Recent news on Temodar

Celldex Therapeutics Initiates A Definitive Phase 2/3 Clinical ...  -  25 May 2007
Medical News Today (press release),Celldex Therapeutics announced today that the company has initiated the ACT III study, a randomized, multi- institution Phase 2/3 clinical trial.

Companies marketing drugs for 'off-label' use  -  May 10, 2007
Miami Herald,...it lied to the government about drug prices and illegally promoted Temodar and Intron A for the treatment of certain cancers without approval.

Schering-Plough Reports Financial Results for First Quarter of 2007  -  Apr 19, 2007
PR Newswire (press release),Sales of TEMODAR, a treatment for certain types of brain tumors, grew 20 percent to $196 million due primarily to continued utilization in Europe for

Schering-Plough Sued in NJ for Marketing Drugs for Off-Label Uses  -  Apr 23, 2007
Law.com (subscription),Intron/Temodar Consumer Class Action, 06-Civ.-5774, are filed by health insurers, unions and consumers. The drugs at the center of the litigation are Intron

SP delivers again, beating forecasts  -  Apr 20, 2007
Pharma Times (subscription),Sales of Temodar (temozolomide), a treatment for certain types of brain tumours, rose 20% to $196 million as a result of continued use in Europe for

Schering-Plough Q1 Net Surges 55%; Sales Up 17% - Update  -  Apr 19, 2007
Trading Markets,International sales of prescription Claritin improved to $112 million from $101 million, while sales of Temodar grew 20% to $196 million, the company said.

Tracon Licenses D93 Antibody From Micromet  -  Mar 18, 2007
BioWorld Online,A Phase I trial in combination with Temodar (temozolomide, Schering Plough Corp.) is slated for early in the second quarter, with an investigational new

Chemo wafers helping brain cancer patients live a better life  -  Mar 3, 2007
St. Petersburg Times,In Izandick's case, he supplemented the wafers with 18 months of Temodar pills, another form of chemotherapy which he took five days out of each month.

New Hampshire : Pharmaceutical Manufacturer Schering-Plough Pays ...  -  Feb 27, 2007
All American Patriots (press release),The settlement also addressed additional allegations that the company engaged in the improper off-label marketing of Temodar, a medication used to treat

NH gest $490000 in drug company settlemnt  -  Feb 24, 2007
Boston Globe,The company was also accused of improperly marketing a brain cancer drug called Temodar as a treatment for types of cancer it wasn't approved to treat.

Genta Incorporated Announces Fourth Quarter and Year End 2006 ...  -  Feb 15, 2007
Drug Newswire (press release),...the rapid clinical translation of preclinical results that showed marked anticancer synergy when Genasense was combined with Abraxane and Temodar.

ALICIA'S STORY Goodbye, interferon, hello, chemo -- new step in ...  -  Feb 2, 2007
San Francisco Chronicle,The upshot: When the cancer cells decide to act out and replicate like over-fertile rabbits, a sizable amount of Temodar is there to stop them.

Schering-Plough Q4 Profit Increases On Higher Prescription Drug ...  -  Jan 29, 2007
Trading Markets,Net sales for the quarter increased 14%, on strong growth in sales of prescription drugs Remicade, Nasonex and Temodar, as well as higher sales from its

In settlement, Louisiana gets $7.6 million from NJ drug firm  -  Feb 9, 2007
KATC,The company was also accused of improperly marketing a brain cancer drug called Temodar as a treatment for types of cancer it wasn't approved to treat.

Temozolomide Effective for Brain Tumor Treatment: Presented at ICACT  -  Feb 8, 2007
DG NewsPARIS, FRANCE -- February 8, 2007 -- The oral alkylating agent temozolomide (Temodar) has shown favorable results in a small study of adults with

AG says Vermont received $725000 drug settlement  -  Feb 5, 2007
Legal News Line,...and K-Dur, and for partaking in illegal business practices with the drugs Temodar and Intron A. Schering-Plough was alleged to have offered kickbacks to

Schering-Plough Q4 profit up  -  Jan 29, 2007
Pharmaceutical Business ReviewSchering-Plough's leading prescription products like Remicade were up 32%, Nasonex up 28%, Peg-Intron up 11%, Temodar up 20%, and Clarinex/Aerius was up 12%

Schering-Plough Reports Financial Results for 2006 Fourth Quarter ...  -  Jan 29, 2007
PR Newswire (press release),Sales of TEMODAR, a treatment for certain types of brain tumors, grew 18 percent to $189 million due primarily to continued utilization in Europe for

Schering-Plough Fourth Quarter Earnings Call  -  Jan 30, 2007
123Jump.com,The growth rate for TEMODAR has moderated, as significant market penetration has already been achieved in the treatment of GBM. Also reporting higher sales

Q4 2006 Genta Earnings Conference Call - Final  -  Feb 20, 2007
Insurance News Net,Can you comment on -- you mentioned the Phase I trial that's ongoing right now in combination with Temodar and Abraxane. And then also, the sub-Q trial.

HealthNet offers hope to cancer patient  -  Feb 13, 2007
Connecticut Post,...or better reduction in the size of their tumors as compared to the approved drug, Temodar, which has only a 5 percent response rate," Friedman said.

Drug makers lack pill for giant profits  -  Feb 10, 2007
NorthJersey.com,Kenilworth-based Schering-Plough has about a dozen treatments in Phase III, including Remicade for pediatric Crohn's disease and Temodar for metastatic

Louisiana Settles with Schering-Plough  -  Feb 10, 2007
All American Patriots (press release),...the improper “off-label� marketing of brain cancer medication Temodar; and the company’s payment of illegal remuneration to physicians to induce them to

Bruning Announces $1.8 Million Medicaid Fraud Settlement  -  Feb 9, 2007
Southwest Nebraska News,The company also allegedly improperly marketed a medication called Temodar, which was approved by the Food and Drug Administration for the treatment of a

Maryland : Maryland Attorney General Gansler Announces $1 Million ...  -  Feb 7, 2007
All American Patriots (press release),The settlement also resolves allegations that Schering made illegal payments to physicians to induce them to use its cancer drugs Temodar and Intron A for

Vermont : Schering-Plough Pays $435 Million For Improper Marketing ...  -  Feb 6, 2007
All American Patriots (press release),The illegal marketing concerns the drugs Temodar, used in the treatment of brain tumors and metastases, and Intron A, used in the treatment of superficial

Schering-Plough profit boosted by Remicade  -  Jan 29, 2007
MarketWatchSales of brain cancer drug Temodar grew 18% to $189 million, driven stronger European sales and the product's 2006 launch in Japan.

Schering-Plough's turnaround is moving on apace  -  Jan 30, 2007
Pharma Times (subscription),Brain cancer treatment Temodar enjoyed a sales rise of 18% to $189 million, but Peg-Intron (peginterferon alfa) fell 3% to $208 million, hampered by a

Nasonex Unclogs Schering-Plough Profit  -  Jan 29, 2007
Smartmoney.comSales of Temodar, a treatment for certain types of brain tumors, grew 18% to $189 million, driven by continued utilization in Europe for treating newly

Pharma Sector: Few Newsmakers Of The Week - Exelixis, MGI Pharma ...  -  Feb 3, 2007
Trading Markets,...efficacy of Genasense when combined with Abraxis Oncology's Abraxane and Schering Plough's Temodar in patients not previously treated with chemotherapy.

Pharma Sector: Few Newsmakers Of The Week - Opexa, J&J, Glaxo ...  -  Feb 11, 2007
Trading Markets,...evaluates the safety and efficacy of Genasense when combined with Abraxis Oncology's Abraxane and Schering Plough's Temodar in patients not previously

Prescription Drugs | Schering-Plough To Pay $435M to Settle ...  -  18 Jan 2007
Kaiser network.org,DOJ alleged that Schering engaged in illegal sales and marketing programs for several cancer treatments, including the brain cancer drug Temodar and bladder

EntreMed's Panzem(R) Demonstrates Antitumor Activity In Brain ...  -  Dec 22, 2006
Medical News Today (press release),Previously, EntreMed has presented preclinical data showing that combination treatment with 2ME2 and Temodar(R) (temozolomide) resulted in a marked

An innovation in chemo  -  Jan 17, 2007
Newsday,At Stony Brook, doctors also have added an oral cancer drug called Temodar to the treatment. Dr. Keith Black, chairman of neurosurgery at Cedars-Sinai

Volunteers work together to help uninsured New Lenox man  -  Dec 21, 2006
Joliet Herald News,Jim now takes Temodar, which costs $9000 for Jim's monthly dose, to manage his seizures. That medication decision prompted more teamwork,

Safe Practice Guidelines for Oral Chemotherapy Found Gravely Lacking  -  Jan 12, 2007
MedPage Today,Cytoxan (cyclophosphamide), Iressa (gefitinib), Gleevec (imatinib), oral Rheumatrex (oral methotrexate), and Temodar (temozolomide).

Genta Initiates Pilot Clinical Trial of Genasense® Plus Abraxane ...  -  Nov 30, 2006
PipelineReview.com (press release),...particles for injectable suspension) (albumin-bound) (Abraxis BioScience, Inc.) and Temodar® (temozolomide) Capsules (Schering-Plough, Corporation).

Genta Initiates Pilot Clinical Trial of Genasense Plus Abraxane ...  -  Nov 29, 2006
PharmaLive.com (press release),...was combined with Abraxane(R) (paclitaxel protein-bound particles; Abraxis Oncology, Inc.) and Temodar(R) (temozolomide; Schering Plough, Inc.).

EntreMed's Panzem(R) Demonstrates Antitumor Activity In Brain ...  -  Dec 22, 2006
Medical News Today (press release),Previously, EntreMed has presented preclinical data showing that combination treatment with 2ME2 and Temodar(R) (temozolomide) resulted in a marked

Pharminox, Schering-Plough Enter Deal Worth Up To $40M  -  Dec 12, 2006
Therapeutics Daily (subscription) (press release),The deal is to find successor compounds to temozolomide (Temodal/Temodar), which Schering markets worldwide for malignant glioma.

Genta Initiates Pilot Clinical Trial of Genasense(R) Plus Abraxane ...  -  Nov 29, 2006
Yahoo! News (press release)Genasense was combined with Abraxane® (paclitaxel protein-bound particles; Abraxis Oncology, Inc.) and Temodar® (temozolomide; Schering Plough, Inc.).

Onyx/Bayer: to pursue development of Nexavar despite study failure  -  Dec 5, 2006
Pharmaceutical Business Review...who had progressed after one prior chemotherapy regimen containing either the standard agent dacarbazine or Schering-Plough's Temodar (temozolomide).

Volunteers work together to help uninsured New Lenox man  -  Dec 21, 2006
Joliet Herald News,Jim now takes Temodar, which costs $9000 for Jim's monthly dose, to manage his seizures. That medication decision prompted more teamwork,

Genta begins trial of Genasense  -  Nov 29, 2006
United Press InternationalThe pilot study will evaluate the three-drug combination of Genasense, Abraxis' Abraxane and Schering Plough's Temodar in chemotherapy-naive patients.

With cancer comes a lifetime of lessons  -  Dec 11, 2006
St. Petersburg Times,...the trial drug talampanel along with the standard treatment of six weeks of radiation to the brain and the chemotherapy drug temodar (temozolomide).

Pharma Sector: Few Newsmakers Of The Week - Teva, Barr, Genta ...  -  Dec 1, 2006
Trading Markets,...efficacy, pharmacokinetics and pharmacodynamics of Genasense when combined with Abraxis Oncology's Abraxane and Schering Plough's Temodar in patients

Genasense(R) Shown Active using Intermittent Dosing in Melanoma ...  09 Nov 2006
The use of Genasense plus Abraxane® (paclitaxel protein-bound particles; Abraxis Oncology, Inc.) and Temodar® (temozolomide; Schering Plough, Inc.) also ... -Yahoo! News (press release) Earnings Calls: Schering-Plough Third Quarter Earnings Call  Oct 23, 2006
...this quarter. Key products like REMICADE, NASONEX, TEMODAR, and PEG-INTRON also contributed to the growth in the quarter. While ... -123Jump.com, Addition of Genasense® to DTIC-Dome® Improves Outcomes in ...  Oct 10, 2006
Recently, Temodar® (temozolomide) has supplanted DTIC as the standard palliative treatment. A randomized trial has shown equivalent ... -Cancer Consultants (press release), Schering-Plough Reports Financial Results for 2006 Third Quarter  Oct 20, 2006
40 mg). -- Launching TEMODAL (marketed as TEMODAR in the United States) in Japan for the treatment of malignant glioma. Japanese ... -PR Newswire (press release), Schering-Plough Posts Major Increase in Net Income  Oct 20, 2006
...by growth in prescription pharmaceuticals, including higher sales of Remicade, Nasonex, Peg-Intron hepatitis C product, Clarinex, and Temodar, reports Schering ... -Genetic Engineering News (press release), Pharmacyclics Reports First Quarter Financial Results  Oct 26, 2006
...of Xcytrin plus radiosurgery for treatment of brain metastases; -- Completed patient enrollment in a Phase 1 trial of Xcytrin plus Temodar(R) (temozolomide ... -PR Newswire (press release), Strong drug sales boost Schering-Plough  Oct 20, 2006
...quarter earnings early Friday, as revenue motored up 13% over last year's quarter, powered largely by strong sales of its drugs Remicade, Temodar and Nasonex. ... -Therapeutics Daily (subscription) (press release), Foro de Shell Security - Seguridad informática  Oct 26, 2006
...cytotoxic T lympho telmisartan ytes (CTLs): CD8 and HLA-DR+, which are detectabl temazepam in both the blood and bone marrow of patients temodar with aplastic ... -Shell Security, Pharmacyclics Reports First Quarter Financial Results  Oct 26, 2006
Inc. Temodar® is a registered trademark of Schering-Plough Corp. Taxotere® is a registered trademark of Sanofi-Aventis. Alimta ... -Yahoo! News (press release) Pharmacyclics Reports First Quarter Financial Results  Oct 26, 2006
The differences in non-GAAP and GAAP numbers are reconciled in the tables below. Temodar(R) is a registered trademark of Schering-Plough Corp. ... -Earthtimes.org Schering-Plough Net Rises Fivefold on Vytorin, Zetia (Update2)  Oct 20, 2006
...arthritis treatment that Schering- Plough markets outside the US gained 34 percent to $317 million in the quarter, and sales of the Temodar brain tumor ... -Bloomberg RPT-UPDATE 4-Schering-Plough 3rd-quarter profit soars  Oct 20, 2006
...billion. Sales were bolstered by growing demand for arthritis drug Remicade, Nasonex allergy spray and brain cancer treatment Temodar. ... -Reuters.uk, The New Schering-Plough  Oct 23, 2006
Sales growth will continue because Remicade recently received an improved label in Europe for additional indications, Temodar finally was approved in Japan ... -Motley Fool Schering-Plough registers profit surge  Oct 20, 2006
The firm noted higher sales for Remicade, an arthritis treatment, Nasonex, a nasal allergy drug, and Temodar, a drug to fight certain brain tumors. ... -commercialappeal.com (subscription), Pharminox, Schering-Plough Enter Deal Worth Up To $40M  -  12 Dec 2006
Therapeutics Daily (subscription) (press release),The deal is to find successor compounds to temozolomide (Temodal/Temodar), which Schering markets worldwide for malignant glioma.

Genta Initiates Pilot Clinical Trial of Genasense Plus Abraxane ...  -  12 Dec 2006
PharmaLive.com (press release),...was combined with Abraxane(R) (paclitaxel protein-bound particles; Abraxis Oncology, Inc.) and Temodar(R) (temozolomide; Schering Plough, Inc.).

Genta Initiates Pilot Clinical Trial of Genasense® Plus Abraxane ...  -  Nov 30, 2006
PipelineReview.com (press release),...particles for injectable suspension) (albumin-bound) (Abraxis BioScience, Inc.) and Temodar® (temozolomide) Capsules (Schering-Plough, Corporation).

Onyx/Bayer: to pursue development of Nexavar despite study failure  -  Dec 5, 2006
Pharmaceutical Business Review...who had progressed after one prior chemotherapy regimen containing either the standard agent dacarbazine or Schering-Plough's Temodar (temozolomide).

Genta Initiates Pilot Clinical Trial of Genasense(R) Plus Abraxane ...  -  Nov 29, 2006
Yahoo! News (press release)Genasense was combined with Abraxane® (paclitaxel protein-bound particles; Abraxis Oncology, Inc.) and Temodar® (temozolomide; Schering Plough, Inc.).

With cancer comes a lifetime of lessons  -  Dec 11, 2006
St. Petersburg Times,...the trial drug talampanel along with the standard treatment of six weeks of radiation to the brain and the chemotherapy drug temodar (temozolomide).

Genta begins trial of Genasense  -  Nov 29, 2006
United Press InternationalThe pilot study will evaluate the three-drug combination of Genasense, Abraxis' Abraxane and Schering Plough's Temodar in chemotherapy-naive patients.

Pharma Sector: Few Newsmakers Of The Week - Teva, Barr, Genta ...  -  Dec 1, 2006
Trading Markets,...efficacy, pharmacokinetics and pharmacodynamics of Genasense when combined with Abraxis Oncology's Abraxane and Schering Plough's Temodar in patients



Temodar® and Thalomid® Effective for Advanced Neuroendocrine ...  Mar 20, 2006
According to an article recently published in the Journal of Clinical Oncology, the treatment combination consisting of Temodar® (temozolomide) and Thalomid ... - Cancer Consultants

Temodar® and Thalomid® Effective for Metastatic Neuroendocrine ...  Mar 21, 2006
Researchers from the Dana-Farber Cancer Center have reported that the oral administration of Temodar (temozolomide) and Thalomid (thalidomide) in patients with ... - Cancer Consultants

EntreMed Presents Preclinical Results at AACR for Panzem and ENMD ...  Apr 3, 2006
In one preclinical study, daily oral administration of 2ME2 in combination with a maximally tolerated course of Temodar(R) (temozolomide) resulted in 87 ... - PharmaLive.com

Schering-Plough debt rating outlook raised to stable - S&P  Mar 24, 2006
However, the company does not have any major patent expirations over the next several years, with cancer product Temodar in 2011 being the earliest. ... - Forbes



Patients With Newly Diagnosed Glioblastoma Multiforme - Health ...  Feb 6, 2006
Schering-Plough markets temozolomide in the United States as TEMODAR(R) Capsules. ... Patients treated with TEMODAR Capsules may experience myelosuppression. ... - Medical News Today,

Health Canada Approves TEMODAL(R)(temozolomide) for Patients With ...  Feb 2, 2006
Schering-Plough markets temozolomide in the United States as TEMODAR(R) Capsules. Schering-Plough received accelerated approval ... - PR Newswire,

Canada OKs Schering-Plough cancer drug  Feb 2, 2006
The drug, known generically as temozolomide and sold in the United States as Temodar, was approved for patients with glioblastoma multiforme, a form of ... - BusinessWeek

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