Recent news on Selectin

Subendothelial Heparan Sulfate Proteoglycans Become Major L ...  -  25 May 2007
Am J Pathology (subscription)In this model, the leukocyte adhesion molecule L-selectin and its ligands expressed on inflamed endothelial cells are involved in leukocyte rolling.

The Role of Platelets in Leukocyte Recruitment in Chronic Contact ...  -  25 May 2007
Am J Pathology (subscription)Flow cytometry showed increased P-selectin expression on platelets and an increased number of platelet-leukocyte aggregates in blood of repeatedly elicited

CTI Announces Completes Enrollment of Phase II Trial in the US ...  -  May 8, 2007
PharmaLive.com (press release),YSPSL is a recombinant molecule resulting from the fusion of P-selectin glycoprotein ligand (PSGL) and human IgG1. CTI is managing the clinical trial

Cognitive Decline After Heart Surgery And Inflammatory System ...  -  May 6, 2007
Medical News Today (press release),The researchers found that patients with variants in genes for C-reactive protein and P-selectin were less likely to suffer cognitive decline than were

Genes Involved in Inflammatory System Also Inhibit Cognitive ...  -  May 2, 2007
Genetic Engineering News (press release),They found that patients with the variation of the C-reactive protein gene were 20.6% less likely to suffer mental decline and those with the P-selectin

Y's Therapeutics Initiates Phase II Trial With YSPSL in Liver ...  -  May 3, 2007
PipelineReview.com (press release),YSPSL is a recombinant molecule resulting from the fusion of P-selectin glycoprotein ligand (PSGL) and human IgG1. During I/R, P-selectin appears on the

Faithful Mimic of Proteins  -  Apr 29, 2007
Chemical & Engineering NewsIts target, P-selectin, is involved in the inflammatory response. Previous studies have shown that two PTMs are key to PSGL-1's function.

For sale: Stem cell enhancers  -  May 15, 2007
Scientist,Drapeau said he has tested one of the compounds in humans, and it acts as a blocker of L-selectin, a cell adhesion molecule. Drapeau said the compounds are

StemEnhance Facts ~ An FAQ on StemEnhance  -  May 14, 2007
PRLog.Org (press release),One extract, which contains an L-selectin ligand, supports the natural release of stem cells (CD34+ cells) from the bone marrow.

Phase-Dependent Roles of E-Selectin during Chronic Contact ...  -  Apr 24, 2007
Am J Pathology (subscription)Elicitation with oxazolone on the ears of P-selectin –/– mice 7 days after the sensitization induced a typical delayed-type hypersensitivity response

Y's Therapeutics Completes Enrollment of Phase II Trial in the US ...  -  Apr 24, 2007
PipelineReview.com (press release),YSPSL is a recombinant molecule resulting from fusion of P-selectin glycoprotein ligand (PSGL-1) and human IgG1. The underlying cause of DGF is

The Host Inflammatory Response Promotes Liver Metastasis by ...  -  Apr 24, 2007
Am J Pathology (subscription)E-selectin expression was evident mainly on sinusoidal vessels by 6 and 10 hours, respectively, following H-59 and CX-1 inoculation, and this corresponded

Magnesium intake and plasma concentrations of markers of systemic ...  -  Apr 5, 2007
Am J Clin Nutr (subscription),Plasma concentrations of C-reactive protein (CRP), interleukin 6 (IL-6), soluble tumor necrosis factor receptor 2 (sTNF-R2), E-selectin,

BUYINS.NET: VNX, ADAM, ASMI, BLSI, CTIB, ENCY Have Been Added To ...  -  Apr 3, 2007
Insurance News Net,...including TBC3711, second-generation endothelin receptor antagonist; TBC4746, an oral VLA-4 antagonist; and bimosiamose, a selectin antagonist.

Autoantibodies to Vimentin Cause Accelerated Rejection of Cardiac ...  -  Mar 27, 2007
Am J Pathology (subscription)...adjuvant mice demonstrated increased numbers of T cells and enhanced microvascular deposition of C3d, CD41, and P-selectin compared with controls.

C-Reactive Protein Levels Predict Skeletal-Related-Event Survival ...  -  27 Mar 2007
DG NewsSixteen potential biomarkers were monitored: IL-1alpha, IL-1beta, IL-2, IL-6, IL-8 and IL-10, TNFalpha, EGF, VEGF, MCP-1, sE-Selectin, s-ICAM-1, s-VCAM-1,

Silent Strokes Linked to Sleep Apnea  -  Mar 15, 2007
MedPage Today,The researchers also measured the levels of soluble CD40 ligand (sCD40L) and soluble P-selectin (sP-selectin), proteins regarded as precursors of

Silent Brain Infarction and Platelet Activation in Obstructive ...  -  Mar 6, 2007
AJRCCM (subscription),Objectives: The aim of this study was to evaluate whether SBI and serum levels of sCD40L and sP-selectin are increased in patients with obstructive sleep

Treatment of Periodontitis and Endothelial Function  -  Feb 28, 2007
New England Journal of Medicine (subscription),However, flow-mediated dilatation was greater and the plasma levels of soluble E-selectin were lower in the intensive-treatment group than in the

New Immune Cell Exit Strategy Discovered  -  Mar 5, 2007
Playfuls.com,Lymphocytes use a protein called L-selectin to recognize and grasp specific types of complex sugars called O-glycans displayed on inflamed blood vessel

Obstructive sleep apnea patients show silent brain infarction  -  Mar 19, 2007
Hindu,Two important proteins called soluble C40 ligand and soluble P-selectin are markers of platelet activation and appear to forecast future cerebrovascular

CPAP Reduces Levels of C-Reactive Protein Treating Obstructive ...  -  Mar 16, 2007
Best Syndication,These proteins are C40 ligand and soluble P-selectin, which are markers of platelet activation and appear to forecast future cerebrovascular events.

Intensive Treatment of Periodontal Disease Improves Endothelial ...  -  Mar 1, 2007
Medscape (subscription)However, flow-mediated dilatation was significantly greater and plasma levels of soluble E-selectin significantly lower 60 and 180 days after therapy in the

Treating Dental Disease Improves Vascular Function  -  Feb 28, 2007
MedPage Today,Thereafter, soluble E-selectin was lower in the intensive-treatment group (at two months P=0.02 and at six months after therapy P=0.03) and serum C-reactive

Pearl Jam Headline Lollapalooza Rockin like it's 1992  -  Mar 2, 2007
Crave Online,Vedder and c. are bked fr thirteen Eurpean shws this summer, mst f them festivals. They will fllw the tur with a selectin f US dates befre playing

Prediabetes Gives Women Head Start on Heart and Diabetes Risk  -  Feb 22, 2007
MedPage Today,No difference in waist circumference (P=0.056), inflammatory marker C-reactive protein levels (P=0.056), interleukin-6 (P=0.762), E-selectin (P=0.062),

A Role for Type 1 Corticotropin-Releasing Hormone Receptors in ...  -  Feb 23, 2007
Am J Pathology (subscription)...patient cohort (n = 9) established that expression of CRH-R1 significantly (P < 0.03) colocalized with PECAM-1 and E-selectin expression in vivo.

Alteon's Alagebrium Demonstrates Cardiovascular Activity In ...  -  Feb 16, 2007
PipelineReview.com (press release),The increase in FMD correlated with a decrease in markers of collagen synthesis, p-selectin and intracellular cell adhesion molecule (all P is less than

Stem cell device could have role in cancer treatment  -  Jan 10, 2007
DrugResearcher.com,The new technology uses selectin molecules, which have a higher affinity for stem and cancer cells than other cells, to slow down the flow of specific cells

Cancer-Killing Invention Also Harvests Stem Cells  -  Jan 8, 2007
Medical News Today (press release),He also realized that selectin is the adhesive mechanism by which bone marrow stem cells leave the bloodstream and find their way back into bone marrow.

Study findings from Turkey, the United States and Canada provide ...  -  Jan 4, 2007
Therapeutics Daily (subscription) (press release),Study 1: Tissue expression of the adhesion molecules E-selectin and P-selectin is significantly correlated with left atrial and left ventricular chamber

Lake Region Runner Signs With PHCC  -  Jan 6, 2007
The Ledger,A first-team All-County selectin, Spurlin finished fifth in the county, fifth in district, 19th in regionals and 67th (out of 180 runners) in the state meet

American Journal of Clinical Nutrition, Vol. 85, No. 1, 293S-299S ...  -  Jan 5, 2007
Am J Clin Nutr (subscription),...-Tocopherol also decreases monocyte-endothelial cell adhesion in vitro, which correlates with decreased endothelial cell E-selectin expression (17) and

Platelets Key To Acute Lung Injury  -  Dec 6, 2006
Medical News Today (press release),Mechanistically, expression of a molecule known as P-selectin by the platelets was crucial for mediating the platelet-neutrophil interaction, which induced

This site is for informational purposes only--it does not offer medical advice or sell health products. If you need assistance, contact your physician or healthcare professional