Recent news on Riluzole

Commencement of phase Ib clinical study for Myogane  -  May 17, 2007
Checkbiotech.org (press release),Riluzole (Rilutek(tm)), a glutamate modulator, is the only agent indicated for the treatment of this condition and increases average survival by only a few

Can being fit raise your risk of motor neurone disease?  -  Apr 17, 2007
Daily Mail,...expectancy for someone with MND is five years. There is no cure, although drugs such as riluzole can extend the extended survival rate by about six months.

Red Herring’s Bioscience Report  -  Feb 4, 2007
Red Herring,But right now, Aventis Pharmaceuticals’ Riluzole is the only US FDA-approved drug to treat the disease. The problem with Riluzole is that it only extends

A life without fear  -  Feb 11, 2007
Seattle Times,Treatment: There is only one FDA-approved drug to treat ALS: riluzole. It extends life for up to a few months. A one-month dosage costs around $1000.

New treatment holds promise for potential ALS sufferers  -  Jan 30, 2007
Ottawa Citizen (subscription),Only one was found to have a modest effect, Rilutek (riluzole). It seems to prolong patients’ survival by about three months.

United States: Prior Art Need Not Be "Effective" To Be Enabling ...  -  Jan 8, 2007
Mondaq News Alerts (subcription),Riluzole is the chemical compound 6-trifluoromethoxy-2-benzothiazolamine, which is sold by Aventis under the trade name Rilutek® for treatment of

ALS patients become prisoners in their bodies  -  Jan 7, 2007
Salt Lake Tribune,Patients who can afford to take Rilutek, or the generic riluzole, generally live for an extra three to five months, the doctor explains.

Fighting for Time  -  Dec 25, 2006
Press-Enterprise (subscription),Riluzole, the only medication prescribed for ALS, offers only to prolong survival by a small handful of months. De Luca is not taking Riluzole.

Pete's anguish over debilitating disease  -  Dec 30, 2006
Bridgwater Mercury,He is taking a rare drug - called Riluzole - to slow down the crippling effect of the incurable disease, which causes stomach cramps, speech problems,

Waging Lou Gehrig’s Ultimate Fight  -  Jan 16, 2007
Red Herring,So far, only one drug, Aventis Pharmaceuticals’ Riluzole, has been federally approved to treat the disease. But the therapeutic effects are modest,

Delving into depression  -  Jan 1, 2007
New Haven Register (subscription),A drug called riluzole, which is already used to treat Lou Gehrig’s disease, can increase the uptake of glutamate and could possibly normalize its release,

Trophos Successfully Completes Phase Ib ALS Clinical Trials for ...  -  Dec 7, 2006
PharmaLive.com (press release),In healthy volunteers, TRO19622 exposure levels were approximately 30% higher after repeated dosing with riluzole for which bioequivalence was shown before and ...

Marijuana-like Drugs Help Treatment of Nervous System Diseases  -  Dec 1, 2006
Sofia News Agency,...survival. That's a significant improvement over the only existing ALS drug, riluzole, which extends life by two months. Researchers ...

Experts discuss ALS research  -  Nov 25, 2006
Richmond Review,...physicians.�. Although Riluzole has recently been approved as a treatment for ALS patients, there is no cure for the disease. Scientists ...

Huntington's Disease :: Memantine and riluzole are potential ...  Oct 30, 2006
...cultured cells provides an effective way to screen drugs against Huntington's disease and shows that two compounds – memantine and riluzole – are most ... -SpiritIndia, Test reveals effectiveness of potential Huntington's disease drugs  Oct 30, 2006
Jun Wu, research associate, have shown an effective test for screening Huntington's disease drugs and that two compounds -- memantine and riluzole -- are most ... -PhysOrg.com, NARSAD Hosts 18th Annual New York Mental Health Symposium, Oct. ...  Oct 26, 2006
Professor of Psychiatry, Yale University School of Medicine, and Assistant Professor, Boonshoft School of Medicine, Dayton, Ohio Role of riluzole in modulating ... -PR Newswire (press release), NARSAD Hosts 18th Annual New York Mental Health Symposium, Oct. ...  Oct 26, 2006
A newly emerging class of medications that includes riluzole, a drug previously approved for use in the treatment of Amyotrophic Lateral Sclerosis (ALS ... -Earthtimes.org After years of helping others, advocate faces own illness  Oct 28, 2006
...winter. She'll keep traveling as long as she can, Appleby says. She is taking Riluzole, the only approved drug for ALS symptoms. "I ... -Rochester Democrat and Chronicle, Avicena Announces Completion Of Patient Enrollment For The First ...  Oct 19, 2006
Investigators will also assess whether the combination drug candidates are safe and well tolerated in conjunction with riluzole, the only FDA-approved ALS drug ... -Medical News Today (press release), IMPAX Announces Court of Appeals Remands Earlier Riluzole Patent ...  -  Nov 22, 2006
Business Wire (press release),Appeals for the Federal Circuit ruled that the district court had erred in deciding, after trial, that the patent relating to the use of riluzole in treating ...

Trophos Successfully Completes Phase Ib ALS Clinical Trials for ...  -  Dec 7, 2006
PharmaLive.com (press release),In healthy volunteers, TRO19622 exposure levels were approximately 30% higher after repeated dosing with riluzole for which bioequivalence was shown before and ...

Marijuana-like Drugs Help Treatment of Nervous System Diseases  -  Dec 1, 2006
Sofia News Agency,...survival. That's a significant improvement over the only existing ALS drug, riluzole, which extends life by two months. Researchers ...

Impax pharma gets boost from Appeals Court ruling  -  Nov 22, 2006
San Jose Business Journal,Hayward-based Impax (OTCBB:IPXL) said the patent relates to the use of riluzole in treating amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's ...

Impax wins legal round on drug  -  Nov 20, 2006
San Jose Mercury News,The patent covers a method of using a compound called riluzole to treat amyotrophic lateral sclerosis, a fatal disease of the central nervous system also known ...

Experts discuss ALS research  -  Nov 25, 2006
Richmond Review,...physicians.�. Although Riluzole has recently been approved as a treatment for ALS patients, there is no cure for the disease. Scientists ...

Testing Drugs to Treat Huntington’s 11/14/06  -  Nov 13, 2006
Genomics & Proteomics,...s disease, say scientists at University of Texas Southwestern Medical Center, Dallas, who found that two compounds—memantine and riluzole—are most ...

Cause of ALS yet unknown; cure is far off  Aug 20, 2006
Riluzole (Rilutek), the first and only medication to be approved by the Food and Drug Administration for treatment of ALS, has been shown in research studies ... -Fort Wayne Journal Gazette

Chronic Depression in Bipolar Disorder  Jul 28, 2006
JA, Sing JB, Denicoff KD, De Jesus G, Luckenbaugh DA, Charney DS, Manji HK: An open-label trial of the glutamate-modulating agent riluzole in combination with ... -Am J Psychiatry (subscription)

Dealing with MND one day at a time  Jun 26, 2006
As yet doctors have no idea what causes the disease, there is no cure and the only treatment, a drug called riluzole or Rilutek, has only a small chance of ... -Scotsman



A Twitch of Potential  Apr 23, 2006
...implicated a genetic mutation in a small subset of MND patients, and the pharmaceutical company Rhone-Poulenc Rorer launched riluzole (Rilutek), the first ... - TIME

Faust Pharmaceuticals announces Phase IIa results for ALS  Apr 26, 2006
...to acquire data on FP0011 patient tolerance and safety, and to check whether it was possible to administer FP0011 in combination with riluzole, currently the ... - PharmaLive.com

Cutting-Edge Research on Repair of Spinal Cord Injuries Presented ...  May 1, 2006
...the authors present several promising medications under investigation for protecting and promoting neurologic function, including riluzole, minocycline, and ... - Genetic Engineering News

More than 160 Medicines to Treat Rare Diseases Approved in Last ...  Apr 20, 2006
For instance, after 126 years, a breakthrough treatment—Rilutek® (riluzole)—was approved for treatment of amyotrophic lateral sclerosis, or ALS, in 1995. ... - PharmaLive.com





Drug Shows Promise Against Lou Gehrig's Disease, OK Medical ...  Mar 29, 2006
The disease results in the gradual loss of motor function and is always fatal. Riluzole is the only drug approved by the Food and Drug Administration for ALS. ... - International News Service

Help grant a dying wish  Mar 30, 2006
A combination of Riluzole, the only drug to slow the fatal disease, non-invasive breathing devices and a team palliative approach to addressing the effects of ... - North Shore Times

Support research on ALS treatment  Apr 1, 2006
These studies have identified one drug, riluzole that is part of current ALS therapy. The outlook for patients with ALS is better than it was 20 years ago. ... - Jackson Clarion Ledger

Province called on to cover costs for ALS drug  Apr 3, 2006
The cause of ALS is cause is not known and there's no cure, although a new drug, riluzole – also called Rilutek – helps slow down the onset of symptoms. ... - CBC.ca

Thalidomide, Lenalidomide show promise against Lou Gehrig's ...  Mar 9, 2006
While one drug, Riluzole, can alleviate symptoms and extend survival by perhaps a few months, there is no effective treatment for this uniformly fatal illness. ... - News-Medical.net



Families struggle with ALS  Mar 2, 2006
Present treatment of ALS includes one drug, riluzole (Rilutek) and is aimed at symptomatic relief, prevention of complications and maintenance of maximum ... - New Canaan Advertiser,

Treatment-Resistant Bipolar Depression: A STEP-BD Equipoise ...  Feb 9, 2006
...to the combination of olanzapine and fluoxetine (21), switching to quetiapine (22), or adding novel treatments such as pramipexole (23, 24) or riluzole (25). ... - Am J Psychiatry (subscription)

Treatment-Resistant Bipolar Depression: A STEP-BD Equipoise ...  09 Feb 2006
...to the combination of olanzapine and fluoxetine (21), switching to quetiapine (22), or adding novel treatments such as pramipexole (23, 24) or riluzole (25). ... - Am J Psychiatry (subscription)

Research reveals pesticide, disease link  Feb 2, 2006
...disease. He said the only treatment at the moment was a drug called riluzole which increased a person's lifespan by "a few months". ... - The Age

Fighting back against ALS  Jan 14, 2006
At present, ALS is totally untreatable; there is only one drug - known commercially as Rilutek and generically as riluzole - that has been approved by the US ... - Jerusalem Post

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