Recent news on Viracept

HIV resistance mutations common but CXCR4 rare among untreated US ...  -  May 22, 2007
Aidsmap,Resistance to nevirapine (Viramune), delavirdine (Rescriptor), stavudine (Zerit), efavirenz (Sustiva), zidovudine (Retrovir), and nelfinavir (Viracept) were

Breaking Merck patent may drive investment away from Brazil  -  May 9, 2007
Pharmaceutical Business ReviewThe same happened with Gilead's Viread (tenofovir), a high-selling NRTI and Roche/Pfizer's Viracept (nelfinavir), a PI that has been facing decreasing sales

No major metabolic differences between PI-based and NNRTI-based ...  -  Apr 29, 2007
Aidsmap,The treatments reflect what was in use during that period: nelfinavir (Viracept) was the most commonly used PI (61%), followed by ritonavir-boosted PIs

Some HIV Drugs May Up Heart Risk  -  Apr 25, 2007
WebMDExamples of some protease inhibitors are Crixivan, Norvir, Viracept, Agenerase, and Kaletra. Other HIV drugs called nonnucleoside reverse-transcriptase

Some HIV Drugs May Up Heart Risk  -  26 Apr 2007
WebMDExamples of some protease inhibitors are Crixivan, Norvir, Viracept, Agenerase, and Kaletra. Other HIV drugs called nonnucleoside reverse-transcriptase

Expecting Trimeris To Fall Following HIV Drug Development  -  Apr 10, 2007
Seeking Alpha,Firm discusses BMY's Zerit and PFE's Viracept as case studies, both lost significant market share. If Fuzeon suffered a similar rate of market share decline

Use of computer-assisted drug design in drug discovery  -  Apr 15, 2007
News-Medical.net,In 1995, Agouron Pharmaceuticals obtained FDA approval for Viracept to treat AIDS patients as part of a "cocktail" of drugs.

AIDS Group Bans Pfizer Sales Reps  -  Feb 8, 2007
Forbes,Pfizer also sells the HIV drugs Viracept and Rescriptor. The company, which didn't break out sales of the drugs in their most recent quarterly report,

Company Profile for TRACON Pharmaceuticals, Inc.  -  Feb 9, 2007
Business Wire (press release),The management team has led or contributed to the development of six approved biopharmaceuticals: Rituxan®, Zevalin®, Viracept®, Targretin®, Macugen® and

Company Profile for Tracon Pharmaceuticals, Inc.  -  Feb 9, 2007
PharmaLive.com (press release),The management team has led or contributed to the development of six approved biopharmaceuticals: Rituxan(R), Zevalin(R), Viracept(R), Targretin(R),

National business briefs  -  Feb 9, 2007
NorthJersey.com,Pfizer, the world's largest drug maker, sells two HIV products, Rescriptor and Viracept, and is seeking US regulatory approval for a third.

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,Roche's Invirase/Fortovase (saquinavir), Abbott Laboratories Norvir (ritonavir), Merck & Co's Crixivan (indinavir) and Pfizer's Viracept (nelfinavir).

Zacks Analyst Blog Highlights: Vertex Pharmaceuticals ...  -  Feb 6, 2007
Business Wire (press release),...has a convenient dosing and favorable metabolic profile relative to first-generation protease inhibitors such as Agenerase, Crixivan, and Viracept.

Pediatric studies lead to more information on drug labels  -  Feb 1, 2007
AAP News (subscription)Viracept (nelfinavir) is a protease inhibitor that can be used in combination therapy for the treatment of HIV infection. Nelfinavir was the most frequently

Be careful if using fosamprenavir/ritonavir for PEP, and did HCV ...  -  Jan 31, 2007
Aidsmap,Until January 2006 doctors in Lille prescribed a PEP regimen consisting of AZT/3TC (Combivir) with the protease inhibitor, nelfinavir (Viracept).

Company Announces Acquisition of Research and Development Programs ...  -  Dec 26, 2006
Drug Newswire (press release),Dr. Quart joined Agouron in 1993 and was instrumental in the development and registration of nelfinavir (Viracept(R)), which went from the lab bench to NDA

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan Invirase). Only one person had used amprenavir (Agenerase), none had used any of

Company Announces Acquisition of Research and Development Programs ...  -  26 Dec 2006
Drug Newswire (press release),Dr. Quart joined Agouron in 1993 and was instrumental in the development and registration of nelfinavir (Viracept(R)), which went from the lab bench to NDA ...

Emergence of resistance mutations: a comparison between drug ...  -  Dec 19, 2006
Aidsmap,...study is limited by “the retrospective and potentially biased case selection.� Also, most of the PIs used were nelfinavir (Viracept), indinavir (Crixivan ...

Roche Diagnostics Will Mark World AIDS Day  -  Dec 1, 2006
Inside INdiana Business (press release),Roche makes its HIV protease inhibitors – Invirase (saquinavir) and Viracept (nelfinavir) available at no profit prices for direct supplies from Roche Basel ...

Roche - Initiatives in HIV/AIDS  -  Dec 4, 2006
PharmaLive.com (press release),Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan Africa ...

Kaletra not associated with raised blood pressure, manufacturer ...  Oct 30, 2006
Kaletra (lopinavir/ritonavir) are no more likely to develop high blood pressure than those taking another protease inhibitor nelfinavir (Viracept) or the NNRTI ... -Aidsmap, Appointment of VP Program Planning and Management  Nov 1, 2006
...involved in the development and registration of three products in his career, including both formulation and regulatory CMC work on Viracept® while at Agouron ... -Yahoo! News (press release) Antiretroviral Drugs: A Shot in the Arm to Fight Malaria?  Oct 12, 2006
The presence of nelfinavir (Viracept), amprenavir (Agenerase) and the NNRTI nevirapine (Viramune) in thereapies did not hamper the proliferation of the ... -MedIndia, ARV drugs may also help fight malaria  Oct 10, 2006
Therapies which included nelfinavir (Viracept), amprenavir (Agenerase) and the NNRTI nevirapine (Viramune) did not inhibit the growth of the malaria parasite. ... -SABC News, First Technology Transfers from Roche to enable local production ...  Sep 22, 2006
Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan Africa ... -PharmaLive.com

Pfizer, Firm Partner in Fungal Treatment  Aug 26, 2006
...owner. In the United States, Pfizer donates Diflucan and its antiretroviral Viracept to low-income, uninsured patients. Outside ... -This Day (subscription)

Roche - Initiatives in HIV/AIDS  -  Dec 4, 2006
PharmaLive.com (press release),Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan

Roche Diagnostics Will Mark World AIDS Day  -  Dec 1, 2006
Inside INdiana Business (press release),Roche makes its HIV protease inhibitors – Invirase (saquinavir) and Viracept (nelfinavir) available at no profit prices for direct supplies from Roche Basel

IAC: Long-Term Therapy with Antiretrovirals Tolerated by Children  Aug 16, 2006
The protease inhibitors used at the hospital included Norvir (ritonavir), approved in 1996; Viracept (nelfinavir), approved in 1997; and Kaletra (lopinavir ... -MedPage Today

Pfizer, Firm Partner in Fungal Treatment  Aug 26, 2006
...owner. In the United States, Pfizer donates Diflucan and its antiretroviral Viracept to low-income, uninsured patients. Outside ... -This Day (subscription)

AIDS Drugs, Prices Cut 90%, Remain Out of Reach for Neediest  Aug 13, 2006
At 60 cents a pill, Roche's Viracept costs about twice as much in such countries as it does in the poorest nations. The company ... -Bloomberg

Large analysis shows benefits of starting treatment with efavirenz  Aug 22, 2006
In contrast, patients starting with nelfinavir (Viracept), unboosted saquinavir, unboosted indinavir or abacavir (Ziagen) had a similar risk of AIDS or death ... -Aidsmap

Abacavir/3TC backbone proves most durable for children over five ...  Aug 16, 2006
Children who had symptoms of HIV infection took their allotted treatment with the protease inhibitor (Viracept), but the minority of children participating in ... -Aidsmap

WHO issues paediatric HIV treatment guidelines for low-income ...  Aug 8, 2006
...abacavir unless abacavir was used in first-line treatment, plus either lopinavir/ritonavir (Kaletra), saquinavir/ritonavir (Invirase) or nelfinavir (Viracept). ... -Aidsmap

Nevirapine-based triple-drug combinations safe for use in pregnant ...  Jul 10, 2006
Only ten of the 46 women with severe toxicity needed to change treatment, replacing nevirapine with either nelfinavir (Viracept) or indinavir (Crixivan). ... -Aidsmap

Clinical Pharmacology of Antiretroviral Therapy -- New Data for ...  Jun 22, 2006
The PIs saquinavir (Invirase, Roche), nelfinavir (Viracept, Agouron Pharmaceuticals), ritonavir (Norvir, Abbott), lopinavir, and atazanavir (Reyataz, Bristol ... -Medscape (subscription)



AnnKatrin Petersen, MD Joins MIGENIX as VP Clinical Development  May 1, 2006
Most recently at Pfizer she was responsible for the clinical development of Viracept (nelfinavir mesylate) for the treatment of HIV infection, including filing ... - Yahoo! News





Needle highlights danger of job  11 Apr 2006
Combivir is often taken in tandem with the drug Viracept in a regimen known as HIV post-exposure prophylaxis, which is intended to reduce the risk of HIV ... - MetroWest Daily News

Wide variability in drug levels casts doubt on the practicality of ...  Mar 28, 2006
The two taking nelfinavir (Viracept) had ICVs of 30 and 39% for nelfinavir and of 44 and 54% for nelfinavir’s active metabolite M8. ... - Aidsmap

ABBOTT STATEMENT ON ADVANCING PEDIATRIC HIV TREATMENT IN ...  Mar 13, 2006
Once-daily lopinavir/ritonavir should not be taken with Agenerase(R), Sustiva(R), Viracept(R), Viramune(R), Dilantin(R), Phenobarbital or Tegretol(R). ... - ITNews

Abbott Statement on Advancing Pediatric HIV Treatment in ...  Mar 13, 2006
Once- daily lopinavir/ritonavir should not be taken with Agenerase®, Sustiva®, Viracept®, Viramune®, Dilantin®, Phenobarbital or Tegretol®. ... - Yahoo! News



Restoration of CD4 T-cells limited in children starting HIV ...  Mar 2, 2006
...lamivudine, Epivir). The protease inhibitors taken by most children were nelfinavir (Viracept) and ritonavir (Norvir). Although ... - Aidsmap,

Holding on to Hope  Feb 23, 2006
A few weeks later, she visited an infectious disease specialist who put her on 10 Viracept and two Comivir a day, telling her the cocktail should keep her ... - ASU Web Devil,

How much is a cure gonna cost?  Feb 7, 2006
Some medicines, like Viracept, can cost up to $700 a month for consumers who depend on them to maintain a healthy outlook on their lives. ... - The Southern Digest,

Multi-component drug delivery system: An emerging trend  Feb 8, 2006
Protease Inhibitors (PIs), which include amprenavir (Agenerase), nelfinavir (Viracept), saquinavir (Fortavase), indinavir (Crixivan), ritonavir (Norvir ... - Express Pharma Pulse

Merck, Gilead Drugs Offer New Approach to Tackle HIV Resistance  Feb 6, 2006
GlaxoSmithKline's Lexiva and Pfizer Inc.'s Viracept interfere with the action of the protease enzyme and drugs, including Gilead's Viread, inactivate another ... - Bloomberg

How much is a cure gonna cost?  Feb 7, 2006
Some medicines, like Viracept, can cost up to $700 a month for consumers who depend on them to maintain a healthy outlook on their lives. ... - The Southern Digest

Most people given non-occupational PEP fully adhere to their ...  Jan 19, 2006
In 127 cases, triple antiretroviral therapy consisting of AZT (zidovudine, Retrovir), 3TC (lamivudine, Epivir) and nelfinavir (Viracept) was provided, with the ... - Aidsmap

Roche offers help to local manufacturers to produce HIV medicine ...  Jan 12, 2006
Roche makes its HIV protease inhibitors Invirase and Viracept available at no profit prices for direct supplies from Roche Basel to LDCs and sub-Saharan Africa ... - SocialFunds.com

Roche offers HIV drug expertise to poor nations  Jan 12, 2006
Roche said it would make its HIV protease inhibitors Invirase and Viracept available at no-profit prices for direct supplies from Roche Basel to LDCs and sub ... - MedIndia

HIV Drug Resistance Linked to Viral Fitness  Jan 12, 2006
...of data on individual pharmacokinetic differences. Also, there was only one candidate protease inhibitor, Viracept (nelfinavir). - MedPage Today

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