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Recent news on Zidovudine


Zidovudine Syrup (Zidovudine capsule) Information  -  May 18, 2007
American Chronicle,Zidovudine medication belong to Antiretroviral/Nucleoside reverse transcriptase inhibitor class. Zidovudine inhibits replication of retroviruses including

Third Trimester Exposure To Anti-HIV Drugs Linked To Mitochondrial ...  -  May 2, 2007
Medi News Direct,The children with MD (cases) were more likely to be exposed in-utero to Lamivudine (3TC, odds ratio 3.76) or Zidovudine-Lamivudine combination (ZDV/3TC,

Medicare Issues Proposed Coverage Decision On Erythropoesis ...  -  May 23, 2007
Medical News Today (press release),...to reduce potential blood transfusions, and for the treatment of anemia due to zidovudine therapy in patients with human immunodeficiency virus (HIV).

HIV resistance mutations common but CXCR4 rare among untreated US ...  -  May 22, 2007
Aidsmap,Resistance to nevirapine (Viramune), delavirdine (Rescriptor), stavudine (Zerit), efavirenz (Sustiva), zidovudine (Retrovir), and nelfinavir (Viracept) were

Blood disorders common in antiretroviral-exposed infants  -  May 21, 2007
Aidsmap,The anaemia tended to be worse in those children exposed to potent HIV therapy in the womb rather than zidovudine with or without an NRTI.

FDA Sounds Alert on Anemia Drugs  -  May 1, 2007
Journal of American Medical Association (subscription),Understand that in cancer patients whose anemia is caused by chemotherapy and in patients with HIV whose anemia is caused by zidovudine, there are no data

China and HIV — A Window of Opportunity  -  May 2, 2007
New England Journal of Medicine (subscription),Relying almost entirely on generic drugs produced in China, the country's first-line therapy regimens — zidovudine, didanosine, and nevirapine or zidovudine

New anaemia med warnings  -  May 12, 2007
Health24.com,...for major surgery to reduce potential blood transfusions and for the treatment of anaemia due to zidovudine therapy in HIV patients, the FDA said.

Twin pregnancies involve greater risk of mother-to-child HIV ...  -  May 9, 2007
Aidsmap,Between 1994 and 1996, mothers were provided with AZT (zidovudine) monotherapy, and after 1997 potent combinations of anti-HIV drugs were provided during

Africa: Q&A on Second-Line HIV/Aids Treatment  -  May 8, 2007
AllAfrica.com,A. The key “next generation� first-line regimens include the same medicines as today’s leading first-line regimens except that tenofovir (TDF) or zidovudine

Strides Arcolab ends JV with US firm  -  May 2, 2007
Business Standard,It has tentative approval for a fixed dose combination of anti-retroviral (ARV) drugs Lamivudine, Zidovudine 150 mg and 300 mg tablets, co-packaged with

AZT causes genetic damage to infants; long-term cancer risk unknown  -  Apr 16, 2007
Aidsmap,Pregnant women with HIV in developed countries receive antiretroviral treatment as standard care during pregnancy and infants are given zidovudine for six

FDA Alerts Pharmacists About Mislabeling of HIV Drugs  -  Apr 11, 2007
MedPage Today,A letter sent to pharmacists said the incidents, which involved abacavir sulfate (Ziagen) and a combination of lamvudine and zidovudine (Combivir),

FDA Announces Important Notice About Combivir and Ziagen  -  Apr 10, 2007
PharmaLive.com (press release),Combivir Tablets (in a legitimate bottle) contain 150 milligrams of lamivudine and 300 milligrams of zidovudine; however, the misbranded bottles of Combivir

Isolated Case of Counterfeit Combivir on the Market  -  Apr 12, 2007
Facts and Comparisons,GlaxoSmithKline is informing health care professionals of an incident of misbranding of Ziagen (abacavir sulfate) as Combivir (lamivudine/zidovudine).

License to sign  -  Apr 4, 2007
Duke Chronicle,The first drug to treat AIDS, AZT (zidovudine), was approved by the FDA in 1987. Since then, a host of antiretroviral agents (ARVs) have significantly

HIV eradication unlikely following bone marrow transplantation  -  Apr 24, 2007
Aidsmap,...marrow transplant] (contrary to zidovudine alone used in cases described before 1996), the goal of HIV eradication was not achieved for this patient.�

Lawmakers Go After Amgen and J&J Over Off-Label Sales of Anemia Drugs  -  Apr 22, 2007
Lawyers and Settlements,...patients with cancer who are receiving chemotherapy, patients scheduled for major surgery, and HIV patients with anemia due to zidovudine therapy.

Gilead's Atripla, Lower Costs Provide Lift To First Quarter  -  Apr 22, 2007
BioWorld Online,...which could be low if more patients switch to Atripla from Combivir (lamivudine and zidovudine, GlaxoSmithKline plc) and Sustiva (efavirenz,

Narrative Review: Antiretroviral Therapy to Prevent the Sexual ...  -  Apr 16, 2007
Annals of Internal MedicineData are available for the levels of intracellular phosphorylated forms of tenofovir, zidovudine, and lamivudine in mononuclear cells isolated from the male

Drug Used To Prevent HIV Transmission From Mother To Child Damages DNA  -  Apr 9, 2007
Medical News Today (press release),..."Elevated Frequencies of Micronucleated Erthrocytes in Infants Exposed to Zidovudine In Utero and Postpartum to Prevent Mother-to-Child Transmission of HIV

Adverse effects of ARVs  -  Apr 1, 2007
ZimDaily,Zidovudine. Main side effects are anaemia (reduced number of red blood cells, required for oxygen distribution in the blood) and reduced number of white

The HIV Resurgence  -  Apr 17, 2007
Walrus Magazine,Her doctor gave her between two and four years to live and prescribed zidovudine (azt). Sick, constantly tired, and overwhelmed, Binder eventually quit her

Amgen and J&J Funnel Tax Dollars Through Kidney and Cancer Patients  -  Apr 17, 2007
Lawyers and Settlements,...patients scheduled for major surgery to reduce potential blood transfusions, and for the treatment of anemia due to zidovudine therapy in HIV patients.

Drug Used To Prevent HIV Transmission From Mother To Child Damages DNA  -  Apr 12, 2007
Medical News Today (press release),Fortunately, antiretroviral drug combinations, which typically include AZT (zidovudine), a nucleoside reverse transcriptase inhibitor (NRTI), have reduced

Breastfeeding Benefits in Some HIV Settings  -  Apr 10, 2007
Journal of American Medical Association (subscription),She noted that a previous study in Botswana found that children who were breastfed (and given zidovudine) were more likely to develop postnatal HIV

UPI Health Correspondent  -  Apr 10, 2007
United Press InternationalThat precaution is advised in view of findings that suggest AZT (zidovudine) can cause genetic damage that may increase future cancer risk, scientists said

Update on Opt-Out Testing and Initial Antiretroviral Therapy ...  -  Apr 2, 2007
Medscape (subscription)The NRTI options were 3TC or FTC combined with stavudine (d4T), TDF, or zidovudine (ZDV). The surprise in this analysis was the lipid effect of EFV when

Ortho Biotech Revises Prescribing Information for PROCRIT(R ...  -  Apr 3, 2007
Drug Newswire (press release),...with chronic kidney disease who are not on dialysis, who are being treated with zidovudine for HIV infection, and to reduce the need for transfusion in

d4T dose can be reduced without loss of effectiveness, meta ...  -  Apr 2, 2007
Aidsmap,Efficacy and safety of half dose compared to full dose stavudine (d4T) and zidovudine (AZT) in combination with didanosine (ddI) in Thai HIV-infected

The Top 14 Most Counterfeited Medications  -  Mar 28, 2007
ScienceBlogsTrizivir (abacavir/lamivudine/zidovudine - used in the treatment of HIV). 12. Viagra (sildenafil - you know this one for sure)

Nations Defend HIV Drugs With Tests for Hardy Strains (Update1)  -  25 Feb 2007
BloombergCountries with small health budgets depend on cheap drugs, such as generic zidovudine, to combat HIV, which infects about 40 million people worldwide.

Aurobindo Pharma gets registrations for ARVs from Botswana  -  Feb 22, 2007
Myiris.com,The company has announced that the DRU (drugs regulatory unit) of Botswana has registered Lamivudine and Zidovudine tablet, Zidovudine oral solution 50 mg

Aurobindo registers 9 anti-AIDS products in Botswana  -  Feb 21, 2007
Reuters India,The products are Lamivudine and Zidovudine tablet, Zidovudine oral solution 50 mg/5 ml, Nevirapine Oral Suspension 50 mg/ ml Lamivudine oral solution 10

Off-Label Use of Aranesp Linked to Increased Mortality Risk  -  Feb 20, 2007
Medscape (subscription)For zidovudine-treated HIV patients and those with chronic renal failure (CRF) receiving initial treatment, hemoglobin should be measured once and twice

Despite ready reckoner, docs hurry with anti-retroviral therapy ...  -  Feb 9, 2007
Pune Newsline,Pune, February 9: * Shama (name changed) is HIV positive, her CD4 count is low and she has to take zidovudine, which can cause anaemia in some patients.

India's Cipla, Glenmark get tentative FDA nods  -  Feb 8, 2007
ReutersThe tentative approval is also for zidovudine and nevirapine, also AIDS drugs. Drug maker Glenmark Pharmaceuticals Ltd. (GLEN.BO: Quote, Profile, Research)

Cipla, Glenmark get tentative FDA nods  -  Feb 8, 2007
Economic Times,The tentative approval is also for zidovudine and nevirapine, also AIDS drugs. Drug maker Glenmark Pharmaceuticals Ltd.= has received tentative approval for

Clinical Cases in Neurology From Johns Hopkins -- Case 15: When a ...  -  Jan 31, 2007
Medscape (subscription)Medications at the time of presentation included trimethoprim-sulfamethoxazole, atazanavir, tenofovir, valacyclovir, and lamivudine/zidovudine.

British research shows herpes drug helps control HIV  -  Feb 22, 2007
Xinhua,This is the same effect one would expect if the women had been given an anti-HIV drug such as Zidovudine (AZT), according to Mayaud.

Indian pharmaceutical companies: innovative HIV drug reformulations  -  Feb 8, 2007
Pharmaceutical Business ReviewThe FDA has tentatively approved new HIV drug co-formulations combining lamivudine, zidovudine (both originally developed by GSK) and nevirapine (by

Exploiting natural HIV defence  -  Feb 9, 2007
BiopharmaReporter.com,The first ever HIV drug was zidovudine. It is a nucleoside molecule and although it was originally developed to treat cancer in the 1960s, it was dropped

Cipla and Glenmark get tentative nods from USFDA  -  Feb 9, 2007
Myiris.com,The tentative approval is also for zidovudine and nevirapine, also AIDS drugs. Meanwhile, drug maker Glenmark Pharmaceuticals has also received tentative

Botswana: Drug Patents And Their Implications On ARV Therapy Access  -  Feb 7, 2007
AllAfrica.com,One recent example is that of Combivir_, a first line drug that contains two pre-1995 drugs, zidovudine and lamivudine. The two separate drugs can be copied

Emergency HIV Prevention  -  Feb 6, 2007
ZimDaily,...will receive either a single dose of Nevirapine or receive a short course of Zidovudine (Please note: strategy largely depends on clinical setting).

Be careful if using fosamprenavir/ritonavir for PEP, and did HCV ...  -  Jan 31, 2007
Aidsmap,Severe liver toxicity in postexposure prophylaxis for HIV infection with zidovudine, lamivudine and fosamprenavir/ritonavir regimen. AIDS 21: 268 – 269,

The Struggle for Affordable Medicines  -  Jan 30, 2007
The Progress ReportEssentially, GSK sought a 20-year monopoly for combining two already known drugs – lamivudine and zidovudine, neither of which are patentable in India

Little boys too not safe anymore  -  Jan 30, 2007
Newindpress (subscription),A 28-day-regimen of zidovudine and lamivudine provides postexposure prophylaxis for HIV and should be started as soon as possible preferably within 72 hours

Gilead Sciences Announces Fourth Quarter and Full Year 2006 ...  -  Feb 1, 2007
PharmaLive.com (press release),This study compares a once-daily regimen of Viread, Emtriva and Sustiva to a twice-daily regimen of Combivir(R) (lamivudine/zidovudine) with Sustiva once

Delay in use of nevirapine-based AIDS treatment can improve outcomes  -  Jan 11, 2007
PressZoom (press release),Nevirapine, given once during labor, either alone or in combination with a short course of zidovudine (AZT) or other antiretroviral medications,

Delay in use of nevirapine-based AIDS treatment can improve outcomes  -  Jan 16, 2007
Hindu,This press release issued by Eurekalert says that nevirapine, given once during labour, either alone or in combination with a short course of zidovudine

Hope for HIV mothers protecting baby at birth  -  Jan 10, 2007
New Scientist (subscription),This means they fail to respond to the most commonly available HIV treatment – a combination therapy consisting of nevirapine, lamivudine and zidovudine

Maternal nevirapine-based ART more effective if delayed for more ...  -  Jan 10, 2007
Aidsmap,...(All of the women in the study were given zidovudine from 34 weeks into their pregnancies through delivery; similar to nevirapine, zidovudine reduces HIV

Women's Response to Anti-HIV Therapy Improved  -  Jan 12, 2007
Kansas City infoZine,Nevirapine, given once during labor, alone or in combination with a short course of zidovudine (AZT) during pregnancy, provides an inexpensive,

Post-Peripartum Use of Viramune Safe After Six-Month Wait  -  Jan 11, 2007
MedPage Today,In the United States, HIV-positive women typically are given Retrovir (zidovudine) for prevention of mother-to-child viral transmission, starting at 14 to

Nevirapine delay may help  -  Jan 11, 2007
Health24.com,...received a single dose of nevirapine or a placebo during labour, along with a short course of the antiretroviral drug zidovudine (AZT) during pregnancy.

Response to Antiretroviral Therapy after a Single, Peripartum Dose ...  -  Jan 10, 2007
New England Journal of Medicine (subscription),All women were treated with antenatal zidovudine. The primary end point for mothers and infants was virologic failure by the 6-month visit after initiation

Breastfeeding does not contribute to mortality among HIV-positive ...  -  Jan 10, 2007
Aidsmap,All women were given “standard antenatal care as well as short-course zidovudine [AZT]� according to the CDC Thai regimen. Follow-up was done at the time of

HIV patients may have to pop pills just once a day  -  Jan 5, 2007
Pune Newsline,This is because a drug like Zidovudine (ZDV) cannot be given just once a day,� Tripathy said. In the randomised trial, one group of 33 HIV infected

Glaxo withdraws patent plea for asthma drug  -  Dec 21, 2006
Times of India,In March, it was forced to withdraw its patent application on a fixed dose combination of zidovudine and lamivudine, an important AIDS medicine.

Study Examines Impact of Breast-Feeding on HIV-1 Viral Loads  -  Dec 22, 2006
Kaiser network.org,All of the women received the short-course antiretroviral treatment zidovudine and standard antenatal care to reduce the risk of mother-to-child HIV

Medivir Outlicenses Two HIV Candidates to Presidio Pharmaceuticals  -  Dec 20, 2006
Genetic Engineering News (press release),Additionally, recent in vitro results indicate that co-administration of alovudine and zidovudine increases the safety margin.

Medivir Outlicenses the Antiviral Compounds Alovudine (MIV-310 ...  -  Dec 20, 2006
PharmaLive.com (press release),Recent in vitro results indicate that coadministration of alovudine and zidovudine increases the safety margin and leads to a synergistic effect against HIV

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,...more quickly than resistance mutations to the nucleosides known as “thymidine analogues� – zidovudine (AZT, Retrovir) and stavudine (d4T, Zerit).

Buy Ambien  -  Dec 22, 2006
Indymedia Colombia,...genital episodes these or acyclovir Fosphenytoin phenytoin probenecid zidovudine, AZT Tell your doctor and pharmacist medication tramadol drug dose,

Antiretroviral Therapy for HIV: New Data From HIV 8 in Glasgow  -  Dec 26, 2006
Medscape (subscription)Furthermore, the risk for anemia will clearly be reduced by avoiding zidovudine coadministration with this HCV therapy. Figure 3 summarizes the main results

Antiretroviral Therapy for HIV: New Data From HIV 8 in Glasgow  -  26 Dec 2006
Medscape (subscription)Furthermore, the risk for anemia will clearly be reduced by avoiding zidovudine coadministration with this HCV therapy. Figure 3 summarizes the main results

FDA Safety Changes: Ortho Evra, Avastin, Trizivir  -  Dec 13, 2006
Medscape (subscription)On August 11, the FDA approved safety labeling revisions for abacavir sulfate/lamivudine/zidovudine tablets (Trizivir, made by GlaxoSmithKline) to warn of

South Africa: Scientists Warn State-Supplied Aids Drug Poses ...  -  Dec 6, 2006
AllAfrica.com,If patients develop severe side-effects or resistance, they switch to "second-line therapy", based on zidovudine (AZT), didanosine (ddI),

96-Week Data From Gilead’s Study 934 Comparing Viread ® and ...  -  Dec 15, 2006
Business Wire (press release),The study article, “Tenofovir Disoproxil Fumarate, Emtricitabine, and Efavirenz Versus Fixed-Dose Zidovudine/Lamivudine and Efavirenz in

BUAV: Research revolution needed to end hunt for Aids vaccine  -  Dec 1, 2006
Politics.co.uk,Conversely the BUAV’s exhaustive review of the scientific literature shows the most effective and widely used treatments for HIV/AIDS such as Zidovudine,

Triple nuke combination of AZT/3TC/tenofovir below current ...  -  Dec 17, 2006
Aidsmap,Virologic response of zidovudine, lamivudine, and tenofovir disoproxil fumarate combination in antiretroviral-naive HIV-1-infected patients.

Buy Ambien  -  Dec 22, 2006
Indymedia Colombia,...genital episodes these or acyclovir Fosphenytoin phenytoin probenecid zidovudine, AZT Tell your doctor and pharmacist medication tramadol drug dose,

Study Examines Impact of Breast-Feeding on HIV-1 Viral Loads  -  Dec 22, 2006
Kaiser network.org,All of the women received the short-course antiretroviral treatment zidovudine and standard antenatal care to reduce the risk of mother-to-child HIV

Glaxo withdraws patent plea for asthma drug  -  Dec 21, 2006
Times of India,In March, it was forced to withdraw its patent application on a fixed dose combination of zidovudine and lamivudine, an important AIDS medicine.

To Screen or Not to Screen: Is That Really the Question?  -  Dec 4, 2006
Annals of Internal MedicineThe discovery that zidovudine prophylaxis reduced perinatal transmission by two thirds led directly to a recommendation to screen all pregnant women.

Medivir Outlicenses Two HIV Candidates to Presidio Pharmaceuticals  -  Dec 20, 2006
Genetic Engineering News (press release),Additionally, recent in vitro results indicate that co-administration of alovudine and zidovudine increases the safety margin.

Medivir Outlicenses the Antiviral Compounds Alovudine (MIV-310 ...  -  Dec 20, 2006
PharmaLive.com (press release),Recent in vitro results indicate that coadministration of alovudine and zidovudine increases the safety margin and leads to a synergistic effect against HIV

Emergence of resistance mutations: a comparison between drug classes  -  Dec 19, 2006
Aidsmap,...more quickly than resistance mutations to the nucleosides known as “thymidine analogues� – zidovudine (AZT, Retrovir) and stavudine (d4T, Zerit).

Kenya: Government Introduces Combination Therapy for PMTCT  -  Dec 4, 2006
AllAfrica.com,HIV-positive pregnant women in Kenya may soon receive the AIDS drug Zidovudine, also known as AZT, alongside single-dose Nevirapine, a combination shown to

KENYA: Government introduces combination therapy for PMTCT  -  Dec 4, 2006
Kenya London News,NAIROBI, (PLUSNEWS) - HIV-positive pregnant women in Kenya may soon receive the AIDS drug Zidovudine, also known as AZT, alongside single-dose Nevirapine,

Breakthrough deal signed for paediatric HIV drugs  -  Dec 1, 2006
Pharma Times (subscription),The other ARVs for which the Clinton Foundation has negotiated price reductions include abacavir, didanosine, efavirenz and zidovudine.

President Clinton Announces Breakthroughs In HIV/AIDS Treatment ...  -  Nov 30, 2006
Medical News Today (press release),...included in the pediatric FDC, the other ARVs for which CHAI has negotiated price reductions include abacavir, didanosine, efavirenz and zidovudine.

Research and Markets: Cipla Manufactures Apis And Formulation ...  -  Nov 27, 2006
PharmaLive.com (press release),Cipla claims to have been the first local manufacturer to introduce a number of products to the Indian market, including the antiretrovirals zidovudine,

Pioneers in AIDS Care — Reflections on the Epidemic's Early Years  -  Nov 29, 2006
New England Journal of Medicine (subscription),It was hard to forget the exhilaration many had felt when zidovudine (earlier known as azidothymidine, or AZT), the first antiretroviral drug,


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