Recent news on Topiramate

VIVUS Revives Investor Interest  -  Apr 30, 2007
Motley FoolQnexa is a combination of already-approved drugs topiramate (better known as its brand Topamax) and phentermine. The company is expected to initiate a

New Medication Strategies for Comorbid Substance Use and Bipolar ...  -  May 18, 2007
Focus (subscription)Topiramate is particularly promising for alcoholism. In a recent double-blind, randomized, placebo-controlled, 12-week trial in 150 alcoholics,

Preclinical Development and Clinical Implementation of Treatments ...  -  May 18, 2007
Focus (subscription)Other receptor modulators showing some positive data include topiramate (58) and ondansetron (59), although these have not yet been approved by the FDA.

An Evidence-Based Algorithm for the Treatment of Neuropathic Pain  -  May 16, 2007
Medscape (subscription)Thienel U, Neto W, Vijapurkar U, Schwabe S. Topiramate in painful diabetic polyneuropathy: findings from three double-blind, placebo-controlled trials.

Migraines take a toll on employers as well!  -  May 6, 2007
News-Medical.net,The third analysis examined the impact of preventive treatment on workers who suffer from frequent migraines and suggested that use of TOPAMAX, (topiramate)

Women Taking Antiepileptics Give Birth to Babies at Risk ...  -  May 4, 2007
DG News...drugs observed in this study included valproate, lamotrigine, carbamazepine, levetiracetam, phenytoin, oxcarbazepine, gabapentin, and topiramate.

Employers Who Recognize The Impact Of Migraine May Help To Improve ...  -  May 4, 2007
Medical News Today (press release),...suffer from frequent migraines and suggested that use of TOPAMAX(R) (topiramate) may lead to fewer missed workdays and improve workplace productivity.

Migraine Prophylaxis With Topiramate May Reduce Lost Work Productivity  -  Apr 5, 2007
Medscape (subscription)NEW YORK (Reuters Health) Apr 05 - Preventive treatment with topiramate is associated with a reduction in lost productivity due to migraines,

Suicide Attempt Following Initiation of Topiramate  -  Apr 2, 2007
Am J Psychiatry (subscription)To the Editor: Topiramate is approved for monotherapy in partial seizures, generalized tonic clonic seizures, and migraine prophylaxis (1).

Drug combination proved deadly for Anna Nicole Smith  -  Apr 23, 2007
Citrus County Chronicle,Topiramate (Topamax — a drug used to treat seizures, migraines, obesity and other medical problems). * Acetaminophen (Tylenol — a pain reliever and fever

Migraines responsible for lost productivity  -  Apr 6, 2007
Independent Online,New York - Preventive treatment with topiramate (Topamax) is associated with a reduction in lost productivity due to migraines, researchers report.

Drug reduces work productivity lost to migraines  -  Apr 5, 2007
Scientific AmericanUsing data from two trials, Dr. Jennifer H. Lofland, of Thomas Jefferson University, Philadelphia, and colleagues examined whether topiramate use was

Drug killed desire to drink  -  Mar 30, 2007
Richmond Times Dispatch,Barnes was given topiramate, a drug that has been used to treat seizures and migraine headaches for years but is now being used by Johnson to treat addicts.

Research and Markets: New Report Analyzes Operations and Prospects ...  -  Apr 24, 2007
American Digital Networks (press release),R&D Projects Istradeylline Topiramate (KW-6485) Growth Forecast ANTI-INFECTIVE Marketed Products Itrizole Others Growth Forecast ANTICANCER Marketed

Addex looks to prevent migraines  -  Apr 24, 2007
DrugResearcher.com,The gold-standard for the prevention of migraines is Ortho-McNeil Neurologics' Topamax (topiramate). That drug is also used to prevent seizures in epilepsy

Research Finds Newer Drug For Partial Epilepsy Is Superior,But Old ...  -  Mar 29, 2007
Medical News Today (press release),In patients with partial epilepsy, carbamazepine was compared to newer drugs gabapentin, lamotrigine and oxcarbazepine and topiramate.

US District Court Grants Permanent Injunction Prohibiting Mylan ...  -  Apr 5, 2007
Drug Newswire (press release),Mylan filed an Abbreviated New Drug Application ("ANDA") to market topiramate before the expiration of the patent, claiming the patent was invalid.

Johnson & Johnson Pharmaceutical Research & Development, LLC ...  -  Apr 20, 2007
WebWire (press release),...our company’s major prescription medicines, such as TOPAMAX® (topiramate), ULTRAM® (tramadol HCl) and ULTRACET® (acetaminophen/tramadol hydrochloride).

The Moose in the Room  -  Apr 16, 2007
Scientist,...patents expire on two of J&J's top sellers: its schizophrenia drug Risperdal (risperidone) in 2008 and its epilepsy drug Topamax (topiramate) in 2009.

Trends in the Use of Psychotropic Drugs in Taiwan: A Population ...  -  Apr 5, 2007
Psychiatric Services (subscription)...valproate, gabapentin, topiramate, and lamotrigine), and anxiolytic-hypnotic drugs (including benzodiazepines and nonbenzodiazepine compounds).

Migraines? Ask Your Doctor About TPM  -  Mar 30, 2007
GNIF Brain Blogger,In 2006, the US Food and Drug Administration approved topiramate (brand name Topamax), also known as TPM, in 25-, 100-, and 200-mg tablet formulations for

March 27, 2007 | Got tips? E-mail: thefix@salon.com | IM ...  -  Mar 27, 2007
SalonA laundry list of drugs (including Benadryl, Klonopin, Valium, Ativan, atropine, topiramate, ciprofloxacin) combined with sleep drug chloral hydrate to

Lifting the Veil on Trichotillomania  -  Apr 2, 2007
Am J Psychiatry (subscription)Lochner C, Seedat S, Niehaus DJ, Stein DJ: Topiramate in the treatment of trichotillomania: an open-label pilot study. Int Clin Psychopharmacol 2006;

Eating Disorders: Binge Eating More Common Than Anorexia and Bulimia  -  Feb 5, 2007
U.S. News & World Report,Binge eating is typically treated with medications such as Topamax (topiramate) or Meridia (sibutramine) and with psychological and behavioral counseling.

New Jersey business briefs  -  Feb 14, 2007
NorthJersey.com,Topamax, or topiramate, treats epileptic seizures and helps prevent migraines. WAYNE -- Lamont Financial Services Corp. has won a one-year state contract to

Some facts about migraines  -  Feb 7, 2007
Pittsburgh Post Gazette,These include propranolol (Inderal), timolol (Blocadren), topiramate (Topamax) and divalproex sodium (Depakote). These have had many years of use and make

Survey: 3% Of Americans Are Binge Eaters  -  Feb 1, 2007
CBS News,..."The second is medications, especially topiramate [Topamax] and sibutramine [Meridia]," Hudson noted. "And finally, for individuals with severe obesity,

Binge eating is the most common eating disorder, McLean study shows  -  Feb 1, 2007
Boston Globe,Hudson reported receiving funding for the eating disorders analysis from OrthoMcNeil Neurologics, which has tested its antiepilepsy drug, topiramate,

Binge Eating: What you need to know  -  Feb 2, 2007
Food Consumer,...which helps people regulate their emotions; drug therapy with the anti-seizure medication topiramate; weight loss surgery (gastrointestinal surgery);

ADIPEX , adipex phentermine vs , adipex prescription , adipex diet ...  -  Dec 27, 2006
Indymedia Colombia,AdipexThe maximum strength, shine, smoothness, softness and muscle pain, tenderness, or adipex theophylline topiramate warfarin adip Order adipex from

Epilepsy drug treats sleep-related eating disorder  -  Dec 24, 2006
Zee News,Winkelman reviewed the cases of 30 patients with SRED who were treated with Topamax (known generically as topiramate) in a sleeping disorders clinic.

Spotlight on Epilepsy: Seizure disorder no longer bedevilling  -  Dec 9, 2006
New Straits Times,Topiramate is a favourite among women, claims Dr Raymond, as the patient loses between five and 10 per cent of total body weight after taking it.

No Weight Gain Seen in Patients on Investigative Antiepileptic ...  -  Dec 6, 2006
DG NewsHe also noted that topiramate, felbamate and zonisamide are associated with weight loss, he noted. Phenytoin, lamotrigine and leviteracetam are weight

Long-term use of topiramate and kidney-stones  Oct 31, 2006
Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraine headaches, can increase the propensity of calcium phosphate kidney stones ... -News-Medical.net, Topiramate Treatment Fails to Surpass Placebo for Restless Legs ...  Oct 11, 2006
CHICAGO, IL -- October 11, 2006 -- The anticonvulsant drug topiramate failed to distinguish itself from placebo in a study of patients with restless leg ... -DG News Drug Prescribed for Migraines and Seizures Increases Risk of ...  Oct 31, 2006
DALLAS, TX -- October 31, 2006 -- Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraine headaches, can increase the propensity of ... -DG News Long-term migraine drug use increases kidney stones risk  Nov 1, 2006
1: Researchers at UT Southwestern Medical Centre have found that the long-term use of topiramate (Topamax), a commonly prescribed drug for migraines and ... -South Asian Women's Forum, Migraine Drug Ups Kidney Stone Risk  Nov 1, 2006
Topamax (topiramate) has become one of the most commonly prescribed medications for migraine, Graybeal says, since it was approved for migraines by the FDA in ... -WebMD Study finds Topamax/kidney-stone link  Oct 31, 2006
Known by the chemical name topiramate, the widely prescribed neurological drug, when taken for about one year, seems to cause a condition called systemic ... -United Press International Migraine drug linked to kidney stones  Oct 31, 2006
A team from the UT South-western Medical Center discovered that taking topiramate could increase the propensity of calcium phosphate kidney stones. ... -TUV Product Service, More Details Reported on Promising Results for Experimental Diet ...  Oct 25, 2006
The experimental diet drug Qnexa -- which combines the diet pill phentermine and the active ingredient in Topamax (topiramate), a drug used to prevent ... -Diet Drug Report, Foro de Shell Security - Seguridad informática  Oct 26, 2006
...are character topamax zed by the level of differentiation, the size of th topicort cell of origin, the origin cell's rate of prolifer topiramate tion, and the ... -Shell Security, New Jersey business briefs  Oct 25, 2006
...of the drug last month. Topamax, or topiramate, treats epileptic seizures and helps prevent migraines. The medicine had sales of ... -NorthJersey.com, VIVUS' Qnexa Phase 2 Study Results Demonstrate Significant Weight ...  Oct 24, 2006
...is a proprietary pharmaceutical treatment that incorporates low doses of active ingredients from two previously approved products (phentermine and topiramate). ... -Drug Newswire (press release), US District Court Grants Request for Preliminary Injunction to ...  Oct 24, 2006
...prohibiting Mylan from launching a generic version of topiramate (TOPAMAX(R)) prior to a final court decision on the validity of the patent. ... -PR Newswire (press release), J&J Gets Injunction Against Mylan  Oct 24, 2006
Inc. preventing it from launching a generic version of topiramate before a final court ruling on the validity of the patent. Judge ... -Houston Chronicle, Obesity researchers study drug cocktails  Oct 22, 2006
In his study, Gadde used low doses of a seizure medication called topiramate as well as a common obesity pill, phentermine, which is usually recommended only ... -Boston Globe, Ortho-McNeil Neurologics Reveals US District Court's Preliminary ...  Oct 24, 2006
...(MYL | charts | news | PowerRating) prohibiting Mylan from launching a generic version of topiramate prior to a final court decision on the validity of the ... -Trading Markets, Market Report -- In Play (JNJ)  Oct 24, 2006
...subsidiary of JNJ, for a preliminary injunction against Mylan Laboratories (MYL) prohibiting MYLfrom launching a generic version of topiramate (TOPAMAX) prior ... -MSN Money Spotlight on Epilepsy: Seizure disorder no longer bedevilling  -  Dec 9, 2006
New Straits Times,Topiramate is a favourite among women, claims Dr Raymond, as the patient loses between five and 10 per cent of total body weight after taking it.

No Weight Gain Seen in Patients on Investigative Antiepileptic ...  -  Dec 6, 2006
DG NewsHe also noted that topiramate, felbamate and zonisamide are associated with weight loss, he noted. Phenytoin, lamotrigine and leviteracetam are weight

Topiramate for Co-Occurring Bipolar Disorder and Disruptive ...  Jul 28, 2006
To the Editor: Although studies have suggested that topiramate is helpful in the treatment of bipolar disorder, no study, to our knowledge, has examined its ... -Am J Psychiatry (subscription)

Treating Insomnia in Patients With Substance Use/Abuse Disorders  Aug 26, 2006
Other possibilities, like newer mood-stabilizing agents with sedating qualities (eg, topiramate [Topamax]), need to be explored. ... -Psychiatric Times

Help for Alcoholics - Research Summary  Aug 4, 2006
Bankole Johnson, MD chief of the University of Virginia's Department of Psychiatric Medicine, tested a new use for the medication topiramate. ... -ABC30.com

4BETTER OR WORSE- The week in review  Aug 24, 2006
...surveys the latest ways to stop smoking in the current Archives of Internal Medicine, and notes a couple of new drugs-- varenicline and topiramate-- that may ... -The Hook

Neurocognitive Effects of Psychotropic Anticonvulsants and Lithium  Aug 24, 2006
...disorder, aged 18-70 years, were treated with carbamazepine (CBZ) (N = 16), lamotrigine (LMTG) (N = 38), oxcarbazepine (OCBZ) (N = 19), topiramate (TPM) (N = 19 ... -Medscape (subscription)

Help for Alcoholics  Aug 4, 2006
You're consumed with consuming alcohol." But today, he can focus on other things -- like fishing -- thanks to a new drug called topiramate. ... -ABC30.com

In the best interest of patients?  Aug 18, 2006
Hmmmmmm. Let me preface what I'm going to say by noting that Topamax (topiramate) is an excellent preventive medication for many Migraineurs. ... -About - News & Issues

J&J Unit Gets Added Subpoena Over Marketing Of Topamax Drug  Aug 8, 2006
...a subpoena from the US Attorney's Office in Boston, seeking documents relating to the marketing, including alleged off-label marketing, of Topamax (topiramate ... -Easy Bourse (Communiqués de presse)

Systematic approach needed in managing chronic headaches  Aug 1, 2006
Another anticonvulsant, topiramate, even at low dosages, recently has produced very encouraging pediatric data to support its efficacy in chronic headache and ... -AAP News (subscription)

Diverse challenges await generics industry  Aug 7, 2006
Merck's Zetia (ezetimibe) and Cozaar (losartan), GSK's Avandia (rosaglitazone) and Johnson & Johnson's Levaquin (levofloxacin) and Topamax (topiramate). ... -PipelineReview.com

FACETIME- Pill cure? UVA doc sees Mel's fix  Aug 10, 2006
Researching a drug called topiramate, Johnson discovered that people who took the drug were six times more likely to quit drinking than those receiving a ... -The Hook

Research Summary: Stop Addiction  Jul 19, 2006
Bankole Johnson, MD chief of the University of Virginia's Department of Psychiatric Medicine, tested a new use for the medication topiramate. ... -abc7news.com

Existing Drug May Help Stop Alcoholism  Jul 19, 2006
You're consumed with consuming alcohol.". But today, Tom can focus on other things, like fishing, thanks to a new drug called Topiramate. ... -abc7news.com

After weight-loss surgery, some find new addictions  Jul 18, 2006
Topiramate, an epilepsy drug marketed by Ortho-McNeil Neurologics under the name Topamax, is currently being studied for binge eating, alcohol dependence ... -Pittsburgh Post Gazette

AHS: Epilepsy Drug Reduces Frequency of Chronic Migraines  Jun 26, 2006
They found that off-label use of the anti-epilepsy drug Topamax (topiramate) can cut the frequency of migraine events for chronic sufferers or the number ... -MedPage Today

Generic pie to grow bigger but also carved up into smaller pieces  Jul 10, 2006
Zetia (ezetimibe) and Cozaar (losartan), GlaxoSmithKline 's Avandia (rosaglitazone) and Johnson & Johnson's Levaquin (levofloxacin) and Topamax (topiramate). ... -In-PharmaTechnologist.com

Diverse challenges await generics industry  Jul 7, 2006
Merck's Zetia (ezetimibe) and Cozaar (losartan), GSK's Avandia (rosaglitazone) and Johnson & Johnson's Levaquin (levofloxacin) and Topamax (topiramate). ... -Pharmaceutical Business Review

Abdominal Migraine and Treatment With Intravenous Valproic Acid  Jul 14, 2006
...basis. "A" experienced side effects of weight gain that led to the addition of topiramate in an effort to regulate her appetite. ... -Psychosomatics (subscription)

Magnetic Stimulation May Ease Migraine Pain  Jun 22, 2006
Another study presented at the meeting found that the anti-seizure medication Topamax (generic name topiramate) provided relief to people who have migraine ... -Forbes

AN ANTI-ADDICTION PILL?  Jun 25, 2006
...addiction." (Vocci says that it isn't yet clear whether the absence of GABA is a cause of addiction or a result.) The seizure medication topiramate, for example ... -Amherst Times.com

Shingles and Chickenpox (Varicella-Zoster Virus)  Jun 23, 2006
Newer anti-seizure agents, including lamotrigine, oxcarbazepine, topiramate, and zonisamide, are being investigated but no data supports their use for PHN as ... -About - News & Issues

What Happened to Lithium? Antidepressant Augmentation in Clinical ...  Jun 30, 2006
The anticonvulsants considered included carbamazepine, oxycarbamazepine, divalproex/valproic acid, lamotrigine, and topiramate. ... -Am J Psychiatry (subscription)



Orlistat and Metformin Protect Against Antidepressant-Associated ...  Mar 27, 2006
In addition, 2 patients received the antiepileptic agent topiramate, 50-400 mg/day, but dropped out of the study due to adverse effects. ... - DG News

Interaction of Duloxetine and Warfarin Causing Severe Elevation of ...  Apr 4, 2006
She had been taking a stable regimen of atorvastatin, 10 mg/d; warfarin, 7.5 to 10 mg/d; lamotrigine, 50 mg/d; topiramate, 200 mg/d; clonazepam, 2 mg/d; and ... - Journal of American Medical Association (subscription)

Stimulating: Prescribing Amidst Controversy  Apr 3, 2006
...for girls liable to polycystic ovary syndrome, lamotrigine too risky for children at heightened risk for Stevens-Johnson syndrome, and topiramate, even when ... - Am J Psychiatry (subscription)

New Hope for Addicts?  Mar 18, 2006
...the brew. Then, in 1998, Elbel volunteered for a clinical trial of a drug called topiramate, a well-known seizure medication. He ... - Standard-Speaker

Managing Compliance  Apr 2, 2006
Several agents, such as topiramate (Topamax) (McIntyre et al., 2001), nizatidine (Axid) (Sacchetti et al., 2000), and amantadine (Floris et al., 2001) have ... - Psychiatric Times

Sperling's BestPlaces Uncovers Migraine ‘Hot Spots' In The US  Mar 10, 2006
On the contrary, there are various options including lifestyle changes, and for some, daily migraine prevention treatments like TOPAMAX® (topiramate) that can ... - Medical News Today

Prescription drug purchases by Canadian hospitals and pharmacies ...  Mar 15, 2006
...name drugs which faced generic competition for the first time in 2005 were the anti- depressant Wellbutrin(R) (bupropion), Topamax(R) (topiramate) - used to ... - Canada NewsWire

`It's Cool To Figure Out How We Work'  Mar 8, 2006
Farley's topic? "Chronic stress-related reduction of microglial proliferation in the Hilus of the Dorsal Hippocampus is reversed by Topiramate.". ... - Hartford Courant



Teva gets added Topamax tentative FDA OK  07 Mar 2006
...unit Ortho McNeil. The approval covers a 50 milligram tablet of topiramate, the active ingredient of Topamax. A tentative approval ... - BusinessWeek

Sperling's BestPlaces Uncovers Migraine 'Hot Spots' in the US  07 Mar 2006
TOPAMAX(R) (topiramate) Tablets and Sprinkle Capsules, approved for the prevention of migraine headaches in adults by the US Food and Drug Administration in ... - PR Newswire,

Medical Edge: Many drug options for migraines  Feb 11, 2006
Antiseizure drugs including gabapentin and topiramate that are used to treat epilepsy also seem to prevent migraine headaches. ... - Bryan College Station Eagle,

Guideline Watch: Practice Guideline for the Treatment of Patients ...  Jan 23, 2006
In a double-blind controlled study involving 64 patients for 10 weeks, topiramate demonstrated efficacy in treating bulimia nervosa (56, 57). ... - Focus (subscription)

The Diagnosis and Treatment of Substance Abuse/ Dependence and Co ...  Jan 23, 2006
Am J Psychiatry 154(2):239-242. Van Ameringen M, Mancini C, Pipe B et al. (2004), An open trial of topiramate in the treatment of generalized social phobia. ... - Psychiatric Times

Managing migraine with drugs, lifestyle changes  Jan 10, 2006
Some anti-seizure drugs (such as gabapentin and topiramate) that are used to treat epilepsy also seem to prevent migraine headaches. ... - NorthJersey.com

Johnson & Johnson: Fourth Quarter and Year End 2005 Financial ...  Jan 24, 2006
REMICADE® (infliximab), a biologic approved for the treatment of a number of Immune Mediated Inflammatory Diseases; TOPAMAX® (topiramate), an antiepileptic ... - PharmaLive.com

Bibliography FOR SLEEP, SEX, AND EATING DISORDERS  Jan 23, 2006
McElroy SL, Arnold LM, Shapira NA, Keck PE Jr, Rosenthal NR, Karim MR, Kamin M, Hudson JI: Topiramate in the treatment of binge eating disorder associated with ... - Focus (subscription)

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