Recent news on Propofol

Propofol Plus Fentanyl Makes a Better Sedative for Children ...  -  May 9, 2007
DG NewsThe study found the combination of propofol and fentanyl resulted in fewer cases of hypotension and airway obstruction and a reduction in the severity of

The Utility of Supplemental Oxygen during Emergency Department ...  -  Apr 27, 2007
AEM (subscription)To determine whether supplemental ; oxygen (SO) reduces the rate of hypoxia in patients receiving propofol for emergency department (ED) procedural sedation

Aquavan(R) (Fospropofol Disodium) Injection Data Presented at ...  -  May 24, 2007
PipelineReview.com (press release),Aquavan Injection is a proprietary water-soluble prodrug of propofol that is in clinical development for moderate sedation of patients undergoing

XenoPort Reports First Quarter Financial Results  -  May 8, 2007
Genetic Engineering News (press release),XenoPort plans to commence pre-clinical development activities to support the filing of an IND in 2008 for XP20925, a transported prodrug of propofol.

Pennsylvania Patient Safety Authority Issues Annual Report for 2006  -  May 1, 2007
PR Newswire (press release),...the March 2006 issue, one article raised concerns regarding the administration and monitoring of a popular sedation drug call Propofol (PRO- pa-fall).

Positive 'Restless Legs' Data Send XenoPort Shares Soaring  -  Apr 25, 2007
BioWorld Online,The company also has in its pipeline XP21279, a prodrug of levodopa, for Parkinson's disease and XP20925, a prodrug of the aesthetic propofol.

Positive 'Restless Legs' Data Send XenoPort Shares Soaring  -  26 Apr 2007
BioWorld Online,The company also has in its pipeline XP21279, a prodrug of levodopa, for Parkinson's disease and XP20925, a prodrug of the aesthetic propofol.

You won't feel a thing  -  Apr 4, 2007
Economist,They tested propofol, a member of a class of common modern drugs and compared it with ketamine, an older sedative now generally restricted to use in minor

Manhattan Pharmaceuticals Completes $8.6 Million Private Placement  -  Apr 5, 2007
Drug Newswire (press release),...for the treatment of psoriasis, and Propofol Lingual Spray, a convenient, proprietary lingual spray formulation of propofol, the world's best-selling

Dentist 'forgot' to seek patient consent  -  Apr 19, 2007
News Shopper,Mrs A had received 4mg of Midazolam, 50mcg of Fentanyl, 10mg of Ketamine and 5mg of Propofol, but was not told why she was given the four drugs when one

Death From Cosmetic Surgery Is Never Acceptable  -  Apr 18, 2007
openPR (press release),The same experience can be had with intravenous propofol at BIS between 60-75, a level Dr. Friedberg has trademarked as an integral part of MIA.TM

Tot captures the hearts of emergency crews  -  27 Mar 2007
Buffalo News,...to deliver as much air as possible while Anna is rushed to Women and Children’s Hospital for a shot of propofol, an anesthetic that breaks the seizure.

Manhattan Pharmaceuticals Completes Enrollment in Phase 2a Study ...  -  Feb 26, 2007
Drug Newswire (press release),...for the treatment of psoriasis, and Propofol Lingual Spray, a convenient, proprietary lingual spray formulation of propofol, the world's best-selling

MGI PHARMA Announces Positive Results from a Pivotal Phase 3 Study ...  -  Mar 21, 2007
PipelineReview.com (press release),Aquavan(R) (fospropofol disodium) Injection, a proprietary water-soluble prodrug of propofol that after intravenous injection is rapidly converted by an

Adult Drugs for Sick Kids  -  Mar 5, 2007
MSNBCWhile some drugs, like acetaminophen, were found to be rarely used off label, powerful sedatives like Propofol, Midazolam and Fentanyl, says Shah,

Dangerous drugs stolen from vet's surgery  -  Mar 2, 2007
Wigan Observer,Torbugesic 3 x bottles; Domitor 2 x bottles; Antisedan 2 x bottles; Narkaten (Ketamine) 2 x bottles; Propofol 16 x bottles; Isoflo 3 x bottles;

Study on waking and dreaming during surgery  -  Feb 25, 2007
News-Medical.net,The dreamers where also more likely to be treated with the anaesthetic propofol or receive regional anaesthesia, and were more likely to open their eyes

Manhattan Pharmaceuticals, Inc. Completes Enrollment In Phase 2a ...  -  Feb 22, 2007
PipelineReview.com (press release),...for the treatment of psoriasis, and Propofol Lingual Spray, a convenient, proprietary lingual spray formulation of propofol, the world's best-selling

Dreaming while under anesthesia no cause for alarm  -  Feb 20, 2007
ReutersDreamers where also more likely to be treated with the anesthetic propofol or receive regional anesthesia and were more likely to open their eyes sooner

Anaesthetics linked to Alzheimer's  -  Feb 7, 2007
TVNZ,The effect was seen with propofol after exposure for 48 hours, but no clumping was seen with thiopental, the researchers report.

Role Of Anesthetics In Alzheimer's Disease  -  Jan 28, 2007
Medical News Today (press release),Previous studies by the Pittsburgh researchers found that the inhaled anesthetics halothane and isoflurane and the intravenous anesthetic propofol

IRadimed Corporation Awarded Novation Contract for its award ...  -  Feb 22, 2007
Drug Newswire (press release),...providing the ability to adjust critical medications, such as Propofol, which is used for Anesthesia without having to stop the scan.

Dreaming under anaesthesia okay  -  Feb 20, 2007
TVNZ,Dreamers were also more likely to be treated with the anaesthetic propofol or receive regional anaesthesia and were more likely to open their eyes sooner

Anaesthetics may Cause Brain Disorder in Elderly  -  Jan 29, 2007
MedIndia,US, found that halothane and isoflurane - two anaesthetics that are inhaled - and the injected drug propofol cause symptoms of brain disorder.

Manhattan Receives Notification from AMEX of Non-Compliance of ...  -  Jan 12, 2007
Primenewswire (press release),...for the treatment of psoriasis, and Propofol Lingual Spray, a convenient, proprietary lingual spray formulation of propofol, the world's best-selling

CONSCIOUS SEDATION  -  Dec 1, 2006
EndoNurse,Propofol or older drugs? Administration by an anesthesiologist or a nurse anesthetist, or even a staff nurse? End-tidal CO2 monitoring or just pulse

Manhattan Pharmaceuticals to Webcast Annual Shareholder Meeting  -  Dec 14, 2006
Primenewswire (press release),...for psoriasis, and Propofol Lingual Spray, a convenient, proprietary lingual spray formulation of propofol, the world's best-selling general anesthetic,

Plavix (Clopidogrel) and Aspirin  -  Dec 8, 2006
Angioplasty.Org,Especially since our youngest son died last year from the propofol infusion syndrome. The Christian Scientists have a point.

Manhattan Pharmaceuticals Expands Phase 2a Obesity Clinical Trial ...  09 Nov 2006
...is also developing PTH (1-34), a peptide believed to be a regulator of epidermal cell growth, for the treatment of psoriasis, and Propofol Lingual Spray, a ... -Medical News Today (press release), Propofol and Upper Airway Size  Nov 1, 2006
Effect of propofol anesthesia and continuous positive airway pressure on upper airway size and configuration in infants. Anesthesiology. ... -AAP Grand Rounds (subscription), ASCS UNDER SCRUTINY  Nov 7, 2006
...the AAAHC’s perspective, an important issue for some organizations is determining who is qualified to administer certain drugs such as propofol to induce ... -Today's SurgiCenter, Rodman & Renshaw Healthcare Conference 2006 Presenter Profiles  Nov 3, 2006
Manhattan Pharmaceuticals is also developing PTH (1-34), a peptide believed to be a regulator of epidermal cell growth, for psoriasis and Propofol Lingual Spray ... -Business Wire (press release), Anesthetics may Increase Risk of Alzheimer's Disease  Oct 26, 2006
Three anesthetics -- halothane, isoflurane, and propofol -- were found to encourage clumping of the protein, all at higher concentrations than are normally ... -Ivanhoe, Boffo Baxter not hot enough  Oct 20, 2006
...million. The company blamed generic drug competition. Sales of its anesthetic Propofol dived 60 percent from a year ago. "While ... -Chicago Sun-Times, Ease in Sando drugs shortage  Oct 19, 2006
...association, said elective surgeries resumed at the San Fernando General Hospital yesterday after surgeons were provided with a supply of Propofol, which is ... -Trinidad & Tobago Express, Details of Hospital's Failure  Oct 21, 2006
..."At the time of the survey it was not clear what the facility's guidelines for the use of propofol were," inspectors wrote of a common anesthetic. ... -Los Angeles Times, ALZHEIMER'S RISK IN OPS  Oct 26, 2006
Lab and animal tests showed drugs like isoflurane and propofol - used in Europe and the US - may encourage the formation of protein clumps in the brain that ... -Mirror.co.uk, Hospitals Honored by DVHC for Innovations in Medication Safety  Oct 26, 2006
Both hospitals developed evidence-based protocols to improve medication safety precautions for administration of Propofol, a short-acting general anesthetic ... -Genetic Engineering News (press release), Alzheimer's alarm over anesthetics  Oct 25, 2006
...inhaled anaesthetics halothane and isoflurane encourage clumping of beta amyloid protein, as does the commonly used intravenous anaesthetic propofol, at least ... -EurekAlert (press release), View Nanobiotechnology’s Contributions to the Pharmaceutical ...  Oct 16, 2006
...forecasts indicate that products that will reach the market in 2006 will include the first nanoparticulate drugs from SkyePharma (propofol), Nanobio (NanoHpx ... -Nanotechwire.com, Dead man's estate sues sheriff, city  Oct 19, 2006
The lawsuit also states that a toxicology test showed the sedative drug propofol in Harvey's system at the time of death, but that no other drugs were present. ... -Roanoke Times, ‘The Children's Hospital’  Oct 13, 2006
She shouted curses at her child while the anesthesiologist, scowling, pushed white, milky propofol into her veins, trying to shut her up. ... -New York Times, Blue Cross bows to doctors  Sep 21, 2006
Blue Cross said it still agrees with the nation's three leading gastroenterology societies, which have said propofol, the more-expensive anesthesia, is neither ... -St. Louis Post-Dispatch

Manhattan Pharmaceuticals' Alan G. Harris, MD, PhD to Chair Metab ...  Sep 19, 2006
Pharmaceuticals is also developing PTH (1-34), a peptide believed to be a regulator of epidermal cell growth, for psoriasis, and Propofol Lingual Spray, a ... -PharmaLive.com

Safety Test Results On Children's Drugs Not Always Reaching ...  Sep 15, 2006
In another study, the drug Propofol, while effective when used to induce or maintain anesthesia in critically ill patients, proved to have an increased ... -Medical News Today

US court rules against Mayne on propofol  -  Nov 16, 2006
The Age,A United States appeals court has upheld a ruling that drugs manufacturer Mayne Pharma Ltd's injectable formulation of propofol has infringed a patent held

Claris to become one of top three Propofol manufacturers globally ...  -  Nov 20, 2006
TechWhack,Profol is the advanced IV anesthetic propofol - the Anesthetic of choice globally due to its key benefits of faster and clear headed recovery viz-a-viz

Mayne Loses Appeal Over Generic Propofol  -  Nov 17, 2006
Los Angeles Times,..."Mayne Pharma is therefore prohibited from marketing its Propofol product until expiry of the patents in question," Mayne said in a statement.

Mayne Loses Appeal Over Generic Propofol  -  Nov 17, 2006
Forbes,Australian pharmaceutical group Mayne Pharma Ltd. said Friday it has lost a US court appeal over its generic formulation of the anesthetic product Propofol.

Mayne loses appeal over generic Propofol  -  Nov 17, 2006
Meadow Free Press,...pharmaceutical group Mayne Pharma Ltd. said Friday it has lost a US court appeal over its generic formulation of the anesthetic product Propofol.

CONSCIOUS SEDATION  -  Dec 1, 2006
EndoNurse,Propofol or older drugs? Administration by an anesthesiologist or a nurse anesthetist, or even a staff nurse? End-tidal CO2 monitoring or just pulse

Australia's Mayne Pharma injectable anaesthesia drug blocked by US ...  -  Nov 16, 2006
Forbes,SYDNEY (XFN-ASIA) - Mayne Pharma Ltd said its injectable form of the anaesthesia drug Propofol has been blocked by a US federal court.

VITAL SIGNS - The pharmaceuticals and biotechnology synopsis  -  Nov 17, 2006
egoli.com.au,Propofol is used to induce and maintain general anaesthesia and sedation in patients. The decision follows an earlier 2005 finding by the US District Court

Corporate Briefs  -  Nov 25, 2006
Calcutta Telegraph,Claris has doubled its capacity and plans to capitalise on its manufacturing capability of emulsions and lipids that includes propofol.

Stocks to watch  -  Nov 20, 2006
Sydney Morning Herald,Last week a United States appeals court upheld a ruling that Mayne Pharma's injectable formulation of propofol had infringed a patent held by another

Mayne Pharma Loses US Anesthetic Patent Infringement Suit  -  Nov 16, 2006
BloombergThe decision follows a US district court finding that Mayne Pharma's injectable drug propofol infringed patents held by AstraZeneca Plc, the Melbourne-based

Studies Probe Anesthesia, Sleep Links  -  Nov 21, 2006
Journal of American Medical Association (subscription),Half the rats were then anesthetized for 6 hours with a continuous infusion of propofol, a common anesthetic, in a fat emulsion; the other half were infused

Plavix (Clopidogrel) and Aspirin  -  Dec 8, 2006
Angioplasty.Org,Especially since our youngest son died last year from the propofol infusion syndrome. The Christian Scientists have a point.

EDITORIAL: Other Views: It Isn't Easy to Cut Wasteful Medical ...  Aug 21, 2006
...squeamish. It involves a drug called propofol, which provides deep sedation of the kind most associate with a general anesthetic. ... -International News Service

Doctors, insurers differ over drug  Aug 11, 2006
Debates over the drug, propofol, are occurring in health care markets across the country as insurers limit its use and doctors remain divided. ... -St. Louis Post-Dispatch

Hospira Reports Second-Quarter 2006 Results  Aug 9, 2006
...<PRE> Significant Events for the Second Quarter -- Launched several new injectable generic products, including propofol, sodium bicarbonate in Hospira's ... -Black Enterprise

Geisinger opens area's second endoscopy center  Aug 4, 2006
...for patients. The setup allows the use of Propofol, a sedative that allows for better pain management, Lichtenstein said. He said ... -Centre Daily Times

Maelor plc Announces New Board Appointment  Aug 7, 2006
Maelor has various products under development including micelle propofol, a reformulation of the world's biggest selling general anaesthetic. -Biotechnology Investment Today

Hospira Reports Second-Quarter 2006 Results  Aug 9, 2006
Significant Events for the Second Quarter -- Launched several new injectable generic products, including propofol, sodium bicarbonate in Hospira's proprietary ... -PR Newswire

Cardioversion sedation with propofol a better choice for elders ...  Jul 3, 2006
2006 JUL 3 - (NewsRx.com) -- Sedation during cardioversion with propofol may be a better choice than midazolam for older patients. ... -Therapeutics Daily (subscription)

Manhattan Pharmaceuticals to Present at 2nd Annual Obesity Drug ...  Jul 19, 2006
Pharmaceuticals is also developing PTH (1-34), a peptide believed to be a regulator of epidermal cell growth, for psoriasis, and Propofol Lingual Spray, a ... -PrimeZone

Hospital worker keeps job despite drugs admission  Jun 30, 2006
...from Bath, was working as an operating department practitioner at the hospital in April 2005 when he took the anaesthetic drugs Propofol and Midazolam and a ... -This is Wiltshire.co.uk

TechMARK movers: SkyePharma skips back  Jun 28, 2006
In April the company announcd that it had agreed with its US partner Endo Pharmaceuticals to terminate the development of its injectable anaesthetic Propofol. -MoneyWeek (Subscription)

Will extreme measures work where normal ones haven't?  Jul 11, 2006
He's handsome, and I suddenly feel self-conscious about my greasy hair. The needle goes into the IV tube, injecting propofol, an anesthetic. ... -OCRegister

Trip to dentist that proved fatal  Jul 3, 2006
Dr Viljoen's criticisms included that Dr Pegios used a "very unusual" IV drug regimen with "a very dangerous combination of midazolam and propofol which is not ... -Sydney Morning Herald

Abraxis BioScience Completes Acquisition of the AstraZeneca US ...  Jun 28, 2006
Products in this acquisition encompass over 100 dosage forms and include the leading branded anesthetic agent, Diprivan(R) (propofol), and Naropin(R ... -Genetic Engineering News

SkyePharma PLC - Annual General Meeting Statement  Jun 28, 2006
...the USA. Finally we have agreed with our US partner Endo Pharmaceuticals to terminate development of Propofol IDD-D(TM). We believe ... -International News Service



Propofol's Merit in Total Hip Arthroplasty Dislocation Defended by ...  Mar 28, 2006
CHICAGO, IL -- March 28, 2006 -- The use of propofol as an anesthetic in patients with hip dislocation associated with total hip arthroplasty saves time ... - DG News

Data Raises Questions About Who is Administering Sedation Drug ...  Apr 3, 2006
HARRISBURG, April 3 /US Newswire/ -- Problems associated with the use of a sedation drug called propofol (PRO-pa-fall) have raised concerns about how the drug ... - International News Service

Data Raises Questions about Who is Administering Sedation Drug ...  Apr 3, 2006
Via Thomson Dialog NewsEdge)HARRISBURG, Apr 3, 2006 (US Newswire via COMTEX) --Problems associated with the use of a sedation drug called propofol (PRO-pa-fall ... - TMCnet

Data Raises Questions About Who Is Administering Sedation Drug ...  Apr 3, 2006
Problems associated with the use of a sedation drug called propofol (PRO-pa-fall) have raised concerns about how the drug is administered and monitored ... - Medical News Today

Risky rapid detox vows results  Apr 9, 2006
Bernstein administers propofol, a short-acting anesthetic, and a mixture of medications, including clonidine, a blood pressure medicine. ... - Salt Lake Tribune

Rewarding Patient Investors?  Apr 5, 2006
The company is expected to launch nine or more new drug compounds this year, two of which — Propofol, a generic form of a sedative that AstraZeneca sells as ... - Smartmoney.com

Pediatricians queried on need for more drug information from the ...  Mar 31, 2006
...prescribe atypical antipsychotics. Less than 10% each prescribe buspirone, isotretinoin or propofol. Most pediatricians reported ... - AAP News (subscription)

MGI PHARMA Announces Initiation of Aquavan(R) Injection Pivotal ...  Mar 20, 2006
Aquavan (fospropofol disodium) Injection, a water soluble prodrug formulation of propofol, is a product candidate in development for minimal to moderate ... - Genetic Engineering News

Sachs Associates 5th Annual North American Forum: Investing & ...  Mar 9, 2006
Manhattan Pharmaceuticals is also developing PTH (1-34), a peptide believed to be a regulator of epidermal cell growth, for psoriasis and Propofol Lingual Spray ... - TMCnet

IRadimed Corporation Announces CE, UL, Siemens, and Phillips ...  Mar 22, 2006
IRadimed recently launched its new remote control feature which allows clinicians and physicians to monitor and adjust IVs such as Propofol for sedation while ... - Yahoo! News

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