pall, M. (2003), Elevated nitric oxide/peroxynitrite theory of Multiple Chemical Sensitivity: central role of N-Methyl-D-aspartate receptors in the

Clinical Advances in Pharmacological and Integrated Treatment ...  -  May 18, 2007
Focus (subscription)...inhibition of glutamatergic transmission and subsequent reduction in withdrawal excitability, particularly via N-methyl-D-aspartate receptor sites (11).

BASF raises production capacity for THF intermediate  -  May 10, 2007
In-PharmaTechnologist.com,PolyTHF and two other products (gamma butyrolactone and n-methyl-2-pyrrolidone) would rise by €0.15/kg with effect from 1 April 2007, while the prices

Preclinical Development and Clinical Implementation of Treatments ...  -  May 18, 2007
Focus (subscription)Acamprosate is thought to have its anticraving efficacy as a partial agonist at the N-methyl-D-aspartate receptor (53), a key receptor system that is

From the analyst's couch: Therapies for Alzheimer's disease  -  May 4, 2007
Nature.com (subscription),...and the N-methyl-D-aspartate (NMDA)-receptor modulator memantine (Namenda; Forest/Lundbeck) — are approved for the treatment of symptoms of AD.

Independent publication supports the profile of CeNeS phase II ...  -  May 4, 2007
PharmaLive.com (press release),A use-dependent ligand for the N-methyl-d-aspartate receptor in rat brain. Biegon et al., Synapse, volume 61, pages 577-586, 2007.

Celecoxib Prevents Gastric Cancer In Mongolian Gerbils  -  Apr 23, 2007
Medical News Today (press release),Fifty-two Mongolian gerbils were divided into 3 groups and given 5 biweekly doses of N-methyl-N-nitrosourea (30 ppm). At week 12, group 2 (n = 20) and group

Pollutants' hazards  -  Apr 8, 2007
Flint Journal,N-Methyl-2-Pryyolidone (16028 lbs.): Developmental, cardiovascular, kidney, neurological, reproductive effects. Toluene (13900 lbs.

Forest Laboratories, Inc. Reports Fiscal Year 2007 Fourth Quarter ...  -  Apr 24, 2007
PR-Inside.com (Pressemitteilung),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Governors and Mayor Proclaim May as Multiple Chemical Sensitivity ...  -  Apr 16, 2007
American Chronicle,Elevated nitric oxide/peroxynitrite theory of multiple chemical sensitivity: central role of N-methyl-D-aspartate receptors in the sensitivity mechanism.

Neuropsychiatric Abnormalities: A New Vista From Studies on ...  -  Mar 28, 2007
Psychiatric Times,There is considerable evidence that excitatory neurotransmission via N-methyl-D-aspartate (NMDA) receptors is abnormal in schizophrenia (Tsai and Coyle,

Forest Laboratories, Inc. Sets Date and Conference Call for Fiscal ...  -  Apr 12, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Visual Assessment Versus Quantitative Assessment of 11 C-PIB PET ...  -  Mar 30, 2007
Journal of Nuclear Medicine (subscription)Amyloid-ß (Aß) imaging with N-methyl- 11 C-2-(4'-methylamino-phenyl)-6-hydroxy-benzothiazole ( 11 C-6-OH-BTA-1; also known as 11 C-PIB) shows a robust

Full Text  -  Mar 1, 2007
Science Magazine (subscription)Associative N-methyl-D-aspartate receptor (NMDAR)–dependent LTP is induced by coincident activity in afferent pathways sufficient to depolarize postsynaptic

Effect of Memantine on Cue-Induced Alcohol Craving in Recovering ...  -  Feb 28, 2007
Am J Psychiatry (subscription)OBJECTIVE: Ethanol blocks N-methyl-D-aspartic acid (NMDA) glutamate receptors. Increased NMDA receptor function may contribute to motivational disturbances

Calcium regulation of troponin and its role in the dynamics of ...  -  Mar 6, 2007
AJP-Regul Integr Comp Physiology (subscription)Kinetics of thin filament activation probed by fluorescence of N-{[2-(Iodoacetoxy)ethyl]-N-methyl}amino-7-nitrobenz-2-oxa-1, 3-diazole-labeled troponin I

Understanding the Role of Sigma-1 Receptors in Psychotic Depression  -  Mar 15, 2007
Psychiatric Times,Monnet FP, Debonnel G, de Montigny C (1992), In vivo electrophysiological evidence for a selective modulation of N-methyl-D-aspartate-induced neuronal

Erectile Dysfunction And Diabetes  -  Mar 18, 2007
Medical News Today (press release),Penile erection is a behavioral response that occurs in response to the administration of N-methyl-D-aspartic acid (NMDA) within the PVN. At the same time,

Pittsburgh patents  -  Mar 14, 2007
Pittsburgh Post Gazette,D-Serine's role as a neurotransmitter is important in the activation of the N-methyl-D-aspartate (NMDA) selective subtype of the glutamate receptor,

Thrombolysis After Stroke Benefits Men More Than Women  -  Mar 13, 2007
MedPage Today,1367 ischemic stroke patients were randomized to placebo or gavestinel, an antagonist of the glycine site of the N-methyl-D-aspartate receptor.

Clinical Update - Debio-9902 SR (ZT-1) Implant for Alzheimer's Disease  -  Mar 9, 2007
Drug Newswire (press release),The dual mode of action of DEBIO-9902 SR as a N-methyl-D-aspartate receptor antagonist and an AChE inhibitor, positions it as a third generation

Anti-Hebbian Long-Term Potentiation in the Hippocampal Feedback ...  -  Mar 1, 2007
Science Magazine (subscription)Hebb's postulate of associative learning, typically requires depolarization-dependent glutamate receptors of the NMDA (N-methyl-D-aspartate) subtype.

Medications helping Alzheimer's patients  -  Feb 27, 2007
Midland Daily News (subscription),Toward that end, cholinesterase inhibitors such as Aricept are now commonly prescribed for mild to moderate Alzheimer’s, while N-methyl D-aspartate (NMDA)

Hollis-Eden Pharmaceuticals Presents Additional Positive Data with ...  -  Feb 23, 2007
PipelineReview.com (press release),Rats were given the potent carcinogen N-methyl-N-nitrosourea to induce multiple breast tumors. Later in the experiment, animals with detected tumors were

Emerging Knowledge About Opioid Tolerance May Yield New Strategies ...  -  Feb 23, 2007
DG News...increases may find that overstimulation of the N-methyl-D-aspartate (NMDA) receptor is stymieing their approach and facilitating tolerance to opioids.

Waterborne Polyurethane Coatings Gaining in Popularity  -  Feb 21, 2007
Azom.comHowever, there are almost no polyurethane dispersions available today that do not contain N-methyl pyrrolidone (NMP). The responsible working group of the

Schizophrenic genes located  -  Feb 21, 2007
DrugResearcher.com,...glutamatergic signalling as well as being involved in the N-methyl-D-aspartic acid (NMDA) receptor-mediated synaptic plasticity, alterations of which

TECH WORLD: Forest Labs Demonstrating Strong Earnings Growth  -  Feb 20, 2007
Inside Futures,Namenda, its N-methyl-D-aspartate antagonist for the treatment of moderate to severe Alzheimer's disease; Benicar, an angiotensin receptor blocker for

TECH WORLD: Forest Labs Demonstrating Strong Earnings Growth  -  Feb 20, 2007
Optionetics,...the selective serotonin reuptake inhibitor for the treatment of major depression and generalized anxiety disorder; Namenda, its N-methyl-D-aspartate

Forest Laboratories Announces Rule 144 Sale by Executive Officer  -  Feb 15, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Seduce with Seafood 'All Fresh Seafood Recommends Edible ...  -  Feb 6, 2007
Emediawire (press release),Oysters, Clams and Mussels - These shellfish contain iron, zinc, iodine and the compounds D-aspartic acid and NMDA (N-methyl-D-aspartate).

Arbor Vita And NoNO To Present At 2007 International Stroke Conference  -  Feb 3, 2007
Medical News Today (press release),NA-1 is a compound that has been shown to inhibit the interaction between NMDA (N-methyl D-aspartate) receptors and PSD-95.

Javelin Pharmaceuticals Announces Results of FDA Meeting for Nasal ...  -  Jan 31, 2007
Epicos.com (press release),Ketamine, a non-opiate, is an N-methyl-D-aspartate ("NMDA") receptor antagonist that has been in clinical use for over 30 years as a general anesthetic.

Forest Laboratories, Inc. Reports Q3'07 Diluted Earnings Per Share ...  -  Jan 16, 2007
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl-D-aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate and severe Alzheimer's disease;

Forest Laboratories Announces Completion of Acquisition of Cerexa ...  -  Jan 12, 2007
PharmaLive.com (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Elevated Prenatal Homocysteine Levels as a Risk Factor for ...  -  Jan 1, 2007
Archives of General PsychiatryContext Elevated prenatal homocysteine level is a plausible risk factor for schizophrenia because of its partial antagonism of N-methyl-D-aspartate

Cognitive Training For Older Adults May Help Slow Decline Of Daily ...  -  Dec 25, 2006
Medical News Today (press release),...pharmacological agents (such as the cholinesterase inhibitors or N-methyl-D-aspartate receptor antagonists) would have additional treatment options.

Cognitive Training For Older Adults May Help Slow Decline Of Daily ...  -  Dec 25, 2006
Medical News Today (press release),...pharmacological agents (such as the cholinesterase inhibitors or N-methyl-D-aspartate receptor antagonists) would have additional treatment options.

Cerexa to Be Acquired by Forest Laboratories for $480 Million Plus ...  -  Dec 14, 2006
Drug Newswire (press release),Namenda(R) (memantine HCl), an N-methyl D- aspartate (NMDA)-receptor antagonist indicated for the treatment of moderate to severe Alzheimer's disease;

Plasma Cortisol and Progression of Dementia in Subjects With ...  -  Dec 6, 2006
Am J Psychiatry (subscription)Weiland NG, Orchinik M, Tanapat P: Chronic corticosterone treatment induces parallel changes in N-methyl-d-aspartate receptor subunit messenger RNA levels

Acamprosate for Alcohol Dependence: An Update for the Clinician  -  Dec 6, 2006
Focus (subscription)...inhibitory neurotransmitter, and the excitatory neurotransmitter, glutamate, which acts mainly through N-methyl-D-aspartate (NMDA) receptors (12, 13).

Oyster bisque: An aphrodisiac for the holiday  -  Dec 1, 2006
Korea Herald (subscription),...his team of US and Italian scientists released a study claiming that oysters are rich in the rare amino acids D-aspartic acid and N-methyl-D-aspartate.

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