Recent news on Vinorelbine

Prostate Cancer: Clinical Study Demonstrates Superior Efficacy of ...  -  25 May 2007
openPR (press release),However, other clinical trials indicated that the drug vinorelbine, which like docetaxel acts on cellular microtubuli, also produces impressive results and

Prostate Cancer: Clinical Study Shows Superior Efficacy of ...  -  May 23, 2007
Business Portal 24 (press release),However, other clinical trials indicated that the drug vinorelbine, which like docetaxel acts on cellular microtubuli, also produces impressive results and

ADVENTRX Pharmaceuticals Reports First Quarter 2007 Financial Results  -  May 7, 2007
PR Newswire (press release),The increase in R&D expenses was primarily due to a $377000 increase related to pre-clinical development of ANX-530 (vinorelbine emulsion) and preclinical

Lung Cancer is the Third Most Common Malignant Disease and the ...  -  May 13, 2007
Fuerteventura Digital,These two drugs are combined with paclitaxel, docetaxel, gemcitabine or vinorelbine to build the first-line treatment options.

Kyowa Hakko Kogyo submits NDA for Parkinson's drug  -  Apr 30, 2007
Pharma Times (subscription),...antihypertensive Coniel (benidipine), but the anti-allergy drug Allelock (olopatadine) and the anticancer agent Navelbine (vinorelbine) performed well.

Cancer Genes Linked to Chemotherapy Sensitivity  -  Apr 12, 2007
Genetic Engineering News (press release),...and tried the same test using chemotherapy drugs Vinorelbine and Gemcitabine, but the results were not as dramatic as those seen for Paclitaxel.

The code that could unlock cancer  -  Apr 19, 2007
CNN International...common chemotherapy drugs such as vinorelbine and gemcitabine, said Angelique Whitehurst, the lead author on the Southwestern Medical Center study.

Massive Gene Screening Points Way To More Effective Chemotherapy  -  Apr 15, 2007
Medical News Today (press release),...test using the chemotherapy drugs vinorelbine (Navelbine) and gemcitabine (Gemzar), but the results were not as dramatic as those seen for paclitaxel.

Study uncovers genes which affect chemotherapy impact  -  Apr 13, 2007
Cancer Research UK - News & Resources,Postdoctoral researcher Dr Angelique Whitehurst explained that tests involving other chemotherapy drugs, vinorelbine (Navelbine) and gemcitabine (Gemzar),

Breakthrough in cancer treatment could provide less traumatic ...  -  Apr 13, 2007
Daily Mail,Six genes showing the most dramatic effect were re-tested using the drugs vinorelbine and gemcitabine, with weaker results.

Revolution in cancer treatment  -  Apr 12, 2007
Belfast Telegraph,The scientists also tested the RNA-i approach using other anti-cancer drugs, such as gemcitabine and vinorelbine, but they did not see the dramatic effects

Pharma Sector: Few Newsmakers Of The Week - Merck, Pfizer, Mylan ...  -  Apr 14, 2007
Trading Markets,...when compared to patients who received one of the control agents, Vinorelbine approved in the United States for treating first-line lung cancer.

INEX Releases 2006 Operating Results and Announces 2007 Corporate ...  -  Apr 4, 2007
Drug Newswire (press release),...targeted chemotherapy products - Marqibo(R) (sphingosomal vincristine), INX-0125 (sphingosomal vinorelbine) and INX-0076 (sphingosomal topotecan).

Neoadjuvant Taxotere®, Navelbine® and Herceptin® Active for ...  -  Apr 4, 2007
Cancer Consultants (press release),Phase II study of neoadjuvant docetaxel, vinorelbine, and trastuzumab followed by surgery and adjuvnt doxorubicin pluw cyclophosphamide in women with human

Hana Biosciences Announces Fourth Quarter and Year-End 2006 Results  -  Mar 29, 2007
Primenewswire (press release),Initiated a Phase I clinical study of Alocrest(tm) (vinorelbine tartrate liposomes injection) in patients with advanced solid tumors.

Vinorelbine/Cisplatinum May Help Bladder Cancer Patients ...  -  Feb 9, 2007
DG NewsPARIS, FRANCE -- February 9, 2007 -- The combination of cisplatinum and vinorelbine has demonstrated a favorable response rate in patients with locally

Addition of Gemzar® to Navelbine® Improves Progression-free ...  -  Feb 16, 2007
Cancer Consultants (press release),According to an article recently published in Lancet Oncology, the addition of the chemotherapy agent Gemzar® (gemcitabine) to Navelbine® (vinorelbine)

Solo Capecitabine Shows Good Results in Advanced Breast Cancer ...  -  Feb 6, 2007
DG NewsAmong the 94 patients who received further chemotherapy, 80 (85%) received a taxane, 38 (40%) received anthracycline, and 35 (37%) received vinorelbine.

Pipeline match for possible Bristol-Myers Squibb and Sanofi ...  -  Jan 31, 2007
In-PharmaTechnologist.com,Ixabepilone is a semi-synthetic analogue of epothilone B whereas Javlor (vinflunine) is a vinca alkaloid synthesised from vinorelbine.

Threshold Pharmaceuticals Initiates Phase 2 Clinical Trial ...  -  Jan 30, 2007
PipelineReview.com (press release),...including topotecan, anthracyclines such as doxorubicin, gemcitabine, cyclophosphamide, vinorelbine, hexamethylmelamine, ifosfamide, and etoposide.

Data acquisition for the histoculture drug response assay in lung ...  -  Jan 31, 2007
The Journal of Thoracic and Cardiovascular SurgerySequential therapy in advanced non-small-cell lung cancer with weekly paclitaxel followed by cisplatin-gemcitabine-vinorelbine. A phase II study.

ADVENTRX Cleared To Initiate Vinorelbine Emulsion Bioequivalence Study  -  Dec 29, 2006
Medical News Today (press release),The study is a multicenter, open-label, randomized crossover comparison of ANX-530 and the approved reference product Navelbine(R) (vinorelbine tartrate) in

Market Report -- In Play (ANX)  -  Dec 26, 2006
MSN MoneyADVENTRX Pharma cleared to initiate vinorelbine emulsion bioequivalence study Co announces its Investigational New Drug application for the clinical

ADVENTRX Pharmaceuticals (ANX) Says FDA Accepts INDA for Clinical ...  -  Dec 26, 2006
StreetInsider.com (subscription),..."We believe ANX-530 will show bioequivalence to the marketed form of vinorelbine," said Evan M. Levine, chief executive officer of ADVENTRX.

Capecitabine Plus Bevacizumab Combination May Produce Clinical ...  -  Dec 20, 2006
DG NewsClinical investigators chose whether the patient received paclitaxel or vinorelbine. In an interim study analysis of 103 patients from a total of 109

Re-Induction Chemotherapy May Improve Survival for Some Patients ...  -  Jan 2, 2007
Cancer Consultants (press release),This trial included 48 patients who were all initially treated with 6 courses of PEV (Platinol® (cisplatin), Ellence® (epirubicin), Navelbine® (vinorelbine)

(PRN) - Faropenem Phase III Clinical Trial Stopped to Consider ...  -  Dec 26, 2006
Bolsamania.com,...(PRN) - ADVENTRX Cleared to Initiate Vinorelbine Emulsion Bioequivalence Study ... [+]. (PRN) - pardonMOI Releases Its First Annual Top Ten List for

ADVENTRX Cleared to Initiate Vinorelbine Emulsion Bioequivalence Study  -  26 Dec 2006
FinanzNachrichten.de,The study is a multicenter, open-label, randomized crossover comparison of ANX-530 and the approved reference product Navelbine(R) (vinorelbine tartrate) in

(PRN) - David Coulter Settles Lawsuit Against Win Win Gaming, Inc ...  -  26 Dec 2006
Bolsamania.com,...(PRN) - ADVENTRX Cleared to Initiate Vinorelbine Emulsion Bioequivalence Study ... [+]. (PRN) - pardonMOI Releases Its First Annual Top Ten List for

Sonogram Results Can Help Direct Additional Treatment in Women ...  -  Dec 19, 2006
DG NewsThe 627 low chemosensitive women went on to receive an additional 4 cycles of TAC or 4 cycles of vinorelbine/capecitabine while the 1390 highly

Capecitabine Plus Bevacizumab Combination May Produce Clinical ...  -  Dec 20, 2006
DG NewsClinical investigators chose whether the patient received paclitaxel or vinorelbine. In an interim study analysis of 103 patients from a total of 109

Additional Chemotherapy May Improve Survival for Some Patients ...  -  Dec 18, 2006
Cancer Consultants (press release),48 patients who were all initially treated with the chemotherapy drugs Platinol® (cisplatin), Ellence® (epirubicin), and Navelbine® (vinorelbine).

Kosan's Hsp90 Inhibitor, Tanespimycin, Shows Promising Antitumor ...  -  Dec 14, 2006
PR Newswire (press release),One patient with documented progressive disease in the liver prior to study while being treated with trastuzumab/vinorelbine had a confirmed partial

ADVENTRX Announces 2006 Third Quarter Financial Results  09 Nov 2006
...trial in refractory breast cancer and to file an investigational new drug application for a bioequivalency clinical trial for ANX-530, vinorelbine emulsion, in ... -Yahoo! News (press release) Novacea to Hold Conference Call Regarding Oral Vinorelbine Program  Oct 31, 2006
Novacea, Inc. (NASDAQ: NOVC) will hold a conference call to provide an update on the company's oral vinorelbine program. This conference ... -Market Wire (press release) Novacea Drops Vinorelbine To Focus On Other Cancer Drugs  Nov 1, 2006
...is shaking up its pipeline by abandoning oral vinorelbine (OV) in the face of higher-than-expected development costs, and it will instead focus on Asentar (DN ... -Therapeutics Daily (subscription) (press release), Adjuvant Platinol®/Navelbine® Improves Survival in NSCLC  Oct 11, 2006
Researchers affiliated with the Late Adjuvant Cisplatin Evaluation (LACE vinorelbine project) have reported that adjuvant Platinol® (cisplatin) plus Navelbine ... -Cancer Consultants (press release), INEX Releases Third Quarter 2006 Operating Results  Nov 2, 2006
...the first patient in a phase 1 human clinical trial evaluating the safety, tolerability and preliminary efficacy of INX-0125 (sphingosomal vinorelbine) as a ... -Yahoo! News (press release) Hana Biosciences Announces Third Quarter 2006 Results  Nov 2, 2006
Key Achievements in Third Quarter 2006 -- Initiated a Phase I clinical study of Alocrest(tm) (vinorelbine tartrate liposomes injection) in patients with ... -PrimeZone (press release), Platinol®/Navelbine® Improves Survival in Lung Cancer  Oct 9, 2006
Society for Medical Oncology (ESMO), the chemotherapy combination consisting of Platinol® (cisplatin) plus Navelbine® (vinorelbine) improves survival among ... -Cancer Consultants (press release), Market Report -- In Play (WIRES)  Nov 1, 2006
...and that it has notified Pierre Fabre Medicament, SA of its decision to return the US and Canadian development and commercialization rights of vinorelbine oral ... -MSN Money Novacea's Phase 1 Data of Asentar Published in the Journal of ...  Oct 30, 2006
Novacea's second product candidate, oral vinorelbine, is expected to enter a registration trial for metastatic breast cancer in the second half of 2006. ... -Market Wire (press release) Diatos Strengthens Management Team with the Appointment of New ...  Oct 9, 2006
France) in a similar position with full responsibility for the corporate clinical development and implementation of Navelbine ® (vinorelbine) worldwide. ... -Business Wire (press release), Improved Progression-Free Survival in Advanced Breast Cancer with ...  Oct 13, 2006
...expressing HER-2. Herceptin is usually combined with chemotherapeutic agents such as Taxol® (paclitaxel), Taxotere® (docetaxel), and Navelbine® (vinorelbine ... -Cancer Consultants (press release), Brain metastases responded to vinorelbine combined with protracted ...  Sep 11, 2006
2006 SEP 11 - (NewsRx.com) -- Recurrent brain metastases (BM) responded to vinorelbine combined with a protracted course of temozolomide (TMZ), warranting a ... -Therapeutics Daily (subscription)

European Society for Medical Oncology - Press Program for the 31st ...  Sep 21, 2006
Lung Cancer In Lung Cancer, Cisplatin Plus Vinorelbine Offers Major Survival Benefits For lung cancer patients who have undergone a complete lung resection ... -PR Newswire

Lung cancer patients pretreated with taxane-based regimen managed ...  Sep 12, 2006
2006 SEP 12 - (NewsRx.com) -- Non-small cell lung cancer (NSCLC) patients pretreated with a taxane-based regimen could be treated with vinorelbine and cisplatin ... -Therapeutics Daily (subscription)

British Journal of Haematology Publishes Thrombosis Findings From ...  Sep 20, 2006
Novacea's second product candidate, oral vinorelbine, is expected to enter a registration trial for metastatic breast cancer in the second half of 2006. ... -Market Wire

Addition of Gemzar® to Paraplatin® Improves Progression-Free ...  Sep 20, 2006
...treatment of recurrent ovarian cancer including: Doxil® (pegylated doxorubicin), Thalomid® (thalidomide), Hycamptin® (topotecan) and Navelbine® (vinorelbine ... -Cancer Consultants

Mayne Pharma posts net loss of $31.34m  Sep 10, 2006
The company expects to take advantage of that with newly-launched products, including vinorelbine, bowel cancer treatment oxaliplatin, ondansetron and the ... -The Age

Mayne Pharma posts annual net loss  Sep 10, 2006
The pharmaceutical maker expects to take advantage of that capability with newly-launched products including vinorelbine, oxaliplatin, ondansetron and the ... -The Age

Recent findings in lung cancer described by researchers from Spain ...  Aug 29, 2006
Study 1: Lung cancer treated by biweekly regimen of cisplatin, gemcitabine and vinorelbine resulted in a high rate of response and comparatively low toxicity ... -Therapeutics Daily (subscription)

Trastuzumab Effective in Some Breast Tumors With Undetectable HER ...  Sep 5, 2006
Trastuzumab is known to act synergistically with cisplatin and other agents such as docetaxel, paclitaxel and vinorelbine against HER-2-positive breast cancers ... -Cancerpage.com

Final Results of Adjuvant Chemotherapy Versus Observation for ...  Aug 28, 2006
Trialist Association (ANITA) have published the final results of a randomized trial evaluating adjuvant Navelbine® (vinorelbine)/Platinol® (cisplatin) have ... -Cancer Consultants

Commencement of INX-0125 Phase 1 Clinical Trial Triggers US$1.0 ...  Aug 30, 2006
...the first patient in a Phase 1 human clinical trial evaluating the safety, tolerability and preliminary efficacy of INX-0125 (sphingosomal vinorelbine) as a ... -Yahoo! News

Novacea Reports Third Quarter 2006 Financial Results  -  Nov 13, 2006
Genetic Engineering News (press release),..."Most recently, we realigned our product portfolio with our decision to return North American development and commercialization rights for vinorelbine oral

Studies Show Preferential Effect of Paclitaxel Poliglumex in ...  -  Nov 15, 2006
DG News...every 3 weeks; or gemcitabine 1000 mg/m 2 on days 1, 8, 15, every 4 weeks; or vinorelbine 30 mg/m 2 on days 1, 8, 15, every 3 weeks.

Research from France, Spain and Japan in lung cancer provides new ...  Jun 27, 2006
Study 1: Lung cancer could be treated with gemcitabine plus vinorelbine. According to recent research from France, "In this phase ... -Therapeutics Daily (subscription)

Inex Revises Plan of Arrangement to Spin Out Tekmira ...  Jul 11, 2006
The three products in the Targeted Chemotherapy pipeline, Marqibo, INX-0125 (sphingosomal vinorelbine) and INX-0076 (sphingosomal topotecan), have been ... -Yahoo! News



Hana Biosciences Completes Licensing of Three Targeted Cancer Drug ...  May 8, 2006
...-- Sphingosome Encapsulated Vinorelbine Targeted to Start Clinical Trials in 2006, and Sphingosome Encapsulated Topotecan in 2007. ... - Genetic Engineering News

ADVENTRX Announces 2006 First Quarter Financial Results  May 10, 2006
...preclinical results were presented at the annual AACR meeting showing reduced vein toxicity, edema and erythema from our novel vinorelbine emulsion drug (ANX ... - Yahoo! News

Findings from Greece, the United Kingdom and Tokyo in breast ...  May 3, 2006
Study 1: Metastatic breast cancer (MBC) could be treated by gemcitabine in combination with vinorelbine. Researchers in Greece conducted ... - Therapeutics Daily (subscription)

ADVENTRX ANNOUNCES CLOSING OF MERGER WITH SD PHARMACEUTICALS  May 1, 2006
These candidates include SDP-012 (ANX-530, vinorelbine emulsion), which was the subject of a prior license agreement between the companies, announced in ... - Small Times

Inex Pharmaceuticals Closes Hana Biosciences Licensing Agreement  May 8, 2006
INEX has granted Hana a worldwide license to develop and commercialize Marqibo(TM) (sphingosomal vincristine), INX-0125 (sphingosomal vinorelbine) and INX-0076 ... - Yahoo! News

Novacea Announces Initial Public Offering  May 10, 2006
The company has one product candidate, DN-101, which is in a Phase 3 clinical trial for prostate cancer and a second product candidate, vinorelbine oral, which ... - Market Wire

Hana acquires anticancer compounds from Inex  May 8, 2006
The licensed products include Marqibo, a sphingosome encapsulated vinorelbine that has shown promising results in patients with non-Hodgkin's lymphoma and ... - Pharmaceutical Business Review

Hana Biosciences Reports First Quarter 2006 Results  May 4, 2006
The three candidates are known as Marqibo(R) (vincristine sulfate) Liposomes Injection, Vinorelbine Liposomes Injection, and Topotecan Liposomes Injection. ... - Genetic Engineering News

Sequential Two-Drug Combinations Explored in Advanced NSCLC  Apr 20, 2006
...phase II clinical trial conducted in Greece, treatment of stage IIIB or stage IV non-small cell lung cancer (NSCLC) with Navelbine® (vinorelbine) and Platinol ... - Cancer Consultants

Herceptin® May Change the Natural History of Patients with HER2 ...  May 1, 2006
Italian researchers have reported that patients with HER2-positive breast cancer treated with Herceptin (trastuzumab) and Navelbine® (vinorelbine) have better ... - Cancer Consultants

Additional Evidence that Herceptin® Benefits Women with HER2 ...  Apr 17, 2006
...conducted in Italy, women with metastatic HER2-positive breast cancer who were treated with Herceptin® (trastuzumab) and Navelbine® (vinorelbine) had better ... - Cancer Consultants





Adjuvant Docetaxel or Vinorelbine with or without Trastuzumab for ...  Feb 22, 2006
Background We compared docetaxel with vinorelbine for the adjuvant treatment of early breast cancer. Women with tumors that overexpressed ... - New England Journal of Medicine (subscription),

Breast Cancer Drugs Limit Post-Surgery Recurrence  Feb 22, 2006
22 (HealthDay News) -- A new head-to-head study finds the chemotherapy drug docetaxel (Taxotere) beating another, vinorelbine (Navelbine), in helping extend ... - Forbes

Trails to detect effective breast cancer drugs that reduces ...  Feb 23, 2006
...cancer surgery. The chemotherapy drugs docetaxel (Taxotere) and vinorelbine (Navelbine) are tested to analyze the outcomes. It was ... - MedIndia,

Nitroglycerin May Enhance Chemotherapy for Non-Small Cell Lung ...  Feb 6, 2006
Researchers from Japan have reported that the use of nitroglycerin combined with the chemotherapy drugs Navelbine® (vinorelbine) and Platinol® (cisplatin ... - Cancer Consultants,

Optimising Herceptin-based Therapy in HER2-positive Metastatic ...  Feb 22, 2006
Other researchers are also evaluating combinations of trastuzumab and other chemotherapy schedules, including trastuzumab/vinorelbine, which was highly active ... - DG News

Options Expanding With First-line Capecitabine (Xeloda) ...  Feb 22, 2006
One such is capecitabine/vinorelbine (XN), which has been tested as either first- or second-line treatment over a range of trials of metastatic breast cancer. ... - DG News

Novacea Files for Initial Public Offering  Feb 10, 2006
The Company has one product candidate, DN-101, which is in a Phase 3 clinical trial for prostate cancer and a second product candidate, vinorelbine oral, which ... - Market Wire

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