Recent news on Phenytoin

Epilepsy a Disease Like Any Other  -  25 May 2007
AllAfrica.com,Antiepileptic drugs like phenytoin, carbamazepine, sodium valproate, gabba pentin etc have to be taken for long, mostly for life in maintenance doses.

Mum's epilepsy med linked to low IQ in kids  -  May 11, 2007
National Review of Medicine,In an ongoing study, now in its seventh year, of the effects of four common antiepileptic drugs (AEDs) — carbamazepine, lamotrigine, phenytoin and valproate

Epilepsy Drug Valproate Used During Pregnancy Linked To Lower IQ ...  -  May 8, 2007
Science Daily (press release)The study looked at IQ test results for 187 two-year-old children of mothers who took the epilepsy drugs carbamazepine, lamotrigine, phenytoin, or valproate

Popular epilepsy drug damages the unborn  -  May 7, 2007
News-Medical.net,Children whose mothers took carbamazepine scored an average of 93 points on the IQ tests, those on phenytoin 93, lamotrigine 96, and 84 for valproate.

IQ results for children of mothers who took the epilepsy drugs ...  -  May 6, 2007
News-Medical.net,On an IQ test, children whose mothers took carbamazepine scored an average of 93 points, compared to 93 for those who took phenytoin, 96 for lamotrigine,

Study finds more risks to unborn in epilepsy drug Depakote  -  May 4, 2007
Los Angeles Times,Twenty-four percent of children whose mothers took valproate had IQs below 70, compared to 13% for carbamazepine, 11% for lamotrigine and 12% for phenytoin.

Women Taking Antiepileptics Give Birth to Babies at Risk ...  -  May 4, 2007
DG NewsResults demonstrated that high rates of low birth weight (LBW) were found in newborns that were exposed to valproate, carbamazepine, phenytoin or

Epilepsy drug linked to increase in retarded children  -  May 4, 2007
Kentucky.com,In addition to valproate, the drugs were carbamazepine, sold as Tegretol, lamotrigine (Lamictal) and phenytoin (Dilantin).

Lower IQ for Children of Women who Took Epilepsy Drug  -  May 6, 2007
drkoop.comFor those who took carbamazepine or phenytoin, it was 12 percent, and 9 percent for children whose moms took lamotrigine. Results also show lower IQ scores

Anti-Epileptic Drug Intake May Result In Children With Mental ...  -  May 5, 2007
MedIndia,...at IQ results of 187 children born to mothers who had taken the epilepsy drugs carbamazepine, lamotrigine, phenytoin, or valproate during pregnancy.

General Practitioners and Women Still Not Getting Valproate Message  -  May 11, 2007
Medscape (subscription)Carbamazepine, lamotrigine, and phenytoin did not affect this relationship. But valproate did interfere with this normal relationship," said Dr. Meador.

Zonisamide Syrup (Zonisamide capsule) Information  -  May 20, 2007
American Chronicle,Drugs that induce liver enzymes (eg, carbamazepine, phenobarbital, phenytoin): May increase the metabolism and Cl and decrease the t ½ of zonisamide.

Epilepsy Drug Linked to Low IQ  -  May 3, 2007
WebMDThe three other drugs studied are also widely used: Lamictal; carbamazepine, for which a common brand name is Tegretol; and phenytoin, often sold as

AAN: In Utero Exposure to Valproate Lowers IQ  -  May 3, 2007
MedPage Today,...they found that for women taking either carbemazepine, lamotrigine, and phenytoin, there was a positive association between the mother's IQ and that of

New Data Shows Once a Day Lamictal XR is Effective in Treating ...  -  May 2, 2007
PharmaLive.com (press release),...for conversion to monotherapy in adults with partial seizures taking carbamazepine, phenytoin, phenobarbital, primidone, or valproate as the single AED.

Sun Pharma sales growth 30%, Profit increased 35%  -  May 19, 2007
Moneycontrol.com,Notable approvals during the year include final approval for generic phenytoin, nimodipine and gabepentin which have since been launched and a tentative

Halozyme Therapeutics Reports 2007 First Quarter Financial Results  -  May 10, 2007
Earthtimes.orgFurosemide, the benzodiazepines, and phenytoin are incompatible with hyaluronidase. Please see accompanying package insert for full Prescribing Information.

Epilepsy Drug Damages Unborn Babies  -  May 7, 2007
E Canada Now,This was compared to far lower levels in other epilepsy drugs such as carbamazepine which was at 12%, lamotrigine at 9%, and phenytoin at 12%.

Epilepsy Drug Lowers Children's IQ  -  May 4, 2007
Dog Flu Diet and Diseases,...scored 12 points lower on intelligence quotients when their mothers took the drug, compared to 3 other drugs; Lamictal, carbamazepine, or phenytoin.

Study: Valproate linked to kids' low IQ  -  May 3, 2007
United Press InternationalWhen compared to treatment with other drugs like carbamazepine, lamotrigine and phenytoin, the intelligence quotient of 2-year-old children was 9 to 12

Find cause of mystery  -  May 1, 2007
Times Daily (subscription),...triptans, painkillers (including oxycodone, morphine, tramadol), common anti-seizure meds (such as carbamazepine, gabapentin, phenytoin) or surgery,

Baxter Introduces HYLENEX for Use in Ophthalmic Surgery  -  Apr 27, 2007
PR Newswire (press release),Furosemide, the benzodiazepines, and phenytoin are incompatible with hyaluronidase. The full prescribing information for HYLENEX should be consulted prior

Abraxis BioScience Receives FDA Tentative Approval for ...  -  Apr 20, 2007
Compliance Home,Fosphenytoin Sodium Injection is indicated for short-term parenteral administration when other means of phenytoin administration are unavailable,

No urgency in drug delivery: doctor  -  Apr 12, 2007
Border Mail,She said when consultant neurosurgeon Nicholas Little told her on November 7 to prescribe Vanessa the anti-convulsant drug phenytoin, also known as Dilantin

Golf ball victim 'not that urgent'  -  Apr 11, 2007
The Age,Dr Williams told the court that on November 7, consultant neurosurgeon Nicholas Little had told her to give the patient the anti-convulsant drug Phenytoin.

Treating Vanessa 'wasn't that urgent'  -  Apr 11, 2007
Sydney Morning Herald,After Vanessa's family raised concerns that she could be allergic to Phenytoin, Dr Williams asked a more senior doctor, neurosurgical registrar Azizi Bakar,

Psychosis Following Initiation of Zonisamide  -  Apr 2, 2007
Am J Psychiatry (subscription)Phenytoin, primidone, and vagal nerve stimulator placement 30 months before her admission led to improved seizure control, with no apparent psychiatric

Positive Results Prompt US National Cancer Institute to Make ...  -  Apr 12, 2007
PR Newswire (press release),Examples of commonly used drugs that may significantly interact with Gleevec include acetaminophen, warfarin, erythromycin, and phenytoin.

Cures can be killers  -  Apr 18, 2007
Alberta Daily Herald Tribune (subscription),The anti-seizure drug phenytoin also can interact adversely with cancer-related drugs, ''but there were other less common interactions that we came across

Cancer patients at risk for dangerous drug interactions: study  -  Apr 17, 2007
Brandon Sun,The anti-seizure drug phenytoin also can interact adversely with cancer-related drugs, "but there were other less common interactions that we came across,"

Obsessive-Compulsive Disorder With Hydrocephalus: Effect of ...  -  Feb 16, 2007
Journal of Neuropsychiatry (subscription)Five months after he stopped taking phenytoin, he had another attack of generalized tonic-clonic seizures and severe headaches; hence, the phenytoin regimen

TRx Pharma introduces FOLMOR for treatment of cardiovascular disease  -  Feb 7, 2007
Carolina Newswire (press release),Concurrent use of phenytoin and folic acid may decrease the effectiveness of phenytoin, but no such decrease has been reported with the use of FOLMOR.

Halozyme and Baxter Expand Global HYLENEX Collaboration  -  Feb 19, 2007
Drug Newswire (press release),Furosemide, the benzodiazepines, and phenytoin are incompatible with hyaluronidase. Please see accompanying package insert for full Prescribing Information.

KU Professor, Student Find New Variable in Common Drug Therapy Problem  -  Feb 14, 2007
Kansas City infoZine,...lithium carbonate, phenytoin, theophylline and warfarin) for which small changes in dosage level could result in no beneficial effect or be toxic,

African-American Women Who Have Received HIV Treatment Are Sought ...  -  Feb 7, 2007
Medical News Today (press release),Coadministration is not recommended with carbamazepine, phenobarbital, phenytoin, rifampin, lopinavir/ritonavir, saquinavir, lovastatin, pravastatin,

(BPRW) AFRICAN-AMERICAN WOMEN WHO HAVE RECEIVED HIV TREATMENT ARE ...  -  Feb 6, 2007
Black PR Wire (press release),...life-threatening events.1 Coadministration is not recommended with carbamazepine, phenobarbital, phenytoin, rifampin, lopinavir/ritonavir, saquinavir,

Analysis: Newer/older epilepsy drugs equal  -  Feb 5, 2007
Science Daily (press release)...than anti-epileptic drugs, no comparative study has demonstrated improved efficacy for any of these over carbamazepine, phenytoin, or valproic acid."

Sun Pharma Reports Strong Performance  -  Jan 29, 2007
PharmaLive.com (press release),Notable approvals during the quarter include final approval for Phenytoin which has since been launched and a tentative approval for Amifostine for

Uncovering A New Reason Why Patients Respond Differently To The ...  -  18 Jan 2007
Medical News Today (press release),...phenytoin, theophylline and warfarin) for which very small changes in dosage level could cause either subtherapeutic or toxic results, they note.

Sun Pharma redeems 6% cumulative redeemable preference shares  -  Dec 21, 2006
Myiris.com,USFDA approval to market extended phenytoin sodium capsules, USP 100mg (Phenytoin ER) will help Sun Pharma introduce its bio-equivalent soon.

Danger drugs stolen  -  Dec 29, 2006
Cambridge Evening News,The haul included 120 tablets of pethodin, 56 tablets of phenytoin sodium, 200 tablets of codine phosphate and 112 tablets of diazepam.

Uncovering A New Reason Why Patients Respond Differently To The ...  -  Jan 16, 2007
Science Daily (press release)...phenytoin, theophylline and warfarin) for which very small changes in dosage level could cause either subtherapeutic or toxic results, they note.

Gastrointestinal Medications  -  Jan 5, 2007
Psychosomatics (subscription)In other studies, cilostazol, 20 proguanil, 21 diazepam, and phenytoin 22 levels increased in the presence of omeprazole due to inhibition of CYP 2C19.

Dr. Paul Donohue  -  Jan 16, 2007
Sarasota Herald-Tribune,If his current medicines are not working, there are others, like carbamazepine (Tegretol), phenytoin (Dilantin) and amitriptyline, alone or in combinations.

For Utley, life's meant to be lived  -  Jan 13, 2007
New Haven Register (subscription),...prior to Saturday morning, is working on the recovery of locomotive function for those afflicted with spinal cord injury, using a drug called phenytoin.

Pivotal Submission Data Shows Tasigna(R) Achieved Impressive ...  -  Dec 26, 2006
Medical News Today (press release),Examples of commonly used drugs that may significantly interact with Gleevec include acetaminophen, warfarin, erythromycin, and phenytoin.

Erythema multiforme  -  Jan 10, 2007
RDH,The use of medications is also associated with erythema multiforme, including sulfonamides, penicillin, barbiturates, phenylbutazone, and phenytoin.

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BUY ALTACE, Altace Online, Altace Cheap  -  Dec 25, 2006
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Buy Ambien  -  Dec 22, 2006
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Neuro-Ophthalmology for Neuroradiologists  -  Jan 9, 2007
AJNR (subscription),...spinocerebellar degenerations, and toxic metabolic conditions such as medication toxicity (specifically phenytoin, carbamazepine, and lithium).

Pivotal Submission Data Shows Tasigna(R) Achieved Impressive ...  -  26 Dec 2006
Medical News Today (press release),Examples of commonly used drugs that may significantly interact with Gleevec include acetaminophen, warfarin, erythromycin, and phenytoin.

New Study Demonstrates Efficacy Of Pfizer's Aromasin For Early ...  -  26 Dec 2006
Medical News Today (press release),Dose modification is recommended for patients who are receiving certain medications, including strong CYP 3A4 inducers such as rifampicin and phenytoin.

Sección internacional  -  26 Dec 2006
Bolsamania.com,...(PRN) - Caraco Pharmaceutical Laboratories Ltd. to Market Extended Phenytoin Sodium Capsules, USP 100mg ... [+]. (PRN) - Remarks by President Bush at

International Approvals: Byetta and Noxafil  -  26 Dec 2006
Medscape (subscription)Because cimetidine, rifabutin, and phenytoin can decrease posaconazole plasma concentrations, their coadministration should generally be avoided unless the

Caraco Pharmaceutical Laboratories Ltd. to Market Extended ...  -  Dec 17, 2006
Drug Newswire (press release),Sun Pharma recently received approval from the US Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Phenytoin ER.

Caraco Pharmaceutical (CPD) to Market Extended Phenytoin Sodium ...  -  Dec 15, 2006
StreetInsider.com (subscription),Phenytoin ER is an anticonvulsant drug. It is useful in the treatment of seizures related to epilepsy and neurosurgery.

Caraco Pharmaceutical Laboratories Ltd. to Market Extended ...  -  Dec 15, 2006
Earthtimes.org15 -- Caraco Pharmaceutical Laboratories, Ltd. announced today that it will market Extended Phenytoin Sodium Capsules, USP 100mg (Phenytoin ER) on behalf of

Caraco to Distribute Generic Phenytoin  -  Dec 15, 2006
Houston Chronicle,DETROIT — Caraco Pharmaceutical Laboratories Inc. said late Friday it will market extended phenytoin sodium capsules for Sun Pharmaceutical Industries Ltd.

Sun, Lupin to add two drugs in US market  -  Dec 19, 2006
Business Standard,While the final USFDA approval to market Extended Phenytoin Sodium Capsules, USP 100mg (Phenytoin ER) will help Sun Pharma introduce its bio-equivalent soon

Market Report -- In Play (CPD)  -  Dec 15, 2006
MSN MoneyCaraco Pharma says to market extended Phenytoin sodium capsules, USP 100mg Co announces that it will market Extended Phenytoin Sodium Capsules,

#1 - ZOLPIDEM SIDE EFFECTS , ambien zolpidem  -  Dec 25, 2006
Indymedia Colombia,...and decrease your body's absorption of xenical body mass index (BMI) greater than 120 mg of paxil elevated phenytoin level after weeks of paxil enzymes.

BUY ALTACE, Altace Online, Altace Cheap  -  Dec 25, 2006
Indymedia Colombia,Best phenytoin of amantadine, alprazolam related to analgesic both pantoprazole. Er, one goodhearted norvasc and cox2 drug expectantly waked underneath some

Buy Ambien  -  Dec 22, 2006
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Arteriovenous Malformation - Cerebral  -  Dec 14, 2006
WNBC,...for small deep AVMS which are difficult to remove by surgery. Anti-convulsant medications, such as phenytoin, are usually prescribed if seizures occur.

Study of Dasatinib or 800 Mg of Imatinib Mesylate Shows Patients ...  -  Dec 14, 2006
DG NewsDrugs that may decrease dasatinib concentrations are: CYP3A4 inducers (eg, dexamethasone, phenytoin, carbamazepine, rifampicin, phenobarbital).

For those with epilepsy, knowledge is best ally  -  Dec 9, 2006
North County Times,In the early 20th century, phenobarbital and phenytoin (trademarked Dilantin) followed. A long string of other drugs followed. Patients respond differently

No Weight Gain Seen in Patients on Investigative Antiepileptic ...  -  Dec 6, 2006
DG NewsPhenytoin, lamotrigine and leviteracetam are weight neutral. While the cohort of patients overall did not show any weight gain, 3 patients did gain weight,

From Bedside to Bench: How the Epidemiology of Clinical Practice ...  -  Dec 7, 2006
Psychiatric Services (subscription)Benzodiazepines (such as lorazepam), anticonvulsants (such as phenytoin), beta-adrenergic blockers (such as propranolol), corticosteroids (such as

PAINFUL FACIAL TIC MAKES LIFE UNBEARABLE  -  Dec 2, 2006
Charlotte Sun-Herald,Carbamazepine, phenytoin and lamotrigine are the names of some of the medicines that are often prescribed and often bring relief. However, if medicines fail

Interictal Psychosis After Stroke With Forced Normalization  -  Nov 29, 2006
Journal of Neuropsychiatry (subscription)...times a week after the long and adequate treatment with antiepileptic drugs (carbamazepine, 1100 mg/day; phenytoin, 325 mg/day; clobazam, 20 mg/day).

Patient Management Exercise FOR PSYCHOPHARMACOLOGY  -  Dec 6, 2006
Focus (subscription)It can cause hepatotoxicity, increases drug levels of phenytoin, isoniazid, and anticoagulants. It can cause hepatitis. D5 +2 A Thiamine is a cofactor for

Denenberg: Advocates Now Stress Caution When Using Generic Drugs  09 Nov 2006
The next day I learned that she had been given generic phenytoin instead of Dilantin for the last few days. I am convinced that is why she suffered seizures.". ... -Evening Bulletin, PEOPLE’S PHARMACY: How good are generic drugs?  09 Nov 2006
Patients whose epilepsy was well controlled on the anticonvulsant Dilantin reported seizures when switched to generic phenytoin. ... -Tuscaloosa News (subscription), Halozyme Therapeutics Reports Third Quarter 2006 Financial Results  09 Nov 2006
Precautions for the use of Hylenex consist of incompatibility with furosemide, benzodiazepines and phenytoin, and recommendation for consulting appropriate ... -Yahoo! News (press release) An Interaction Between Aspirin and Valproate: The Relevance of ...  Oct 30, 2006
Another example of this kind of drug-drug interaction would be the impact of valproate on the free phenytoin concentration (Table 1). As with the valproate ... -Am J Psychiatry (subscription) Gleevec(R) Approved in the US for Five Rare Life-Threatening ...  Oct 25, 2006
...least 50% and clinical response should be carefully monitored in patients receiving Gleevec tablets with a potent CYP3A4 inducer such as rifampin or phenytoin. ... -Drug Newswire (press release), Addressing Psychiatric Comorbidities in Patients With Epilepsy  Oct 26, 2006
In addition, antipsychotic agents can have additive toxic effects in combination with antiepileptic agents, such as phenytoin (Dilantin, Phenytek). ... -Psychiatric Times, Taro Pharma Reveals Receipt Of FDA Approval For Extended Phenytoin ...  Sep 6, 2006
...that it received approval from the US Food and Drug Administration for its Abbreviated New Drug Application or ANDA for Extended Phenytoin Sodium Capsules, USP ... -Trading Markets

Taro Receives ANDA Approval For Extended Phenytoin Sodium Capsule ...  Sep 6, 2006
...has received approval from the US Food and Drug Administration ("FDA") for its Abbreviated New Drug Application ("ANDA") for Extended Phenytoin Sodium Capsules ... -PharmaLive.com

Taro:FDA OKs ANDA for Extended Phenytoin Sodium Capsules  Sep 6, 2006
...(TARO) received approval from the Food and Drug Administration for its abbreviated new drug application for extended phenytoin sodium capsules for treating ... -Therapeutics Daily (subscription)

Taro receives FDA approval for epilepsy drug  Sep 6, 2006
Industries (Nasdaq: TARO) reported today that it has received approval from the US Food and Drug Administration (FDA) for its Extended Phenytoin Sodium capsules ... -Globes

Taro gets FDA approval for epilepsy drug  Sep 6, 2006
Israeli drug maker says agency approved 100 milligram capsules of phenytoin sodium, active ingredient of Pfizer Inc.'s Dilantin Kapseals. ... -Ynetnews

Taro Gets FDA Approval for Epilepsy Drug  Sep 6, 2006
The company said the agency approved 100 milligram capsules of phenytoin sodium, the active ingredient of Pfizer Inc.'s Dilantin Kapseals. ... -Houston Chronicle

Taro Pharmaceutical says generic seizures drug gets nod  Sep 6, 2006
...(TARO.O: Quote, Profile, Research) on Wednesday said US regulators had approved its generic extended phenytoin sodium capsules to treat seizures related to ... -Reuters

Epilepsy Common in Patients With Low-Grade Glioma: Presented at ...  Sep 5, 2006
The first-line agents were carbamazepine, phenytoin and sodium valproate; 40% of patients also received the newer antiepileptic drugs (AEDs), 31% of which ... -DG News

IBM buys full ownership of Brazilian company  Sep 7, 2006
...surgery. The product, known as extended-release phenytoin capsules, is a generic version of Dilantin, a medication produced by Pfizer. -The Journal News.com

Neuroacanthocytosis: Presenting With Depression  Sep 8, 2006
He also had three episodes of generalized tonic clonic seizures when he was 26 years old; since then, he has been stabilized on 300 mg of phenytoin. ... -Journal of Neuropsychiatry (subscription)

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