Recent news on Vaccinia

Cangene's VIG (Vaccinia Immune Globulin Intravenous) Approved by ...  -  25 May 2007
PharmaLive.com (press release),TORONTO and WINNIPEG, May 24, 2007/CNW/ - Cangene Corporation today reports that it has received a Notice of Compliance ("NOC") for its Vaccinia Immune

PRESIDENT’S ADDRESS AT THE CONVOCATION OF THE PT. BD SHARMA POST ...  -  25 May 2007
Press Information Bureau (press release),Another vaccine is undergoing phase-I trials at the Tuberculosis Research Centre for the Modified Vaccinia Ankara (MVA) based vaccine developed from the

CDC reports sexual transmission of vaccinia  -  May 4, 2007
CIDRAP,May 4, 2007 (CIDRAP News) – A woman from Alaska experienced vulvar vaccinia after she was intimate with a US military member who had received his smallpox

Soldier’s Smallpox Inoculation Sickens Son  -  May 18, 2007
Tuscaloosa News (subscription),Vaccinia is the live virus used in smallpox vaccine. After vaccination, the body develops a resistance to vaccinia, a disease that is generally milder than

Toddler survives smallpox  -  May 18, 2007
Macon Area Online,The smallpox vaccine uses a related and usually harmless virus called vaccinia. It is scratched into the skin and forms a pustule that scabs over and falls

The long shadow of smallpox  -  May 8, 2007
ScienceBlogsThe vaccinia virus, thought to be a derivative of cowpox, has been used in the 20th century in smallpox vaccination campaigns.

FDA Advisers Back New Smallpox Vaccine  -  May 18, 2007
My Fox Boston,Like Dryvax, the Acambis vaccine is made using a relative of the smallpox virus called vaccinia. FDA scientists who reviewed studies of the new version

CDC: Smallpox shot passed via sex  -  May 3, 2007
United Press InternationalVaccinia is the virus used in the smallpox vaccine, but it is different from the smallpox vaccine and cannot cause the deadly disease. Vaccinia can, however

Woman gets smallpox-vaccine virus via sex  -  May 3, 2007
MSNBCThe infection was from the vaccinia virus, the type of virus contained in the smallpox vaccine. Vaccinia is closely related but less virulent than the

US woman gets genital rash from smallpox vaccinee  -  May 3, 2007
Scientific American..."After vaccinia was identified, investigators interviewed the woman more closely and learned that her new sex partner was a male US military service member

Woman Gets Virus After Sex With Vaccinated Serviceman  -  May 4, 2007
Vaccine Rx (press release),The CDC was able to identify the virus as a vaccine-strain of the vaccinia virus, a closely related strain to the variola, or smallpox, virus.

SLU Scientist Leads National Smallpox Study  -  May 4, 2007
Medical News Today (press release),The Dryvax® vaccine is made from a live virus called vaccinia. The only people who presently receive this vaccine are people who work with viruses

Omrix Q1 profit up 25% to $14.2m  -  May 9, 2007
Globes,The guidance assumes no sales of VIG (Vaccinia Immunoglobulin), a late launch of Thrombin, and no material effect from the General Hemostasis approval of

Mo. university to lead smallpox study  -  Apr 30, 2007
MLive.com,Imvamune is a weakened form of the vaccinia virus, used to protect against smallpox. "The main point of the study is to see if it takes less time to make

Mo. university to lead smallpox study  -  Apr 30, 2007
The Westfall Weekly News,Imvamune is a weakened form of the vaccinia virus, used to protect against smallpox. The test vaccine will be studied alone, and in combination with Dryvax.

Dramatic rescue relieves rare case of smallpox infection  -  Apr 26, 2007
Nature.com (subscription),Two weeks later, his son presented with symptoms of eczema vaccinatum, a rare and dangerous skin infection caused by the vaccinia virus used in the vaccine.

FDA panel recommends smallpox vaccine approval  -  May 18, 2007
CIDRAP,ACAM2000 uses vaccinia virus, a close relative of smallpox, and is grown in cell culture. It is derived from Dryvax, a first-generation vaccine that was

Smallpox Vaccine Gets Good FDA Reviews  -  May 15, 2007
WTOP,Dryvax and ACAM2000 both are made using the vaccinia or cowpox virus, which is closely related to the smallpox virus. In 1980, world health authorities

Toddler Infected With Rare Side Effect Of Smallpox Vaccination ...  -  May 22, 2007
MedIndia,...had eczema in childhood, should never have been given the vaccine because that fact made him more susceptible to side effects like vaccinia infection.

US Developments Enhance Bavarian Nordic's Strategic Position  -  May 2, 2007
PharmaLive.com (press release),The intent by HHS to procure 20 million doses of a new smallpox vaccine is based on the Modified Vaccinia Ankara (MVA) virus which does not replicate in

Destruction of smallpox virus delayed  -  May 18, 2007
MSNBCLike Dryvax, the Acambis vaccine is made using a relative of the smallpox virus called vaccinia. Both are live-virus vaccines, and FDA scientists who

Lincoln's smallpox?  -  May 18, 2007
ScienceBlogsAlternatively, one could go straight to the source and look for an outbreak of vaccinia in cows, but this was unpredictable and, as one can imagine,

This Week in Health  -  May 18, 2007
Intelihealth.com,Both vaccines are made from the vaccinia or cowpox virus, and both vaccines carry a risk of side effects including itching, rash and pain and, in rare cases

Bradley Pharmaceuticals Flora-Q(R)2 Probiotic Featured at ...  -  May 18, 2007
Earthtimes.orgAnaMantle HC(R) 2.5% Gel is contraindicated for tuberculous or fungal lesions, skin vaccinia, varicella or acute herpes simplex. AnaMantle HC(R) 2.5% Gel

Common cold virus could kill cancer  -  May 17, 2007
Hindustan Times,The two viruses likely to be used in the first trials are adenovirus, which normally causes a cold-like illness, and vaccinia, which is used in the vaccine

Bavarian Nordic Appeals Delaware Order Dismissing Claims Related ...  -  May 17, 2007
PharmaLive.com (press release),Anton Mayr, the pioneering creator of Modified Vaccinia Ankara (MVA) used to make Bavarian Nordic’s smallpox vaccine IMVAMUNE®, had supplied a specific

Bavarian Nordic loses smallpox vaccine case to Acambis  -  May 16, 2007
Pharmaceutical Business ReviewBavarian Nordic had claimed that Professor Anton Mayr, the creator of modified vaccinia Ankara (MVA) used to make Bavarian Nordic's smallpox vaccine

Dramatic rescue relieves rare case of smallpox infection  -  26 Apr 2007
Nature.com (subscription),Two weeks later, his son presented with symptoms of eczema vaccinatum, a rare and dangerous skin infection caused by the vaccinia virus used in the vaccine.

HHS offers plan for defense against biological threats  -  26 Apr 2007
CIDRAP,The agency "is well advanced in the pre-award stage" of a program to buy one such vaccine, called modified vaccinia Ankara, it says.

Smallpox Vaccine Causes Rare Complications  -  Apr 24, 2007
PBSJOHN MARCINAK: I said, "This is amazing," and we have to work on getting vaccinia immune globulin from the Centers for Disease Control.

Danish firm expects to sell smallpox vaccine to US  -  Apr 18, 2007
CIDRAP,Imvamune is Bavarian's version of modified vaccinia Ankara (MVA), which is considered safer than the conventional smallpox vaccine, particularly for people

Plants used to make vaccines  -  Apr 18, 2007
Monterey County Herald,The original smallpox vaccine (which permitted eradication of the disease in the 1970s) was a weakened version of vaccinia virus that provided immunity

Dad's vaccination hospitalizes boy, 2  -  Apr 9, 2007
Indianapolis Star,The boy is not suffering from smallpox, but from the related vaccinia virus which is used to convey immunity to the much deadlier disease.

New drug aids child sickened by dad’s vaccine  -  Apr 13, 2007
MSNBCOther therapies included an intravenous form of vaccinia immune globulin — developed in the 1960s to treat complications of smallpox vaccinations.

UCH treats infection from smallpox vaccine  -  Mar 30, 2007
Chicago Maroon,He has been treated with vaccinia immune globulin, the antiviral drug cidofovir, and the experimental antiviral treatment ST-246.

Novel drugs help kid sick from dad's smallpox jab  -  Apr 13, 2007
ReutersSmallpox vaccines do not use the smallpox virus, but a closely related and weaker virus called vaccinia. Those who have eczema, like the toddler,

Bavarian Nordic will tender to supply Canada with MVA-based ...  -  Apr 10, 2007
Forbes,...supply of Modified Vaccinia Ankara (MVA) based smallpox vaccines for the protection of 10000 people and an option for protecting another 10000 people.

US Government Notifies Bavarian Nordic of Intent to Acquire 20 ...  -  Apr 16, 2007
PharmaLive.com (press release),The vaccinia virus found in traditional smallpox vaccines used and/or stockpiled today, are live, replicating viruses which can pose serious side-effects

New treatment aids toddler with rare ailment  -  Apr 13, 2007
Scientific AmericanOther therapies included an intravenous form of vaccinia immune globulin -- developed in the 1960s to treat complications of smallpox vaccinations.

Bangalore: ‘HIV vaccine trial showing good response’  -  Apr 14, 2007
Bellevision,We are now going for a combined vaccine trail with Adeno Associated Virus (AAV) and Modified Vaccinia Ankara (MVA) and taking it to Phase One.

Africa: All Not Well With Global Aids Vaccine Trials  -  Apr 13, 2007
AllAfrica.com,The Pune site was originally being prepared for TBC-M4 (Modified Vaccinia Ankara HIV-1 multigenic subtype C) to be tested at NARI.

Pollin Prize Awarded To Dr. Samuel L. Katz For His Role In ...  -  Apr 13, 2007
Medical News Today (press release),In addition to his investigations of measles, Dr. Katz has been involved in studies of vaccinia, polio, rubella, influenza, pertussis,

Transgene and Roche Enter Partnership on Therapeutic Vaccines ...  -  Apr 11, 2007
CNW Telbec (Communiqués de presse),TG 4001 (MVA-HPV-IL2) is based on a non-propagative, highly attenuated vaccinia vector (MVA), which is engineered to express HPV16 antigens and an adjuvant.

Transgene, Roche Enter Potential $293M Alliance On HPV Vaccine  -  Apr 11, 2007
BioWorld Online,TG 4001 is based on a non-propagative, highly attenuated vaccinia vector (MVA) engineered to express HPV16 antigens, and an adjuvant.

FDA Approves Cangene's HepaGam B for Liver Transplant Recipients  -  Apr 9, 2007
eMaxHealth.com,Cangene manufactures HepaGam B in its Winnipeg facility using a process similar to that of WinRho(R) SDF, Vaccinia Immune Globulin and VariZIG,

FDA approves Cangene's HepaGam B(TM) for a second indication; for ...  -  Apr 9, 2007
Drug Newswire (press release),Cangene manufactures HepaGam B(TM) in its Winnipeg facility using a process similar to that of WinRho(R) SDF, Vaccinia Immune Globulin and VariZIG(TM),

In Brief  -  Apr 3, 2007
Nature.com (subscription),...to its failure to secure an expected US Project Bioshield (biodefense) contract worth up to $200 million for Modified Vaccinia Ankara smallpox vaccine.

Gene Therapy Gains Boost With $690M Collaboration  -  Apr 3, 2007
BioWorld Online,The product, which is in Phase III for the treatment of renal cancer, uses a vaccinia viral vector to deliver the gene for 5T4, an antigen that is expressed

Bavarian Nordic Obtains License to Vivalis’ ESC-derived Cell Lines  -  Mar 30, 2007
Genetic Engineering News (press release),Vivalis granted Bavarian Nordic rights to evaluate the embryonic stem cell derived EBx® cells as a production platform of MVA-BN®-based (modified vaccinia

Son of vaccinated soldier has severe vaccinia infection  -  Mar 19, 2007
CIDRAP,Mar 19, 2007 (CIDRAP News) – A 2-year-old Indiana boy is in critical condition in a Chicago hospital with eczema vaccinatum, a rare type of vaccinia virus

Toddler Contracts Infection from Father's Smallpox Vaccine  -  Mar 18, 2007
Associated Content,The young boy was being medicated with potent antiviral drug, as well as with an anti-vaccinia agent supplied by the Centers for Disease Control and the

Report: Toddler contracts rare infection  -  Mar 18, 2007
Hinesberg Journal,Physicians stressed that the boy was not suffering from smallpox, but from the related vaccinia virus which is used to convey immunity to the much deadlier

Smallpox shot infects soldier's toddler son  -  Mar 17, 2007
Chicago Tribune,For that reason, experts want to study the Indiana family to learn more about treatment and transmission of the vaccinia infection.

Smallpox vaccine infection called rare  -  Mar 20, 2007
Gary Post Tribune,A combination of exceptional factors likely led to the boy's infection with the vaccinia virus, which apparently also was passed to his mother, who suffered

Mom, tot sick from dad's smallpox shot  -  Mar 18, 2007
Edmonton Sun,Doctors stressed that the boy was not suffering from smallpox, but from the related vaccinia virus which is used to convey immunity to the much deadlier

Father's vaccine infects boy, 2  -  Mar 18, 2007
The Courier News,Physicians stressed that the boy is not suffering from smallpox, but from the related vaccinia virus that is used to convey immunity to the much deadlier

Boy severely infected from father's vaccination, paper reports  -  Mar 18, 2007
Chicago Daily Southtown,Physicians stressed that the boy is not suffering from smallpox but from the related vaccinia virus, which is used to convey immunity to the much deadlier

Army dad's smallpox vaccine makes Hammond baby gravely ill  -  Mar 17, 2007
nwitimes.com,..."In some circumstances, vaccinia virus can cause serious illness. In this case, the child is currently in intensive care in critical condition."

US toddler improving on smallpox drug  -  Mar 20, 2007
Sydney Morning Herald,Smallpox vaccines do not use the smallpox virus, but instead use a related virus called vaccinia that is weakened but can still infect some people.

Report: Soldier vaccination infects child  -  Mar 17, 2007
ArmyTimes.com,Physicians stressed that the boy is not suffering from smallpox, but from the related vaccinia virus which is used to convey immunity to the much deadlier

Dad's smallpox shot infects son, 2  -  Mar 18, 2007
Chicago Sun-Times,His son, who suffers from skin lesions known as eczema, then became infected by vaccinia, a virus similar to smallpox and used in the vaccine against it.

Soldier's, son, wife infected by vaccine  -  Mar 18, 2007
Indianapolis Star,Physicians stressed that the boy was not suffering from smallpox, but from the related vaccinia virus, which is used to convey immunity to the much deadlier

Smallpox vaccine infects boy  -  Mar 18, 2007
Gary Post Tribune,The boy suffers from skin lesions known as eczema, and became infected by vaccinia, a virus similar to smallpox and used in the vaccine against it.

Smallpox vaccine and skin diseases  -  Mar 18, 2007
Blogger News NetworkOriginally it was cowpox, but over the last 200 years it has become a different virus, called vaccinia. For most people, it would cause a sore– an open sore

Vaccine infects mom, tot  -  Mar 18, 2007
Canoe.ca,Doctors said the boy was not suffering from smallpox, but from the related vaccinia virus which is used to convey immunity to the much deadlier disease.

Child Develops Eczema Vaccinatum After Father Has Smallpox Vaccination  -  Mar 19, 2007
Medscape (subscription)Because smallpox vaccine uses live vaccinia virus, it can sometimes cause severe and sometimes fatal side effects. "The child is a dependent of a US Army

Child in hospital after father has smallpox jab  -  Mar 19, 2007
Scientific AmericanThe smallpox vaccine is made using a closely related virus called vaccinia. It is scratched into the surface of the skin, where it causes a mild infection

Soldier Infects Toddler Son With Life-Threatening Illness  -  Mar 19, 2007
Associated Content,It was this condition that allowed for the vaccinia virus to enter his body after coming into contact with his recently vaccinated father.

Smallpox Vaccination Leaves Soldier's Son with Life Threatening ...  -  Mar 18, 2007
News Locale,The condition is related to the vaccinia virus, which is used as a means of bestowing immunity from smallpox. Eczema vaccinatum has not been officially

Vaccine rubs off on son  -  Mar 18, 2007
Toronto Sun,Doctors said the boy was suffering from vaccinia virus, which is used to convey immunity to smallpox, and may lose 20% of his outer skin layer.

OMRIX Biopharmaceuticals Announces Fourth Quarter and Full-Year ...  -  Mar 9, 2007
PharmaLive.com (press release),Full-year 2006 product sales of $56.9 million, include $21.2 million from a contract with the UK government for the purchase of Vaccinia Immunoglobulin,

PBMC display 90% viability for T cell responses  -  Mar 25, 2007
Laboratory Talk,...antigen reactivity, age, gender, ethnicity, blood type, and vaccination status for vaccinia, TB, and hepatitis B. Custom orders are also available.

Oxford BioMedica Buying Oxxon In Share Offering Valued At £16M  -  Mar 13, 2007
Therapeutics Daily (subscription) (press release),Designed as a modified vaccinia ankara (MVA) vaccine encoding seven epitopes derived from melanoma antigens, Hi-8 MEL offers ?a good complement? to Oxford

Omrix Q4 sales up 117%  -  Mar 11, 2007
Globes,Omrix’s 2006 sales received a boost thanks to a $21.2 million contract with the British government for the purchase of Vaccinia Immunoglobulin (VIG).

Omrix Biopharmaceuticals profit soars  -  Mar 8, 2007
BusinessWeekIt also credited greater revenue to a contract with the UK government for Vaccinia Immunoglobulin. For all of 2006, Omrix had a profit of $23.1 million,

In Vivo Inhibition of Growth of Human Tumor Lines by Flavonoid ...  -  Feb 27, 2007
Cancer Focus,Semipurified, flavonoid-rich extracts of cranberry (Vaccinia macrocarpa) were shown previously to arrest proliferation of tumor cells and induce apoptosis.

Poxvirus Expert To Speak March 29  -  Mar 22, 2007
PressZoom (press release),Smallpox ( variola ), monkeypox, vaccinia and cowpox are examples of orthopoxviruses. Following an aggressive global vaccination program,

SIGA (SIGA) Said Smallpox Drug Used on Human Patient  -  Mar 19, 2007
StreetInsider.com (subscription),...following accidental contact with an open skin lesion on a relative who had recently been vaccinated for smallpox using a live vaccinia virus vaccine.

NATION IN BRIEF  -  Mar 18, 2007
Washington Post,Physicians stressed that the boy was not suffering from smallpox, but from an infection with the related vaccinia virus that is used to convey immunity to

Smallpox shot infects soldier's son  -  Mar 18, 2007
Food Consumer,It is vaccinia, a similar, yet milder virus that is used in the vaccine to induce immunity against smallpox. The spread of viruses in a smallpox vaccine

Cangene reports results for second quarter of fiscal 2006  -  Mar 16, 2007
PharmaLive.com (press release),Revenue for the quarter was up due to sales of Vaccinia immune globulin (VIG) to the UK, which more than offset reduced WinRho(R) SDF sales in the US that

Cangene's HepaGam Added To Novation's Product Listing  -  Mar 15, 2007
HULIQ,Cangene manufactures HepaGam B(TM) in its Winnipeg facility using a process similar to that of WinRho(R) SDF and Vaccinia immune globulin, the Company's

Oxford BioMedica Buys Oxxon, In Share Offering Valued At €16M  -  Mar 13, 2007
BioWorld Online,Oxxon's products use sequential immunization with two different vectors - a DNA plasmid followed by modified vaccinia Ankara - carrying the genes for the

Oxford BioMedica Buying Oxxon In Share Offering Valued At £16M  -  Mar 12, 2007
BioWorld Online,Designed as a modified vaccinia ankara (MVA) vaccine encoding seven epitopes derived from melanoma antigens, Hi-8 MEL offers "a good complement" to Oxford

Vaccine maker shakes up top brass  -  Mar 7, 2007
Guardian Unlimited,Last November, Acambis lost out on a major contract with the US government, potentially worth $1bn, to supply the weakened modified vaccinia ankara (MVA)

University Events  -  Mar 7, 2007
Washington University Record,..."The Intricate Choreography of Vaccinia Virus Replication and Morphogenesis." Paula Traktman, prof. and chair of microbiology & molecular genetics,

Vaccinex Financing Targets $25M, Signs Deal With Teva  -  Feb 27, 2007
BioWorld Online,The ActivMab approach uses a vaccinia virus-based vector to express the antibodies in mammalian cells, thereby gaining high levels of combinatorial

US International Trade Commission Refers MVA Case Back to the ...  -  Feb 26, 2007
Drug Newswire (press release),Initial Determination in a case in which Bavarian Nordic's patents on the Modified Vaccinia Ankara virus (MVA) were found to be infringed but invalid.

US International Trade Commission Refers MVA Case Back to the ...  -  Feb 22, 2007
netPR.pl (komunikaty prasowe),Initial Determination in a case in which Bavarian Nordic's patents on the Modified Vaccinia Ankara virus (MVA) were found to be infringed but invalid.

US International Trade Commission Refers MVA Case Back to the ...  -  Feb 22, 2007
Earthtimes.org...the Initial Determination in a case in whichBavarian Nordic's patents on the Modified Vaccinia Ankara virus (MVA) werefound to be infringed but invalid.

Bavarian Nordic Raising $82M In Discounted Rights Offering  -  Feb 20, 2007
BioWorld Online,...contract to supply 20 million doses of its next-generation safe smallpox vaccine Imvamune, which is based on the modified Vaccinia ankara (MVA) vector.

Transgene Initiates A Phase I Trial Of Its Therapeutic Vaccine ...  -  Feb 15, 2007
Medical News Today (press release),The MVA vector is a highly attenuated strain of vaccinia virus that combines an extensive history of safety with the ability to stimulate a strong immune

Symphogen receives $5 Million Euro investment from Gilde ...  -  Feb 1, 2007
American Venture Magazine (press release),...as well as to further advance additional Symphogen programs for vaccinia virus, anti-respiratory syncytial virus, and oncology.�

President's address and interaction with the students of Kurnool ...  -  Feb 2, 2007
Nanotechnology News (press release)Another Phase-I vaccine trial was initiated last year at the Tuberculosis Research Centre for the Modified Vaccinia Ankara (MVA) based vaccine developed

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