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Recent news on Nolvadex


Upfront Femara® Reduces Risk of Early Recurrence of Breast Cancer  -  May 15, 2007
Cancer Consultants (press release),Previous reports have suggested that Femara is more effective than Nolvadex in preventing breast cancer recurrences in women with early stage hormone

Loeb & Loeb Continues To Bolster Intellectual Property Practice ...  -  Apr 26, 2007
Lawfuel (press release),Waddell has been involved in patent cases for high profile pharmaceuticals including Prozac, Paxil, and the breast cancer drug Nolvadex.

Tamoxifen Treatment and New-Onset Depression in Breast Cancer Patients  -  May 3, 2007
Psychosomatics (subscription)AstraZeneca Pharmaceuticals LP Nolvadex®: Tamoxifen Product Information. Wilmington, DE, 2005. Patten SB, Barbui C: Drug-induced depression: a systematic

Overall Approximately 3 Million Women in the US Are Living With ...  -  Apr 13, 2007
Genetic Engineering News (press release),In the past decade the regulatory authorities in US have approved five hormone-based therapies (Faslodex, Femara, Aromasin, Nolvadex and Arimidex),

Switching from Tamoxifen to Aromatase Inhibitor Improves Survival ...  -  Apr 11, 2007
Cancer Consultants (press release),...postmenopausal women with hormone-positive early breast cancer have improved survival when they switch from tamoxifen (Nolvadex®) to an aromatase agent.

Breast cancer death rate falling  -  Apr 11, 2007
Globe and Mail,And drugs including tamoxifen (trade named Nolvadex) and trastuzumab (Herceptin) are helping prevent recurrences. The new report, entitled Canadian Cancer

High court could take drug case  -  Mar 20, 2007
The News Journal,Zeneca agreed to pay Barr $21 million to settle its patent challenge, and gave Woodcliff Lake, NJ-based Barr the right to sell Nolvadex.

Breast Cancer Drugs  -  Mar 20, 2007
Minneapolis Star Tribune (subscription),Nolvadex (tamoxifen): It is effective in the two-thirds of breast cancers that are estrogen-receptive - where the proliferation of cancer cells is fueled by

Supreme Court seeks government views in tamoxifen patent settlement  -  Mar 19, 2007
MarketWatch...set the generic drug company up for a six month head start in selling a generic version of Zeneca's tamoxifen drug, known as Nolvadex.

Women's Cancer Drug Maker Stocks Mixed on New Breast Cancer Drug  -  Mar 15, 2007
CanadianBusiness.com,Other FDA-approved breast cancer treatments include Taxotere from Sanofi-Aventis SA, Femara from Novartis AG, Nolvadex and Arimidex from AstraZeneca PLC,

Studies Examine Breast Cancer Prevention, Efficacy Of Family ...  -  Feb 27, 2007
Medical News Today (press release),The drug was sold under the brand name Nolvadex by AstraZeneca and is now marketed by several generic drugmakers. Under current treatment guidelines,

Poor Compliance with Adjuvant Nolvadex® Reported  -  Jan 29, 2007
Cancer Consultants (press release),Until recently the most commonly used drug was Nolvadex. There is recent evidence that Femara (letrozole) and Arimidex® (anastrozole) are more effective

Tamoxifen Prevents ER-positive Breast Cancer Years Following ...  -  Feb 22, 2007
Cancer Consultants (press release),According to an article recently published in the Journal of the National Cancer Institute, treatment with tamoxifen (Nolvadex®) can significantly reduce

Further Evidence Supporting a Switch to Aromasin® Following Two to ...  -  Feb 16, 2007
Cancer Consultants (press release),Aromatase inhibitors have activity in patients who have failed Nolvadex. Clinical trials have suggested that aromatase inhibitors may be superior to

50 jobs to be cut at plant in Bear  -  Feb 22, 2007
The News Journal,The plant's workers package 10 drugs and manufacture three, including Seroquel, a drug for schizophrenia and bipolar disorder, and Arimidex and Nolvadex,

Further Evidence Supporting a Switch to Aromasin® Following Two to ...  -  Feb 14, 2007
Cancer Consultants (press release),...and overall survival if they switch to the aromatase agent Aromasin® (exemestane) after two to three years of treatment with tamoxifen (Nolvadex®).

Switching Breast Cancer Drug Increases Survival  -  Feb 12, 2007
Lex 18,Italian researchers pooled results from two studies comparing women who remained on tamoxifen (Nolvadex) for five years to women who started out on

Faslodex® Benefits Subset of Women Resistant to Aromatase Inhibitors  -  Feb 1, 2007
Cancer Consultants (press release),Historically, the most common hormonal treatment for estrogen receptor-positive breast cancer was tamoxifen (Nolvadex®). Tamoxifen blocks estrogen receptors

Aromasin® Compromises Bone Health in Breast Cancer Patients  -  Jan 31, 2007
Cancer Consultants (press release),Researchers associated with the Intergroup Extemestane Study (IES) have reported that women with breast cancer who switch from Nolvadex® (tamoxifen) to

Aromasin® Compromises Bone Health in Breast Cancer Patients  -  Jan 26, 2007
Cancer Consultants (press release),According to an article recently published in the Lancet, women with breast cancer who switch from tamoxifen (Nolvadex®) to Aromasin® (exemestane) have an

Studies Examine Breast Cancer Prevention, Efficacy of Family ...  -  Feb 23, 2007
Kaiser network.org,The drug was sold under the brand name Nolvadex by AstraZeneca and is now marketed by several generic drugmakers. Under current treatment guidelines,

Newer breast cancer drugs save lives, study finds  -  Feb 13, 2007
CNNIt is sold by AstraZeneca under the name Nolvadex but now is marketed by several generic drug makers. Breast cancer is the second leading cause of cancer

MammaPrint® Approved to Predict Recurrences in Breast Cancer  -  Feb 13, 2007
Cancer Consultants (press release),...for patients with newly diagnosed Stage I or II, node-negative, estrogen-receptor positive breast cancer who will be treated with tamoxifen (Nolvadex®).

Early switch to aromatase inhibitor ups survival, study says  -  Feb 12, 2007
Pharma Times (subscription),Despite this risk, tamoxifen, which is sold as Nolvadex by AstraZeneca although there are several generic versions on the market and another drug in this

Switching to newer breast cancer drugs boosts survival  -  Feb 12, 2007
Cancerfacts.com,Tamoxifen (Nolvadex®) and aromatase inhibitors such as anastrozole (Arimedex®) and letrozole (Femara®) reduce estrogen levels in the blood.

Senate to consider boost to generics  -  Feb 9, 2007
The News Journal,In 1993, Zeneca, an AstraZeneca predecessor, paid a reported $21 million to settle Barr's challenge over the patent for Zeneca's Nolvadex breast cancer drug

AstraZeneca to eliminate 3000 jobs by 2010  -  Feb 2, 2007
The News Journal,...crew on its third shift, also manufactures Seroquel, a treatment for schizophrenia and bipolar disorder, and breast cancer drugs Arimidex and Nolvadex.

Nolvadex® Appears to Prevent Breast Cancer Years Following ...  -  18 Jan 2007
Cancer Consultants (press release),According to results recently presented at the 2006 annual San Antonio Breast Cancer Symposium, Nolvadex® (tamoxifen) appears to reduce the risk of

Restoring Tamoxifen Sensitivity In Resistant Breast Cancer Cells  -  18 Jan 2007
Medical News Today (press release),The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used

Oncotype DX™ Accurately Measures Estrogen Receptor Status in Node ...  -  Jan 9, 2007
Cancer Consultants (press release),This trial included 297 node-negative, ER-positive breast cancer patients who had already received treatment with Nolvadex® (tamoxifen) in the prior NSABP

OncotypeDX™ Accurately Measures Estrogen Receptor Status in Node ...  -  Dec 20, 2006
Cancer Consultants (press release),1] In addition, use of OncotypeDX™ to assess ER and progesterone receptor (PR) status provided information about prognosis and response to Nolvadex®

Compound 'jump-starts' breast-cancer drug  -  Dec 21, 2006
United Press InternationalAccording to a mouse study done by investigators from the National Cancer Institute, tamoxifen -- sold under the brand name Nolvadex -- appears to get a

Surgery Alone May Be Not Effective Enough in High-Grade DCIS  -  Dec 20, 2006
Cancer Consultants (press release),In 2000, adjuvant Nolvadex® (tamoxifen) was allowed. The median follow-up was 5.4 years. Among patients with low or intermediate-grade DCIS,

OncotypeDX™ Accurately Measures Estrogen Receptor Status in Node ...  -  Dec 8, 2006
Cancer Consultants (press release),1] In addition, use of OncotypeDX™ to assess ER and progesterone receptor (PR) status provided information about prognosis and response to Nolvadex®

Restoring tamoxifen sensitivity in resistant breast cancer cells  -  Dec 22, 2006
Hindu,The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used

Compound 'jump-starts' breast-cancer drug  -  Dec 21, 2006
United Press InternationalAccording to a mouse study done by investigators from the National Cancer Institute, tamoxifen -- sold under the brand name Nolvadex -- appears to get a

Anabolic steroids for sale  -  Dec 3, 2006
PR Inside (Pressemitteilung),...descriptions, and forum. how to buy real steroids through mail order, sustanon, sustenon, cypionate, propionate, enanthate, proviron, nolvadex, clomid,

Surgery Alone May Be Not Effective Enough in High-Grade DCIS  -  Dec 20, 2006
Cancer Consultants (press release),In 2000, adjuvant Nolvadex® (tamoxifen) was allowed. The median follow-up was 5.4 years. Among patients with low or intermediate-grade DCIS,

Surgery Alone May Be Not Effective Enough in High-grade DCIS  -  Dec 18, 2006
Cancer Consultants (press release),In 2000 adjuvant Nolvadex® (tamoxifen) was allowed. Among patients with low- or intermediate-grade DCIS, the five-year risk of cancer recurrence in the

Similar Quality of Life with Evista® and Nolvadex® for ...  Oct 23, 2006
...to an article published in Obstetrical and Gynecological Survey, five-year results indicate that side effects are similar for Nolvadex® (tamoxifen) and Evista ... -Cancer Consultants (press release), Evista® and Nolvadex® for Breast Cancer Prevention Have Similar ...  Oct 19, 2006
Researchers affiliated with the National Surgical Adjuvant Breast and Bowel Project Study of Nolvadex® (tamoxifen) and Evista (raloxifene) (STAR P-2 Trial ... -Cancer Consultants (press release), Longer Follow-Up Confirms Femara® More Effective Than Nolvadex® ...  Oct 17, 2006
Researchers affiliated with the BIG-98 trial comparing Femara® (letrozole) to Nolvadex® (tamoxifen) have reported that longer follow-up confirms the ... -Cancer Consultants (press release), FDA advisory panel recommends adding warning label to Tamoxifen  Oct 19, 2006
...have side effects including uterine cancer in women who have not had hysterectomies and blood clots -- was sold under the brand name Nolvadex by AstraZeneca ... -News-Medical.net, Breast-Cancer Patients Need Data on Risk of Relapse, Panel Says  Oct 18, 2006
The FDA approved tamoxifen in 1977, and UK-based AstraZeneca Plc originally marketed it as Nolvadex. The company stopped selling ... -Bloomberg Breast cancer therapy may require genetic tests before tamoxifen  Oct 18, 2006
The FDA approved tamoxifen, originally sold as UK-based AstraZeneca's Nolvadex, in 1977 to treat breast cancer, and later cleared it to help reduce cancer ... -Dallas Morning News (subscription), Panel tells FDA Tamoxifen label should add recurrence risk  Oct 18, 2006
The agency first approved tamoxifen under the brand name Nolvadex in 1977 by then-manufacturer Zeneca Pharmaceuticals, which later merged with Astra to form UK ... -MarketWatch Four-year Results Continue to Show Superior Outcomes with Femara® ...  Oct 16, 2006
...up continue to indicate that treatment with Femara® (letrozole) significantly reduces the risk of cancer recurrences compared to Nolvadex® (tamoxifen) in ... -Cancer Consultants (press release), Medicare drug benefit expands cancer-drug access  Sep 17, 2006
As an example, the brand-name version of cancer-fighting tamoxifen, Nolvadex, is covered by 29% of plans, but the generic version is covered in 100% of ... -MarketWatch

75% of Cancer Drugs Are Covered Under Medicare Prescription Drug ...  Sep 20, 2006
For example generic tamoxifen is covered by 100% of stand-alone prescription drug plans and nearly 100% of integrated drug plans, but Nolvadex -- the brand ... -Kaiser network.org

US Court of Appeals Denies Rehearing Request in Dismissal of ...  Sep 18, 2006
...and AstraZeneca entered into an agreement that resulted in the distribution by Barr of a more affordable version of AstraZeneca's Nolvadex® (Tamoxifen Citrate ... -Yahoo! News

AstraZeneca Officially Opens Two Major Scientific Laboratories, As  Sep 18, 2006
...upon AstraZeneca’s successful heritage in oncology, including the discovery and development of important cancer medicines such as Nolvadex, Zoladex, Arimidex ... -WebWire

How to Manage Hot Flashes as a Cancer Patient  Sep 1, 2006
Breast cancer patients receiving hormone therapies – Drugs such as Nolvadex ® (tamoxifen) or aromatase inhibitors such as Arimidex ® (anastrozole) can ... -CancerWise

Addition of Gemzar® to Paraplatin® Improves Progression-Free ...  Sep 20, 2006
In addition, anti-estrogens such as Nolvadex® (tamoxifen) have activity in women with recurrent ovarian cancer and more recently monoclonal antibody therapy ... -Cancer Consultants

Charlotte Observer probe finds steroid dangers ignored in NFL  Aug 26, 2006
Wadler's report said Steussie got prescriptions from Shortt that day for testosterone with DHEA; androstenedione; and the anti-estrogens Nolvadex and Clomid. ... -San Jose Mercury News

Congressman disputes NFL's contention about steroids  Sep 8, 2006
Waxman also noted from the Observer report that a player received the anti-estrogens Nolvadex and Clomid, which weren't on the NFL's banned list when Shortt ... -San Jose Mercury News

On file: Steroids' risks, ravages  Aug 26, 2006
...said Steussie got prescriptions from Shortt the day of the pep rally for testosterone with DHEA; androstenedione; and the anti-estrogens Nolvadex and Clomid. ... -Charlotte Observer

Report is snapshot of doping in NFL  Aug 27, 2006
Houston, site of the Super Bowl, Steussie got prescriptions from Shortt for testosterone with DHEA; androstenedione; and the anti-estrogens Nolvadex and Clomid ... -News & Observer

letter to NFL chief rejects steroids claim  Sep 8, 2006
Waxman also noted that a player received the anti-estrogens Nolvadex and Clomid, which weren't on the NFL's banned list when Shortt was treating Carolina ... -Charlotte Observer

Researchers Discover Method in Mice to Restore Tamoxifen ...  -  Dec 11, 2006
National Institutes of Health (press release)The widely used breast cancer drug tamoxifen (Nolvadex®), which can become less effective over time, might retain its full strength indefinitely if used

Mid-Treatment Breast Cancer Switch to Aromatase Inhibitor Boosts ...  -  Nov 17, 2006
MedPage Today,They analyzed the Austrian Breast and Colorectal Cancer Study Group (ABCSG), Arimidex-Nolvadex (ARNO 95), and the Italian Tamoxifen Anastrozole (ITA)

Anabolic steroids for sale  -  Dec 3, 2006
PR Inside (Pressemitteilung),...descriptions, and forum. how to buy real steroids through mail order, sustanon, sustenon, cypionate, propionate, enanthate, proviron, nolvadex, clomid,

Women With Early Breast Cancer are More Likely to Remain Cancer ...  -  Nov 16, 2006
campus med,...'ARIMIDEX', 'CASODEX', 'FASLODEX', 'NOLVADEX', 'ZOLADEX', 'TOMUDEX', and 'IRESSA' are trademarks, the property of the AstraZeneca group of companies.

Drug Switch Ups Breast Cancer Survival  -  Nov 17, 2006
WebMDJonat's team combined data from three studies of postmenopausal women who, after breast cancercancer surgery, took tamoxifen (brand name, Nolvadex) to

Scottish women with HR+ breast cancer taking tamoxifen can now ...  -  Nov 13, 2006
PharmaLive.com (press release),Arimidex-Nolvadex (ARNO) 95 and Italian Tamoxifen Arimidex (ITA) trials, designed to assess whether changing treatment from tamoxifen to Arimidex after

Aromatase Inhibitors Declared Superior To Tamoxifen In The ...  Aug 3, 2006
NOLVADEX® (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal women following ... -Medical News Today

Aromatase Inhibitors Declared Superior to Tamoxifen in the ...  Aug 1, 2006
About Tamoxifen NOLVADEX(R) (tamoxifen citrate) is approved for the adjuvant treatment of node-positive and node-negative early breast cancer in postmenopausal ... -PR Newswire

US agency donates medicines to Morocco  Aug 11, 2006
...in a precarious situation. Spurred by the Operation USA, the donation included 1 650 000 tablets of Nolvadex. Operation USA, a non ... -African News Dimension (subscription)

A drug with preventive effects may also have downsides  Aug 1, 2006
Another study this year found that raloxifene was as effective at preventing breast cancer as tamoxifen (Nolvadex), the standard treatment; the two drugs may ... -Jackson Hole Star-Tribune

Cause of ALS yet unknown; cure is far off  Aug 20, 2006
...numerous medications for their usefulness in treating ALS, including the antibiotic minocycline (Minocin), the breast-cancer drug tamoxifen (Nolvadex), the HIV ... -Fort Wayne Journal Gazette

Newer breast cancer drug seen safer than tamoxifen  Aug 2, 2006
The study was funded by AstraZeneca, which developed both Arimidex and tamoxifen (Nolvadex), although the latter agent has been available in a generic form for ... -Reuters.uk

Daily Briefing  Aug 2, 2006
AstraZeneca said it would stop making tamoxifen, known by its brand name Nolvadex, in April because generic versions cut sales. ... -The News Journal

Tamoxifen: not for everyone  Jul 26, 2006
...in 1998 by the US Food and Drug Administration to help prevent breast cancer in women at high risk for the disease, "Tamoxifen [brand named Nolvadex] has been ... -Health24.com

Drug Found to Be Useful Only for Women at Greatest Risk  Jul 27, 2006
That study, for which LRMC and Watson Clinic enrolled patients, found raloxifene (Evista) as effective as tamoxifen (Nolvadex) in reducing postmenopausal ... -The Ledger

Taxotere® plus Iressa® Provides Impressive Anticancer Responses ...  Jul 20, 2006
...who achieved an anticancer response to the Taxotere/Iressa regimen continued to receive Iressa as a single agent or in combination with Nolvadex® (tamoxifen). ... -Cancer Consultants

Nolvadex® and Evista® Offer Similar Quality of Life  Jun 27, 2006
According to results published in the Journal of the American Medical Association, use of Nolvadex® (tamoxifen) or Evista® (raloxifene) to reduce breast ... -Cancer Consultants

Initial Report of Evista® Breast Cancer Prevention Trial ...  Jun 22, 2006
The results of the National Surgical Adjuvant Breast and Bowel Project Study of Nolvadex® (tamoxifen) and Evista (raloxifene) (STAR P-2 Trial) for prevention ... -Cancer Consultants

Arimidex® Gains Full Approval For Early Breast Cancer  Jun 30, 2006
Arimidex is currently the only aromatase inhibitor that has demonstrated improved disease-free survival over Nolvadex® (tamoxifen) in the primary adjuvant ... -Cancer Consultants

Priority Review Granted for Femara®  Jun 30, 2006
...of breast cancer in postmenopausal women who have completed 5 years (or are within 3 months of completion)of treatment with Nolvadex® (tamoxifen), as well as ... -Cancer Consultants

Gene Mutations Not Linked with Risk of Blood Clots in Breast ...  Jul 14, 2006
Breast and Bowel Project (NSABP) Breast Cancer Prevention Trial (P-1) began in 1992, with the goal of determining whether tamoxifen (Nolvadex®) could reduce ... -Cancer Consultants

Prior Chemotherapy Does Not Compromise Benefit of Arimidex® in ...  Jun 30, 2006
...with the ATAC trial (anastrozole and tamoxifen, alone or in combination), a large trial that compared Arimidex to tamoxifen (Nolvadex®) in postmenopausal ... -Cancer Consultants

Medical Edge: Study compares breast-cancer drugs  Jul 8, 2006
This four-year study, with nearly 20,000 women participating, compared the effectiveness of drugs tamoxifen (Nolvadex) and raloxifene (Evista) in reducing ... -Bryan College Station Eagle

New UK licence indication for Arimidex (anastrozole) extends ...  Jul 12, 2006
...was based on data from three key international trials – the Austrian Breast & Colorectal Cancer Study Group (ABCSG) 8, the Arimidex-Nolvadex (ARNO) 95 and ... -PharmaLive.com



Switching to Arimidex® Reduces Need for Invasive Diagnostic ...  Mar 9, 2006
Among postmenopausal breast cancer patients with uterine abnormalities related to Nolvadex® (tamoxifen), switching to the aromatase inhibitor Arimidex ... - Cancer Consultants

Thwarting further breast cancer  Mar 15, 2006
After the surgery, I got radiation treatments, and I took Nolvadex. What are the chances that it will come back? ... You had two of them -- radiation and Nolvadex. ... - Sarasota Herald-Tribune

Clodronate® in Early Breast Cancer May Reduce Risk of Developing ...  Mar 21, 2006
...trial included 1,069 patients with early breast cancer (stages I-III) who underwent surgery, radiation therapy, chemotherapy, and Nolvadex® (tamoxifen) if ... - Cancer Consultants

Tamoxifen Effective in Premenopausal Women with Hormone-Positive ...  Mar 9, 2006
According to an early on-line article published in the Journal of Clinical Oncology, the anti-estrogen agent tamoxifen (Nolvadex®) following chemotherapy ... - Cancer Consultants

AlphaB-crystallin protein linked to aggressive breast cancer  Apr 2, 2006
..." Currently, we don't have any targeted treatments like Tamoxifen ( Nolvadex ) or Trastuzumab ( Herceptin ) for the aggressive type of breast tumors that ... - Xagena.it

A 62-Year-Old Woman With a New Diagnosis of Breast Cancer  Mar 21, 2006
40. The Austrian Breast Cancer Study Group 8/Arimidex-Nolvadex 95 (ABCSG8/ARNO95) trial randomized 3223 women who had received 2 years of adjuvant tamoxifen to ... - Journal of American Medical Association (subscription)

Lilly's Evista Data Likely Positive, Market Limited  Mar 24, 2006
Anderson pointed out that AstraZeneca ultimately gave up on its attempts to create a breast cancer prevention market for tamoxifen, also known as Nolvadex. ... - Forbes

Taxotere®/Platinol®/Herceptin® Effective in Locally Advanced ...  Mar 22, 2006
...surgery, followed by subsequent chemotherapy including Adriamycin® (doxorubicin) and Cytoxan® (cyclophosphamide), radiation therapy and Nolvadex® (tamoxifen ... - Cancer Consultants

Take Your Pills, All Your Pills  Mar 11, 2006
AstraZeneca, which sells tamoxifen under the brand name Nolvadex and another breast cancer drug, Arimidex, helped pay for a meeting of a group of cancer ... - Gadsden Times (subscription)


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