Recent news on Thrombolytic

Committee for Medicinal Products for Human Use Post-Authorisation ...  -  25 May 2007
PharmaLive.com (press release),ST segment elevation acute myocardial infarction, in combination with ASA in medically treated patients eligible for thrombolytic therapy.

EU drug panel doesn't back Amgen's Vectibix for colon cancer  -  25 May 2007
MarketWatch...myocardial infarction) and of patients suffering from ST segment elevation acute myocardial infarction who are eligible for thrombolytic therapy.

DVT: New Therapeutic Perspectives Part II  -  May 17, 2007
Therapeutics Daily (subscription) (press release),...stockings and early ambulation are discussed. Adjunctive therapy with veno-caval filters and catheter-directed thrombolytic therapy is reviewed

Nuvelo Announces Upcoming Conference Calls, Webcasts and ...  -  May 24, 2007
PR Newswire (press release),Nuvelo's development pipeline includes three acute cardiovascular programs: alfimeprase, a direct-acting thrombolytic for the treatment of

Stroke Rates Vary Widely in US, Treatment Often Delayed  -  May 17, 2007
Medscape (subscription)Findings from the second study indicate that stroke patients usually do not arrive within 2 hours of stroke onset, making it difficult for thrombolytic

Microbix Announces Second Quarter Results and Provides Update on ...  -  May 15, 2007
CNW Telbec (Communiqués de presse),Interest has been propelled by the clinical proof of concept as Urokinase has been used in patients as a thrombolytic drug.

Actilyse(R) (alteplase) recommended by National Institute for ...  -  May 14, 2007
PipelineReview.com (press release),...safety of intravenous thrombolysis using Actilyse(R) in patients with acute ischaemic stroke and confirm that the thrombolytic therapy with Actilyse(R)

Actilyse (alteplase) Recommended by National Institute for Health ...  -  May 14, 2007
PharmaLive.com (press release),...efficacy and safety of intravenous thrombolysis using Actilyse® in patients with acute ischaemic stroke and confirm that the thrombolytic therapy with

Biolex Therapeutics Announces Agreement With Genmab for New Class ...  -  May 10, 2007
Carolina Newswire (press release),The Company's second product candidate, BLX-155, is a direct-acting thrombolytic, designed to break up clots in certain diseases such as acute peripheral

Guidelines Updated for Treatment of Spontaneous Intracerebral ...  -  May 3, 2007
Medscape (subscription)Treatment of patients with ICH caused by thrombolytic therapy includes urgent empirical therapies to replace clotting factors and platelets (IIb, B).

Biolex Therapeutics Announces Strategic Collaboration With Merial ...  -  May 1, 2007
SYS-CON Media,BLX-155, is a direct-acting thrombolytic, designed to break up clots in certain diseases such as acute peripheral arterial disease, deep vein thrombosis

AngioDynamics Expands PTA Balloon Dilatation Catheter Portfolio ...  -  May 1, 2007
American Digital Networks (press release),...drainage products, thrombolytic products, embolization products and venous products. More information is available at www.angiodynamics.com.

AAN: Advice by Phone Speeds Thrombolysis for Ischemic Stroke  -  Apr 25, 2007
MedPage Today,...patients having an acute ischemic stroke were able to deliver thrombolytic therapy within the three-hour therapeutic window, reported Anand G. Vaishnav,

Microbix Provides Update on Urokinase Project Financing  -  Apr 5, 2007
Drug Newswire (press release),As a thrombolytic, or 'clot-busting' drug, Urokinase has benefited more than five million patients and has had an excellent safety and patient-tolerance

Compare How Heart Failure & Pneumonia is Treated in Hospitals ...  -  Apr 25, 2007
Business Wire (press release),Inhibitor for LVSD, Beta Blocker at Arrival, Beta Blocker at Discharge, Thrombolytic Agent Received, PTCA Received and Adult Smoking Cessation Advice.

Percutaneous Coronary Intervention vs Thrombolysis for ST ...  -  Mar 27, 2007
Journal of American Medical Association (subscription),In the Danish Multicenter Randomized Study on Thrombolytic Therapy vs Acute Coronary Angioplasty in Acute Myocardial Infarction 2 (DANAMI-2) trial,

AAN: Advice by Phone Speeds Thrombolysis for Ischemic Stroke  -  Apr 25, 2007
MedPage Today,...patients having an acute ischemic stroke were able to deliver thrombolytic therapy within the three-hour therapeutic window, reported Anand G. Vaishnav,

Nuvelo Announces Upcoming Conference Calls, Webcasts and ...  -  Apr 25, 2007
PharmaLive.com (press release),Nuvelo's development pipeline includes three acute cardiovascular programs: alfimeprase, a direct-acting thrombolytic for the treatment of

Microbix Provides Update on Urokinase Project Financing  -  Mar 28, 2007
PR-Inside.com (Pressemitteilung),..."The market potential for a new specific Urokinase-based thrombolytic drug is in excess of $100 million annually. At the same time, the development risk is

Talecris Biotherapeutics Picks Diosynth To Make Materials  -  Apr 3, 2007
WRAL.com,Diosynth will manufacture recombinant plasminogen (found in body fluids and plasma), which Talecris is developing for use in ophthalmic and thrombolytic

Information on hospitals available online for free  -  Mar 30, 2007
Honolulu Advertiser,...initial antibiotics within four hours after arrival or percentage of heart attack patients given thrombolytic medication within 30 minutes of arrival.

A heavy heart  -  Apr 24, 2007
Newindpress (subscription),This problem should be addressed immediately by redoing an open-heart surgery or IV thrombolytic therapy. Otherwise majority of the patients will die early.

Gentium's Defibrotide Highlighted in Poster Presentation at World ...  -  Apr 23, 2007
PharmaLive.com (press release),It has previously been reported that Defibrotide, a polydisperse oligonucleotide with anti-thrombotic, thrombolytic, anti-ischemic and anti-angiogenic

Lowering Blood Pressure Following Stroke May Reduce Damage  -  Apr 23, 2007
Medical News Today (press release),After three hours, the suture was removed to simulate the effect of thrombolytic, or clot-busting, drugs. The rats were then given one of two common blood

Heart attacks are worse on Sunday  -  Mar 31, 2007
Daily News & Analysis,There are three lines of aggressive treatment -- thrombolytic therapy, angioplasty and bypass surgery. “A delay of an hour or half-an-hour could be fatal,�

Medicure's Aggrastatr Highlighted in Expert Opinion Journal  -  Apr 20, 2007
PharmaLive.com (press release),The safety of AGGRASTATR when used in combination with thrombolytic agents has not been established. During therapy with AGGRASTATR, patients should be

Percutaneous Coronary Intervention vs Thrombolysis for ST ...  -  Mar 27, 2007
Journal of American Medical Association (subscription),Thus, we currently see few reasons to use an expensive thrombolytic therapy, with the inherent risk of bleeding complications when combined with rescue PCI,

New Guidelines for Treatment of Acute Ischemic Stroke  -  Apr 19, 2007
Medscape (subscription)Treatment with streptokinase is not recommended, and reteplase, urokinase, and other thrombolytic agents should not be used outside of the setting of a

Lowering blood pressure following stroke may reduce damage  -  Apr 18, 2007
SpiritIndia,After three hours, the suture was removed to simulate the effect of thrombolytic, or clot-busting, drugs. The rats were then given one of two common blood

AngioDynamics Reports Strong Fiscal Third Quarter Results  -  Mar 28, 2007
PharmaLive.com (press release),Interventional product sales, which include the Company's Angiographic, Thrombolytic, Dialysis, IGVA, PTA, Venous and Drainage product lines, totaled $24.5

Thrombogenics Announces License Agreement With Millipore for ...  -  Apr 16, 2007
PR Newswire (press release),...which is being evaluated as a treatment for vitreoretinal disorders and as a thrombolytic agent for vascular occlusive diseases, including acute stroke.

Nuvelo Announces Publication of NU206 Study Results in ...  -  Apr 13, 2007
Drug Newswire (press release),Nuvelo's development pipeline includes three acute cardiovascular programs: alfimeprase, a direct-acting thrombolytic for the treatment of

Primary Percutaneous Coronary Intervention  -  Apr 11, 2007
New England Journal of Medicine (subscription),Inciting events, including vascular surgery, arteriography, angioplasty, anticoagulation with heparin, and thrombolytic therapy, can be identified in 50% of

Exploring Therapies for Acute Coronary Syndromes: IIb/IIIa ...  -  Apr 10, 2007
TheHeart.Org,The standard of care for patients with ACS is a polypharmacologic approach consisting of the early administration of thrombolytic agents, aspirin,

Telemedicine brings high-end stroke care to area hospitals  -  Apr 8, 2007
Evening Observer,The system will allow for treatments such as “clot-busting� medications like tPa (thrombolytic tissue type plasminogen activator), which were only available

3.6 Million Black Women Play Russian Roulette With Cigarettes  -  Apr 8, 2007
Louisiana Weekly,..."Most of the 1 million US patients who suffer a heart attack each year are candidates for reperfusion therapy, either thrombolytic (clot-busting) drugs or

Serial Changes in CT Cerebral Blood Volume and Flow after 4 Hours ...  -  Apr 6, 2007
AJNR (subscription),BACKGROUND AND PURPOSE: Neuroimaging techniques have the potential to improve acute stroke treatment by selecting the appropriate patients for thrombolytic

Contract manufacturing news in brief  -  Apr 3, 2007
In-PharmaTechnologist.com,...material used in the manufacture of recombinant Plasmin, a second-generation therapy Talecris is developing as an ophthalmic and thrombolytic treatment.

Diosynth Biotechnology Announces Agreement with Talecris ...  -  Apr 2, 2007
PipelineReview.com (press release),...used in the manufacture of recombinant Plasmin, a second-generation therapy Talecris is developing for both ophthalmic and thrombolytic indications.

AngioDynamics Announces Plan to Launch NeverTouch(TM) VenaCure(R ...  -  Apr 2, 2007
American Digital Networks (press release),...drainage products, thrombolytic products, embolization products and venous products. More information is available at www.angiodynamics.com.

Laws, Guidelines and professional choice  -  Mar 28, 2007
European Journal of Cardio-Thoracic Surgery (subscription)Antithrombotic therapy in valvular heart disease–native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

In the Emergency Room  -  Mar 28, 2007
Emporia Gazette (subscription),Thrombolytic Medication (�clot buster�): “Clot busters� dissolve clots that can be blocking blood flow and damaging the heart.

AngioDynamics Names D. Joseph Gersuk Chief Financial Officer  -  Mar 28, 2007
Business Wire (press release),...vascular access products, angiographic products and accessories, dialysis products, angioplasty products, drainage products, thrombolytic products,

Percutaneous Coronary Intervention vs Thrombolysis for ST ...  -  Mar 27, 2007
Journal of American Medical Association (subscription),Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction. N Engl J Med. 2005;353:2758-2768. FREE FULL TEXT

Percutaneous Coronary Intervention vs Thrombolysis for ST ...  -  Mar 27, 2007
Journal of American Medical Association (subscription),PCI compared with thrombolytic therapy was independently associated with lower short-term and long-term mortality rates in patients with STEMI.

Nuvelo Receives FDA Fast Track Status for rNAPc2 in Both First ...  -  27 Mar 2007
PR Newswire (press release),Nuvelo's development pipeline includes three acute cardiovascular programs: alfimeprase, a direct-acting thrombolytic for the treatment of

GO Capital Becomes Major Shareholder in ThromboGenics  -  27 Mar 2007
PR Newswire (press release),...which is being evaluated as a treatment for vitreoretinal disorders and as a thrombolytic agent for vascular occlusive diseases, including acute stroke.

Philips Speeds Care and Improves the Patient Experience Throughout ...  -  27 Mar 2007
Genetic Engineering News (press release),...and if needed, prepare for lifesaving treatment such as Percutaneous Coronary Intervention (PCI) performed in the cath lab, or thrombolytic therapy.

Thrombolytic therapy in acute myocardial infarction: Experience at ...  -  Mar 9, 2007
HeartZine,Background: There is conclusive evidence from large clinical trials that thrombolytic therapy reduces mortality and morbidity in acute myocardial infarction

Biolex Therapeutics Researchers Present Preclinical Data for ...  -  Mar 2, 2007
PipelineReview.com (press release),BLX-155, a full-length recombinant plasmin, is a direct-acting thrombolytic agent designed to dissolve blood clots in patients with acute peripheral

Report highlights how far biotech has advanced healthcare  -  Mar 16, 2007
Cordis News,Before biotechnologists developed thrombolytic agents, cardiovascular incidences linked to clots were treated with anticoagulant agents.

SIR: 'Rapid Lysis' Dissolves Severe DVT  -  Mar 5, 2007
MedPage Today,SEATTLE, March 5 -- Combining thrombolytic medication with a clot removal device dissolves extensive deep vein thrombosis in a single session, according to

AngioDynamics to Present at Raymond James 28th Annual ...  -  Feb 27, 2007
Business Wire (press release),...drainage products, thrombolytic products, embolization products and venous products. More information is available at www.angiodynamics.com.

Herb Scene: Angelica  -  Feb 26, 2007
Jackson Clarion Ledger,Angelica can adversely interact with anticoagulants, low molecular weight heparins and thrombolytic agents. In all cases, patients should be monitored for

Talecris Initiates Clinical Development Program Evaluating Plasmin ...  -  Mar 21, 2007
PipelineReview.com (press release),Plasmin is a locally acting fibrin-binding thrombolytic derived from human plasma that can be infused directly into a clot via a catheter using minimally

Out-of-Hospital STEMI Alert  -  Mar 12, 2007
EMS Magazine,Alternatively, transport to facilities that can deliver thrombolytic therapy is acceptable if air transport to a cath lab is unavailable or impractical.

PRESIDENT’S ADDRESS AT THE XXVIII ANNUAL CONVOCATION OF PGIMER  -  Mar 7, 2007
Press Information Bureau (press release),Thrombolytic drugs like Streptokinase have reduced ICCU mortality of acute heart attacks from 15% to 5%. Appropriate and early timely use of these drugs is

Ultrasound Accelerated Thrombolysis May Decrease ICU Stay ...  -  Mar 5, 2007
DG NewsThat faster action also appears to reduce complications, such as major bleeding, that are associated with use of thrombolytic drugs.

Nuvelo Announces Presentation on rNAPc2 at American College of ...  -  Mar 19, 2007
PharmaLive.com (press release),Nuvelo's development pipeline includes three acute cardiovascular programs: alfimeprase, a direct-acting thrombolytic for the treatment of

Protein S Deficiency and Lower-Extremity Arterial Thrombosis  -  Mar 16, 2007
Journal of the American Podiatric Medical Association (subscription)Once the diagnosis of protein S deficiency was made, this patient’s treatment course included a heparin anticoagulation protocol, thrombolytic therapy and

Health briefs  -  Mar 13, 2007
Providence Journal,Williams, of Barrington, a clinician and investigator, was among the first in the country to perform coronary angioplasty and administer thrombolytic

Telemedicine can save lives, especially in underserved areas  -  Mar 13, 2007
Indianapolis Star,The stoke specialist can help determine if it is appropriate to administer a thrombolytic or clot-buster drug that can relieve the clot and drastically

STEMI Destinations; Airway Types and CPR; Child Maltreatment  -  Mar 12, 2007
EMS Magazine,Thrombolytic therapy was prescribed to 80.4% of the control group, with a median door-to-needle time of 41 minutes. In-hospital mortality was 1.9% in the

Magnetic Resonance Imaging in Ischemic Stroke  -  Mar 12, 2007
AJNR (subscription),...message that "physiology is brain" should replace "time is brain" as the mantra for thrombolytic treatment beyond currently accepted time windows.

Blood clots vacuumed up  -  Mar 5, 2007
Health24.com,In such instances, clots can be dissolved by means of a thrombolytic drug delivered by catheter. This approach is not without its drawbacks, however.

Vacuum Method Breaks Up DVT Blood Clots  -  Mar 2, 2007
drkoop.com...large clots provoking severe symptoms may not. In such instances, clots can be dissolved by means of a thrombolytic drug delivered by catheter.

Electrocardiogram in Women with Chest Pain  -  Feb 28, 2007
AEM (subscription)Presentation, delay, and contraindication to thrombolytic treatment in females and males with myocardial infarction Womens Health Issues 2003;13:214-221.

AngioDynamics Expands Vascular Access Port Portfolio with ...  -  Feb 28, 2007
Business Wire (press release),...drainage products, thrombolytic products, embolization products and venous products. More information is available at www.angiodynamics.com.

Female gender increases the risk of death during hospitalization ...  -  Mar 9, 2007
The Journal of Thoracic and Cardiovascular SurgeryDifferences in medical care include less likelihood of receiving thrombolytic therapy and cardiac catheterization, frequent gender-based referral bias for

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