Recent news on Paclitaxel

Royal Bank Of Canada Q2 Profit Up 14% - Quick Facts [RY]  -  25 May 2007
RTT News,In addition, new data from the Phase 1b trial of AP23573 combined with the chemotherapy, paclitaxel, in patients with a broad range of solid tumors also

AUA 2007 Plenary Session: SIU Lecture “What is New in the ...  -  25 May 2007
UroToday,Paclitaxel with carboplatin for regionally advanced disease showed 5 year survival of 40%, and holds promise. Molecular markers are numerous,

We’ll hire you elsewhere, say Conor Med bosses  -  25 May 2007
Athlone Advertiser,The shock announcement comes after the company was forced to discontinue supplying its product, CoStar cobalt chromium paclitaxel-eluting coronary stent,

Integrated BioPharma Retains Financial Advisor  -  25 May 2007
Primenewswire (press release),Its pharmaceutical business operates a cGMP facility for the production and sale of Paclitaxel and related drugs and provides technical services through its

Boston Scientific Receives CE Mark For TAXUS Liberte Long ...  -  May 23, 2007
Trading Markets,...(BSX | charts | news | PowerRating) on Thursday revealed the receipt of the CE Mark for its TAXUS Liberte Long paclitaxel-eluting coronary stent system.

Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting ...  -  Apr 26, 2007
PharmaLive.com (press release),The treatment arm enrolled patients with a synthetic bypass graft plus the Vascular Wrap(TM) paclitaxel-eluting mesh and the control arm enrolled patients

Sonus Pharmaceuticals Highlights Progress and Reports First ...  -  May 10, 2007
PharmaLive.com (press release),The discussion will include an overview of the progress with the Company's first two oncology product candidates, TOCOSOL(R) Paclitaxel and TOCOSOL

Boston Scientific Announces Schedule for EuroPcr 2007  -  May 15, 2007
PR Newswire (press release),Additional data will provide insight into the performance of our market-leading TAXUS(R) paclitaxel-eluting stent systems as well as our new

Bioxel Expands its Commercial Footprint in Europe  -  May 1, 2007
Web Services Journal,..."This objective requires systematic registration and approval of our paclitaxel drug master file (DMF) on behalf of our pharmaceutical clients in countries

Approvals: Herceptin, Reyataz, and Peg-Intron  -  May 21, 2007
Medscape (subscription)In the United States, trastuzumab is indicated for use alone in chemotherapy-experienced patients and with paclitaxel in chemotherapy-naive patients for the

Registries Confirm Worse Outcome When Drug-Eluting Stents Are Used ...  -  May 9, 2007
MedPage Today,For the paclitaxel-eluting (Taxus) stent, the standard use definition was de novo lesions of 28 mm or less, with a reference diameter of 2.5 mm to 3.75 mm

Conor Medsystems, LLC Reports COSTAR II Pivotal Drug-Eluting Stent ...  -  May 7, 2007
WebWire (press release),Menlo Park, CA - Citing issues related to potentially sub-optimal therapeutic dosing of paclitaxel, Conor Medsystems, LLC has concluded that the COSTAR II

Conor Medsystems, LLC Reports COSTAR II Pivotal Drug-Eluting Stent ...  -  May 7, 2007
Angioplasty.Org,The COSTAR II trial compared the CoStar® stent with the Taxus Express(2) paclitaxel drug-eluting stent, and was designed to demonstrate non-inferiority at

UK licence for breast cancer drug  -  May 10, 2007
BBC News,In trials, breast cancer patients who took Avastin and paclitaxel went an average of 13 months without their cancer growing, compared with an average of 6.7

Use of coronary stents declines, Toronto study shows  -  May 17, 2007
Vancouver Sun (subscription),The drug coated stents accounted for 69.7 per cent of stents used, down from 90 per cent last June. Boston Scientific uses Angiotech's paclitaxel in its

Two-year data for Angiotech's Vascular Wrap Paclitaxel-Eluting ...  -  26 Apr 2007
PharmaLive.com (press release),The treatment arm enrolled patients with a synthetic bypass graft plus the Vascular Wrap(TM) paclitaxel-eluting mesh and the control arm enrolled patients

Two-year data for Angiotech's Vascular Wrap(TM) Paclitaxel-Eluting ...  -  26 Apr 2007
PR-Inside.com (Pressemitteilung),The treatment arm enrolled patients with a synthetic bypass graft plus the Vascular Wrap(TM) paclitaxel-eluting mesh and the control arm enrolled patients

Cancer patients dig deep to pay for new drugs  -  26 Apr 2007
Globe and Mail,Paclitaxel protein-bound (Abraxane): Uses albumin, a natural protein found in the body, to deliver high concentrations of paclitaxel into metastatic breast

Boston Scientific Announces Completion of Enrollment in Landmark ...  -  26 Apr 2007
PR Newswire (press release),TAXUS(R) Express2(TM) paclitaxel-eluting coronary stent system, versus the current clinical standard of coronary artery bypass graft (CABG) surgery.

Integrated BioPharma Reports Third Quarter Results  -  26 Apr 2007
Primenewswire (press release),Its pharmaceutical business operates a cGMP facility for the production and sale of Paclitaxel and related drugs and provides technical services through its

CuraGen Reports First Quarter 2007 Financial Results and Updated ...  -  26 Apr 2007
Earthtimes.orgPreliminary Phase Ib/II results of intravenous belinostat in combination with carboplatin and paclitaxel for advanced ovarian cancer to be presented in a

Cancer-Fighting Drug Found in Dirt  -  Apr 24, 2007
FOX NewsScientists originally isolated the drug paclitaxel — now commonly known as Taxol — in 1967 from the bark of Pacific yew trees (Taxus brevifolia) in a forest

Inactivation of specific tumour genes may increase effectiveness ...  -  Apr 23, 2007
Public Health Genetics Unit Newsletter,87 genes were identified which, when inactivated in this way, made the cells sensitive to paclitaxel concentrations up to 1000-fold lower than those

Does The Addition Of Paclitaxel To Bare Metal Mesh Stents Improve ...  -  Apr 11, 2007
Medical News Today (press release),Paclitaxel is an anti-cancer agent that promotes the polymerization of tubulin and inhibits the disassembly of microtubules which in turn causes cell death

TODAY ON PHARMALIVE.COM  -  Apr 19, 2007
PharmaLive.com (press release),The first of two pre-clinical studies investigating mechanistic aspects of chemotherapy induced angiogenesis showed for the first time that nab-paclitaxel,

Angiotech Initiates US Pivotal Trial for the Vascular Wrap(TM ...  -  Mar 28, 2007
Drug Newswire (press release),Based on the strength of this two-year data, Angiotech submitted an application for a CE Mark for its Vascular Wrap(TM) paclitaxel-eluting mesh / ePTFE

Abraxis BioScience Presents Pre-Clinical Findings That Support ...  -  Apr 19, 2007
PharmaLive.com (press release),This provides concrete support for the earlier hypothesis that higher levels of SPARC protein may lead to enhanced antitumor effect of nab-paclitaxel,

Telik Reports Positive New Telcyta Preclinical Data at American ...  -  Apr 18, 2007
PharmaLive.com (press release),One series of studies focused on cellular and molecular correlates of synergistic cancer cell growth inhibition caused by TELCYTA, carboplatin or paclitaxel

Telik Reports Positive New TELCYTA Preclinical Data at American ...  -  Apr 17, 2007
PR-Inside.com (Pressemitteilung),...on cellular and molecular correlates of synergistic cancer cell growth inhibition caused by TELCYTA, carboplatin or paclitaxel alone and in doublet and

Adherex Announces Two Presentations of ADH-1 Data at 2007 American ...  -  Apr 17, 2007
PharmaLive.com (press release),This study explored in vitro and in vivo anti-tumor activity of ADH-1 alone, paclitaxel alone and ADH-1 and paclitaxel in combination using ovarian cell

Supergen Sells Select Non-Core Assets to Intas  -  Apr 20, 2007
PR Newswire (press release),Mitomycin and Paclitaxel rights sold for $1.2 million DUBLIN, Calif., April 20 /PRNewswire-FirstCall/ -- SuperGen Inc. (Nasdaq: SUPG) today announced that

Taxane Use And Dose-Dense Scheduling May Benefit Patients With ...  -  Apr 14, 2007
Medical News Today (press release),To date, no study has demonstrated superiority with a specific taxane (paclitaxel vs. docetaxel vs. albumin-bound paclitaxel); therefore this characteristic

Get the latest news direct to your desktop  -  Apr 18, 2007
PipelineReview.com (press release),Patients received standard doses of carboplatin and paclitaxel and one of four doses of TELCYTA (400, 500, 750 or 1000 mg/m2) for a planned course of four

The code that could unlock cancer  -  Apr 19, 2007
CNN InternationalCommon symptoms of paclitaxel and other chemotherapy treatments include nausea, loss of appetite, hair loss and joint pain.

Data supporting three Antisoma programmes presented at AACR  -  Apr 16, 2007
PharmaLive.com (press release),AS1404-Avastin-paclitaxel triple combination highly effective Antisoma's scientists have for the first time evaluated a triple combination of the Company's

Supergen Sells Select Non-Core Assets to Intas  -  Apr 20, 2007
PharmaLive.com (press release),...that it signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2 million.

Data supporting three Antisoma programmes presented at AACR  -  Apr 16, 2007
PipelineReview.com (press release),These observations build on previous xenograft findings showing a synergistic effect with an AS1404-paclitaxel combination. That effect translated into a

Thermo Fisher Scientific RNA Technology Enables Discovery in ...  -  Apr 18, 2007
GenomicsProteomics.com (press release),He found that when certain genes were silenced, the chemotherapy drug paclitaxel (Taxol) was dramatically more effective in destroying the cancer cells.

Massive Gene Screening Points Way To More Effective Chemotherapy  -  Apr 15, 2007
Medical News Today (press release),Next, the drug paclitaxel was added to each well for two days. By examining the survival of the cells in each well, the researchers determined which genes

Cell Therapeutics, Inc. (CTI) Announces XYOTAX(TM) Has Fast Track ...  -  Apr 12, 2007
Medical News Today (press release),The trial will study XYOTAX in combination with carboplatin versus paclitaxel/carboplatin in female NSCLC patients with performance status of 0,

Cancer Genes Linked to Chemotherapy Sensitivity  -  Apr 12, 2007
Genetic Engineering News (press release),Researchers have discovered 87 genes that seem to affect the sensitivity of human cancer cells to Paclitaxel. When the researchers blocked the action of

Antisoma says successfully tests cancer drugs  -  Apr 16, 2007
Hemscott,It said its triple drug combination AS1404-Avastin-paclitaxel had a powerful anti-tumour effect in a human lung cancer xenograft model.

Bioxel Pharma: Results for Fiscal 2006  -  Mar 29, 2007
CCNMatthews (press release),..."We pursued our new taxane development program, thereby moving closer to the commercial scale-up of docetaxel and semi-synthetic paclitaxel.

SuperGen Sells Drugs for $1.2 Million  -  Apr 20, 2007
Houston Chronicle,Pharmaceutical company SuperGen Inc. said Friday it will the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for $1.2

CINVENTION and Relisys Medical Devices Enroll First Patients in ...  -  Apr 13, 2007
PharmaLive.com (press release),The coating itself is made out of non-thrombogenic glassy carbon, the bio-availability of paclitaxel is nearly hundred percent and, additionally,

SuperGen sells drugs for $1.2 million  -  Apr 20, 2007
ABCmoney.co.uk,...(AP) - Pharmaceutical company SuperGen Inc. said Friday it will the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals Ltd. for

Telik Shares Rise on Cancer Drug Data  -  Apr 17, 2007
Forbes,In a Phase II clinical trial, patients taking Telcyta, along with chemotherapy and paclitaxel, lived for an average of 6.9 months without disease

Avastin Approved in Europe for First Line Treatment of Women with ...  -  Mar 29, 2007
PipelineReview.com (press release),About the E2100 study Study E2100 was the first Phase III study set to evaluate Avastin in combination with paclitaxel versus paclitaxel alone for the

Supergen (SUPG) Announces Sale of Select Non-Core Assets to Intas  -  Apr 20, 2007
StreetInsider.com (subscription),SuperGen Inc. (Nasdaq: SUPG) has signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals

Market Report -- In Play (SUPG)  -  Apr 20, 2007
MSN MoneyCo announces it signed a definitive agreement to sell the rights to anticancer agents mitomycin and paclitaxel to Intas Pharmaceuticals for $1.2 mln.

Revolution in cancer treatment  -  Apr 12, 2007
Belfast Telegraph,Taxol - also known as paclitaxel - is also used to treat ovarian cancer and advanced breast cancer. Side effects include fatigue, nausea, numbness and bone

Market Report -- In Play (TELK)  -  Apr 17, 2007
MSN MoneyOne series of studies focused on cellular and molecular correlates of synergistic cancer cell growth inhibition caused by Telcyta, carboplatin or paclitaxel

Telik reports promising data from cancer treatment, shares up  -  Apr 17, 2007
ReutersThe biopharmaceutical company said a combination of its drug Telcyta with carboplatin and paclitaxel improved survival in responding patients.

Viventia Biotech announces results of Proxinium antibody in ...  -  Apr 22, 2007
News-Medical.net,The combination of Proxinium with cisplatin, carboplatin, paclitaxel, 5-fluorouracil, and docetaxel resulted in a significant additive cytotoxic effect (p

A matter of focus  -  25 Feb 2007
Business Standard,The company has recently secured United States Food and Drug Authority (USFDA) approvals for its carboplatin and paclitaxel injectables, and is seeking more

Avastin Receives Positive Opinion in Europe for First-line ...  -  Feb 23, 2007
PharmaLive.com (press release),About the E2100 study This is the first Phase III study to evaluate Avastin in combination with paclitaxel for first-line treatment of patients with locally

Second Generation Conor CoStar Drug-Eluting Stent Data to be ...  -  Feb 23, 2007
Angioplasty.Org,These reservoirs are then filled with a bioabsorable polymer that elutes the drug paclitaxel, which prevents restenosis. After six months, not only has the

Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary ...  -  Feb 12, 2007
New England Journal of Medicine (subscription),The 4-year rates of target-lesion revascularization were markedly reduced in both the sirolimus-stent group and the paclitaxel-stent group, as compared with

Opto Circuits subsidiary Eurocor GmbH launches "DIOR"  -  Feb 20, 2007
Equity Bulls,Clinical evidence trials, too, concluded that the treatment with Paclitaxel eluting balloon dilation catheters significantly reduce the incidence of

Stent Thrombosis in Randomized Clinical Trials of Drug-Eluting Stents  -  Feb 12, 2007
New England Journal of Medicine (subscription),...involving 878 patients treated with sirolimus-eluting stents, 1400 treated with paclitaxel-eluting stents, and 2267 treated with bare-metal stents.

Heat and pH-Sensitive Nanoparticles Designed to Target Tumors  -  Feb 5, 2007
AZoNano.com,The hydrophobic core of this nanoparticle provides an accommodating environment for water-insoluble drugs such as doxorubicin and paclitaxel.

Heat and pH-sensitive nanoparticles designed to target tumors  -  Feb 5, 2007
Nanowerk LLC,Reporting its work in two papers – the first appears in the journal Biomaterials ("Targeted and intracellular delivery of paclitaxel using multi-functional

First International Trial of Drug-Eluting Peripheral Artery Stent ...  -  Jan 31, 2007
PipelineReview.com (press release),This is the first trial ever to investigate whether Paclitaxel-eluting stents can be used to successfully treat peripheral arterial disease (PAD),

Restenosis in Leg Arteries Prevented With Use of Drug-Eluting ...  -  Feb 1, 2007
DG NewsAnimal studies suggested that use of balloons coated with paclitaxel (Taxol) appeared to slow or halt the restenosis process. "Paclitaxel-coated balloons

Coated balloon keeps leg blood flowing  -  Jan 31, 2007
United Press InternationalAnimal studies suggested that use of balloons coated with paclitaxel -- also used to treat cancer under the trade name of Taxol -- might slow restenosis.

First International Trial of Drug-Eluting Peripheral Artery Stent ...  -  Jan 30, 2007
Genetic Engineering News (press release),Cook Medical's Zilver PTX Paclitaxel-Eluting Stent (DES) trial results demonstrated no stent fractures. The major adverse event (MAE) rate was equivalent to

Opto Circuits subsidiary Eurocor GmbH receives CE Mark approval ...  -  Feb 9, 2007
Equity Bulls,Opto Circuits India Ltd has announced that Eurocor GmbH the Company's wholly owned subsidiary has received the CE Mark Approval for its "DIOR" a Paclitaxel

Special Protocol Assessment Filed for Xyotax  -  Feb 1, 2007
Cancer Consultants (press release),Xyotax is a chemotherapy agent that links the active ingredient of Taxol® (paclitaxel) to a biodegradable polyglutatmate polymer. While paclitaxel and the

Taihua plans wins licence to sell anti-cancer in  -  Feb 5, 2007
Hemscott,The company said paclitaxel is used in drugs that fight ovarian, breast, lung and skin cancers, and is estimated to have generated sales of more than 9 bln

Lung cancer more likely in women: study  -  Jan 27, 2007
The Age,A clinical trial focusing on female lung cancer patients is now underway to see whether a newer form of the cancer drug paclitaxel is more effective than

Stents: Benefits vs. risks  -  Feb 23, 2007
Albany Democrat Herald,...stents most widely used in the United States — one by J & J and the other by Boston Scientific — are coated, respectively with sirolimus or paclitaxel.

Integrated BioPharma's Wholly-Owned Subsidiary, AgroLabs, Launches ...  -  Feb 8, 2007
PR Newswire (press release),Its pharmaceutical business operates a cGMP facility for the production and sale of Paclitaxel and related drugs and provides technical services through its

Paraplatin®/Cytoxan® a Possible Alternative for Ovarian Cancer  -  Feb 20, 2007
Cancer Consultants (press release),Carboplatin/cyclophosphamide or carboplatin/paclitaxel in elderly patients with advanced ovarian cancer? Analysis of two consecutive trials from the group

UK smallcap opening - Taihua edges up on move into South Korea market  -  Feb 5, 2007
Hemscott,This follows the award of a licence to sell its anti-cancer pharmaceutical ingredient paclitaxel in South Korea. The company plans immediate sales through

Angiotech reports fourth quarter results and updates 2007 ...  -  Feb 1, 2007
Earthtimes.orgA royalty revenue decline of approximately 22% in 2007 as compared to 2006, as a result of lower expected sales by BSC of paclitaxel-eluting stent systems.

Bern-Rotterdam analysis published: DES stent thrombosis risk ...  -  Feb 23, 2007
TheHeart.Org,...first with the sirolimus-eluting stent (SES; in 3823 patients), followed by the paclitaxel-eluting stent (PES; in 4323 patients). Over the study period,

EU panel backs Novartis' mock-up pandemic flu vaccine  -  Feb 23, 2007
MarketWatchAvastin (bevacizumab), from Roche Registration Ltd, to extend the indication to include Avastin in combination with paclitaxel for the first-line treatment

Pro-Pharmaceuticals Meeting Scheduled with the FDA  -  Feb 23, 2007
American Digital Networks (press release),...oxaliplatin, paclitaxel, cisplatin, and bevacizumab (Avastin(R)). Results show that DAVANAT(R) exhibits a broad spectrum of activity with tested drugs.

Valeant Pharmaceuticals Files Investigational New Drug Application ...  -  Feb 23, 2007
PharmaLive.com (press release),...patients receiving cisplatin alone, but this increases to a frequency of 90 percent to 100 percent when cisplatin is administered along with paclitaxel.

Data acquisition for the histoculture drug response assay in lung ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryYoshimasu T, Oura S, Hirai I, Kokawa Y, Okamura Y, Furukawa T. Dose response curve of paclitaxel measured by histoculture drug response assay [in Japanese].

Newly-Published Study Shows CAELYX(R) Plus Carboplatin to Be ...  -  Feb 16, 2007
netPR.pl (komunikaty prasowe),Standard therapy for recurrent ovarian cancer is a regimen containing paclitaxel and carboplatin. However neurotoxicity is a significant cumulative side

New understanding of how and why Taxol works in patients with ...  -  Feb 22, 2007
News-Medical.net,The taxanes are Taxol (also known as paclitaxel) and Taxotere (docetaxel). Taxol was originally derived from the Pacific yew tree, and Taxotere is a

Poniard Pharmaceuticals Announces Picoplatin Abstract Accepted for ...  -  Feb 22, 2007
PharmaLive.com (press release),In addition, results from an earlier Phase 1 study indicated that picoplatin can be combined safely with taxanes, such as docetaxel or paclitaxel,

Protein identified that regulates effectiveness of Taxol ...  -  Feb 22, 2007
PressZoom (press release),The taxanes are Taxol ( also known as paclitaxel ) and Taxotere ( docetaxel ). Taxol was originally derived from the Pacific yew tree, and Taxotere is a

Chemotherapy resistance and oncogene expression in non–small cell ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgeryMETHODS: Chemotherapy resistance to doublets—carboplatin and paclitaxel, cisplatin and navelbline, cisplatin and docetaxel, and cisplatin and

Drug-Eluting Stents Best After Artery Re-Closure  -  Jan 29, 2007
Forbes,In another study in the same journal issue, Italian researchers looked at drug-eluting stents to see which medication, sirolimus or paclitaxel, worked best.

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