Recent news on Thyrotropin

Another study links hyperthyroidism with AF  -  May 22, 2007
TheHeart.Org,The main outcome measures included tests of thyroid function (serum free thyroxine [T4] and thyrotropin [TSH]) and the presence of AF on resting

Genzyme Reports Significant Revenue and Earnings Growth in First ...  -  Apr 25, 2007
WebWire (press release),Also within the Therapeutics area, sales of Thyrogen® (thyrotropin alfa for injection) grew 15 percent to $26.3 million compared with $23.0 million in the

Levothyroxine in Euthyroid Autoimmune Thyroiditis and Type 1 ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,Serum thyrotropin, free T 4 , TPOAb, and TgAb levels were not significantly different in both groups during the entire study period.

Genzyme Reports Significant Revenue and Earnings Growth in First ...  -  26 Apr 2007
WebWire (press release),Also within the Therapeutics area, sales of Thyrogen® (thyrotropin alfa for injection) grew 15 percent to $26.3 million compared with $23.0 million in the

Recombinant Thyrotropin in the Diagnosis of Congenital Hypothyroidism  -  Apr 4, 2007
Journal of Clinical Endocrinology and Metabolism,Address all correspondence and requests for reprints to: Dov Tiosano, Meyer Children’s Hospital, POB 6092, Haifa 31096, Israel.

Hypothalamic–pituitary–adrenal axis response in borderline ...  -  Mar 30, 2007
British Journal of Psychiatry (subscription),Sternbach, HA, Fleming, J., Extein, I., et al (1983) The dexamethasone suppression and thyrotropin-releasing-hormone tests in depressed borderline patients.

Ask Dr. Debbie  -  Mar 12, 2007
Anderson Independent Mail (subscription),The hypothalamus sends a signal to the pituitary gland through a hormone called the thyrotropin-releasing hormone (TRH). When the pituitary gland is

Voluntarism in Consultation Psychiatry: The Forgotten Capacity  -  Feb 28, 2007
Am J Psychiatry (subscription)Mr. B’s thyroid laboratory test results on admission were equally impressive, with his thyrotropin level undetectable and his T 4 level at 23.4 µg/dl.

Single-Dose Rexinoid Rapidly and Specifically Suppresses Serum ...  -  Jan 5, 2007
Journal of Clinical Endocrinology and Metabolism,Wendy M. Golden, Katie B. Weber, Teri L. Hernandez, Steven I. Sherman, Whitney W. Woodmansee and Bryan R. Haugen. Address all correspondence and requests

Thyroid hormone and Na + -K + -ATPase: more than simple transcription  -  Jan 10, 2007
AJP-Lung Physiology (subscription)Australian collaborative trial of antenatal thyrotropin-releasing hormone (ACTOBAT) for prevention of neonatal respiratory disease. Lancet 345: 877–882,

Lower Colorado River basin crops fare well in perchlorate testing  -  Jan 11, 2007
Western Farm PressThe report indicated a relationship between perchlorate concentrations and the thyroid-stimulating hormone (TSH) thyrotropin. According to the report,

Thyroid Disease  -  Dec 1, 2006
About - News & Issues,The thyroid is part of a huge feedback process. The hypothalamus in the brain releases something called Thyrotropin-releasing Hormone (TRH). ...

Induction of Pulsatile Secretion of Leptin in Horses Following ...  -  Dec 13, 2006
Journal of EndocrinologyConcentrations of T 3 and T 4 were undetectable post-THX. Plasma concentrations of thyrotropin were greater post-THX vs pre-THX (P<0.001). ...

Central Hyperdopaminergism in Peduncular Hallucinosis  -  Nov 29, 2006
Journal of Neuropsychiatry (subscription)Visual imaginery lasted for 7 days. His serum thyrotropin, T4, cortisol, corticotrophin, and gonadal hormones were normal in the acute phase of stroke. ...

The Relation of Thyroid Function and Ventricular Repolarization ...  -  Dec 5, 2006
Journal of Clinical Endocrinology and Metabolism,Marcus Dörr, Jörg Ruppert, Daniel M. Robinson, Jan A. Kors, Stephan B. Felix and Henry Völzke. Address all correspondence and ...

Lung Dosimetry for Radioiodine Treatment Planning in the Case of ...  -  Nov 30, 2006
Journal of Nuclear Medicine (subscription)Reassessment of this toxicity limit is also appropriate in light of the contemporary use of recombinant thyrotropin (thyroid-stimulating hormone) (rTSH) to ...

Efficacy of oral iodized peanut oil is greater than that of ...  09 Nov 2006
The concentration of urinary iodine (UI) was measured at 0, 4, 12, 25, and 50 wk, whereas thyroid volume and serum thyrotropin and free thyroxine ... -Am J Clin Nutr (subscription), Recombinant Human Thyrotropin Reduces Endothelium-Dependent ...  Oct 27, 2006
Address all correspondence and requests for reprints to: Fabio Monzani, MD, Department of Internal Medicine, University of Pisa, via Roma 67, 56126 Pisa, Italy ... -Journal of Clinical Endocrinology and Metabolism, Hypothyroidism Linked to Better Survival in Head and Neck Cancer  Nov 2, 2006
In total 55 of the patients developed hypothyroidism, as indicated by a thyrotropin level greater than 5.5 mIU/L. Despite treatment for hypothyroidism, these ... -Cancerpage.com, Genzyme Reports Strong Third-Quarter Financial Results  Oct 12, 2006
Sales of Thyrogen® (thyrotropin alfa for injection) rose to $22.4 million in the second quarter, a 21 percent increase from sales of $18.5 million during the ... -Yahoo! News (press release) Genzyme Reports Strong Third-Quarter Financial Results  Oct 12, 2006
Sales of Thyrogen(R) (thyrotropin alfa for injection) rose to $22.4 million in the second quarter, a 21 percent increase from sales of $18.5 million during the ... -Drug Newswire (press release), Peptide YY (PYY) 3-36 modulates thyrotropin secretion in rats  Sep 15, 2006
Here we examined PYY 3-36 effects on thyrotropin (TSH) secretion, both in vitro and in vivo. PYY 3-36 -incubated rat pituitary glands ... -Journal of Endocrinology

Thyrotropin Receptor Autoantibodies Are Independent Risk Factors ...  Sep 7, 2006
Anja K. Eckstein, Marco Plicht, Hildegard Lax, Markus Neuhäuser, Klaus Mann, Sebastian Lederbogen, Christian Heckmann, Joachim Esser and Nils G. Morgenthaler. ... -Journal of Clinical Endocrinology and Metabolism

Weight Loss Sabotage  Sep 13, 2006
The hypothalamus is located above the pituitary gland in the brain. This hormone produces thyrotropin releasing hormone (TRH). The ... -Market-Day.net

September 2006 Clinical Briefs  Aug 29, 2006
The researchers looked at thyrotropin-releasing hormone, or TRH, a hormone released in the brain that kicks off a chain of events throughout the body ... -U.S. Medicine

Myasthenia Gravis Disclosed by Lithium Carbonate  Sep 8, 2006
Thyrotropin, free and total T4 and triidothyronine were in normal range. Antibodies against Acetylcholine-receptors (AchR) were high, at 45 nmol/liter. ... -Journal of Neuropsychiatry (subscription)

The Relation of Thyroid Function and Ventricular Repolarization ...  -  Dec 1, 2006
Journal of Clinical Endocrinology and Metabolism,Marcus Dörr, Jörg Ruppert, Daniel M. Robinson, Jan A. Kors, Stephan B. Felix and Henry Völzke. Address all correspondence and requests for reprints to:

Thyroid Disease  -  Dec 1, 2006
About - News & Issues,The hypothalamus in the brain releases something called Thyrotropin-releasing Hormone (TRH). The release of TRH tells the pituitary gland to release

Central Hyperdopaminergism in Peduncular Hallucinosis  -  Dec 7, 2006
Journal of Neuropsychiatry (subscription)His serum thyrotropin, T4, cortisol, corticotrophin, and gonadal hormones were normal in the acute phase of stroke. A normal prolactin and thyrotropin

Lung Dosimetry for Radioiodine Treatment Planning in the Case of ...  -  Nov 30, 2006
Journal of Nuclear Medicine (subscription)Reassessment of this toxicity limit is also appropriate in light of the contemporary use of recombinant thyrotropin (thyroid-stimulating hormone) (rTSH) to

FDA safety labeling changes for carvedilol, amiodarone  -  Nov 16, 2006
TheHeart.Org,In equivocal cases, a flat TSH response to thyrotropin-releasing hormone may be used as a confirmatory test. Because of the risk for arrhythmia

Study Suggests Anesthetic Agent May Have Rapid Antidepressant ...  Aug 18, 2006
..."To our knowledge, there has never been a report of any other drug or somatic treatment (ie, sleep deprivation, thyrotropin-releasing hormone, antidepressant ... -DG News

Radiation Exposure and Thyroid Cancer—Reply  Aug 1, 2006
...associated with iodine supplements decreased the level of thyroid stimulation (and subsequent cancer risk) by indirect inhibition of thyrotropin secretion. ... -Journal of American Medical Association (subscription)

Thyrotropin Alfa Provides Equal or Improved Quality of Life to ...  Jun 29, 2006
BOSTON, MA -- June 29, 2006 -- Patients with chemotherapy-induced anemia demonstrated that recombinant human thyrotropin (rhTSH) -- also known as thyrotropin ... -DG News

Smoking Directly Related to Thyrotropin Concentrations in Women ...  Jun 30, 2006
...[Presentation title: Dose-Response Relationship Between Smoking and Thyrotropin (TSH) Concentration in a Population-Based Survey of Brazilian Women. ... -DG News

Delivers Solid Earnings Growth Based on Strong Top-Line ...  Jul 18, 2006
Sales of Thyrogen® (thyrotropin alfa for injection) rose to $23.7 million in the second quarter, a 15 percent increase from sales of $20.7 million during the ... -Oxfordshire Bioscience Network

Effect of Iodine Intake on Thyroid Diseases  Jun 28, 2006
Among subjects with euthyroidism and antithyroid antibodies at baseline, the five-year incidence of elevated serum thyrotropin levels was greater among those ... -New England Journal of Medicine (subscription)

Genzyme Reports Second-Quarter Financial Results  Jul 12, 2006
Sales of Thyrogen(R) (thyrotropin alfa for injection) rose to $23.7 million in the second quarter, a 15 percent increase from sales of $20.7 million during the ... -Drug Newswire

Endocrinology & Metabolism News June 2006  Jun 26, 2006
The dose of thyroxine needed to achieve a low level of thyrotropin (0.05–0.20 mU/liter) in 248 patients with multinodular goiter was higher in patients with ... -Journal of Clinical Endocrinology and Metabolism



Low affinity analogs of thyrotropin-releasing hormone are super ...  16 May 2006
The researchers looked at thyrotropin-releasing hormone, or TRH, a hormone released in the brain that kicks off a chain of events throughout the body ... - News-Medical.net

A generalised fit more beneficial to drug design  16 May 2006
They started by inspecting the thyrotropin-releasing hormone (TRH), which is released in the brain that stimulates thyroid gland activity. ... - In-PharmaTechnologist.com

Thyroxine in Goiter, Helicobacter pylori Infection, and Chronic ...  Apr 26, 2006
Methods We assessed the dose of thyroxine required to obtain a low level of thyrotropin (0.05 to 0.20 mU per liter) in 248 patients with multinodular goiter. ... - New England Journal of Medicine (subscription)

Goiter-Gastritis Duo Needs Stepped-Up Thyroxine Doses  Apr 27, 2006
From 1999 to 2004, the dose of thyroxine required to achieve low levels of thyrotropin, a marker for treatment efficacy, was assessed in these patients and ... - MedPage Today

Stress and the colon: central-vagal or direct peripheral effect of ...  May 8, 2006
...can also induce gastric relaxation by inhibiting gastroexcitatory vagal efferent responses to excitatory TRHergic inputs and to thyrotropin-releasing hormone ... - AJP-Regul Integr Comp Physiology (subscription)

Genzyme Reports Financial Results for the First Quarter of 2006  Apr 19, 2006
Sales of Thyrogen(R) (thyrotropin alfa for injection) increased 30 percent to $23 million in the first quarter, up from $17.7 million a year earlier. ... - MSN Money





Sleep disruption is related to allelic variation in the ob gene  Mar 14, 2006
PD, and Van Cauter E. Leptin levels are dependent on sleep duration: relationship with sympathovagal balance, carbohydrate regulation, cortisol, and thyrotropin ... - AJP-Regul Integr Comp Physiology (subscription)



(Requests for offprints should be addressed to B De Groef ...  Feb 13, 2006
We used a real-time PCR setup to quantify whole-pituitary mRNA expression of the b subunit of thyrotropin (TSH-b), type 1 thyrotropin-releasing hormone ... - Journal of Endocrinology

Genzyme Granted Label Change for Thyrogen  Feb 1, 2006
...(Nasdaq: GENZ - News) today announced that the US Food and Drug Administration (FDA) has authorized a label modification for Thyrogen® (thyrotropin alfa for ... - Yahoo! News

Adds Improved Outcomes Data Demonstrating Patient Benefit  Feb 2, 2006
...(Nasdaq:GENZ) today announced that the US Food and Drug Administration (FDA) has authorized a label modification for Thyrogen® (thyrotropin alfa for injection ... - Oxfordshire Bioscience Network

Genzyme Granted Label Change for Thyrogen  Feb 1, 2006
...today announced that the US Food and Drug Administration (FDA) has authorized a label modification for Thyrogen(R) (thyrotropin alfa for injection) to reflect ... - International News Service

Genzyme Reports 22 Percent Increase in Fourth-Quarter Revenue  Jan 9, 2006
Sales of Thyrogen(R) (thyrotropin alfa for injection) increased 18 percent to $21 million in the fourth quarter from $18 million in the same period a year ... - MSN Money

Glycoprotein hormone receptors  Jan 17, 2006
Combination of site-directed mutagenesis and molecular dynamics simulations applied to the thyrotropin receptor (TSHr) have allowed identification of the ... - innovations report

Major Guidelines for Managing Thyroid Cancer Published in Thyroid ...  Jan 20, 2006
...extent of surgery needed for small thyroid cancers, the appropriate use of thyroxine suppression therapy, the role of recombinant human thyrotropin, and the ... - Business Wire

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