Recent news on Tegaserod

Theravance Reveals Results From Preclinical Research And Phase 1 ...  -  25 May 2007
Trading Markets,In vitro studies that compared TD-5108 with tegaserod demonstrated TD-5108's greater selectivity for 5-HT4 receptors over other 5-HT receptor types,

WHAT TO TELL YOUR PATIENTS Health Canada nixes constipation med ...  -  Apr 26, 2007
National Review of Medicine,The constipation drug tegaserod has been pulled off the shelves after researchers discovered an increased cardiac risk — including MI and stroke — in

DDW: Lubiprostone Effective in Irritable Bowel Syndrome  -  May 22, 2007
MedPage Today,The report came after Novartis halted sales on March 30 of tegaserod (Zelnorm), its agent for irritable bowel syndrome and constipation,

AGS: Geriatricians Go Slow with Newer Chronic Constipation Therapies  -  May 8, 2007
MedPage Today,The 5-HT 4 agonist tegaserod (Zelnorm) was taken off the market on March 30 after 13 patients developed life-threatening cardiovascular events while on the

Drug Risks and Free Speech — Can Congress Ban Consumer Drug Ads?  -  May 2, 2007
New England Journal of Medicine (subscription),In February, Novartis submitted a review to the FDA that pooled data from 29 clinical trials of Zelnorm (tegaserod), its drug for women with irritable bowel

ActiveHealth Identifies Close to 10000 Patients Taking Pergolide ...  -  Apr 4, 2007
PharmaLive.com (press release),1) This compares to a 0.1% absolute risk of adverse cardiac events in patients taking tegaserod (13 out of 11614 patients analyzed in 29 clinical studies).

SFDA does not pull Novartis IBS drug from shelves despite FDA ban  -  Apr 18, 2007
Interfax.cn (subscription),Zelnorm, which is the trademark for the generic drug tegaserod maleate, is a prescription drug recommended for the short-term treatment of irritable bowel

Drug Zelmac recalled  -  Apr 19, 2007
The Nation Newspaper,THE SALE and distribution of the drug, tegaserod, branded as Zelmac in Barbados and Zelnorm in the United States, has been suspended by its manufacturers.

Novartis suspends Canadian marketing and sales of Zelnorm(R) in ...  -  Mar 30, 2007
CNW Telbec (Communiqués de presse),Results obtained from multiple mechanistic studies do not suggest any arterial vasoconstrictive effects of tegaserod. "My review of the data suggested that

Novartis suspends US marketing and sales of Zelnorm(R) in response ...  -  Mar 31, 2007
PipelineReview.com (press release),..."My review of the data suggested that a causal relationship is unlikely between tegaserod and the rare cardiovascular ischemic events observed in clinical

IBS drug Zelmac banned from sale in Australia  -  Apr 8, 2007
SpiritIndia,The drug tegaserod maleate, marketed under the name Zelmac, was taken off the market in the United States a few days ago.

Marketing of Zelnorm Suspended; Drug Linked to Slight Increase in ...  -  Mar 30, 2007
Medscape (subscription)It also noted that no effect of tegaserod maleate on the coronary arteries was seen in preclinical and clinical testing. Quoted in a company press release

FDA tells Novartis to stop selling IBS drug Zelnorm over possible ...  -  Apr 2, 2007
Pharma Times (subscription),The US Food and Drug Administration asked Novartis to suspend US marketing of Zelnorm (tegaserod), known as Zelmac in Switzerland, Latin America and the

Novartis Suspends US Marketing and Sales of Zelnorm in Response to ...  -  Mar 30, 2007
eMaxHealth.com,Novartis is complying with a request from the Food and Drug Administration (FDA) to suspend US marketing and sales of Zelnorm(R) (tegaserod maleate),

Cumberland Pharmaceuticals Offers Alternative to Zelnorm  -  Apr 25, 2007
PharmaLive.com (press release),Zelnorm (tegaserod maleate) was approved by the Food and Drug Administration in 2004 for treatment of patients younger than 65 suffering from chronic

Sales halted for constipation drug  -  Mar 31, 2007
Brocktown News,Zelnorm, also called tegaserod maleate, is a prescription medication approved for short-term treatment of women with irritable bowel syndrome with

FDA Announces Discontinued Marketing of GI Drug, Zelnorm, for ...  -  Mar 31, 2007
SolancoNews.com,...voluntarily discontinue marketing of Zelnorm (tegaserod) based on the recently identified finding of an increased risk of serious cardiovascular adverse

Constipation drug pulled off the market  -  Mar 30, 2007
Dallas Morning News (subscription),Zelnorm, also called tegaserod maleate, is approved for short-term treatment of women with irritable bowel syndrome with constipation and for patients

Novartis Slumps after Pulling Zelnorm  -  Mar 31, 2007
domain-B,..."Furthermore, the data did not show any consistent pattern of event type, time to event or dose relationship in tegaserod-treated patients."

Novartis Pulls Constipation Drug Linked To Increased Risk Of Heart ...  -  Mar 30, 2007
All Headline NewsAccording to the FDA, patients using Zelnorm, also called tegaserod maleate, are advised to contact their health care providers to switch over to

Sales suspended for anti-constipation drug  -  Mar 30, 2007
CBC News,Novartis is stopping sales of Zelnorm, also called tegaserod maleate, in Canada and the US at the request of regulators.

Constipation Drug Pulled From Market  -  Mar 30, 2007
Therapeutics Daily (subscription) (press release),...and Drug Administration, said during a teleconference. Zelnorm (generic name tegaserod maleate) was first approved by the FDA in 2002 for the short-term

Novartis Suspends US Marketing and Sales of Zelnorm(R) in Response ...  -  Mar 30, 2007
Therapeutics Daily (subscription) (press release),US marketing and sales of Zelnorm(R) (tegaserod maleate), a treatment for irritable bowel syndrome (IBS) with constipation and chronic constipation.

Novartis off to a flyer in 2007 thanks to Diovan and Gleevec  -  Apr 24, 2007
Pharma Times (subscription),On the negative side, revenue from the irritable bowel syndrome treatment Zelnorm/Zelmac (tegaserod), sales of which have just been suspended in the USA and

Biofeedback for Chronic Constipation?  -  Apr 17, 2007
HealthandAge.comOne of the more successful medications in use, up to a few weeks ago, was tegaserod (Zelnorm®), but it has recently been withdrawn from the market because

Vendor Notebook: US Army awards contract to Cogon  -  Apr 15, 2007
Healthcare IT News,...used to treat Parkinson’s disease, and tegaserod (Zelnorm), used for short-term treatment of constipation in irritable bowel syndrome.

IBS Medication Withdrawn  -  Apr 10, 2007
CNW Telbec (Communiqués de presse),...medication Zelnorm(TM) (tegaserod hydrogen maleate) was withdrawn from the market to permit further evaluation of important safety information.

Suspended – sale of drug to treat IBS  -  Apr 2, 2007
Malaysia Star,The medication Zelmac (tegaserod maleate), which is marketed in the United States under the brand name Zelnorm, has been found by the Food and Drug

Novartis shares drop after Zelnorm sales stop, profit warning  -  Apr 2, 2007
Canada.com,Zelnorm, also called tegaserod maleate, was pulled off the US market at the request of the Food and Drug Administration after being linked to increased

Novartis suspends US marketing and sales of Zelnorm  -  Apr 2, 2007
SpiritIndia,Novartis is complying with a request from the Food and Drug Administration (FDA) to suspend US marketing and sales of Zelnorm (tegaserod maleate),

Zelnorm withdrawn  -  Apr 2, 2007
Cay Compass,Zelnorm, also called tegaserod maleate, is a prescription medication approved for short–term treatment of women with irritable bowel syndrome with

AD takes drugs off market  -  Apr 2, 2007
AME Info,Tegaserod - marketed as Zelmac in the UAE - is prescribed for short-term treatment of women with irritable bowel syndrome. Replication or redistribution in

FDA Asks Novartis to Suspend Marketing of GI Drug Zelnorm  -  Apr 2, 2007
Newsinferno.com,The US Food and Drug Administration (FDA) notified Novartis Pharmaceuticals Corporation that the company must cease its marketing of Zelnorm (tegaserod),

Marketing and Sales Suspension Notice for Zelnorm Tablets, 6 mg  -  Apr 2, 2007
DG NewsOTTAWA, CANADA -- April 2, 2007 -- At Health Canada's request, Novartis Pharmaceuticals Canada Inc. is suspending marketing and sales of Zelnorm* (tegaserod

Novartis Pulls Zelnorm in US, Cuts 2007 Outlook  -  Apr 1, 2007
CNBC,Zelnorm, known generically as tegaserod, had a rocky path to its 2002 US approval. The FDA rejected Novartis' initial bid in 2001 and requested more data on

Medical Monday: FDA Says Makers of Zelnorm Will Stop Marketing ...  -  Apr 1, 2007
HNN Huntingtonnews.net,2007 that Novartis Pharmaceuticals Corp. of East Hanover, New Jersey will suspend marketing of the drug Zelnorm (tegaserod) in the United States based

Constipation Drug Pulled From Market  -  Mar 30, 2007
Atlanta Journal Constitution (subscription),Zelnorm (generic name tegaserod maleate) was first approved by the FDA in 2002 for the short-term treatment of women with irritable bowel syndrome whose

FDA Asks Swiss Pharmaceutical Company To Stop Selling Constipation ...  -  Mar 31, 2007
Free Internet Press,Zelnorm, also called tegaserod maleate, is a prescription medication approved for the short-term treatment of women with irritable bowel syndrome,

Irritable Bowel Syndrome Drug Zelnorm Taken Off Market  -  Mar 31, 2007
Toronto Daily News,Food and Drug Administration. Novartis press statement, March 30, 2007. FDA: "Public Health Advisory: Tegaserod maleate (marketed as Zelnorm)."

Zelnorm Recall Will Affect Thousands  -  Mar 30, 2007
CBS2 Chicago,..."One of the nice things about Zelnorm, which is also known as tegaserod, was that it worked fast and it had a consistent effect in patients who responded to

Novartis Suspends Canadian Marketing And Sales Of Zelnorm In ...  -  Mar 30, 2007
Trading Markets,Results obtained from multiple mechanistic studies do not suggest any arterial vasoconstrictive effects of tegaserod. Zelnorm received Health Canada

Zelnorm – Popular GI Drug – Stops Marketing, Says FDA  -  Mar 30, 2007
SeniorJournal.com,...and Novartis Pharmaceuticals agreed, that marketing of Zelnorm (tegaserod) should be discontinued. Novartis said it would suspend marketing of the drug

FDA: Zelnorm Being Pulled From Market  -  Mar 30, 2007
DG News2007 -- FDA is issuing this public health advisory to inform patients and health care professionals that the sponsor of Zelnorm (tegaserod maleate),

US Zelnorm Sales and Marketing Suspended  -  Mar 30, 2007
Facts and Comparisons,Novartis is suspending the US sales and marketing of its product Zelnorm (tegaserod maleate), indicated for irritable bowel syndrome with constipation and

Zelnorm Read Before You Buy, Zelnorm Online Posted By : Quinn -  -  Feb 17, 2007
Business Portal 24 (press release),Its important to know you can find some great buys on Zelnorm {Tegaserod Maleate} at many online websites. But lately weve been seeing a growing trend by a

Premium-Priced Agents from Novartis, Alizyme, and Astellas Will ...  -  Feb 5, 2007
PR Newswire (press release),The new Pharmacor report "Irritable Bowel Syndrome" finds that the uptake of Novartis' Zelmac/Zelnorm (tegaserod) and the launches of other high-priced

Novartis officials summarized the newest activities  -  Jan 11, 2007
Therapeutics Daily (subscription) (press release),Report 1: Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia.

Gastrointestinal Medications  -  Jan 5, 2007
Psychosomatics (subscription)Tegaserod is a selective serotonin 5-HT 4 receptor partial antagonist with promotile activity, used in the treatment of constipation and abdominal

Long-Term Tegaserod Safe, Effective Treatment for Chronic Constipation  -  Dec 8, 2006
Medscape (subscription)December 8, 2006 — Tegaserod (Zelnorm) used for up to 16 months is a safe, well tolerated, and effective treatment for patients with chronic constipation,

Suffering From Chronic Constipation?  -  Nov 27, 2006
Science Daily (press release)New research has found that a new medication, tegaserod, is effective in treating nearly all symptoms associated with chronic constipation (CC),

Just Released: Science Closer To Fart Cure  -  Nov 27, 2006
DigitalJournal.com,The drug, named Tegaserod, also helps alleviate flatulence and bloating. The smell of a new day on the horizon has the world breathing easier.

Guthrie names chairman of Surgery Department  -  Dec 10, 2006
Elmira Star-Gazette,He was recently awarded a grant from the Guthrie Research Foundation to study and define the safety and efficacy of Zelnorm (tegaserod) use to reduce the

New medications for constipation have merit, but may be unnecessary  -  Nov 30, 2006
Savannah Morning News,Lactulose, polyethylene glycol 3350 commercially known as MiraLax, tegaserod commercially known as Zelnorm, and the new medication lubiprostone commercially

AbelsonTaylor Expands DTC Capabilities  -  Nov 27, 2006
PharmaLive.com (press release),...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis.

New Data for Tegaserod maleate Demonstrate Relief of Multiple ...  Oct 24, 2006
LAS VEGAS, NV -- October 24, 2006 -- Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia ... -DG News New Zelnorm® Data Demonstrate Relief Of Multiple Symptoms Of ...  Nov 3, 2006
The gastrointestinal medicine Zelnorm® (tegaserod maleate) has demonstrated potential benefits in helping patients with the multiple symptoms of a common ... -Medical News Today (press release), New Data for Zelnorm(R) Demonstrate Relief of Multiple Symptoms of ...  Oct 25, 2006
23 /PRNewswire-FirstCall/ -- Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia, according to ... -Drug Newswire (press release), New Zelnorm® data demonstrate relief of multiple symptoms of  Oct 23, 2006
Basel, October 23, 2006 - The gastrointestinal medicine Zelnorm® (tegaserod maleate) has demonstrated potential benefits in helping patients with the multiple ... -WebWire (press release), New Zelnorm(R) data demonstrate relief of multiple symptoms of ...  Oct 24, 2006
BASEL, Switzerland | Oct 23, 2006 | The gastrointestinal medicine Zelnorm® (tegaserod maleate) has demonstrated potential benefits in helping patients with ... -PipelineReview.com (press release), New Data For Zelnorm(R) Demonstrate Relief Of Multiple Symptoms Of ...  Oct 24, 2006
Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia, according to new data being presented ... -Medical News Today (press release), New Data for Zelnorm® Demonstrate Relief of Multiple Symptoms of ...  Oct 24, 2006
LAS VEGAS -- Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type dyspepsia, according to new data being ... -EndoNurse, New Data for Zelnorm Demonstrate Relief of Multiple Symptoms of ...  Oct 23, 2006
LAS VEGAS, October 23, 2006 /PRNewswire-FirstCall/ -- Zelnorm (tegaserod maleate) has demonstrated potential to treat the multiple symptoms of dysmotility-type ... -PharmaLive.com (press release), Salix Pharmaceuticals Reports American College of Gastroenterology ...  Oct 24, 2006
Patients received XIFAXAN 1200 mg per day for ten days, followed by zinc 220 mg per day and a probiotic for one month and tegaserod 3 mg per day. ... -Genetic Engineering News (press release), ACG: Chronic Constipation Linked to Higher Long-Term Mortality ...  Oct 31, 2006
...to be done, Dr. Talley said. The study was supported in part by Novartis, maker of Zelnorm (tegaserod). The drug is approved by ... -MedPage Today, Antibiotic Aims at IBS Bloating and Global Symptoms  Oct 19, 2006
Individuals taking tegaserod and antidepressants were excluded as well as those who reported taking an oral antibiotic within the previous three months. ... -MedPage Today, Millions Live with Painful GI Symptoms Impacting Their Lives, but ...  Oct 9, 2006
Novartis Pharmaceuticals Corporation, manufacturer of Zelnorm(R) (tegaserod maleate), is the exclusive sponsor of the ABCs of GI Relief Health Center at RealAge ... -Drug Newswire (press release), Mirtazapine for Severe Gastroparesis Unresponsive to Conventional ...  Sep 7, 2006
...in 7 months, to conventional prokinetics (erythromycin, metoclopramide, domperidone, perphenazine, itopride, bethanechol, and/or tegaserod) and pyloric ... -Psychosomatics (subscription)

Research and Markets: A Fourth Division for Novartis Under the ...  Sep 1, 2006
These include: Diovan (valsartan), Glivec/Gleevec (imatinib), Zelmac/Zelnorm (tegaserod), Femara (letrozole) and Zometa (zoledronate). ... -International News Service

Long-Term Tegaserod Safe, Effective Treatment for Chronic Constipation  -  Dec 8, 2006
Medscape (subscription)December 8, 2006 — Tegaserod (Zelnorm) used for up to 16 months is a safe, well tolerated, and effective treatment for patients with chronic constipation,

Suffering From Chronic Constipation?  -  Nov 27, 2006
Science Daily (press release)New research has found that a new medication, tegaserod, is effective in treating nearly all symptoms associated with chronic constipation (CC),

Suffering From Chronic Constipation?  -  Nov 22, 2006
DG NewsTegaserod is currently the only drug aside from laxatives found to be effective at treating such a wide variety of symptoms. This research is published in

New hope for millions suffering from chronic constipation  -  Nov 23, 2006
DailyIndia.com,Reporting their discovery in the American Journal of Gastroenterology, they said that Tegaserod is the only drug aside from laxatives, which is effective at

New medication for chronic constipation  -  Nov 24, 2006
United Press International24 (UPI) -- A new medication, tegaserod, is effective in treating nearly all symptoms associated with chronic constipation, according to German researchers.

Just Released: Science Closer To Fart Cure  -  Nov 27, 2006
DigitalJournal.com,The drug, named Tegaserod, also helps alleviate flatulence and bloating. The smell of a new day on the horizon has the world breathing easier.

Guthrie names chairman of Surgery Department  -  Dec 10, 2006
Elmira Star-Gazette,He was recently awarded a grant from the Guthrie Research Foundation to study and define the safety and efficacy of Zelnorm (tegaserod) use to reduce the

New medications for constipation have merit, but may be unnecessary  -  Nov 30, 2006
Savannah Morning News,Lactulose, polyethylene glycol 3350 commercially known as MiraLax, tegaserod commercially known as Zelnorm, and the new medication lubiprostone commercially

AbelsonTaylor Expands DTC Capabilities  -  Nov 27, 2006
PharmaLive.com (press release),...of the most successful Rx consumer launches in history, including the Gold Effie Award-winning campaign for Zelnorm (tegaserod maleate) from Novartis.

Interest heats up in gastrointestinal space  Jul 7, 2006
...and Drug Administration (FDA) approval for treatment of IBS are Lotronex (alosetron), developed by GlaxoSmithKline of London, and Zelnorm (tegaserod), known as ... -Nature.com (subscription)



Medical Edge: Change your eating habits for underacheiving stomach  May 13, 2006
For example, the medication tegaserod, which is already approved in the United States for treating irritable bowel syndrome and constipation, also appears to ... - Bryan College Station Eagle

Axcan Pharma appoints new Senior Vice President and Chief ...  May 10, 2006
While at Novartis, Dr. LeBeaut served as a project leader on major research programs, including the development of Zelnorm® (tegaserod maleate), a drug that ... - Yahoo! News

Making the Link  May 2, 2006
It was in this environment that Novartis took Zelnorm (tegaserod) before FDA for approval for use in constipation-predominant IBS patients. ... - PharmExec.com





Novartis provides update on regulatory status of Zelnorm? in ...  Mar 24, 2006
...received an opinion from the European Medicines Evaluation Agency’s review committee (CHMP) recommending against approval of Zelnorm? (tegaserod) in for ... - WebWire

From the analyst's couch: The GERD market  Apr 7, 2006
However, several next-generation 5-HT receptor agonists in development might have such effects (Table 1), such as tegaserod (Novartis), DDP733/pumosetrag ... - Nature.com (subscription)

Questions and Answers on Recommendation for Refusal of Marketing ...  Mar 24, 2006
Zelnorm is a tablet to be swallowed. It contains 6 mg of the active ingredient tegaserod. ... Tegaserod, the active ingredient in Zelnorm, is a receptor agonist. ... - PharmaLive.com

Novartis' IBS drug rejected by EU regulators  Mar 27, 2006
The European Medicines Agency's (EMEA) review committee has recommended against the approval of Swiss drug major Novartis' Zelnorm (tegaserod) for the ... - Therapeutics Daily (subscription)

Drugs for Irritable Bowel Syndrome  Mar 16, 2006
...by the introduction of high-priced therapies, most notably the 5-HT receptor modulators, including Novartis's Zelnorm/Zelmac (tegaserod), Alizyme's renzapride ... - EndoNurse

European Medicines Agency: Committee for Medicinal Products for ...  Mar 24, 2006
...on 15 December 2005, the Committee confirmed its previous position, recommending not to grant a marketing authorisation for Zelnorm (tegaserod), from Novartis ... - PharmaLive.com

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