Recent news on Thioguanine

Toxicogenomics for Compound Selection  -  May 15, 2007
Genetic Engineering News (press release),These associations were not observed for any of the other compound treatments analyzed in this study, with the exception of one high-dose thioguanine

Long wavelength Krystal-UV plates for Biomedical screening assays  -  Apr 18, 2007
MeasurementDevices,Wavelengths below 350nm are particularly useful for a variety of fluorescence assays such as HNK-1 (Fluorescence EM 325nm, EX 380nm), Thioguanine (EX 330nm,

Intravenous Oncaspar® Safe and Effective in Children with ALL  -  Jan 5, 2007
Cancer Consultants (press release),Another study presented at ASH 2006 showed that sequencing Oncaspar after cytarabine plus thioguanine may help in overcoming cell resistance to cytarabine

No Advantage Found for 6-Thioguanine in Childhood ALL  Oct 13, 2006
13 -- Children with acute lymphoblastic leukemia (ALL) had half the isolated CNS relapse rate when treated with 6-thioguanine versus 6-mercaptopurine, but the ... -MedPage Today, Mercaptopurine Confirmed Preferable to Thioguanine for Childhood ...  Oct 17, 2006
Researchers affiliated with the UK Medical Research Council’s ALL97 trial have reported that maintenance 6-thioguanine (6-TG) causes excess toxicity and no ... -Cancer Consultants (press release), 6-mercaptopurine Remains Standard Agent for Acute Lymphoblastic ...  Oct 16, 2006
6-thioguanine is another thiopurine that ultimately produces the same anticancer activity as 6-mercaptopurine. However, the agents are metabolized differently. ... -Cancer Consultants (press release), Advances in the Use of Nonbiologic Agents to Treat Inflammatory ...  Jun 22, 2006
6-thioguanine nucleotides (6-TGN) are known to be the active metabolites of both AZA* and 6-mercaptopurine (6-MP).* The principal metabolites of 6-TGN are 6 ... -Medscape (subscription)

Personalised Medicine: A Revolution In Healthcare  Jan 18, 2006
In cancer chemotherapy of acute lymphocytic leukemia, administration of drugs such as 6-mercaptopurine , 6-thioguanine, and azathioprine can cause severe ... - Express Healthcare Management

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