Recent news on Prothrombin

La Jolla Pharmaceutical company reports Riquent(R) well tolerated ...  -  25 May 2007
PipelineReview.com (press release),Riquent treatment was associated with a dose-dependent increase in activated partial thromboplastin time (aPTT), but not prothrombin time (PT),

Afinion is 'new concept' in point-of-care testing  -  Apr 30, 2007
Laboratory Talk,Tests already available on Afinion include glycated haemoglobin (HbA1c) and C-reactive protein (CRP), with albumin creatinine ratio (ACR) and prothrombin

New Studies Evaluating NEXIUM(R) In Pediatric GERD To Be Presented ...  -  May 22, 2007
PR Newswire (press release),As with all PPIs, patients treated comcomitantly with warfarin may need to be monitored for increases in INR and prothrombin time.

Guidelines Updated for Treatment of Spontaneous Intracerebral ...  -  May 3, 2007
Medscape (subscription)Prothrombin complex concentrate, factor IX complex concentrate, and recombinant activated factor VII normalize the laboratory elevation of the international

Diabetes Mellitus and Hyperglycemia Promote Blood Coagulation ...  -  Apr 27, 2007
AEM (subscription)The relation between diabetes and hyperglycemia and tissue factor procoagulant activity (TF-PCA), plasma factor VIIa (FVIIa), prothrombin fragment 1 + 2

A 10-Year-Old Boy With a 6-Month History of Gingival Bleeding and ...  -  Apr 18, 2007
Medscape (subscription)Prothrombin time at 14.2 seconds and partial thromboplastin time at 35.5 were prolonged, and international normalized ratio was high at 1.32.

Encysive Pharmaceuticals Announces Launch of THELIN (Sitaxentan ...  -  Apr 16, 2007
PharmaLive.com (press release),...dyspepsia, diarrhea, fatigue, muscle cramp, and prothrombin time (PT) prolongation. THELIN is also associated with liver function abnormalities.

Overdoing Niacin Can't Thwart Drug Abuse Tests and Is Risky  -  Apr 12, 2007
Psychiatric Times,The peak prothrombin time was 18.8 seconds for the boy and 23.1 seconds for the girl (normal range 10.3 to 12.8 seconds). The INR peaked at 1.74 on day

Roche Submits Application to the FDA for use of XELOX (Xeloda(R ...  -  Apr 5, 2007
Drug Newswire (press release),Clinically significant increases in prothrombin time (PT) and INR have been observed within days to months after starting Xeloda, and infrequently within

Kent Holtorf, MD, on Treating Chronic Fatigue Syndrome ...  -  Mar 28, 2007
ProHealth's ImmuneSupport.com,This is diagnosed with a specialized laboratory test that includes soluble fibrin monomer, prothrombin fragment 1 +2, fibrinogen and thrombin/antithrombin

Roche Submits Application to the FDA for use of XELOX (Xeloda(R ...  -  27 Mar 2007
PR Newswire (press release),Clinically significant increases in prothrombin time (PT) and INR have been observed within days to months after starting Xeloda, and infrequently within

Merck and Schering-Plough to Develop Another New Cholesterol ...  -  27 Mar 2007
Genetic Engineering News (press release),Warfarin: Simvastatin 20-40 mg/day modestly potentiated the effect of coumarin anticoagulants: the prothrombin time, reported as International Normalized

Ask the Doc  -  Mar 17, 2007
Hindu,Answer: Variation in the Prothrombin time is a usual problem, which patients face when they take oral anticoagulants like Acitrom.

Protein S Deficiency and Lower-Extremity Arterial Thrombosis  -  Mar 16, 2007
Journal of the American Podiatric Medical Association (subscription)The results of coagulation tests (prothrombin time, partial thromboplastin time, international normalized ratio, protein C, and antithrombin III) were

A Pulmonary Embolism Survivor Speaks  -  Mar 15, 2007
ADVANCE for Physician Assistants,He gets monthly blood tests to check his prothrombin international normalized ratio, a measure of the blood's clotting tendencies.

Thelin (sitaxentan sodium) Receives Australian Marketing Approval  -  Mar 7, 2007
PharmaLive.com (press release),...dyspepsia, diarrhea, fatigue, muscle cramp, and prothrombin time (PT) prolongation. THELIN is also associated with liver function abnormalities.

AutoGenomics Receives 510(k) Clearance for INFINITI(TM) Assay for ...  -  Feb 12, 2007
PR Newswire (press release),...thermal cycler, an imager (confocal microscope) with software for detection and genotyping of Factor II (Prothrombin) G20210A and Factor V Leiden G1691A

Use of Recombinant Factor VIIa for Hip Surgery in a Patient with ...  -  Feb 1, 2007
Journal of Bone and Joint Surgery (subscription)During our patient's postoperative period, the prothrombin time and international normalized ratio were within the normal reference ranges except for one

A neonatal presentation of factor V deficiency: A case report  -  Feb 21, 2007
BMC Pediatrics,A coagulation screen showed a prothrombin time of 41s (control 14s), a partial thromboplastin time of 132 s (control 33s) and a normal thrombin time of 15s

Laboratory Evaluation of the Antiphospholipid Syndrome  -  Feb 20, 2007
Annals of Clinical & Laboratory Science (subscription),In the intervening years, it has been established that ß2GPI and other PL-binding proteins such as prothrombin (PT) are relevant antigens in APS and assays

Monitor provides point-of-care anticoagulation testing.  -  Feb 9, 2007
ThomasNet Industrial News Room (press release),...new flexibility and control benefits that healthcare professionals can use to manage in-office prothrombin time (PT/INR) testing more effectively.

Candidate-gene screen finds clotting protein "variants" higher in ...  -  Feb 6, 2007
TheHeart.Org,Variants in factor II (prothrombin) and factor V genes are among those that were already identified as increasing VT risk. Researchers extended the search

Idaho Technology Inc. Receives Exclusive Licensing for 'Monitoring ...  -  18 Jan 2007
Emediawire (press release),Diagnostic kits from other manufacturers using this technology include Factor V Leiden, Prothrombin polymorphisms, and the detection of pathogens associated

Fish Oil Fights Coagulation Factors in Heart Disease  -  Jan 3, 2007
Natural Products Industry Insider,In both studies, multivariate analysis indicated a strong clustering of fasting concentrations of triacylglycerols, prothrombin, factor V, factor VII and

Nuvelo Initiates Phase 2 Trial Of RNAPc2 In Patients With ...  -  Jan 6, 2007
Medical News Today (press release),In addition, rNAPc2 suppressed F1+2 and prolonged the prothrombin time, both in a dose-related fashion. mCRC is the second leading cause of cancer-related

Activation of protein C and hemodynamic recovery after coronary ...  -  Jan 5, 2007
The Journal of Thoracic and Cardiovascular SurgeryActivated protein C, protein C, prothrombin fragment F1+2 (a marker of thrombin generation), and D-dimer (a marker of fibrinolysis) levels were measured

Nuvelo Initiates Phase 2 Trial of rNAPc2 in Patients with ...  -  Jan 4, 2007
PR Newswire (press release),In addition, rNAPc2 suppressed F1+2 and prolonged the prothrombin time, both in a dose-related fashion. About Metastatic Colorectal Carcinoma mCRC is the

Total Joint Arthroplasty: When Do Fatal or Near-Fatal ...  -  Jan 2, 2007
Journal of Bone and Joint Surgery (subscription)Daily laboratory tests, including complete blood-cell count, renal function tests, blood chemistry, prothrombin time, and international normalized ratio,

Palliative Care for Frail Older Adults: "There Are Things I Can't ...  -  Dec 26, 2006
Journal of American Medical Association (subscription),I would check her prothrombin time and INR [international normalized ratio], and her sodium and her potassium as well because she was receiving lots of

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),Warfarin: Simvastatin 20-40 mg/day modestly potentiated the effect of coumarin anticoagulants: the prothrombin time, reported as International Normalized

Xeloda(R) Combination Meets Primary Endpoint In International ...  -  Dec 24, 2006
Medical News Today (press release),Clinically significant increases in prothrombin time (PT) and INR have been observed within days to months after starting Xeloda, and infrequently within

Palliative Care for Frail Older Adults: "There Are Things I Can't ...  -  26 Dec 2006
Journal of American Medical Association (subscription),I would check her prothrombin time and INR [international normalized ratio], and her sodium and her potassium as well because she was receiving lots of

Studies Offer Better Options to Treat Patients With Hematologic ...  -  Dec 11, 2006
PR Newswire (press release),Natural Course of the Subsequent Pregnancy after a Single Loss in Women with and without the Factor V Leiden or Prothrombin 20210A Mutations [Abstract #275]

Clinical: Anticoagulation therapy  -  Dec 7, 2006
Therapeutics Daily (subscription) (press release),Enzyme inducers, such as barbiturates, rifampicin and carbamazepine can increase metabolism. Measurement of the prothrombin time is one way to monitor

IVMD Inc. Reports Showcase of New Technology at Medica a Major Success  -  Dec 7, 2006
MacReport (press release),Many companies show new technology at Medica, but the example of our Prothrombin reader previously developed for Inverness Medical Innovations clearly sets

Studies Offer Better Options to Treat Patients With Hematologic ...  -  Dec 11, 2006
PR Newswire (press release),Factor V Leiden and prothrombin 20210A are two inherited DNA mutations essential for appropriate clotting response in case of injury to blood vessels.

Xeloda(R) Combination Meets Primary Endpoint In International ...  -  Dec 24, 2006
Medical News Today (press release),Clinically significant increases in prothrombin time (PT) and INR have been observed within days to months after starting Xeloda, and infrequently within

Vitamin K1 Prophylaxis May Be Helpful in Preterm Infants  -  Dec 11, 2006
Medscape (subscription)The investigators evaluated 3 prophylactic regimens using undercarboxylated prothrombin, a protein induced in vitamin K absence/antagonism (PIVKA-II),

Greater LDL Cholesterol Reduction with VYTORIN Compared to Lipitor ...  -  Dec 21, 2006
Business Wire (press release),Warfarin: Simvastatin 20-40 mg/day modestly potentiated the effect of coumarin anticoagulants: the prothrombin time, reported as International Normalized

Encysive Pharmaceuticals Announces Launch of Thelin in Germany  -  Dec 18, 2006
PharmaLive.com (press release),...dyspepsia, diarrhea, fatigue, muscle cramp, and prothrombin time (PT) prolongation. THELIN is also associated with liver function abnormalities.

Decreased Bleeding Frequency With Secondary Prophylactic Use Of ...  -  Dec 13, 2006
Medical News Today (press release),...advanced atherosclerotic disease, crush injury, septicemia, or concomitant treatment with activated or nonactivated prothrombin complex concentrates

IVMD, Inc. Announces Substantial Progress in Intellectual Property ...  -  Dec 7, 2006
Market Wire (press release)The company has already gained valuable clinical trials experience from two projects in its portfolio, a prothrombin monitor (licensed to Inverness Medical

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