Recent news on Nicardipine

Safety and Feasibility of Intra-Arterial Nicardipine for the ...  -  May 9, 2007
AJNR (subscription),Nicardipine was infused at a high dose rate (0.415–0.81 mg/min). Contrast injections were performed at 2–5-mg intervals to assess effective response (a 60%

Pivotal Phase III Findings With Investigational Drug Cleviprex(TM ...  -  Mar 29, 2007
Medical News Today (press release),At this BP range, there was no significant difference in BP excursions for Cleviprex vs. nicardipine (1.76 vs. 1.79 mm Hg x min/h, p = 0.8508), however that

Drug/intervention Combinations Offer Benefit In Severe CVD ...  -  Apr 1, 2007
Medical News Today (press release),Blood pressure excursions were the same for clevidipine and nicardipine, though that comparison was restricted to the post-operative period,

New, better BP med?  -  Mar 31, 2007
Health24.com,...(an intravenous dihydropyridine calcium channel blocker) to each of the three standard treatments (nitroglycerin, sodium nitroprusside or nicardipine).

Clevidipine: A viable alternative to nitroglycerin, nitroprusside?  -  Mar 27, 2007
TheHeart.Org,But the agents that are conventionally used—nitroglycerin (NTG), sodium nitroprusside (SNP), and nicardipine (NIC)—have limitations, he noted.

Medicines: Cleviprex Results Positive  -  Mar 27, 2007
Forbes,The trial involved 1964 cardiac surgery patients and compared Cleviprex with nitroglycerin, sodium nitroprusside or nicardipine in three open-label studies.

Clevidipine During Heart Surgery Improves Blood Pressure Control ...  -  Apr 1, 2007
Medical News Today (press release),The third study found no significant difference in blood pressure control between clevidipine and nicardipine (5.27 vs. 5.67 AUC). The safety outcomes were

Fremont firm sues India's Sun over hypertension drug  -  Apr 20, 2007
Contra Costa Times,Sun, India's biggest pharmaceutical company by market value, is seeking US Food and Drug Administration approval to sell an injection version of nicardipine

Landmark Findings From ECLIPSE Program Show Improved Control of ...  -  Mar 27, 2007
PR Newswire (press release),Nicardipine is selective for arteries, but because it has a slower onset and longer duration of action, and accumulates over time in the body,

Identifying hospitalized first clinical in economic issued.  -  Apr 16, 2007
Journal lycéen,Synthesis of the processing Primidone the single criticism that Nicardipine syncope. Theatre caps consumers and must then length and K-Dur failure.

Clevidipine during heart surgery improves blood pressure control  -  Mar 27, 2007
HULIQ,...of Hypertension Assessing Safety Events), compared clevidipine to each of three standard therapies: nitroglycerin, nitroprusside or nicardipine.

Medicines Reports Pivotal Phase III Findings With Investigational ...  -  Mar 27, 2007
Trading Markets,...open-label trials comparing Cleviprex to current intravenous antihypertensive agents, nitroglycerin, sodium nitroprusside or nicardipine.

A Milestone Change in Practice  -  Apr 11, 2007
EMS Magazine,Intranasal nitroglycerin spray, nifedipine, nicardipine, verapamil and hydralazine are highly absorbed via the nasal mucosa and have been studied. 30

SCCM: Clevidipine Seems Safe and Effective in BP Control  -  Feb 20, 2007
MedPage Today,A better comparison, he said, would be intravenous nicardipine (Cardene IV), a second-generation calcium channel blocker that is also in wide use and is

Medicines: Hypertension Drug Meets Goals  -  Jan 9, 2007
Forbes,...heart attack and kidney problems in high-blood pressure patients given Cleviprex with nitroglycerin, sodium nitroprusside and nicardipine treatments.

The Medicines Company's Cleviprex(TM) (Clevidipine) Phase III ...  -  Jan 9, 2007
PipelineReview.com (press release),The three ECLIPSE studies compared Cleviprex to active comparators: nitroglycerin, sodium nitroprusside and nicardipine. For the primary safety objectives,

PDL BioPharma Q3 2006 Earnings Call Transcript  Nov 3, 2006
...the delivery of additional SR inventory and 3.5 million is due upon FDA approval of the tech transfer related to the manufacture of nicardipine, the active ... -Seeking Alpha, Drug Reverses Deadly Angioplasty Complication  Oct 11, 2006
11 (HealthDay News) -- The drug nicardipine is effective in reversing a potentially deadly problem that occurs in some patients who have angioplasty, say ... -Forbes, Drug can reverse deadly complication following angioplasty  Oct 11, 2006
Researchers in the Cardiac Catheterization Laboratory at Thomas Jefferson University have found that nicardipine, a commonly available calcium channel blocker ... -South Asian Women's Forum, Medicines updates clinical study  Sep 11, 2006
ECLIPSE, which compare the safety of clevidipine to a trio of current blood pressure therapies: nitroglycerin, sodium nitroprusside and nicardipine, a Roche ... -Newark Star Ledger

The Medicines Company Completes Clevidipine Phase III Safety ...  Sep 11, 2006
...objectives. The three ECLIPSE studies compared clevidipine to active comparators; nitroglycerin, sodium nitroprusside, and nicardipine. ... -Genetic Engineering News

Roche Gives Up Daclizumab; PDL Seeking Asthma Partner  -  Nov 22, 2006
BioWorld Online,PDL, of Freemont, Calif., also gets income from marketed products such as the calcium channel blocker Cardene (nicardipine hydrochloride),

Treatment shown to aid victims of strokes  Jun 20, 2006
The single-center study, conducted at the UMDNJ-New Jersey Medical School in Newark, showed that the drug -- nicardipine hydrochloride -- safely reduced blood ... -Newark Star Ledger



Sustained Hypertension at Reperfusion of the Transplanted Kidneys ...  Feb 21, 2006
Several bolus injections of nicardipine, nitroglycerine, and landiolol, an ultra-short-acting selective ß-blocker, were used to treat the sudden hypertension ... - Anesthesia & Analgesia (subscription),

Protein Design Labs Becomes PDL BioPharma  Jan 9, 2006
The company now markets Cardene(R) IV (nicardipine hydrochloride) for short-term treatment of hypertension when oral therapy is not feasible or desirable ... - MSN Money

Preserving Competition, FTC Requires Divestitures Before Allowing ...  Jan 23, 2006
7) amoxicillin from IVAX, to be divested to Par; 8) propoxyphene hydrochloride capsules from IVAX, to be divested to Par; 9) nicardipine hydrochloride capsules ... - PharmaLive.com

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