Recent news on Zerit

Mitochondrial toxicity can be increased by genetic factors  -  May 14, 2007
Aidsmap,A new gene mutation linked to the side effect has been identified in a Thai woman treated with stavudine (Zerit) for a year.

International panel issues new HIV/HCV co-infection guidelines  -  May 24, 2007
Aidsmap,Certain nucleoside analogues, notably ddI and d4T (Zerit), can cause mitochondrial toxicity (which can lead to liver steatosis), nevirapine (Viramune) can

HIV resistance mutations common but CXCR4 rare among untreated US ...  -  May 22, 2007
Aidsmap,Resistance to nevirapine (Viramune), delavirdine (Rescriptor), stavudine (Zerit), efavirenz (Sustiva), zidovudine (Retrovir), and nelfinavir (Viracept) were

No major metabolic differences between PI-based and NNRTI-based ...  -  Apr 29, 2007
Aidsmap,...d4T (Zerit, stavudine) was also in common use, in about 36% of all participants. Treatment switching was also fairly common: 51%, 38% and 78% of people in

Tentative approval of generic stavudine  -  Apr 24, 2007
PharmaLive.com (press release),This is a generic formulation of the already approved Zerit brand capsules, 30 mg and 40 mg, made by Bristol Myers Squibb, which is protected by existing

Students Protest High-Priced Pills  -  Apr 19, 2007
Hartford Courant,Public pressure led the company to slash the price of Zerit and allow generic copies to be made. The victory led to the creation of a national advocacy

Expecting Trimeris To Fall Following HIV Drug Development  -  Apr 10, 2007
Seeking Alpha,Firm discusses BMY's Zerit and PFE's Viracept as case studies, both lost significant market share. If Fuzeon suffered a similar rate of market share decline

The Top 14 Most Counterfeited Medications  -  Mar 28, 2007
ScienceBlogsZerit (stavudine - used in the treatment of HIV). 14. Zyprexa (olanzapine - used in the treatment of psychiatric conditions including bipolar mania and

Yale students work to make drugs affordable  -  Apr 18, 2007
New Haven Register (subscription),Bristol-Myers Squibb and Yale University to pledge not to enforce the patent in South Africa on d4T or Zerit, an important part of the HIV treatment.

d4T dose can be reduced without loss of effectiveness, meta ...  -  Apr 2, 2007
Aidsmap,...company was investing in an extended release, once daily formulation of d4T called Zerit XR that was intended to extend the patent life of the product.

CROI: high burden of side-effects from d4T leads to WHO dose ...  -  Mar 21, 2007
Aidsmap,The World Health Organization’s HIV treatment guidelines panel has concluded that the recommended adult dose of d4T (stavudine, Zerit) should be reduced to

Not so happy feet  -  Mar 21, 2007
NAPWA,The so-called ‘D’ drugs – ddI (didanosine/Videx), ddC (zalcitabine/Hivid) and d4T (stavudine/Zerit) have long been strongly associated with the development

CROI: Is there a ceiling to CD4 recovery on virologically ...  -  Mar 13, 2007
Aidsmap,Those on any combination containing tenofovir (Viread) (average 39 to 44 cells/mm 3 /year less compared to stavudine (Zerit), p = 0.015).

CROI: Remission of Kaposi's sarcoma seen in rural Uganda when HIV ...  -  Mar 12, 2007
Aidsmap,The primary ART regimen was 3TC (lamivudine, Epivir), d4T (stavudine, Zerit), and nevirapine (Viramune). KS was diagnosed based on clinical grounds

Women experience rapid fall in genital secretion of HIV after ...  -  Feb 19, 2007
Aidsmap,...cells/mm 3 and were provided with an antiretroviral regimen consisting of 3TC (lamivudine, Epivir), d4T (stavudine, Zerit) and nevirapine (Viramune).

Use of d4T is associated with buffalo hump  -  Feb 2, 2007
Aidsmap,...has a significant association with the use of d4T (stavudine, Zerit), and with fat loss - a side-effect that has long been associated with d4T.

Suspects names in fatal shooting of store clerk  -  18 Jan 2007
Atlanta Journal Constitution (subscription),Zerit Haileslasie, 39, of Lilburn was shot several times, at least once in the head, Atlanta police spokesman Joe Cobb said. Haileslasie later died at Grady

Company Announces Acquisition of Research and Development Programs ...  -  18 Jan 2007
Yahoo! News (press release)...and registration of important drugs for the treatment of HIV and Cancer, including paclitaxel (Taxol®), didanosine (Videx®), and stavudine (Zerit®).

Rally For Missing Soldiers  -  Jan 15, 2007
Totally Jewish,At the end of the rally in Zerit, dozens of Eldad and Ehud's relatives, comrades and other citizens continued towards the point from which they were

Suspected gunman in clerk’s shooting arrested  -  Jan 16, 2007
Atlanta Journal Constitution (subscription),Zerit Haileslasie, 39, was shot several times during a robbery at the Shell station at 3195 Donald Lee Hollowell Parkway.

Clerk killed in convenience store robbery  -  Dec 20, 2006
Atlanta Journal Constitution (subscription),A third suspect allegedly went behind the counter at the Shell Station in the 3100 block of Donald Lee Hollowell Parkway near I-285 and shot Zerit

The ones HIV left in limbo  -  Jan 17, 2007
Los Angeles Times,Kaletra (three capsules twice a day; another protease inhibitor); Viread, Epzicom and Zerit (one pill a day each to interfere with the virus' ability to

Company Announces Acquisition of Research and Development Programs ...  -  Jan 16, 2007
Drug Newswire (press release),...registration of important drugs for the treatment of HIV and Cancer, including paclitaxel (Taxol(R)), didanosine (Videx(R)), and stavudine (Zerit(R)).

Emergence of resistance mutations: a comparison between drug classes  -  Jan 17, 2007
Aidsmap,...more quickly than resistance mutations to the nucleosides known as “thymidine analogues� – zidovudine (AZT, Retrovir) and stavudine (d4T, Zerit).

Company Announces Acquisition of Research and Development Programs ...  -  26 Dec 2006
Drug Newswire (press release),...registration of important drugs for the treatment of HIV and Cancer, including paclitaxel (Taxol(R)), didanosine (Videx(R)), and stavudine (Zerit(R)).

Suspected gunman in clerk’s shooting arrested  -  Dec 22, 2006
Atlanta Journal Constitution (subscription),Zerit Haileslasie, 39, was shot several times during a robbery at the Shell station at 3195 Donald Lee Hollowell Parkway.

Suspects names in fatal shooting of store clerk  -  Dec 21, 2006
Atlanta Journal Constitution (subscription),Zerit Haileslasie, 39, of Lilburn was shot several times, at least once in the head, Atlanta police spokesman Joe Cobb said. Haileslasie later died at Grady

Clerk killed in convenience store robbery  -  Dec 20, 2006
Atlanta Journal Constitution (subscription),A third suspect allegedly went behind the counter at the Shell Station in the 3100 block of Donald Lee Hollowell Parkway near I-285 and shot Zerit

Ethics and Patents  -  Dec 5, 2006
Inside Higher Ed,Most of Yale’s 311 patents cover pharmaceutical inventions and one of the most profitable was Zerit, one of the main drugs used in the AIDS cocktail.

Company Announces Acquisition of Research and Development Programs ...  -  Dec 22, 2006
Yahoo! News (press release)...and registration of important drugs for the treatment of HIV and Cancer, including paclitaxel (Taxol®), didanosine (Videx®), and stavudine (Zerit®).

Levin has role in solving AIDS crisis  -  Dec 6, 2006
Yale Daily News,This decision lowered the cost of Zerit from $1600 to $55 per patient per year and made the drug significantly more accessible to AIDS victims in the

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,...more quickly than resistance mutations to the nucleosides known as “thymidine analogues� – zidovudine (AZT, Retrovir) and stavudine (d4T, Zerit).

Univ. not to patent chemical  -  Dec 4, 2006
Yale Daily News,In 2001, Yale made the unusual decision to cut the cost of Zerit - one of the main components of an AIDS cocktail that was discovered at Yale - in South

Biotech survives Science Park  -  Dec 9, 2006
The Yale Herald,In 2000, Yale sold only a portion of its royalties from Zerit, a Bristol-Myers Squibb AIDS drug based on the research of two Yale professors,

Aurobindo gets MCC nod for ARV drug  Nov 6, 2006
...nucleoside analog class (NRTIused in combination with other NRTIs and non-NRTIs class of of drugs in HIV patients.Its international brand name is Zerit and is ... -Andhra Cafe, Bristol-Myers Squibb Company Reports Financial Results for the ...  Oct 26, 2006
Monopril 34 49 (31)% - 1 (100)% (54)% Virology Reyataz 233 176 32% 129 105 23% 15% Sustiva franchise (total revenue) 201 170 18% 128 101 27% 12% Zerit 38 51 (25 ... -PR Newswire (press release), Speaking of generics  Oct 25, 2006
Trusopt, Oct. 2008. Valtrex, Dec. 2009. Vexol, Jan. 2009. Xenical, Dec. 2009. Zerit, Dec. 2008. Zofran, Dec. 24, 2006. Zymar, June 2008. Zyrtec, Dec. 2007. ... -Monterey County Herald, Recombinant human growth hormone reduces visceral fat in two ...  Sep 19, 2006
...drugs is less well understood than is the case for subcutaneous fat loss (lipoatrophy), which has been strongly associated with d4T (stavudine, Zerit) and to a ... -Aidsmap

FDA Announces Tentative Approval of Generic Stavudine Capsules  Aug 30, 2006
This product is a generic version of Zerit Capsules, 30 mg and 40 mg, a nucleoside reverse transcriptase inhibitor (NRTI) used in combination with other ... -PharmaLive.com

Ethics and Patents  -  Dec 5, 2006
Inside Higher Ed,Most of Yale’s 311 patents cover pharmaceutical inventions and one of the most profitable was Zerit, one of the main drugs used in the AIDS cocktail.

A New Deal On Lifesaving Drugs  -  Nov 13, 2006
Harvard Crimson,Yale licensed an exclusive patent for the drug to pharmaceutical giant Bristol-Myers Squibb, which then marketed it under the brand name Zerit.

The World in Brief  -  Nov 20, 2006
UNI Northern Iowan,...after students at Yale in 2001 objected to the university’s license to Bristol-Myers Squibb Co. for a Yale-invented AIDS drug, since marketed as Zerit.

Levin has role in solving AIDS crisis  -  Dec 6, 2006
Yale Daily News,This decision lowered the cost of Zerit from $1600 to $55 per patient per year and made the drug significantly more accessible to AIDS victims in the

Biotech survives Science Park  -  Dec 9, 2006
The Yale Herald,In 2000, Yale sold only a portion of its royalties from Zerit, a Bristol-Myers Squibb AIDS drug based on the research of two Yale professors,

Univ. not to patent chemical  -  Dec 4, 2006
Yale Daily News,In 2001, Yale made the unusual decision to cut the cost of Zerit - one of the main components of an AIDS cocktail that was discovered at Yale - in South

Stavudine, didanosine and AZT pose diabetes risk in D:A:D study  -  Nov 20, 2006
Aidsmap,Stavudine (d4T, Zerit) was by some way the drug most strongly associated with developing diabetes with an increased risk of 19% for every year spent on d4T,

South Africa: Govt Aids Programme On Course But People Still Dying  -  Nov 14, 2006
AllAfrica.com,...by the buildup of lactic acid in the body) in patients using Stavudine (also known as Zerit or d4T), which is included in South Africa's free programme.

IAC: Clinicians Urged to Consider HIV's Long-Term Complications  Aug 22, 2006
Gilead Study 903 that compared two regimens for HIV treatment that differed only in that the nucleoside reverse transcriptase inhibitor Zerit (stavudine) was ... -MedPage Today

IAC: Micronutrients Improve Immune Function In HIV  Aug 15, 2006
To be eligible for the study, patients also had to be taking either Videx (didanosine) or Zerit (stavudine) and have had persistent peripheral neuropathy. ... -MedPage Today

Micronutrient supplement increases CD4 cell counts in patients on ...  Aug 24, 2006
All of the participants were taking antiretroviral therapy containing d4T (stavudine, Zerit) or ddI (didanosine, Videx / VidexEC), and had symptoms of ... -Aidsmap

Ranbaxy presents bioequivalence data on two paediatric fixed dose ...  Aug 16, 2006
...for children of varying ages, a recent Malawian study found that this practice may result in significant under dosing of stavudine (Zerit) and lamivudine ... -Aidsmap

Thailand `Confident' AIDS Infections Will Fall, Thaksin Says  Aug 18, 2006
...program has been successful because of a locally produced triple-drug combination of versions of Bristol-Myers Squibb Co.'s Zerit, GlaxoSmithKline Plc's Epivir ... -Bloomberg

Brain problems and peripheral neuropathy under-diagnosed in Asia ...  Aug 14, 2006
...patients were taking so-called “d� drugs from the nucleoside analogue (NRTI) class of anti-HIV drugs, with 37% taking either d4T (stavudine, Zerit) or ddI ... -Aidsmap

Efavirenz more durable than Kaletra over two years in treament ...  Aug 17, 2006
...in the triple-drug therapy groups also received 3TC (lamivudine, Epivir), plus their choice of AZT (zidovudine, Retrovir; 42%), d4T (stavudine, Zerit; 24%), or ... -Aidsmap

HIV infection: Atripla more effective and better tolerated than ...  Aug 7, 2006
JAMA ), which showed that Tenofovir DF was equally effective but had fewer side effects than another antiretroviral drug called Stavudine ( d4T, Zerit ). ... -Xagena.it

NRTI-sparing combination of ritonavir-boosted indinavir and ...  Aug 9, 2006
NRTIs, particularly d4T (stavudine, Zerit) and AZT (zidovudine, Retrovir) can cause loss of fat from under the skin or ‘lipoatrophy’. ... -Aidsmap

Bristol-Myers Squibb Company Reports Financial Results for the ...  Jul 27, 2006
55 50 10% 46 42 10% (21)% Monopril 49 54 (9)% 1 2 (50)% (54)% Virology Reyataz 236 183 29% 122 98 24% 18% Sustiva 193 167 16% 115 97 19% 7% Zerit 41 59 (31 ... -PR Newswire

Traditional risk factors and use of some anti-HIV drugs increase ...  Jul 21, 2006
...also found that the use of certain antiretroviral drugs was significantly associated with an increase in uric acid, including d4T (stavudine, Zerit, p < 0.001 ... -Aidsmap

A Quarter Century of Battling HIV/AIDS  Jul 21, 2006
In 1991, Bristol Myers Squibb came out with Videx, the second NRTI to be approved, and the company added another, Zerit, in 1994. ... -Drug Discovery & Development

HIV-positive patients with 'dead bone' usually have other risk ...  Jul 17, 2006
The antiretrovirals d4T (stavudine, Zerit) and ddI (Videx) which are known to cause mitochondrial toxicity, were used by 36 (76%) individuals. ... -Aidsmap

Aurobindo receives US FDA approval for Stavudine capsules  Jun 30, 2006
The international. brand name is Zerit and is marketed by Bristol Myers Squibb. Nucleoside analogs are thought to slow the progression of AIDS by inhibiting HIV ... -Moneycontrol.com

Fatty liver prevalence high with HIV/HCV coinfection: 'use ddI and ...  Jun 30, 2006
Individuals coinfected with HIV and hepatitis C virus (HCV) should use ddI (didanosine, Videx/Videx EC) and d4T (stavudine, Zerit) with caution, according to ... -Aidsmap

Pill for AIDS patients in poor countries wins US approval  Jul 6, 2006
Dybul said he was pleased that the new pill did not contain D4T, also known as stavudine and Zerit, which is another common first-line drug, but somewhat more ... -International Herald Tribune

Nevirapine-based triple-drug combinations safe for use in pregnant ...  Jul 10, 2006
...took AZT (zidovudine, Retrovir and 3TC (lamivudine, Epivir) with nevirapine, although those with low haemoglobin levels took d4T (stavudine, Zerit) in place of ... -Aidsmap

Hizbullah attack on northern border and IDF response  Jul 12, 2006
An IDF reconnaissance activity, conducted by two Hummer jeeps, was attacked close to the fence between Israel and Lebanon, in the area between Shtula and Zerit ... -Israel Ministry of Foreign Affairs

Aurobindo Pharma Receives Tentative FDA Approval To Produce Oral ...  Jul 3, 2006
...of India , 6/29). Stavudine is a generic form of Bristol-Myers Squibb's Zerit (Aurobindo release, 6/30). The tentative approval ... -Kaiser network.org

FDA List Serve - Tentative approval: generic stavudine 15 & 20 mg ...  Jun 28, 2006
21, 2006. This is a generic version of the already-approved Zerit brand of the product manufactured by Bristol Myers-Squibb. The ... -PharmaLive.com



Judge doubts victim story  Apr 20, 2006
Calgarian Solomon Zerit yesterday testified he could not say who slashed him with a double-bladed, S-shaped weapon which resembled something out of Star Trek. ... - Calgary Sun

Treatment simplification appears clinically safe in children with ...  May 11, 2006
The most commonly used nucleoside combinations were 3TC (lamivudine, Epivir) with AZT (zidovudine, Retrovir) or 3TC with d4T (stavudine, Zerit). ... - Aidsmap

HIV Pharmacology Workshop: Are drug levels affected by racial ...  Apr 30, 2006
...day (QD) plus two nucleoside reverse transcriptase inhibitors (NRTI) comprising 3TC (lamivudine, Epivir), ddI-EC (VidexEC)or d4T (stavudine, Zerit) to patients ... - Aidsmap

An industry in flux  Apr 21, 2006
...he oversaw the marketing efforts for several key oncology and immunology products, including the launches of the chemotherapy drug Taxol and the HIV drug Zerit ... - Med Ad News (subscription)

Bristol-Myers Squibb Company Reports First Quarter 2006 Financial ...  Apr 27, 2006
55 49 12% 47 42 12% (25)% Monopril 48 59 (19)% 2 3 (33)% (55)% Virology Reyataz 207 149 39% 119 92 29% 19% Sustiva 175 173 1% 108 103 5% 4% Zerit 40 59 (32 ... - Yahoo! News





Startup royalties boost science budget  Apr 4, 2006
...said. Zerit, a highly successful AIDS drug, is responsible for much of the last decade's profits, Deputy Provost Charles Long said. ... - Yale Daily News

Study finds no link between brain-penetrating antiretroviral drugs ...  Mar 21, 2006
Previous studies have shown that these are AZT (zidovudine, Retrovir), d4T (stavudine, Zerit), 3TC (lamivudine, Epivir), abacavir (Ziagen), nevirapine (Viramune ... - Aidsmap

Aids: Stocrin price cut to lead to more reductions  Mar 21, 2006
...three 200mg capsules. The drug is usually taken in combination with the drugs Zerit and Epivir to complete the cocktail. With the ... - East African

Initial Antiretroviral Treatment of HIV Infection  Mar 10, 2006
Association, which showed that tenofovir DF was equally effective but had fewer side effects than another antiretroviral drug called stavudine (d4T, Zerit). ... - eMaxHealth.com



Restoration of CD4 T-cells limited in children starting HIV ...  Mar 2, 2006
The majority (74%) of the children took two NRTIs alongside their protease inhibitor, the commonest being d4T (stavudine, Zerit) and 3TC (lamivudine, Epivir). ... - Aidsmap,

CytoDyn Gets Greenlight from Its Investigators for China Joint ...  Feb 27, 2006
Truvada® manufactured by Gilead (Nasdaq: GILD), Epzicom® and Lexiva® manufactured by GlaxoSmithKline (NYSE: GSK), and Reyataz® and Zerit® manufactured by ... - Financial News USA,

Insulin resistance common in HIV-positive children  Feb 6, 2006
...including exercise, healthy diets, and, possibly, avoidance of anti-HIV drugs linked to the syndrome, such as protease inhibitors and d4T (stavudine, Zerit). ... - Aidsmap,

CROI: Capsaicin patch helps relieve neuropathy  Feb 10, 2006
...both by HIV and by certain HIV medications, such as ddI (didanosine, Videx / VidexEC), ddC (zalcitabine, Hivid) and d4T (stavudine, Zerit), nicknamed the ‘d ... - Aidsmap,

CROI: Disappointment for glitazones, metformin and testosterone ...  Feb 10, 2006
...individuals on antiretrovirals are still being investigated, there is increasing agreement that the thymidine analogues, d4T (stavudine, Zerit) and AZT ... - Aidsmap,

CROI: Atazanavir and atazanavir/ritonavir safe and effective in ...  Feb 13, 2006
...once daily. All patients also received once-daily 3TC (lamivudine, Epivir) and extended-release d4T (stavudine, Zerit PRC). The ... - Aidsmap,

Multi-component drug delivery system: An emerging trend  Feb 8, 2006
3TC (Epivir), tenofovir (Viread), abacavir/lamivudine /zidovudine (Trizivir), lamivudine/zidovudine (Combivir), stavudine, d4T (Zerit), didanosine, ddI (Videx ... - Express Pharma Pulse,

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